Vayne - League of Legends Champion
Win Rate
48.6%
Pick Rate
5.5%

Vaynevs Leona

FMarksmanAssassin
Patch26.5
Matches469,660
LaneAll Lanes
TierAll Tiers
Last UpdatedMar 12, 2026
MethodologyData Methodology

Vayne vs Leona is a decisive matchup in LoL patch 26.5. Vayne wins with a 80.0% win rate (+60.0%) over Leona based on 5 games. Vayne holds the advantage in both the early and late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Leona matchup.

Vayne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Leona - 80.0% win rateLeona(80.0%)
Vayne - 80.0% win rate in this matchup
Vayne
80.0% WR
VS
Leona vs Vayne matchup - 20.0% win rate
Leona
20.0% WR

Who Wins the Vayne vs Leona Matchup?

Vayne wins the Vayne vs Leona matchup
Winner
Vayne
Matches: 5
80.0%
Win Rate
20.0%
2.9
CS / min
3.0
624
DMG / min
528
12,089
Gold / game
10,470
171
Heal / min
103
311
DMG Mitigated / min
1,319
0.5
CC / min
1.9
100.0%
Early Game WR
0.0%
66.7%
Late Game WR
33.3%

Vayne vs Leona Matchup Summary

The Vayne vs Leona matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Vayne wins with a 80.0% win rate compared to Leona's 20.0%, giving Vayne a 60.0 percentage point advantage. Vayne dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Leona players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Leona leads by 1.4s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne players can confidently pick into Leona and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Leona away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vayne vs Leona Laning Phase Breakdown

Leona wins the laning phase against Vayne in League of Legends

Leona is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Leona holds advantages in farming, crowd control and sustain, making them the stronger laner in this matchup.

Farming
2.9Vayne
3.0Leona
Vayne and Leona farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
624Vayne
528Leona
Vayne heavily out-damages Leona by 95 DMG/min, dominating both short trades and all-in fights. Leona should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vayne's sustained damage advantage take over.
Economy
12,089Vayne
10,470Leona
Vayne generates a commanding 1,619 more gold per game than Leona. This substantial economic advantage means Vayne consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Leona should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.5Vayne
1.9Leona
Leona brings significantly more crowd control than Vayne, with 1.4 more seconds of CC per minute. This large utility gap makes Leona far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Vayne should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
482Vayne
1,422Leona
Leona vastly out-sustains Vayne, healing and mitigating 940 more damage per minute. This massive durability gap means Leona can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Best Vayne Build Against Leona

Berserker's Greaves is the optimal boots choice against Leona, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Leona are Kraken Slayer, Blade of The Ruined King and Guinsoo's Rageblade. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Leona. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Leona matchup.

Early Game vs Late Game

Early Game
Vayne
100.0%
+100.0% advantage
Vayne early game win rateVayne100.0%
Leona early game win rateLeona0.0%
Late Game
Vayne
66.7%
+33.3% advantage
Vayne late game win rateVayne66.7%
Leona late game win rateLeona33.3%

Vayne dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Leona. This lopsided early game means Vayne can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Vayne is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Leona. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.

Vayne holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Leona players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Vayne Runes Against Leona

Precision rune tree - Vayne primary runes vs LeonaPrecision
Press the Attack - best Vayne rune vs LeonaTriumph - best Vayne rune vs LeonaLegend: Bloodline - best Vayne rune vs LeonaCut Down - best Vayne rune vs Leona
Domination rune tree - Vayne secondary runes vs LeonaDomination
Taste of Blood - best Vayne rune vs LeonaUltimate Hunter - best Vayne rune vs Leona
100.0% WR

Running Precision primary with Domination secondary allows Vayne to press their advantage against Leona, amplifying the strengths that make this a favorable matchup.


