
Vaynevs Leona
Vayne vs Leona is a decisive matchup in LoL patch 26.10. Leona wins with a 60.0% win rate (+20.0%) over Vayne based on 5 games. Vayne wins the early laning phase while Leona scales better into the late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Leona matchup.
Vayne Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Vayne vs Leona Matchup?

Vayne vs Leona Matchup Summary
The Vayne vs Leona matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Leona wins with a 60.0% win rate compared to Vayne's 40.0%, giving Leona a 20.0 percentage point advantage. Game phase dynamics play a critical role here: Vayne controls the early laning stage, but Leona outscales as the game goes longer. The matchup shifts dramatically depending on game length — Vayne needs to press advantages before Leona reaches their power spikes, while Leona should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Leona leads by 1.1s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Leona has a strong advantage in this matchup. Vayne players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Leona overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Vayne vs Leona Laning Phase Breakdown
Vayne is favored during the laning phase against Leona, winning 3 out of 5 key stat categories. Vayne holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.
Early Game vs Late Game
Vayne dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Leona. This lopsided early game means Vayne can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Leona is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Vayne. Extended games heavily favor Leona, whose kit and scaling make them a dominant force in team fights and objective control.
This matchup features a dramatic power shift: Vayne must aggressively press their early advantage and close out the game before Leona reaches their scaling breakpoints. If Leona survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.
Best Vayne Runes Against Leona
The Precision and Resolve rune setup gives Vayne the best tools to compete against Leona in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Vayne matchup data for League of Legends patch 26.10. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 45.05% | 839 | 6.2 | 880 | 13,450 | 47.4% | 43.5% | |
| 48.17% | 656 | 6.0 | 776 | 12,946 | 46.3% | 49.6% | |
| 46.27% | 644 | 6.1 | 818 | 13,004 | 45.0% | 47.3% | |
| 51.71% | 526 | 6.3 | 857 | 13,182 | 49.8% | 53.4% | |
| 51.79% | 502 | 6.0 | 852 | 13,384 | 47.8% | 54.5% | |
| 48.63% | 475 | 5.8 | 762 | 12,867 | 48.4% | 48.9% | |
| 56.31% | 396 | 6.3 | 894 | 13,342 | 53.5% | 58.4% | |
| 60.68% | 295 | 6.2 | 907 | 13,988 | 58.6% | 62.4% | |
| 55.30% | 217 | 5.9 | 834 | 13,239 | 57.3% | 53.7% | |
| 55.24% | 210 | 6.0 | 858 | 12,409 | 51.9% | 58.5% | |
