
Triple Tonic Overview
Upon reaching level 6, gain an Elixir of Force.
Upon reaching level 9, gain an Elixir of Skill.
Triple Tonic Early vs Late Game Performance's win rate varies throughout the game based on match duration. Triple Tonic Early vs Late Game Performance peaks at 51.24% win rate in 50+ minute games, while performing lowest at 48.61% in 15 minute games. Understanding Triple Tonic Early vs Late Game Performance's power spikes across game duration helps optimize your playstyle and decision-making.
Triple Tonic is most commonly used by Mage (31%), Marksman (28%) and Assassin (19%) champions.
These runes are most commonly used alongside Triple Tonic in League of Legends. Cash Back appears in 58.3% of builds with a 67.76% win rate, First Strike appears in 37.5% of builds with a 66.16% win rate, Cut Down appears in 33.3% of builds with a 72.90% win rate when paired with Triple Tonic.
When to Pick Triple Tonic
Strengths
- Solid win rate (50.66%) shows reliable performance
- Excellent synergy with Kai'Sa (82.35% WR)
- Strong synergy with Cash Back (58.3% pairing rate)
- Scales well into late game teamfights
Weaknesses
- Requires proper champion selection to maximize value
- Weaker early game requires safe laning phase
- Less effective on Support champions
- Other Inspiration runes may outperform in specific matchups
Strategic Tips
Pick Triple Tonic on champions like Lux that can fully utilize its effects. Avoid picking it on champions where other Inspiration runes provide more value.
Pair Triple Tonic with Cash Back and First Strike for the highest win rate combinations.
Triple Tonic scales into the late game. Focus on farming safely and reaching your power spikes before committing to fights.
These runes are part of the same Inspiration rune tree as Triple Tonic. Glacial Augment, Unsealed Spellbook, First Strike, and 8 more runes can be combined with Triple Tonic in your rune page.
Triple Tonic - Frequently Asked Questions
What is Triple Tonic and what does it do in League of Legends?
Triple Tonic is a rune in the Inspiration rune tree. It currently has a 50.66% win rate and 6.13% pick rate across 24 champions in ranked play.
Is Triple Tonic good in the current meta?
Triple Tonic has a 50.66% win rate in the current patch, making it a solid option. The most popular champions using Triple Tonic are Graves, Bel'Veth, Aphelios.
What champion class benefits most from Triple Tonic?
Mage champions benefit most from Triple Tonic, making up 31% of its usage. Marksman (28%) and Assassin (19%) also commonly use this rune.
What runes pair well with Triple Tonic?
The best runes to pair with Triple Tonic are Cash Back, First Strike, Cut Down. Cash Back appears in 58.3% of builds featuring Triple Tonic with a 67.76% combined win rate.
Which champion has the highest win rate with Triple Tonic?
Sivir currently has the highest win rate with Triple Tonic at 52.20%, with a 4.96% pick rate in ranked games.

















