Triple Tonic - League of Legends Rune

Triple TonicOverview

Patch26.7
Matches949,984
TierAll Tiers
Last UpdatedApr 19, 2026
MethodologyData Methodology
Upon reaching level 3, gain an Elixir of Avarice.
Upon reaching level 6, gain an Elixir of Force.
Upon reaching level 9, gain an Elixir of Skill.

Ashe leads with 8.80% pick rate and 69.23% win rate, Miss Fortune leads with 7.61% pick rate and 75.86% win rate, Master Yi leads with 5.06% pick rate and 90.91% win rate.

Master Yi achieves 90.91% win rate (+40.47% diff), Camille achieves 88.89% win rate (+39.03% diff), Fiora achieves 84.21% win rate (+34.83% diff).

Triple Tonic Early vs Late Game Performance's win rate varies throughout the game based on match duration. Triple Tonic Early vs Late Game Performance peaks at 51.44% win rate in 25 minute games, while performing lowest at 48.39% in 50+ minute games. Understanding Triple Tonic Early vs Late Game Performance's power spikes across game duration helps optimize your playstyle and decision-making.

Triple Tonic is most commonly used by Fighter (31%), Marksman (22%) and Assassin (22%) champions.

These runes are most commonly used alongside Triple Tonic in League of Legends. Cash Back appears in 73.7% of builds with a 70.23% win rate, First Strike appears in 36.8% of builds with a 67.67% win rate, Cut Down appears in 31.6% of builds with a 73.09% win rate when paired with Triple Tonic.

When to Pick Triple Tonic

Triple Tonic is a Inspiration tree rune with a 50.57% win rate and 6.71% pick rate in the current patch. It's most effective on Fighter champions (31% of users). The most popular champions using Triple Tonic are Ashe, Miss Fortune, Master Yi.

Strengths

  • Solid win rate (50.57%) shows reliable performance
  • Excellent synergy with Master Yi (90.91% WR)
  • Strong synergy with Cash Back (73.7% pairing rate)
  • Scales well into late game teamfights

Weaknesses

  • Requires proper champion selection to maximize value
  • Weaker early game requires safe laning phase
  • Less effective on Tank champions
  • Other Inspiration runes may outperform in specific matchups

Strategic Tips

1

Champion Selection

Pick Triple Tonic on champions like Ashe that can fully utilize its effects. Avoid picking it on champions where other Inspiration runes provide more value.

2

Rune Synergies

Pair Triple Tonic with Cash Back and First Strike for the highest win rate combinations.

3

Game Phase Focus

Triple Tonic scales into the late game. Focus on farming safely and reaching your power spikes before committing to fights.

These runes are part of the same Inspiration rune tree as Triple Tonic. Glacial Augment, Unsealed Spellbook, First Strike, and 8 more runes can be combined with Triple Tonic in your rune page.

Get the MetaBot Desktop App

Level up your gameplay with real-time overlays, automatic game detection, and instant stats — all on your desktop.

In-game overlaysAuto game detectionMulti-game supportPersonal dashboard
Download NowFree download
🔍

Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.

Report an Issue

Triple Tonic - Frequently Asked Questions

What is Triple Tonic and what does it do in League of Legends?

Triple Tonic is a rune in the Inspiration rune tree. It currently has a 50.57% win rate and 6.71% pick rate across 19 champions in ranked play.

Is Triple Tonic good in the current meta?

Triple Tonic has a 50.57% win rate in the current patch, making it a solid option. The most popular champions using Triple Tonic are Ashe, Gwen, Camille.

What champion class benefits most from Triple Tonic?

Fighter champions benefit most from Triple Tonic, making up 31% of its usage. Marksman (22%) and Assassin (22%) also commonly use this rune.

What runes pair well with Triple Tonic?

The best runes to pair with Triple Tonic are Cash Back, First Strike, Cut Down. Cash Back appears in 73.7% of builds featuring Triple Tonic with a 70.23% combined win rate.

Which champion has the highest win rate with Triple Tonic?

Miss Fortune currently has the highest win rate with Triple Tonic at 51.60%, with a 7.61% pick rate in ranked games.