| 49.05% | 210 | 6.0 | 802 | 12,588 | 51.0% | 47.4% | |
| 54.45% | 191 | 6.0 | 820 | 13,001 | 50.0% | 57.8% | |
| 54.84% | 186 | 6.5 | 998 | 12,804 | 52.8% | 56.1% | |
| 58.43% | 166 | 6.3 | 831 | 13,464 | 50.7% | 64.8% | |
| 53.05% | 164 | 6.0 | 816 | 12,587 | 39.1% | 63.2% | |
| 38.36% | 159 | 5.7 | 621 | 11,507 | 25.8% | 46.4% | |
| 48.10% | 158 | 6.1 | 844 | 14,003 | 53.6% | 45.1% | |
| 48.67% | 150 | 6.5 | 887 | 13,411 | 44.9% | 51.9% | |
| 49.33% | 150 | 6.0 | 852 | 12,819 | 50.7% | 48.1% | |
| 58.62% | 145 | 6.1 | 928 | 12,284 | 58.2% | 58.9% | |
| 33.08% | 130 | 5.5 | 571 | 10,017 | 27.9% | 37.7% | |
| 53.54% | 127 | 6.3 | 900 | 12,107 | 47.4% | 58.6% | |
| 48.76% | 121 | 6.2 | 802 | 13,061 | 49.1% | 48.5% | |
| 42.50% | 120 | 6.0 | 809 | 12,870 | 36.5% | 47.1% | |
| 47.06% | 119 | 6.3 | 940 | 12,931 | 47.3% | 46.9% | |
| 50.43% | 117 | 6.3 | 878 | 13,670 | 56.8% | 46.6% | |
| 46.09% | 115 | 5.8 | 938 | 11,440 | 38.8% | 51.5% | |
| 58.18% | 110 | 6.1 | 890 | 12,694 | 55.1% | 60.7% | |
| 49.46% | 93 | 6.5 | 1,131 | 13,262 | 44.7% | 52.7% | |
| 50.57% | 87 | 6.4 | 1,338 | 12,803 | 45.2% | 53.6% | |
| 51.81% | 83 | 5.7 | 929 | 12,252 | 48.5% | 54.0% | |
| 46.75% | 77 | 6.3 | 895 | 11,399 | 44.4% | 48.8% | |
| 47.37% | 76 | 5.9 | 763 | 10,988 | 32.4% | 59.5% | |
| 42.11% | 76 | 6.0 | 947 | 11,088 | 34.2% | 50.0% | |
| 55.71% | 70 | 6.2 | 890 | 13,332 | 62.5% | 52.2% | |
| 46.97% | 66 | 6.1 | 930 | 11,943 | 48.6% | 45.2% | |
| 51.52% | 66 | 6.7 | 875 | 11,849 | 48.6% | 54.8% | |
| 63.64% | 66 | 6.5 | 934 | 12,622 | 56.0% | 68.3% | |
| 58.46% | 65 | 6.4 | 1,008 | 12,304 | 68.8% | 48.5% | |
| 48.44% | 64 | 6.3 | 760 | 11,916 | 50.0% | 47.1% | |
| 55.93% | 59 | 6.1 | 849 | 12,506 | 47.6% | 60.5% | |
| 51.72% | 58 | 5.8 | 838 | 13,896 | 52.6% | 51.3% | |
| 48.21% | 56 | 5.8 | 1,025 | 12,308 | 59.1% | 41.2% | |
| 47.27% | 55 | 6.2 | 799 | 12,670 | 50.0% | 44.0% | |
| 50.00% | 52 | 5.4 | 816 | 11,249 | 43.5% | 55.2% | |
| 51.92% | 52 | 6.2 | 939 | 14,362 | 55.0% | 50.0% | |
| 49.02% | 51 | 6.0 | 851 | 11,083 | 43.3% | 57.1% | |
| 55.10% | 49 | 6.1 | 966 | 12,054 | 66.7% | 46.4% | |
| 59.57% | 47 | 6.0 | 1,012 | 11,998 | 71.4% | 50.0% | |
| 46.67% | 45 | 6.1 | 883 | 13,204 | 47.4% | 46.1% | |
| 54.55% | 44 | 6.1 | 876 | 14,137 | 77.8% | 48.6% | |
| 47.73% | 44 | 6.3 | 966 | 11,320 | 47.6% | 47.8% | |
| 37.21% | 43 | 5.8 | 791 | 12,953 | 30.8% | 40.0% | |
| 54.76% | 42 | 6.0 | 852 | 13,525 | 47.4% | 60.9% | |
| 47.62% | 42 | 5.8 | 789 | 11,955 | 53.3% | 44.4% | |
| 52.50% | 40 | 5.8 | 800 | 12,315 | 66.7% | 40.9% | |
| 37.50% | 40 | 6.0 | 737 | 11,780 | 25.0% | 50.0% | |
| 52.50% | 40 | 6.3 | 877 | 13,266 | 50.0% | 55.0% | |
| 33.33% | 39 | 6.2 | 928 | 12,078 | 29.4% | 36.4% | |
| 51.28% | 39 | 5.8 | 922 | 10,345 | 52.6% | 50.0% | |
| 62.16% | 37 | 6.5 | 749 | 12,659 | 64.3% | 60.9% | |
