Master Yi - League of Legends Champion
Win Rate
50.7%
Pick Rate
4.6%

Master Yivs Karthus

AFighterAssassin
Patch26.4
Matches1,089,240
LaneAll Lanes
TierAll Tiers
Last UpdatedFeb 28, 2026
MethodologyData Methodology

Master Yi vs Karthus is a decisive matchup in LoL patch 26.4. Master Yi wins with a 59.3% win rate (+18.5%) over Karthus based on 54 games. Karthus wins the early laning phase while Master Yi scales better into the late game. Below you'll find the best Master Yi build, runes, laning stats, and strategies for the Master Yi vs Karthus matchup.

Master Yi Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Master Yi performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Karthus - 59.3% win rateKarthus(59.3%)
Master Yi - 59.3% win rate in this matchup
Master Yi
59.3% WR
VS
Karthus vs Master Yi matchup - 40.7% win rate
Karthus
40.7% WR

Who Wins the Master Yi vs Karthus Matchup?

Master Yi wins the Master Yi vs Karthus matchup
Winner
Master Yi
Matches: 54
59.3%
Win Rate
40.7%
1.2
CS / min
1.2
781
DMG / min
1,000
14,473
Gold / game
13,576
419
Heal / min
302
875
DMG Mitigated / min
490
0.2
CC / min
0.5
48.0%
Early Game WR
52.0%
69.0%
Late Game WR
31.0%

Master Yi vs Karthus Matchup Summary

The Master Yi vs Karthus matchup is a decisive matchup in League of Legends ranked play. Based on 54 recent matches analyzed, Master Yi wins with a 59.3% win rate compared to Karthus's 40.7%, giving Master Yi a 18.5 percentage point advantage. Game phase dynamics play a critical role here: Karthus controls the early laning stage, but Master Yi outscales as the game goes longer. The matchup shifts dramatically depending on game length — Karthus needs to press advantages before Master Yi reaches their power spikes, while Master Yi should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Karthus leads by 0.3s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Master Yi players can confidently pick into Karthus and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Karthus away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Master Yi vs Karthus Laning Phase Breakdown

Master Yi wins the laning phase against Karthus in League of Legends

Master Yi is favored during the laning phase against Karthus, winning 3 out of 5 key stat categories. Master Yi holds advantages in farming, gold income and sustain, making them the stronger laner in this matchup.

Farming
1.2Master Yi
1.2Karthus
Master Yi and Karthus farm at nearly identical rates in this matchup, with only a 0.0 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
781Master Yi
1,000Karthus
Karthus heavily out-damages Master Yi by 220 DMG/min, dominating both short trades and all-in fights. Master Yi should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Karthus's sustained damage advantage take over.
Economy
14,473Master Yi
13,576Karthus
Master Yi generates a commanding 897 more gold per game than Karthus. This substantial economic advantage means Master Yi consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Karthus should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.2Master Yi
0.5Karthus
Both Master Yi and Karthus provide similar amounts of crowd control (0.3s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
1,294Master Yi
792Karthus
Master Yi vastly out-sustains Karthus, healing and mitigating 502 more damage per minute. This massive durability gap means Master Yi can absorb significant punishment and remain in lane while Karthus is forced to recall. Building grievous wounds early is essential for Karthus, and focusing on burst trade patterns rather than sustained fights is critical.

Best Master Yi Build Against Karthus

Mercury's Treads is the optimal boots choice against Karthus, providing the mobility and stats Master Yi needs most in this matchup. The top-performing core items for Master Yi against Karthus are Kraken Slayer, Guinsoo's Rageblade and Wit's End. This combination gives Master Yi an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 57.1% win rate across 7 games — well above average and making it the top item path against Karthus. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Master Yi vs Karthus matchup.

Early Game vs Late Game

Early Game
Karthus
52.0%
+4.0% advantage
Master Yi early game win rateMaster Yi48.0%
Karthus early game win rateKarthus52.0%
Late Game
Master Yi
69.0%
+37.9% advantage
Master Yi late game win rateMaster Yi69.0%
Karthus late game win rateKarthus31.0%

During the early laning phase (first 15 minutes), Karthus has a meaningful 52.0% win rate, outperforming Master Yi by 4.0 percentage points. Karthus players should look to press this advantage through aggressive trades, wave priority, and early jungle coordination.

