Vayne - League of Legends Champion
Win Rate
49.1%
Pick Rate
4.7%

Vaynevs Kassadin

DMarksmanAssassin
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 10, 2026
MethodologyData Methodology

Vayne vs Kassadin is a decisive matchup in LoL patch 26.11. Vayne wins with a 80.0% win rate (+60.0%) over Kassadin based on 5 games. Vayne holds the advantage in both the early and late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Kassadin matchup.

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Vayne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vayne - 80.0% win rate in this matchup
Vayne
80.0% WR
VS
Kassadin vs Vayne matchup - 20.0% win rate
Kassadin
20.0% WR

Who Wins the Vayne vs Kassadin Matchup?

Vayne wins the Vayne vs Kassadin matchup
Winner
Vayne
Matches: 5
80.0%
Win Rate
20.0%
6.2
CS / min
5.6
1,024
DMG / min
850
13,762
Gold / game
13,062
252
Heal / min
194
519
DMG Mitigated / min
768
0.4
CC / min
0.2
100.0%
Early Game WR
0.0%
66.7%
Late Game WR
33.3%

Vayne vs Kassadin Matchup Summary

The Vayne vs Kassadin matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Vayne wins with a 80.0% win rate compared to Kassadin's 20.0%, giving Vayne a 60.0 percentage point advantage. Vayne dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Kassadin players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Vayne leads by 0.2s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne players can confidently pick into Kassadin and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Kassadin away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vayne vs Kassadin Laning Phase Breakdown

Vayne wins the laning phase against Kassadin in League of Legends

Vayne is favored during the laning phase against Kassadin, winning 4 out of 5 key stat categories. Vayne holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
6.2Vayne
5.6Kassadin
Vayne edges out Kassadin by 0.5 CS per minute — a moderate farming advantage that adds up to roughly 8 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Vayne.
Damage
1,024Vayne
850Kassadin
Vayne heavily out-damages Kassadin by 174 DMG/min, dominating both short trades and all-in fights. Kassadin should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vayne's sustained damage advantage take over.
Economy
13,762Vayne
13,062Kassadin
Vayne earns 700 more gold per game than Kassadin, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Vayne slightly faster item completions.
Utility
0.4Vayne
0.2Kassadin
Both Vayne and Kassadin provide similar amounts of crowd control (0.2s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
771Vayne
962Kassadin
Kassadin vastly out-sustains Vayne, healing and mitigating 191 more damage per minute. This massive durability gap means Kassadin can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Best Vayne Build Against Kassadin

Gunmetal Greaves is the optimal boots choice against Kassadin, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Kassadin are Blade of The Ruined King, Guinsoo's Rageblade and Stormrazor. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Kassadin. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Kassadin matchup.

Early Game vs Late Game

Early Game
Vayne
100.0%
+100.0% advantage
Vayne early game win rateVayne100.0%
Kassadin early game win rateKassadin0.0%
Late Game
Vayne
66.7%
+33.3% advantage
Vayne late game win rateVayne66.7%
Kassadin late game win rateKassadin33.3%

Vayne dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Kassadin. This lopsided early game means Vayne can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Vayne is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Kassadin. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.

Vayne holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Kassadin players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Vayne Runes Against Kassadin

Precision rune tree - Vayne primary runes vs KassadinPrecision
Lethal Tempo - best Vayne rune vs KassadinTriumph - best Vayne rune vs KassadinLegend: Alacrity - best Vayne rune vs KassadinCoup de Grace - best Vayne rune vs Kassadin
Resolve rune tree - Vayne secondary runes vs KassadinResolve
Conditioning - best Vayne rune vs KassadinOvergrowth - best Vayne rune vs Kassadin
100.0% WR

Running Precision primary with Resolve secondary allows Vayne to press their advantage against Kassadin, amplifying the strengths that make this a favorable matchup.


