Kassadinvs Vayne
Kassadin vs Vayne is a decisive matchup in LoL patch 26.10. Vayne wins with a 60.0% win rate (+20.0%) over Kassadin based on 5 games. Vayne wins the early laning phase while Kassadin scales better into the late game. Below you'll find the best Kassadin build, runes, laning stats, and strategies for the Kassadin vs Vayne matchup.
Kassadin Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Kassadin performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Vayne(40.0%)Who Wins the Kassadin vs Vayne Matchup?
Kassadin vs Vayne Matchup Summary
The Kassadin vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Vayne wins with a 60.0% win rate compared to Kassadin's 40.0%, giving Vayne a 20.0 percentage point advantage. Game phase dynamics play a critical role here: Vayne controls the early laning stage, but Kassadin outscales as the game goes longer. The matchup shifts dramatically depending on game length — Vayne needs to press advantages before Kassadin reaches their power spikes, while Kassadin should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Vayne leads by 0.2s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne has a strong advantage in this matchup. Kassadin players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Vayne overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Kassadin vs Vayne Laning Phase Breakdown
Vayne is favored during the laning phase against Kassadin, winning 4 out of 5 key stat categories. Vayne holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.
Best Kassadin Build Against Vayne
Spellslinger's Shoes is the optimal boots choice against Vayne, providing the mobility and stats Kassadin needs most in this matchup. The top-performing core items for Kassadin against Vayne are Rod of Ages, Zhonya's Hourglass and Malignance. This combination gives Kassadin an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Kassadin vs Vayne matchup.
Early Game vs Late Game
Kassadin0.0%Vayne100.0%Kassadin66.7%Vayne33.3%Vayne dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Kassadin. This lopsided early game means Vayne can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Kassadin is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Vayne. Extended games heavily favor Kassadin, whose kit and scaling make them a dominant force in team fights and objective control.
This matchup features a dramatic power shift: Vayne must aggressively press their early advantage and close out the game before Kassadin reaches their scaling breakpoints. If Kassadin survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.
Best Kassadin Runes Against Vayne
Inspiration
Domination
The Inspiration and Domination rune setup gives Kassadin the best tools to compete against Vayne in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Kassadin matchup data for League of Legends patch 26.10. The table below shows Kassadin's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Kassadin build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 54.76% | 84 | 6.5 | 803 | 11,721 | 47.6% | 61.9% | |
| 40.30% | 67 | 6.5 | 752 | 11,906 | 38.7% | 41.7% | |
| 52.54% | 59 | 6.1 | 864 | 12,536 | 53.9% | 51.5% | |
| 43.40% | 53 | 6.7 | 924 | 12,802 | 40.0% | 45.5% | |
| 59.62% | 52 | 6.5 | 945 | 11,928 | 58.1% | 61.9% | |
| 50.00% | 50 | 6.3 | 872 | 12,933 | 27.8% | 62.5% | |
| 48.00% | 50 | 6.5 | 849 | 12,727 | 33.3% | 61.5% | |
| 53.19% | 47 | 6.7 | 862 | 12,844 | 41.7% | 65.2% | |
| 57.45% | 47 | 6.7 | 1,016 | 11,603 | 66.7% | 41.2% | |
| 52.38% | 42 | 6.6 | 863 | 11,605 | 42.9% | 61.9% | |
| 60.98% | 41 | 6.7 | 933 | 12,438 | 38.1% | 85.0% | |
| 41.03% | 39 | 6.6 | 802 | 12,144 | 38.1% | 44.4% | |
| 29.41% | 34 | 5.8 | 799 | 11,292 | 16.7% | 43.8% | |
| 41.18% | 34 | 6.0 | 695 | 11,376 | 31.3% | 50.0% | |
| 41.18% | 34 | 6.8 | 814 | 11,776 | 35.0% | 50.0% | |
| 50.00% | 30 | 6.0 | 884 | 11,922 | 45.5% | 52.6% | |
| 30.00% | 30 | 5.9 | 823 | 13,044 | 33.3% | 27.8% | |
| 51.72% | 29 | 6.0 | 824 | 12,793 | 63.6% | 44.4% | |
| 53.57% | 28 | 6.3 | 979 | 13,554 | 50.0% | 55.0% | |
| 42.86% | 28 | 6.2 | 715 | 11,697 | 25.0% | 56.3% | |
| 34.62% | 26 | 7.0 | 823 | 13,821 | 33.3% | 35.7% | |
| 32.00% | 25 | 5.9 | 985 | 13,253 | 20.0% | 40.0% | |