Master Yi is far superior in the late game (25+ minutes), boasting a 69.0% win rate — 37.9 points above Karthus. Extended games heavily favor Master Yi, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Karthus must aggressively press their early advantage and close out the game before Master Yi reaches their scaling breakpoints. If Master Yi survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Master Yi Runes Against Karthus

Domination rune tree - Master Yi primary runes vs KarthusDomination
Hail of Blades - best Master Yi rune vs KarthusSudden Impact - best Master Yi rune vs KarthusGrisly Mementos - best Master Yi rune vs KarthusTreasure Hunter - best Master Yi rune vs Karthus
Precision rune tree - Master Yi secondary runes vs KarthusPrecision
Legend: Alacrity - best Master Yi rune vs KarthusTriumph - best Master Yi rune vs Karthus
77.8% WR

Running Domination primary with Precision secondary allows Master Yi to press their advantage against Karthus, amplifying the strengths that make this a favorable matchup.


Master Yi matchup data for League of Legends patch 26.4. The table below shows Master Yi's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Master Yi build, runes, laning stats, and early vs late game analysis for that specific matchup.

Master Yi matchup win rates and stats in League of Legends patch 26.4
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
50.09%5531.277813,55753.6%46.6%
51.73%3481.385613,63846.9%56.8%
53.69%3391.281513,83350.4%56.1%
44.41%3051.974313,25843.7%45.1%
50.51%3001.478212,98047.9%52.9%
47.95%2931.376913,25944.8%50.3%
42.96%2911.372913,30345.0%41.5%
49.02%2581.274713,30356.1%43.9%
56.52%2541.371413,29752.5%60.3%
45.45%2531.271012,74645.6%45.3%
50.86%2342.095413,17155.3%46.6%
39.32%2071.373414,22132.4%43.0%
55.34%2072.181512,57359.0%50.6%
51.96%2051.379213,19549.0%54.7%
55.67%2041.279713,52457.1%54.3%
56.92%1951.282914,06953.0%59.8%
53.61%1951.385514,85755.1%52.6%
56.45%1891.476513,61852.2%60.6%
54.55%1771.382713,78948.2%60.4%
53.25%1541.275613,74850.7%55.7%
55.19%1541.380014,18152.7%57.5%
58.55%1531.283113,72462.7%55.3%
48.65%1502.876913,12849.2%48.2%
54.35%1391.374713,60246.5%60.0%
48.15%1372.579114,53644.2%50.6%
54.20%1311.282813,91154.4%54.0%
56.92%1311.181813,87547.2%63.6%
57.38%1241.576813,16155.9%58.7%
48.25%1141.881714,12746.8%49.3%
51.85%1103.385312,85854.4%50.0%
50.00%1091.183813,52740.4%60.8%
43.52%1081.271613,31346.1%41.1%
41.00%1013.784412,65639.5%42.1%
54.55%1001.683713,05251.0%58.3%
52.58%971.478413,85953.1%52.1%
53.61%972.288813,53151.2%55.6%
61.46%962.387813,62667.3%54.5%
51.61%951.479813,66145.2%56.9%
48.42%951.883514,24054.8%43.4%
57.61%931.782914,56158.3%57.1%
37.08%902.671812,69638.1%36.2%
48.86%881.386113,10848.7%49.0%
51.32%771.682212,88051.1%51.6%
57.14%771.581213,73647.1%65.1%
56.76%741.583313,18956.4%57.1%
49.30%722.574612,95644.4%54.3%
43.66%711.170512,70238.9%48.6%
71.43%701.587513,73748.5%91.9%
37.14%703.286113,11721.9%50.0%
45.31%655.590713,11117.6%55.3%
33.87%622.871612,08135.3%32.1%
56.67%604.889613,46547.8%62.2%
43.64%551.274113,92732.0%53.3%
59.26%541.278114,47348.0%69.0%
43.14%515.076811,90227.3%55.2%
50.00%471.376214,56041.2%55.2%
54.35%465.797413,78742.9%64.0%
66.67%452.481213,43372.2%63.0%
62.22%456.184712,84350.0%70.4%
48.89%453.892312,67055.0%44.0%
53.49%431.988614,65346.1%56.7%
51.28%394.096613,47062.5%43.5%
46.15%391.274812,57352.6%40.0%
56.41%392.079914,12250.0%61.9%
47.37%396.092713,25055.6%40.0%
68.42%381.984414,45271.4%66.7%
45.95%375.685213,84744.4%46.4%
34.29%365.172411,30416.7%43.5%
38.89%365.682511,40150.0%25.0%
45.45%334.580912,61744.4%46.7%
38.71%316.11,00513,74353.3%25.0%
55.17%291.472813,18460.0%50.0%
53.85%286.091813,44360.0%45.5%
50.00%283.174813,52733.3%62.5%
33.33%254.286111,86537.5%25.0%
60.00%251.368013,63650.0%66.7%
50.00%241.278311,55250.0%50.0%
34.78%241.870212,71457.1%25.0%
60.87%232.972513,25050.0%66.7%
40.91%225.781112,33150.0%35.7%
45.45%226.090612,03341.7%50.0%
47.62%215.31,08413,56328.6%57.1%
66.67%214.589413,73875.0%61.5%
50.00%206.694712,54654.5%44.4%
42.11%196.11,00412,12640.0%44.4%
63.16%196.684413,38555.6%70.0%
72.22%182.488514,21471.4%72.7%
38.89%185.372110,47242.9%36.4%
37.50%164.681713,24050.0%25.0%
33.33%151.355512,62312.5%57.1%
50.00%144.883612,32657.1%42.9%
53.85%134.191213,12057.1%50.0%
69.23%136.189312,98175.0%60.0%
53.85%136.076111,19666.7%25.0%
30.77%135.568012,32133.3%28.6%
46.15%135.793815,22825.0%55.6%
61.54%135.873612,49060.0%62.5%
46.15%135.51,01412,04350.0%42.9%
58.33%123.372212,80471.4%40.0%
50.00%122.070312,26171.4%20.0%
58.33%124.780312,15760.0%57.1%
54.55%113.695013,24266.7%50.0%
45.45%115.591712,99650.0%44.4%
63.64%115.691513,63560.0%66.7%
45.45%113.869611,98650.0%42.9%
54.55%114.91,16915,13850.0%60.0%
77.78%104.876911,42085.7%50.0%
50.00%104.868012,58750.0%50.0%
44.44%96.396812,14166.7%33.3%
77.78%96.089215,86350.0%85.7%
37.50%94.41,01211,30440.0%33.3%
37.50%84.58009,98040.0%33.3%
62.50%84.371910,66550.0%100.0%
75.00%84.41,14016,45750.0%83.3%
71.43%75.31,19317,0750.0%83.3%
57.14%72.278114,03850.0%60.0%
85.71%75.499414,259100.0%66.7%
57.14%75.575711,57550.0%66.7%
71.43%75.01,29317,00450.0%80.0%
57.14%73.979213,16866.7%50.0%
0.00%65.41,23816,4900.0%0.0%
33.33%66.11,04814,23550.0%0.0%
83.33%61.977711,627100.0%50.0%
0.00%64.590517,1970.0%0.0%
100.00%52.257410,864100.0%100.0%
40.00%53.076713,77250.0%33.3%
40.00%52.61,11015,05250.0%33.3%
80.00%55.61,10715,894100.0%50.0%
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Master Yi vs Karthus - Frequently Asked Questions