| 54.05% | 37 | 6.2 | 868 | 11,488 | 50.0% | 57.9% | |
| 51.35% | 37 | 5.7 | 733 | 10,951 | 43.8% | 57.1% | |
| 58.33% | 36 | 6.1 | 855 | 12,984 | 42.9% | 68.2% | |
| 48.57% | 35 | 5.0 | 866 | 12,820 | 41.7% | 52.2% | |
| 57.14% | 35 | 5.2 | 876 | 12,469 | 64.7% | 50.0% | |
| 39.39% | 33 | 6.2 | 926 | 12,703 | 38.9% | 40.0% | |
| 59.38% | 32 | 6.5 | 983 | 11,197 | 35.3% | 86.7% | |
| 41.94% | 31 | 5.8 | 823 | 13,002 | 50.0% | 36.8% | |
| 45.16% | 31 | 6.1 | 874 | 14,107 | 36.4% | 50.0% | |
| 50.00% | 30 | 6.0 | 852 | 11,615 | 42.9% | 56.3% | |
| 43.33% | 30 | 6.2 | 720 | 12,954 | 9.1% | 63.2% | |
| 51.72% | 29 | 5.7 | 860 | 10,775 | 64.7% | 33.3% | |
| 42.86% | 28 | 5.4 | 815 | 10,853 | 50.0% | 30.0% | |
| 53.57% | 28 | 6.6 | 928 | 12,009 | 42.9% | 64.3% | |
| 51.85% | 27 | 6.1 | 974 | 11,861 | 50.0% | 53.9% | |
| 44.44% | 27 | 6.5 | 891 | 12,161 | 50.0% | 41.2% | |
| 46.15% | 26 | 5.0 | 887 | 12,374 | 62.5% | 38.9% | |
| 50.00% | 24 | 5.6 | 788 | 11,010 | 45.5% | 53.9% | |
| 45.45% | 22 | 4.8 | 748 | 13,218 | 50.0% | 42.9% | |
| 54.55% | 22 | 6.4 | 936 | 12,880 | 62.5% | 50.0% | |
| 57.14% | 21 | 6.1 | 798 | 13,041 | 33.3% | 75.0% | |
| 57.14% | 21 | 6.3 | 870 | 12,434 | 83.3% | 46.7% | |
| 33.33% | 21 | 6.2 | 749 | 11,377 | 36.4% | 30.0% | |
| 52.63% | 19 | 6.3 | 971 | 12,604 | 33.3% | 61.5% | |
| 52.63% | 19 | 6.0 | 753 | 12,145 | 55.6% | 50.0% | |
| 61.11% | 18 | 6.0 | 679 | 14,021 | 50.0% | 66.7% | |
| 66.67% | 18 | 6.0 | 889 | 12,772 | 54.5% | 85.7% | |
| 41.18% | 17 | 6.3 | 868 | 11,576 | 42.9% | 40.0% | |
| 43.75% | 16 | 6.7 | 825 | 13,174 | 14.3% | 66.7% | |
| 40.00% | 15 | 5.1 | 695 | 10,508 | 37.5% | 42.9% | |
| 40.00% | 15 | 2.5 | 933 | 13,534 | 42.9% | 37.5% | |
| 60.00% | 15 | 6.3 | 826 | 11,698 | 71.4% | 50.0% | |
| 60.00% | 15 | 6.1 | 695 | 11,652 | 50.0% | 66.7% | |
| 46.67% | 15 | 6.5 | 752 | 12,249 | 28.6% | 62.5% | |
| 50.00% | 14 | 2.4 | 608 | 10,726 | 40.0% | 75.0% | |
| 50.00% | 14 | 6.3 | 886 | 12,182 | 42.9% | 57.1% | |
| 46.15% | 13 | 4.3 | 999 | 12,496 | 25.0% | 55.6% | |
| 46.15% | 13 | 4.6 | 684 | 10,460 | 33.3% | 57.1% | |
| 41.67% | 12 | 4.6 | 659 | 12,641 | 100.0% | 36.4% | |
| 58.33% | 12 | 5.8 | 879 | 12,782 | 25.0% | 75.0% | |
| 50.00% | 12 | 5.9 | 867 | 13,254 | 33.3% | 55.6% | |
| 45.45% | 11 | 3.8 | 639 | 11,593 | 42.9% | 50.0% | |
| 45.45% | 11 | 4.8 | 1,088 | 10,505 | 40.0% | 50.0% | |
| 36.36% | 11 | 2.8 | 671 | 12,891 | 33.3% | 37.5% | |
| 30.00% | 10 | 4.1 | 705 | 12,871 | 50.0% | 16.7% | |
| 30.00% | 10 | 6.3 | 916 | 12,407 | 66.7% | 14.3% | |
| 30.00% | 10 | 2.1 | 762 | 12,593 | 33.3% | 28.6% | |
| 44.44% | 9 | 1.9 | 726 | 13,909 | 33.3% | 50.0% | |
| 22.22% | 9 | 5.7 | 1,064 | 11,677 | 25.0% | 20.0% | |
| 77.78% | 9 | 2.4 | 1,028 | 15,988 | 100.0% | 66.7% | |
| 37.50% | 8 | 3.7 | 691 | 11,475 | 33.3% | 40.0% | |
