Triple Tonic - League of Legends Rune

Triple TonicBuilds

Patch26.7
Matches508,082
TierAll Tiers
Last UpdatedApr 10, 2026
MethodologyData Methodology
Upon reaching level 3, gain an Elixir of Avarice.
Upon reaching level 6, gain an Elixir of Force.
Upon reaching level 9, gain an Elixir of Skill.

Discover the 20 champions that use Triple Tonic in their primary rune builds. The top performing builds include Yunara (69.05% rune WR, +19.76% diff), Gwen (79.17% rune WR, +29.80% diff), Aphelios (77.78% rune WR, +26.92% diff). The "Rune WR Diff" column shows how much better or worse the rune build performs compared to the champion's overall win rate - positive values indicate the rune synergizes well with that champion.

Rank
Champion
Top Rune Build
Rune WR
Rune WR Diff
Rune PR
1
Lethal TempoPresence of MindLegend: BloodlineCoup de GraceCash BackTriple Tonic
69.05%+19.76%1.19%
2
ConquerorTriumphLegend: AlacrityLast StandCash BackTriple Tonic
79.17%+29.80%2.53%
3
Lethal TempoTriumphLegend: BloodlineCut DownCash BackTriple Tonic
77.78%+26.92%0.79%
4
Press the AttackPresence of MindLegend: AlacrityCut DownCash BackTriple Tonic
68.75%+20.84%0.87%
5
ConquerorPresence of MindLegend: BloodlineCut DownTriple TonicCash Back
80.00%+29.85%0.92%
6
First StrikeCash BackTriple TonicCosmic InsightBone PlatingUnflinching
67.57%+18.09%1.93%
7
Lethal TempoPresence of MindLegend: BloodlineCut DownCash BackTriple Tonic
80.95%+34.47%0.37%
8
Lethal TempoPresence of MindLegend: AlacrityCut DownCash BackTriple Tonic
63.16%+13.52%1.63%
9
First StrikeCash BackTriple TonicCosmic InsightSudden ImpactUltimate Hunter
75.00%+23.71%1.72%
10
First StrikeCash BackTriple TonicCosmic InsightCheap ShotTreasure Hunter
58.06%+9.00%3.88%
11
First StrikeMagical FootwearTriple TonicJack Of All TradesManaflow BandTranscendence
87.50%+37.27%0.74%
12
First StrikeCash BackTriple TonicCosmic InsightSudden ImpactTreasure Hunter
87.50%+40.28%0.69%
13
First StrikeCash BackTriple TonicCosmic InsightManaflow BandTranscendence
64.15%+12.31%1.09%
14
First StrikeCash BackTriple TonicCosmic InsightSudden ImpactTreasure Hunter
63.16%+12.46%1.15%
15
First StrikeMagical FootwearTriple TonicCosmic InsightCut DownPresence of Mind
70.00%+16.32%0.71%
16
Lethal TempoTriumphLegend: AlacrityLast StandCash BackTriple Tonic
58.06%+12.36%2.72%
17
Lethal TempoTriumphLegend: BloodlineCoup de GraceCash BackTriple Tonic
80.00%+34.23%0.56%
18
Press the AttackPresence of MindLegend: BloodlineCut DownTriple TonicCash Back
77.27%+30.68%0.92%
19
ConquerorTriumphLegend: HasteLast StandCash BackTriple Tonic
95.65%+45.89%0.74%
20
First StrikeMagical FootwearTriple TonicCosmic InsightSudden ImpactRelentless Hunter
56.67%+11.30%3.47%

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Triple Tonic Builds - Frequently Asked Questions

What are the best Triple Tonic builds in Patch 26.7?

The highest win rate Triple Tonic builds are Yunara (69.05% WR), Gwen (79.17% WR), Aphelios (77.78% WR). These builds have been tested across 20 champions in ranked play.

How do I build Triple Tonic on my champion?

Triple Tonic is typically used as part of a Inspiration build. The most successful Triple Tonic builds pair it with Cash Back, First Strike, Cosmic Insight. Check the builds table above to find the optimal rune page for your specific champion.

How many champions can use Triple Tonic effectively?

Currently, 20 champions use Triple Tonic in their optimal builds. The rune is most popular among Marksman champions (30% of users).Vel'Koz achieves the highest win rate at 53.68%.

What is the average win rate for Triple Tonic builds?

Triple Tonic builds average a 50.55% win rate across all champions. Top performers like Yunara and Gwen exceed this with win rates of 69.05% and 79.17% respectively.