Vayne matchup data for League of Legends patch 26.5. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vayne matchup win rates and stats in League of Legends patch 26.5
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
45.19%3436.081313,33642.9%47.1%
50.32%3126.386513,63654.4%46.6%
44.63%2985.883113,48143.4%45.6%
46.62%2966.185113,46647.8%45.9%
55.98%2346.394614,23250.9%60.3%
45.37%2055.982213,19041.3%48.7%
57.37%1906.293413,51955.0%59.6%
50.27%1856.492614,20251.3%49.5%
52.17%1386.087713,59861.1%46.4%
44.44%1356.084712,23336.6%53.1%
48.51%1346.188012,68251.9%43.4%
51.49%1015.874111,57147.3%56.5%
40.00%1006.088214,17237.1%41.5%
47.47%996.483712,99350.0%44.9%
56.38%946.794411,82157.5%55.3%
44.09%936.290713,01535.7%51.0%
52.22%906.391113,74951.1%53.3%
40.48%846.085112,97631.7%48.8%
50.72%695.776712,52155.9%45.7%
52.63%576.283813,31450.0%54.5%
34.62%526.395913,63831.8%36.7%
57.69%526.196012,54854.5%60.0%
41.18%516.285312,27948.5%27.8%
50.00%505.568411,26038.1%58.6%
43.75%486.51,01312,48033.3%51.9%
40.43%475.784412,83729.4%46.7%
65.22%466.296712,43861.1%67.9%
52.17%466.21,01012,67847.8%56.5%
48.89%456.699912,37159.1%39.1%
52.27%446.51,03313,51152.0%52.6%
45.45%446.079814,09853.3%41.4%
46.15%396.389214,12553.3%41.7%
42.11%386.479012,60133.3%50.0%
63.16%386.383113,35747.4%79.0%
67.57%376.396314,55771.4%65.2%
45.95%376.31,37311,58353.3%40.9%
52.78%366.31,10412,11147.1%57.9%
44.12%345.763811,24831.6%60.0%
39.39%336.273410,82136.8%42.9%
53.13%326.596512,72560.0%47.1%
56.25%325.585813,96854.5%57.1%
58.06%316.490711,97952.9%64.3%
58.62%296.296911,37443.8%76.9%
46.43%286.991912,21946.7%46.1%
64.00%256.31,02314,55170.0%60.0%
48.00%255.896712,69330.0%60.0%
60.00%255.31,14214,27050.0%64.7%
34.78%236.188611,70225.0%45.5%
52.17%236.399912,43053.9%50.0%
34.78%236.579510,27233.3%37.5%
39.13%236.294012,38540.0%38.5%
59.09%226.11,09515,40466.7%53.9%
50.00%226.084811,68446.1%55.6%
52.38%216.789513,74242.9%57.1%
42.86%216.41,11512,73066.7%25.0%
42.86%215.780511,35554.5%30.0%
42.86%216.299313,73433.3%46.7%
30.00%206.278811,78912.5%41.7%
45.00%206.080413,90042.9%46.1%
50.00%206.792713,34650.0%50.0%
42.11%196.780412,20155.6%30.0%
44.44%186.282014,48466.7%33.3%
52.94%176.282312,99350.0%55.6%
47.06%176.287711,43133.3%62.5%
58.82%176.690312,86266.7%50.0%
18.75%166.169211,33920.0%16.7%
66.67%156.799012,94866.7%66.7%
40.00%155.71,02813,5380.0%54.5%
50.00%146.591410,06354.5%33.3%
50.00%146.066211,40566.7%37.5%
78.57%146.71,12013,87875.0%80.0%
64.29%145.51,19413,06842.9%85.7%
61.54%137.089912,63783.3%42.9%
61.54%136.577612,07957.1%66.7%
25.00%126.575113,23414.3%40.0%
63.64%115.888913,83040.0%83.3%
50.00%105.91,06512,9710.0%71.4%
50.00%105.172010,51642.9%66.7%
33.33%96.581813,63450.0%28.6%
55.56%94.01,17914,12666.7%50.0%
33.33%96.179712,20050.0%20.0%
66.67%93.888213,55066.7%66.7%
66.67%97.087613,88860.0%75.0%
44.44%96.292911,87540.0%50.0%
37.50%82.762111,38833.3%40.0%
25.00%85.797814,065100.0%0.0%
37.50%86.187413,9500.0%42.9%
62.50%86.51,01112,94550.0%75.0%
62.50%86.968412,92466.7%60.0%
75.00%86.11,04414,72475.0%75.0%
28.57%75.191010,88733.3%25.0%
57.14%75.36167,27560.0%50.0%
14.29%76.467711,3330.0%50.0%
33.33%66.61,06311,61020.0%100.0%
50.00%66.090813,57850.0%50.0%
33.33%64.290910,53933.3%0.0%
50.00%65.91,00111,45050.0%50.0%
16.67%66.366411,6560.0%50.0%
83.33%63.794012,48466.7%100.0%
50.00%65.776410,47450.0%50.0%
40.00%52.985514,3690.0%40.0%
60.00%57.394411,6170.0%100.0%
60.00%52.58059,80066.7%50.0%
40.00%56.086014,4070.0%100.0%
80.00%52.962412,089100.0%66.7%
40.00%53.392311,80150.0%33.3%
20.00%55.978210,08333.3%0.0%
60.00%56.41,41715,830100.0%50.0%
40.00%53.377114,1990.0%50.0%
20.00%55.471911,3500.0%33.3%
80.00%56.986810,38280.0%0.0%

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Vayne vs Leona - Frequently Asked Questions

How does Vayne do against Leona in League of Legends?

Vayne wins the Vayne vs Leona matchup with a 80.0% win rate compared to Leona's 20.0%, a 60.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.5.

How does Vayne do against Leona in the early game?

In the early game, Vayne has the advantage against Leona with a 100.0% win rate versus 0.0%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vayne do against Leona in the late game?

In the late game, Vayne takes over the Vayne vs Leona matchup with a 66.7% win rate compared to 33.3%. Vayne scales better into team fights and objective contests after 25 minutes.

Who wins the Vayne vs Leona matchup?

Vayne wins the matchup against Leona with a 80.0% win rate in League of Legends patch 26.5. The 60.0 percentage point advantage means Vayne is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Vayne build against Leona?

The best Vayne build against Leona includes Kraken Slayer, Blade of The Ruined King, Guinsoo's Rageblade with Berserker's Greaves. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Vayne runes against Leona?

The best Vayne runes against Leona use the Precision primary tree with Domination secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Leona matchup. See the full rune breakdown in the matchup comparison above.

Does Vayne counter Leona?

Yes, Vayne has a favorable matchup against Leona with a 80.0% win rate. Vayne strongly counters Leona in lane based on current patch 26.5 data.

How do I play Vayne against Leona?

When playing Vayne against Leona, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.