Kassadin - League of Legends Champion
Win Rate
53.2%
Pick Rate
1.1%

Kassadinvs Karthus

SAssassinMage
Patch26.14
Matches81,210
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 17, 2026
MethodologyData Methodology

Kassadin vs Karthus is a decisive matchup in LoL patch 26.14. Karthus wins with a 100.0% win rate (+100.0%) over Kassadin based on 1 games. Kassadin wins the early laning phase while Karthus scales better into the late game. Below you'll find the best Kassadin build, runes, laning stats, and strategies for the Kassadin vs Karthus matchup.

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Kassadin Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Kassadin performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Kassadin - 0.0% win rate in this matchup
Kassadin
0.0% WR
VS
Karthus vs Kassadin matchup - 100.0% win rate
Karthus
100.0% WR

Who Wins the Kassadin vs Karthus Matchup?

Karthus wins the Kassadin vs Karthus matchup
Winner
Karthus
Matches: 1
0.0%
Win Rate
100.0%
6.1
CS / min
5.5
782
DMG / min
1,183
15,963
Gold / game
13,406
178
Heal / min
66
727
DMG Mitigated / min
439
0.1
CC / min
0.7
0.0%
Early Game WR
0.0%
0.0%
Late Game WR
100.0%

Kassadin vs Karthus Matchup Summary

The Kassadin vs Karthus matchup is a decisive matchup in League of Legends ranked play. Based on 1 recent matches analyzed, Karthus wins with a 100.0% win rate compared to Kassadin's 0.0%, giving Karthus a 100.0 percentage point advantage. Game phase dynamics play a critical role here: Kassadin controls the early laning stage, but Karthus outscales as the game goes longer. The matchup shifts dramatically depending on game length — Kassadin needs to press advantages before Karthus reaches their power spikes, while Karthus should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Karthus leads by 0.6s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Karthus has a strong advantage in this matchup. Kassadin players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Karthus overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Kassadin vs Karthus Laning Phase Breakdown

Kassadin wins the laning phase against Karthus in League of Legends

Kassadin is favored during the laning phase against Karthus, winning 3 out of 5 key stat categories. Kassadin holds advantages in farming, gold income and sustain, making them the stronger laner in this matchup.

Farming
6.1Kassadin
5.5Karthus
Kassadin edges out Karthus by 0.6 CS per minute — a moderate farming advantage that adds up to roughly 10 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Kassadin.
Damage
782Kassadin
1,183Karthus
Karthus heavily out-damages Kassadin by 401 DMG/min, dominating both short trades and all-in fights. Kassadin should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Karthus's sustained damage advantage take over.
Economy
15,963Kassadin
13,406Karthus
Kassadin generates a commanding 2,557 more gold per game than Karthus. This substantial economic advantage means Kassadin consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Karthus should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.1Kassadin
0.7Karthus
Karthus provides 0.6 seconds more crowd control per minute than Kassadin, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Karthus coordinate with their jungler and control the pace of skirmishes.
Sustain
905Kassadin
505Karthus
Kassadin vastly out-sustains Karthus, healing and mitigating 400 more damage per minute. This massive durability gap means Kassadin can absorb significant punishment and remain in lane while Karthus is forced to recall. Building grievous wounds early is essential for Karthus, and focusing on burst trade patterns rather than sustained fights is critical.

Best Kassadin Build Against Karthus

Spellslinger's Shoes is the optimal boots choice against Karthus, providing the mobility and stats Kassadin needs most in this matchup. The top-performing core items for Kassadin against Karthus are Rod of Ages, Zhonya's Hourglass and Malignance. This combination gives Kassadin an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Kassadin vs Karthus matchup.

Early Game vs Late Game

Early Game
Kassadin
0.0%
+0.0% advantage
Kassadin early game win rateKassadin0.0%
Karthus early game win rateKarthus0.0%
Late Game
Karthus
100.0%
+100.0% advantage
Kassadin late game win rateKassadin0.0%
Karthus late game win rateKarthus100.0%

The early game (first 15 minutes) is a toss-up between Kassadin and Karthus, with Kassadin holding a razor-thin 0.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Karthus is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Kassadin. Extended games heavily favor Karthus, whose kit and scaling make them a dominant force in team fights and objective control.

