Vayne - League of Legends Champion
Win Rate
49.5%
Pick Rate
5.4%

Vaynevs Leona

CMarksmanAssassin
Patch26.10
Matches2,222,046
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 21, 2026
MethodologyData Methodology

Vayne vs Leona is a decisive matchup in LoL patch 26.10. Leona wins with a 60.0% win rate (+20.0%) over Vayne based on 5 games. Vayne wins the early laning phase while Leona scales better into the late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Leona matchup.

Vayne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Leona - 40.0% win rateLeona(40.0%)
Vayne - 40.0% win rate in this matchup
Vayne
40.0% WR
VS
Leona vs Vayne matchup - 60.0% win rate
Leona
60.0% WR

Who Wins the Vayne vs Leona Matchup?

Leona wins the Vayne vs Leona matchup
Winner
Leona
Matches: 5
40.0%
Win Rate
60.0%
3.8
CS / min
2.6
659
DMG / min
424
10,470
Gold / game
9,152
157
Heal / min
102
437
DMG Mitigated / min
887
0.4
CC / min
1.6
66.7%
Early Game WR
33.3%
0.0%
Late Game WR
100.0%

Vayne vs Leona Matchup Summary

The Vayne vs Leona matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Leona wins with a 60.0% win rate compared to Vayne's 40.0%, giving Leona a 20.0 percentage point advantage. Game phase dynamics play a critical role here: Vayne controls the early laning stage, but Leona outscales as the game goes longer. The matchup shifts dramatically depending on game length — Vayne needs to press advantages before Leona reaches their power spikes, while Leona should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Leona leads by 1.1s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Leona has a strong advantage in this matchup. Vayne players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Leona overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vayne vs Leona Laning Phase Breakdown

Vayne wins the laning phase against Leona in League of Legends

Vayne is favored during the laning phase against Leona, winning 3 out of 5 key stat categories. Vayne holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
3.8Vayne
2.6Leona
Vayne significantly out-farms Leona by 1.3 CS per minute, accumulating an estimated 19 CS lead by mid game. This substantial farming gap gives Vayne a major gold advantage and earlier item completions. Leona players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
659Vayne
424Leona
Vayne heavily out-damages Leona by 235 DMG/min, dominating both short trades and all-in fights. Leona should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vayne's sustained damage advantage take over.
Economy
10,470Vayne
9,152Leona
Vayne generates a commanding 1,318 more gold per game than Leona. This substantial economic advantage means Vayne consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Leona should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.4Vayne
1.6Leona
Leona brings significantly more crowd control than Vayne, with 1.1 more seconds of CC per minute. This large utility gap makes Leona far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Vayne should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
594Vayne
989Leona
Leona vastly out-sustains Vayne, healing and mitigating 395 more damage per minute. This massive durability gap means Leona can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Early Game vs Late Game

Early Game
Vayne
66.7%
+33.3% advantage
Vayne early game win rateVayne66.7%
Leona early game win rateLeona33.3%
Late Game
Leona
100.0%
+100.0% advantage
Vayne late game win rateVayne0.0%
Leona late game win rateLeona100.0%

Vayne dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Leona. This lopsided early game means Vayne can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Leona is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Vayne. Extended games heavily favor Leona, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Vayne must aggressively press their early advantage and close out the game before Leona reaches their scaling breakpoints. If Leona survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Vayne Runes Against Leona

Precision rune tree - Vayne primary runes vs LeonaPrecision
Press the Attack - best Vayne rune vs LeonaTriumph - best Vayne rune vs LeonaLegend: Alacrity - best Vayne rune vs LeonaCoup de Grace - best Vayne rune vs Leona
Resolve rune tree - Vayne secondary runes vs LeonaResolve
Conditioning - best Vayne rune vs LeonaOvergrowth - best Vayne rune vs Leona
100.0% WR