| 37.50% | 8 | 3.5 | 933 | 13,788 | 0.0% | 50.0% | |
| 50.00% | 8 | 6.0 | 841 | 12,323 | 0.0% | 66.7% | |
| 50.00% | 8 | 6.4 | 823 | 10,015 | 66.7% | 40.0% | |
| 28.57% | 7 | 4.8 | 695 | 12,602 | 0.0% | 40.0% | |
| 57.14% | 7 | 3.7 | 1,106 | 16,343 | 100.0% | 40.0% | |
| 57.14% | 7 | 6.5 | 931 | 10,444 | 50.0% | 66.7% | |
| 28.57% | 7 | 6.6 | 964 | 11,298 | 40.0% | 0.0% | |
| 42.86% | 7 | 4.4 | 702 | 13,833 | 33.3% | 50.0% | |
| 33.33% | 6 | 5.1 | 852 | 12,323 | 0.0% | 50.0% | |
| 50.00% | 6 | 4.0 | 854 | 12,424 | 50.0% | 50.0% | |
| 66.67% | 6 | 5.4 | 747 | 12,282 | 50.0% | 75.0% | |
| 83.33% | 6 | 5.2 | 843 | 14,256 | 50.0% | 100.0% | |
| 50.00% | 6 | 5.0 | 807 | 12,120 | 66.7% | 33.3% | |
| 50.00% | 6 | 1.1 | 703 | 15,491 | 100.0% | 40.0% | |
| 20.00% | 5 | 3.2 | 942 | 16,416 | 0.0% | 20.0% | |
| 40.00% | 5 | 3.8 | 659 | 10,470 | 66.7% | 0.0% | |
| 60.00% | 5 | 2.1 | 932 | 14,040 | 100.0% | 33.3% | |
| 40.00% | 5 | 4.3 | 789 | 13,959 | 100.0% | 0.0% | |
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Vayne vs Leona - Frequently Asked Questions
How does Vayne do against Leona in League of Legends?
Leona wins the Vayne vs Leona matchup with a 60.0% win rate compared to Vayne's 40.0%, a 20.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.10.
How does Vayne do against Leona in the early game?
In the early game, Vayne has the advantage against Leona with a 66.7% win rate versus 33.3%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Vayne do against Leona in the late game?
In the late game, Leona takes over the Vayne vs Leona matchup with a 100.0% win rate compared to 0.0%. Leona scales better into team fights and objective contests after 25 minutes.
Who wins the Vayne vs Leona matchup?
Leona wins the matchup against Vayne with a 60.0% win rate in League of Legends patch 26.10. The 20.0 percentage point advantage means Leona is significantly favored in this lane matchup based on 5 games analyzed.
What is the best Vayne build against Leona?
The best Vayne build against Leona includes optimized core items. Check the matchup breakdown above for the full item path and build order.
What are the best Vayne runes against Leona?
The best Vayne runes against Leona use the Precision primary tree with Resolve secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Leona matchup. See the full rune breakdown in the matchup comparison above.
Does Vayne counter Leona?
No, Vayne struggles against Leona with only a 40.0% win rate. Leona has the advantage in this matchup. Vayne players should focus on safe farming and avoiding extended trades to minimize Leona's lead.
How do I play Vayne against Leona?
When playing Vayne against Leona, play cautiously and avoid Leona's power spikes. Look for jungle assistance and team-dependent plays since Leona has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.