Vayne matchup data for League of Legends patch 26.11. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vayne matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
46.01%4766.078912,87544.3%47.4%
47.20%4476.079112,72545.4%48.6%
46.26%4285.779612,71544.9%47.3%
53.92%3956.085712,96853.2%54.6%
47.85%3726.289413,18946.8%48.6%
52.99%3516.284313,14252.5%53.4%
52.98%2856.390413,45646.2%58.8%
53.90%2696.387713,73748.2%58.0%
52.38%1895.988612,46846.1%58.2%
51.92%1566.591311,98950.0%53.4%
54.30%1516.185913,22758.5%51.2%
50.33%1516.180413,00743.8%55.2%
45.95%1485.978013,60345.3%46.3%
45.38%1306.177613,08138.2%50.7%
47.83%1156.481213,76538.5%52.6%
42.61%1156.178112,08234.0%49.2%
50.88%1145.886612,98941.2%58.7%
45.19%1046.489913,17548.7%43.1%
59.80%1026.585413,18963.5%56.0%
31.00%1005.563510,36011.1%47.3%
45.83%965.885713,16444.4%46.7%
50.53%956.31,12012,73751.6%50.0%
58.06%936.379613,00854.8%60.8%
44.09%935.862511,33042.4%45.0%
45.56%905.883011,35543.6%47.1%
45.98%876.385113,57237.9%50.0%
55.81%866.189910,74843.2%65.3%
55.95%846.21,29211,54651.4%59.2%
56.41%786.388313,43557.1%55.8%
54.84%625.981412,06158.3%52.6%
45.76%596.287712,77548.0%44.1%
51.92%526.091311,59248.1%56.0%
45.10%516.592112,14440.9%48.3%
52.00%506.087513,62147.8%55.6%
35.42%486.272110,98228.0%43.5%
58.33%486.198911,81064.0%52.2%
45.83%486.21,00510,83851.9%38.1%
50.00%466.297013,36447.4%51.9%
58.70%466.291413,67162.5%54.5%
54.55%446.287414,06357.1%53.3%
44.19%436.683913,74455.0%34.8%
26.19%425.987411,67823.5%28.0%
48.78%415.983611,64443.5%55.6%
52.50%405.683813,60737.5%56.3%
38.46%396.785410,96150.0%28.6%
41.03%396.07439,57128.6%55.6%
67.57%376.589811,52662.5%76.9%
45.95%375.683211,99840.0%50.0%
52.94%346.475912,24550.0%54.5%
52.94%346.41,05111,47452.6%53.3%
66.67%336.393813,52461.5%70.0%
48.48%336.478411,26950.0%46.1%
48.48%336.597913,30562.5%44.0%
40.63%325.382011,34442.1%38.5%
62.50%325.779613,16341.7%75.0%
40.63%326.267610,36931.6%53.9%
58.06%316.484912,13864.3%52.9%
53.33%305.685512,15255.6%52.4%
60.00%306.095312,30876.9%47.1%
43.33%306.664611,44137.5%50.0%
55.56%275.379211,00650.0%60.0%
48.15%276.283411,46543.8%54.5%
50.00%265.969311,80141.7%57.1%
50.00%266.171011,42146.1%53.9%
30.77%265.370011,00127.3%33.3%
50.00%265.883412,30154.5%46.7%
48.00%256.081612,91020.0%66.7%
44.00%256.475811,84450.0%38.5%
54.17%246.399112,32564.3%40.0%
45.83%246.085011,12557.1%30.0%
56.52%235.761010,29945.5%66.7%
45.45%226.573412,18438.5%55.6%
40.91%226.080612,81544.4%38.5%
42.11%196.292010,37245.5%37.5%
63.16%196.387012,58950.0%72.7%
42.11%195.881712,14257.1%33.3%
61.11%185.61,00813,43366.7%58.3%
62.50%166.188511,54762.5%62.5%
80.00%152.288517,36850.0%84.6%
53.33%156.498513,30150.0%54.5%
60.00%156.583311,24437.5%85.7%
46.67%156.687611,53050.0%42.9%
46.67%155.491613,99225.0%54.5%
42.86%146.482413,96675.0%30.0%
42.86%146.084113,4470.0%66.7%
53.85%136.584913,506100.0%33.3%
46.15%135.275011,57950.0%42.9%
66.67%125.61,02512,92880.0%57.1%
33.33%126.092711,90033.3%33.3%
54.55%115.61,00213,29850.0%57.1%
63.64%116.164210,20450.0%80.0%
54.55%112.982014,06866.7%40.0%
81.82%116.277512,783100.0%71.4%
54.55%113.484613,74333.3%62.5%
54.55%115.576111,64971.4%25.0%
45.45%115.69159,80875.0%28.6%
40.00%104.670811,73250.0%25.0%
60.00%105.782012,59750.0%62.5%
50.00%103.877113,23733.3%57.1%
40.00%105.592611,89340.0%40.0%
66.67%93.81,03913,79866.7%66.7%
33.33%96.11,07613,2730.0%50.0%
55.56%96.793013,145100.0%20.0%
33.33%96.085513,01833.3%33.3%
55.56%93.986012,86033.3%66.7%
50.00%85.887014,56550.0%50.0%
62.50%87.368411,84766.7%50.0%
50.00%83.288313,47975.0%25.0%
25.00%85.26909,10216.7%50.0%
37.50%85.85269,89450.0%25.0%
57.14%74.076010,75033.3%75.0%
71.43%73.674311,42580.0%50.0%
42.86%74.572311,69733.3%50.0%
28.57%74.567612,0460.0%40.0%
50.00%63.578115,0220.0%60.0%
33.33%66.882313,7790.0%50.0%
33.33%62.998912,89833.3%33.3%
66.67%65.91,00614,14350.0%75.0%
20.00%54.75778,99933.3%0.0%
40.00%52.161112,29050.0%0.0%
40.00%56.41,17614,5940.0%50.0%
80.00%56.21,02413,762100.0%66.7%
40.00%55.996213,2480.0%50.0%
40.00%56.06739,21850.0%0.0%
40.00%56.47269,89240.0%0.0%

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Vayne vs Kassadin - Frequently Asked Questions

How does Vayne do against Kassadin in League of Legends?

Vayne wins the Vayne vs Kassadin matchup with a 80.0% win rate compared to Kassadin's 20.0%, a 60.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.11.

How does Vayne do against Kassadin in the early game?

In the early game, Vayne has the advantage against Kassadin with a 100.0% win rate versus 0.0%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vayne do against Kassadin in the late game?

In the late game, Vayne takes over the Vayne vs Kassadin matchup with a 66.7% win rate compared to 33.3%. Vayne scales better into team fights and objective contests after 25 minutes.

Who wins the Vayne vs Kassadin matchup?

Vayne wins the matchup against Kassadin with a 80.0% win rate in League of Legends patch 26.11. The 60.0 percentage point advantage means Vayne is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Vayne build against Kassadin?

The best Vayne build against Kassadin includes Blade of The Ruined King, Guinsoo's Rageblade, Stormrazor with Gunmetal Greaves. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Vayne runes against Kassadin?

The best Vayne runes against Kassadin use the Precision primary tree with Resolve secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Kassadin matchup. See the full rune breakdown in the matchup comparison above.

Does Vayne counter Kassadin?

Yes, Vayne has a favorable matchup against Kassadin with a 80.0% win rate. Vayne strongly counters Kassadin in lane based on current patch 26.11 data.

How do I play Vayne against Kassadin?

When playing Vayne against Kassadin, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.