The Precision and Resolve rune setup gives Vayne the best tools to compete against Leona in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Vayne matchup data for League of Legends patch 26.10. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vayne matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
45.05%8396.288013,45047.4%43.5%
48.17%6566.077612,94646.3%49.6%
46.27%6446.181813,00445.0%47.3%
51.71%5266.385713,18249.8%53.4%
51.79%5026.085213,38447.8%54.5%
48.63%4755.876212,86748.4%48.9%
56.31%3966.389413,34253.5%58.4%
60.68%2956.290713,98858.6%62.4%
55.30%2175.983413,23957.3%53.7%
55.24%2106.085812,40951.9%58.5%
49.05%2106.080212,58851.0%47.4%
54.45%1916.082013,00150.0%57.8%
54.84%1866.599812,80452.8%56.1%
58.43%1666.383113,46450.7%64.8%
53.05%1646.081612,58739.1%63.2%
38.36%1595.762111,50725.8%46.4%
48.10%1586.184414,00353.6%45.1%
48.67%1506.588713,41144.9%51.9%
49.33%1506.085212,81950.7%48.1%
58.62%1456.192812,28458.2%58.9%
33.08%1305.557110,01727.9%37.7%
53.54%1276.390012,10747.4%58.6%
48.76%1216.280213,06149.1%48.5%
42.50%1206.080912,87036.5%47.1%
47.06%1196.394012,93147.3%46.9%
50.43%1176.387813,67056.8%46.6%
46.09%1155.893811,44038.8%51.5%
58.18%1106.189012,69455.1%60.7%
49.46%936.51,13113,26244.7%52.7%
50.57%876.41,33812,80345.2%53.6%
51.81%835.792912,25248.5%54.0%
46.75%776.389511,39944.4%48.8%
47.37%765.976310,98832.4%59.5%
42.11%766.094711,08834.2%50.0%
55.71%706.289013,33262.5%52.2%
46.97%666.193011,94348.6%45.2%
51.52%666.787511,84948.6%54.8%
63.64%666.593412,62256.0%68.3%
58.46%656.41,00812,30468.8%48.5%
48.44%646.376011,91650.0%47.1%
55.93%596.184912,50647.6%60.5%
51.72%585.883813,89652.6%51.3%
48.21%565.81,02512,30859.1%41.2%
47.27%556.279912,67050.0%44.0%
50.00%525.481611,24943.5%55.2%
51.92%526.293914,36255.0%50.0%
49.02%516.085111,08343.3%57.1%
55.10%496.196612,05466.7%46.4%
59.57%476.01,01211,99871.4%50.0%
46.67%456.188313,20447.4%46.1%
54.55%446.187614,13777.8%48.6%
47.73%446.396611,32047.6%47.8%
37.21%435.879112,95330.8%40.0%
54.76%426.085213,52547.4%60.9%
47.62%425.878911,95553.3%44.4%
52.50%405.880012,31566.7%40.9%
37.50%406.073711,78025.0%50.0%
52.50%406.387713,26650.0%55.0%
33.33%396.292812,07829.4%36.4%
51.28%395.892210,34552.6%50.0%
62.16%376.574912,65964.3%60.9%
54.05%376.286811,48850.0%57.9%
51.35%375.773310,95143.8%57.1%
58.33%366.185512,98442.9%68.2%
48.57%355.086612,82041.7%52.2%
57.14%355.287612,46964.7%50.0%
39.39%336.292612,70338.9%40.0%
59.38%326.598311,19735.3%86.7%
41.94%315.882313,00250.0%36.8%
45.16%316.187414,10736.4%50.0%
50.00%306.085211,61542.9%56.3%
43.33%306.272012,9549.1%63.2%
51.72%295.786010,77564.7%33.3%
42.86%285.481510,85350.0%30.0%
53.57%286.692812,00942.9%64.3%
51.85%276.197411,86150.0%53.9%
44.44%276.589112,16150.0%41.2%
46.15%265.088712,37462.5%38.9%
50.00%245.678811,01045.5%53.9%
45.45%224.874813,21850.0%42.9%
54.55%226.493612,88062.5%50.0%
57.14%216.179813,04133.3%75.0%
57.14%216.387012,43483.3%46.7%
33.33%216.274911,37736.4%30.0%
52.63%196.397112,60433.3%61.5%
52.63%196.075312,14555.6%50.0%
61.11%186.067914,02150.0%66.7%
66.67%186.088912,77254.5%85.7%
41.18%176.386811,57642.9%40.0%
43.75%166.782513,17414.3%66.7%
40.00%155.169510,50837.5%42.9%
40.00%152.593313,53442.9%37.5%
60.00%156.382611,69871.4%50.0%
60.00%156.169511,65250.0%66.7%
46.67%156.575212,24928.6%62.5%
50.00%142.460810,72640.0%75.0%
50.00%146.388612,18242.9%57.1%
46.15%134.399912,49625.0%55.6%
46.15%134.668410,46033.3%57.1%
41.67%124.665912,641100.0%36.4%
58.33%125.887912,78225.0%75.0%
50.00%125.986713,25433.3%55.6%
45.45%113.863911,59342.9%50.0%
45.45%114.81,08810,50540.0%50.0%
36.36%112.867112,89133.3%37.5%
30.00%104.170512,87150.0%16.7%
30.00%106.391612,40766.7%14.3%
30.00%102.176212,59333.3%28.6%
44.44%91.972613,90933.3%50.0%
22.22%95.71,06411,67725.0%20.0%
77.78%92.41,02815,988100.0%66.7%
37.50%83.769111,47533.3%40.0%
37.50%83.593313,7880.0%50.0%
50.00%86.084112,3230.0%66.7%
50.00%86.482310,01566.7%40.0%
28.57%74.869512,6020.0%40.0%
57.14%73.71,10616,343100.0%40.0%
57.14%76.593110,44450.0%66.7%
28.57%76.696411,29840.0%0.0%
42.86%74.470213,83333.3%50.0%
33.33%65.185212,3230.0%50.0%
50.00%64.085412,42450.0%50.0%
66.67%65.474712,28250.0%75.0%
83.33%65.284314,25650.0%100.0%
50.00%65.080712,12066.7%33.3%
50.00%61.170315,491100.0%40.0%
20.00%53.294216,4160.0%20.0%
40.00%53.865910,47066.7%0.0%
60.00%52.193214,040100.0%33.3%
40.00%54.378913,959100.0%0.0%

