Leona - League of Legends Champion
Win Rate
49.4%
Pick Rate
4.0%

Leonavs Vayne

DTankSupport
Patch26.5
Matches469,660
LaneAll Lanes
TierAll Tiers
Last UpdatedMar 12, 2026
MethodologyData Methodology

Leona vs Vayne is a decisive matchup in LoL patch 26.5. Vayne wins with a 80.0% win rate (+60.0%) over Leona based on 5 games. Vayne holds the advantage in both the early and late game. Below you'll find the best Leona build, runes, laning stats, and strategies for the Leona vs Vayne matchup.

Leona Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Leona performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vayne - 20.0% win rateVayne(20.0%)
Leona - 20.0% win rate in this matchup
Leona
20.0% WR
VS
Vayne vs Leona matchup - 80.0% win rate
Vayne
80.0% WR

Who Wins the Leona vs Vayne Matchup?

Vayne wins the Leona vs Vayne matchup
Winner
Vayne
Matches: 5
20.0%
Win Rate
80.0%
3.0
CS / min
2.9
528
DMG / min
624
10,470
Gold / game
12,089
103
Heal / min
171
1,319
DMG Mitigated / min
311
1.9
CC / min
0.5
0.0%
Early Game WR
100.0%
33.3%
Late Game WR
66.7%

Leona vs Vayne Matchup Summary

The Leona vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Vayne wins with a 80.0% win rate compared to Leona's 20.0%, giving Vayne a 60.0 percentage point advantage. Vayne dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Leona players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Leona leads by 1.4s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne has a strong advantage in this matchup. Leona players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Vayne overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Leona vs Vayne Laning Phase Breakdown

Leona wins the laning phase against Vayne in League of Legends

Leona is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Leona holds advantages in farming, crowd control and sustain, making them the stronger laner in this matchup.

Farming
3.0Leona
2.9Vayne
Leona and Vayne farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
528Leona
624Vayne
Vayne heavily out-damages Leona by 95 DMG/min, dominating both short trades and all-in fights. Leona should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vayne's sustained damage advantage take over.
Economy
10,470Leona
12,089Vayne
Vayne generates a commanding 1,619 more gold per game than Leona. This substantial economic advantage means Vayne consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Leona should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.9Leona
0.5Vayne
Leona brings significantly more crowd control than Vayne, with 1.4 more seconds of CC per minute. This large utility gap makes Leona far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Vayne should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
1,422Leona
482Vayne
Leona vastly out-sustains Vayne, healing and mitigating 940 more damage per minute. This massive durability gap means Leona can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Best Leona Build Against Vayne

Plated Steelcaps is the optimal boots choice against Vayne, providing the mobility and stats Leona needs most in this matchup. The top-performing core items for Leona against Vayne are Frozen Heart, Thornmail and Sunfire Aegis. This combination gives Leona an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Leona vs Vayne matchup.

Early Game vs Late Game

Early Game
Vayne
100.0%
+100.0% advantage
Leona early game win rateLeona0.0%
Vayne early game win rateVayne100.0%
Late Game
Vayne
66.7%
+33.3% advantage
Leona late game win rateLeona33.3%
Vayne late game win rateVayne66.7%

Vayne dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Leona. This lopsided early game means Vayne can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Vayne is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Leona. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.

Vayne holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Leona players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Leona Runes Against Vayne

Resolve rune tree - Leona primary runes vs VayneResolve
Aftershock - best Leona rune vs VayneFont of Life - best Leona rune vs VayneBone Plating - best Leona rune vs VayneUnflinching - best Leona rune vs Vayne
Inspiration rune tree - Leona secondary runes vs VayneInspiration
Biscuit Delivery - best Leona rune vs VayneCosmic Insight - best Leona rune vs Vayne
33.3% WR

The Resolve and Inspiration rune setup gives Leona the best tools to compete against Vayne in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Leona matchup data for League of Legends patch 26.5. The table below shows Leona's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Leona build, runes, laning stats, and early vs late game analysis for that specific matchup.