The power dynamics shift as the game progresses — Kassadin has the edge early, but Karthus gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Kassadin Runes Against Karthus

Inspiration rune tree - Kassadin primary runes vs KarthusInspiration
First Strike - best Kassadin rune vs KarthusCash Back - best Kassadin rune vs KarthusTriple Tonic - best Kassadin rune vs KarthusCosmic Insight - best Kassadin rune vs Karthus
Domination rune tree - Kassadin secondary runes vs KarthusDomination
Sudden Impact - best Kassadin rune vs KarthusUltimate Hunter - best Kassadin rune vs Karthus
0.0% WR

The Inspiration and Domination rune setup gives Kassadin the best tools to compete against Karthus in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Kassadin matchup data for League of Legends patch 26.14. The table below shows Kassadin's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Kassadin build, runes, laning stats, and early vs late game analysis for that specific matchup.

Kassadin matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
70.00%106.887311,57550.0%83.3%
70.00%106.487613,62750.0%83.3%
50.00%85.51,06913,338100.0%33.3%
25.00%86.375110,13825.0%25.0%
62.50%86.475510,94366.7%60.0%
42.86%76.091210,66766.7%25.0%
33.33%66.36307,74050.0%0.0%
80.00%56.11,43816,434100.0%75.0%
60.00%56.282316,214100.0%50.0%
40.00%56.972510,93466.7%0.0%
60.00%56.55746,77660.0%0.0%
80.00%57.085614,26450.0%100.0%
75.00%46.668611,933100.0%50.0%
0.00%35.91,01413,5500.0%0.0%
100.00%25.387214,4480.0%100.0%
50.00%26.597514,1140.0%50.0%
50.00%25.595916,4480.0%50.0%
50.00%25.65017,83050.0%0.0%
50.00%27.21,40414,605100.0%0.0%
0.00%16.85488,6240.0%0.0%
100.00%18.373715,3380.0%100.0%
0.00%16.178215,9630.0%0.0%
100.00%18.61,04814,087100.0%0.0%
0.00%17.786812,0170.0%0.0%

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Kassadin vs Karthus - Frequently Asked Questions

How does Kassadin do against Karthus in League of Legends?

Karthus wins the Kassadin vs Karthus matchup with a 100.0% win rate compared to Kassadin's 0.0%, a 100.0 percentage point difference. This data is based on 1 recent ranked games in patch 26.14.

How does Kassadin do against Karthus in the early game?

In the early game, Kassadin has the advantage against Karthus with a 0.0% win rate versus 0.0%. Kassadin players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Kassadin do against Karthus in the late game?

In the late game, Karthus takes over the Kassadin vs Karthus matchup with a 100.0% win rate compared to 0.0%. Karthus scales better into team fights and objective contests after 25 minutes.

Who wins the Kassadin vs Karthus matchup?

Karthus wins the matchup against Kassadin with a 100.0% win rate in League of Legends patch 26.14. The 100.0 percentage point advantage means Karthus is significantly favored in this lane matchup based on 1 games analyzed.

What is the best Kassadin build against Karthus?

The best Kassadin build against Karthus includes Rod of Ages, Zhonya's Hourglass, Malignance with Spellslinger's Shoes. Check the matchup breakdown above for the full item path and build order.

What are the best Kassadin runes against Karthus?

The best Kassadin runes against Karthus use the Inspiration primary tree with Domination secondary. This rune setup achieves a 0.0% win rate in the Kassadin vs Karthus matchup. See the full rune breakdown in the matchup comparison above.

Does Kassadin counter Karthus?

No, Kassadin struggles against Karthus with only a 0.0% win rate. Karthus has the advantage in this matchup. Kassadin players should focus on safe farming and avoiding extended trades to minimize Karthus's lead.

How do I play Kassadin against Karthus?

When playing Kassadin against Karthus, play cautiously and avoid Karthus's power spikes. Look for jungle assistance and team-dependent plays since Karthus has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.