| 62.50% | 24 | 6.3 | 796 | 11,555 | 70.0% | 57.1% | |
| 41.67% | 24 | 6.1 | 777 | 12,583 | 42.9% | 41.2% | |
| 41.67% | 24 | 6.2 | 1,003 | 13,808 | 40.0% | 42.9% | |
| 50.00% | 22 | 6.3 | 813 | 11,884 | 33.3% | 61.5% | |
| 59.09% | 22 | 6.7 | 900 | 12,435 | 44.4% | 69.2% | |
| 38.10% | 21 | 6.3 | 719 | 12,083 | 12.5% | 53.9% | |
| 57.14% | 21 | 5.4 | 736 | 12,645 | 50.0% | 61.5% | |
| 65.00% | 20 | 6.4 | 740 | 10,789 | 63.6% | 66.7% | |
| 60.00% | 20 | 5.6 | 768 | 11,851 | 25.0% | 83.3% | |
| 36.84% | 19 | 6.8 | 816 | 11,433 | 38.5% | 33.3% | |
| 68.42% | 19 | 6.5 | 779 | 13,076 | 66.7% | 69.2% | |
| 55.56% | 18 | 7.1 | 906 | 13,563 | 62.5% | 50.0% | |
| 35.29% | 17 | 6.1 | 677 | 9,794 | 33.3% | 37.5% | |
| 33.33% | 15 | 6.4 | 784 | 11,316 | 25.0% | 42.9% | |
| 50.00% | 14 | 5.8 | 819 | 12,707 | 60.0% | 44.4% | |
| 53.85% | 13 | 6.7 | 815 | 10,786 | 42.9% | 66.7% | |
| 69.23% | 13 | 6.3 | 742 | 12,751 | 80.0% | 62.5% | |
| 66.67% | 12 | 6.1 | 857 | 11,756 | 50.0% | 83.3% | |
| 45.45% | 11 | 6.2 | 821 | 11,418 | 60.0% | 33.3% | |
| 36.36% | 11 | 5.9 | 781 | 10,948 | 16.7% | 60.0% | |
| 54.55% | 11 | 6.6 | 1,100 | 14,385 | 20.0% | 83.3% | |
| 60.00% | 10 | 6.6 | 559 | 9,323 | 42.9% | 100.0% | |
| 60.00% | 10 | 7.3 | 868 | 12,019 | 66.7% | 50.0% | |
| 33.33% | 9 | 5.5 | 730 | 10,857 | 33.3% | 33.3% | |
| 44.44% | 9 | 5.6 | 754 | 10,847 | 40.0% | 50.0% | |
| 50.00% | 8 | 6.0 | 861 | 12,940 | 33.3% | 60.0% | |
| 50.00% | 8 | 6.1 | 830 | 11,813 | 50.0% | 50.0% | |
| 50.00% | 8 | 7.0 | 1,033 | 13,062 | 50.0% | 50.0% | |
| 50.00% | 8 | 6.8 | 630 | 11,655 | 40.0% | 66.7% | |
| 42.86% | 7 | 6.1 | 839 | 12,963 | 0.0% | 60.0% | |
| 0.00% | 7 | 6.8 | 780 | 11,020 | 0.0% | 0.0% | |
| 28.57% | 7 | 6.3 | 535 | 9,730 | 40.0% | 0.0% | |
| 71.43% | 7 | 6.1 | 985 | 13,203 | 100.0% | 50.0% | |
| 16.67% | 6 | 7.0 | 783 | 9,602 | 25.0% | 0.0% | |
| 50.00% | 6 | 7.0 | 869 | 9,543 | 50.0% | 50.0% | |
| 66.67% | 6 | 7.4 | 733 | 11,369 | 60.0% | 100.0% | |
| 40.00% | 5 | 6.3 | 612 | 11,121 | 0.0% | 66.7% | |
| 80.00% | 5 | 7.3 | 655 | 9,261 | 66.7% | 100.0% | |
| 40.00% | 5 | 5.7 | 811 | 12,759 | 0.0% | 50.0% | |
| 60.00% | 5 | 5.7 | 879 | 10,272 | 33.3% | 100.0% | |
| 60.00% | 5 | 5.0 | 596 | 8,191 | 33.3% | 100.0% | |
| 40.00% | 5 | 6.4 | 462 | 11,141 | 33.3% | 50.0% | |
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Kassadin vs Vayne - Frequently Asked Questions
How does Kassadin do against Vayne in League of Legends?
Vayne wins the Kassadin vs Vayne matchup with a 60.0% win rate compared to Kassadin's 40.0%, a 20.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.10.
How does Kassadin do against Vayne in the early game?
In the early game, Vayne has the advantage against Kassadin with a 100.0% win rate versus 0.0%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Kassadin do against Vayne in the late game?
In the late game, Kassadin takes over the Kassadin vs Vayne matchup with a 66.7% win rate compared to 33.3%. Kassadin scales better into team fights and objective contests after 25 minutes.
Who wins the Kassadin vs Vayne matchup?
Vayne wins the matchup against Kassadin with a 60.0% win rate in League of Legends patch 26.10. The 20.0 percentage point advantage means Vayne is significantly favored in this lane matchup based on 5 games analyzed.
What is the best Kassadin build against Vayne?
The best Kassadin build against Vayne includes Rod of Ages, Zhonya's Hourglass, Malignance with Spellslinger's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Kassadin runes against Vayne?
The best Kassadin runes against Vayne use the Inspiration primary tree with Domination secondary. This rune setup achieves a 100.0% win rate in the Kassadin vs Vayne matchup. See the full rune breakdown in the matchup comparison above.
Does Kassadin counter Vayne?
No, Kassadin struggles against Vayne with only a 40.0% win rate. Vayne has the advantage in this matchup. Kassadin players should focus on safe farming and avoiding extended trades to minimize Vayne's lead.
How do I play Kassadin against Vayne?
When playing Kassadin against Vayne, play cautiously and avoid Vayne's power spikes. Focus on safe farming — you outscale Vayne in the late game. Use the matchup-specific build and runes above to optimize your chances.