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Vayne vs Leona - Frequently Asked Questions

How does Vayne do against Leona in League of Legends?

Leona wins the Vayne vs Leona matchup with a 60.0% win rate compared to Vayne's 40.0%, a 20.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.10.

How does Vayne do against Leona in the early game?

In the early game, Vayne has the advantage against Leona with a 66.7% win rate versus 33.3%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vayne do against Leona in the late game?

In the late game, Leona takes over the Vayne vs Leona matchup with a 100.0% win rate compared to 0.0%. Leona scales better into team fights and objective contests after 25 minutes.

Who wins the Vayne vs Leona matchup?

Leona wins the matchup against Vayne with a 60.0% win rate in League of Legends patch 26.10. The 20.0 percentage point advantage means Leona is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Vayne build against Leona?

The best Vayne build against Leona includes optimized core items. Check the matchup breakdown above for the full item path and build order.

What are the best Vayne runes against Leona?

The best Vayne runes against Leona use the Precision primary tree with Resolve secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Leona matchup. See the full rune breakdown in the matchup comparison above.

Does Vayne counter Leona?

No, Vayne struggles against Leona with only a 40.0% win rate. Leona has the advantage in this matchup. Vayne players should focus on safe farming and avoiding extended trades to minimize Leona's lead.

How do I play Vayne against Leona?

When playing Vayne against Leona, play cautiously and avoid Leona's power spikes. Look for jungle assistance and team-dependent plays since Leona has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.