How does Master Yi do against Karthus in League of Legends?

Master Yi wins the Master Yi vs Karthus matchup with a 59.3% win rate compared to Karthus's 40.7%, a 18.5 percentage point difference. This data is based on 54 recent ranked games in patch 26.4.

How does Master Yi do against Karthus in the early game?

In the early game, Karthus has the advantage against Master Yi with a 52.0% win rate versus 48.0%. Karthus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Master Yi do against Karthus in the late game?

In the late game, Master Yi takes over the Master Yi vs Karthus matchup with a 69.0% win rate compared to 31.0%. Master Yi scales better into team fights and objective contests after 25 minutes.

Who wins the Master Yi vs Karthus matchup?

Master Yi wins the matchup against Karthus with a 59.3% win rate in League of Legends patch 26.4. The 18.5 percentage point advantage means Master Yi is significantly favored in this lane matchup based on 54 games analyzed.

What is the best Master Yi build against Karthus?

The best Master Yi build against Karthus includes Kraken Slayer, Guinsoo's Rageblade, Wit's End with Mercury's Treads. This build achieves a 57.1% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Master Yi runes against Karthus?

The best Master Yi runes against Karthus use the Domination primary tree with Precision secondary. This rune setup achieves a 77.8% win rate in the Master Yi vs Karthus matchup. See the full rune breakdown in the matchup comparison above.

Does Master Yi counter Karthus?

Yes, Master Yi has a favorable matchup against Karthus with a 59.3% win rate. Master Yi strongly counters Karthus in lane based on current patch 26.4 data.

How do I play Master Yi against Karthus?

When playing Master Yi against Karthus, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Karthus. Build the recommended items and runes for this specific matchup for the best results.