Leona matchup win rates and stats in League of Legends patch 26.5
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
49.78%2311.13788,57351.0%48.8%
45.41%2291.13928,79550.0%41.0%
45.37%2161.13598,93444.4%46.0%
49.19%1851.13478,77641.3%55.2%
45.98%1741.13448,53250.6%41.8%
47.66%1281.13679,00150.0%45.8%
50.40%1251.13708,97749.1%51.4%
44.54%1191.13478,56253.6%36.5%
49.09%1101.14108,60354.0%45.0%
51.85%1081.13758,62352.4%51.1%
48.60%1071.03998,99544.2%52.7%
53.33%1051.03949,07354.7%51.9%
47.00%1001.03888,33550.0%44.2%
47.31%931.13669,48939.4%51.7%
56.52%921.13278,61063.8%48.9%
54.65%861.13548,89154.0%55.1%
50.59%851.13668,14052.1%48.6%
57.32%821.03958,67864.9%51.1%
46.91%811.04379,32751.5%43.8%
60.76%791.03799,33045.2%70.8%
47.30%741.04349,01345.2%48.8%
47.22%721.14059,75245.5%48.0%
55.38%651.04078,75660.0%51.4%
54.39%571.03508,31167.9%41.4%
44.64%561.13428,36646.4%42.9%
50.91%551.14048,77250.0%51.5%
37.74%531.14499,47645.8%31.0%
55.77%521.04009,42650.0%60.0%
60.00%501.03708,85656.5%63.0%
51.02%491.14039,32347.8%53.9%
55.56%451.13858,39362.1%43.8%
44.19%431.03648,24350.0%36.8%
29.27%411.04008,85322.2%34.8%
52.63%381.03729,12756.3%50.0%
65.52%291.14399,39270.0%63.2%
50.00%241.03989,57555.6%46.7%
50.00%221.04068,77040.0%58.3%
75.00%200.94059,11783.3%71.4%
50.00%181.23829,81466.7%41.7%
41.18%171.14779,36842.9%40.0%
53.33%150.93669,55066.7%44.4%
50.00%141.14069,22066.7%37.5%
41.67%121.44026,99771.4%0.0%
36.36%111.23448,70742.9%25.0%
27.27%111.23868,80420.0%33.3%
63.64%111.34139,92160.0%66.7%
50.00%101.23719,68575.0%33.3%
40.00%101.04639,6650.0%57.1%
66.67%91.24639,27583.3%33.3%
33.33%91.13948,39520.0%50.0%
87.50%80.84008,274100.0%80.0%
71.43%71.146310,757100.0%66.7%
42.86%71.03097,4490.0%60.0%
100.00%61.24278,758100.0%100.0%
50.00%61.24769,329100.0%0.0%
50.00%60.83578,23966.7%33.3%
50.00%61.139910,4270.0%60.0%
16.67%61.04229,6200.0%25.0%
20.00%53.052810,4700.0%33.3%
20.00%51.042510,0160.0%20.0%
20.00%51.046311,1800.0%20.0%
40.00%51.13707,00850.0%0.0%

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Leona vs Vayne - Frequently Asked Questions

How does Leona do against Vayne in League of Legends?

Vayne wins the Leona vs Vayne matchup with a 80.0% win rate compared to Leona's 20.0%, a 60.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.5.

How does Leona do against Vayne in the early game?

In the early game, Vayne has the advantage against Leona with a 100.0% win rate versus 0.0%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Leona do against Vayne in the late game?

In the late game, Vayne takes over the Leona vs Vayne matchup with a 66.7% win rate compared to 33.3%. Vayne scales better into team fights and objective contests after 25 minutes.

Who wins the Leona vs Vayne matchup?

Vayne wins the matchup against Leona with a 80.0% win rate in League of Legends patch 26.5. The 60.0 percentage point advantage means Vayne is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Leona build against Vayne?

The best Leona build against Vayne includes Frozen Heart, Thornmail, Sunfire Aegis with Plated Steelcaps. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Leona runes against Vayne?

The best Leona runes against Vayne use the Resolve primary tree with Inspiration secondary. This rune setup achieves a 33.3% win rate in the Leona vs Vayne matchup. See the full rune breakdown in the matchup comparison above.

Does Leona counter Vayne?

No, Leona struggles against Vayne with only a 20.0% win rate. Vayne has the advantage in this matchup. Leona players should focus on safe farming and avoiding extended trades to minimize Vayne's lead.

How do I play Leona against Vayne?

When playing Leona against Vayne, play cautiously and avoid Vayne's power spikes. Look for jungle assistance and team-dependent plays since Vayne has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.