Rek'Saivs Vayne
Rek'Sai vs Vayne is a decisive matchup in LoL patch 26.10. Vayne wins with a 60.0% win rate (+20.0%) over Rek'Sai based on 5 games. Rek'Sai wins the early laning phase while Vayne scales better into the late game. Below you'll find the best Rek'Sai build, runes, laning stats, and strategies for the Rek'Sai vs Vayne matchup.
Rek'Sai Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Rek'Sai performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Rek'Sai vs Vayne Matchup?
Rek'Sai vs Vayne Matchup Summary
The Rek'Sai vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Vayne wins with a 60.0% win rate compared to Rek'Sai's 40.0%, giving Vayne a 20.0 percentage point advantage. Game phase dynamics play a critical role here: Rek'Sai controls the early laning stage, but Vayne outscales as the game goes longer. The matchup shifts dramatically depending on game length — Rek'Sai needs to press advantages before Vayne reaches their power spikes, while Vayne should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Rek'Sai leads by 1,152 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne has a strong advantage in this matchup. Rek'Sai players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Vayne overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Rek'Sai vs Vayne Laning Phase Breakdown
Rek'Sai is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Rek'Sai holds advantages in damage, crowd control and sustain, making them the stronger laner in this matchup.
Best Rek'Sai Build Against Vayne
Boots of Swiftness is the optimal boots choice against Vayne, providing the mobility and stats Rek'Sai needs most in this matchup. The top-performing core items for Rek'Sai against Vayne are Eclipse, Titanic Hydra and Mortal Reminder. This combination gives Rek'Sai an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Rek'Sai vs Vayne matchup.
Early Game vs Late Game
Rek'Sai0.0%
Vayne0.0%Rek'Sai40.0%Vayne60.0%The early game (first 15 minutes) is a toss-up between Rek'Sai and Vayne, with Rek'Sai holding a razor-thin 0.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.
Vayne is far superior in the late game (25+ minutes), boasting a 60.0% win rate — 20.0 points above Rek'Sai. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.
The power dynamics shift as the game progresses — Rek'Sai has the edge early, but Vayne gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.
Best Rek'Sai Runes Against Vayne
Domination
Sorcery
The Domination and Sorcery rune setup gives Rek'Sai the best tools to compete against Vayne in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Rek'Sai matchup data for League of Legends patch 26.10. The table below shows Rek'Sai's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Rek'Sai build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 48.81% | 85 | 1.0 | 662 | 13,014 | 53.1% | 46.1% | |
| 52.38% | 84 | 0.8 | 637 | 12,415 | 51.2% | 53.5% | |
| 52.63% | 76 | 0.7 | 581 | 11,575 | 55.0% | 50.0% | |
| 47.37% | 76 | 0.8 | 650 | 12,361 | 48.8% | 45.7% | |
| 50.67% | 75 | 0.8 | 591 | 12,487 | 54.5% | 47.6% | |
| 49.25% | 67 | 0.8 | 651 | 12,696 | 42.3% | 53.7% | |
| 56.72% | 67 | 0.7 | 694 | 12,212 | 47.1% | 66.7% | |
| 53.45% | 58 | 0.7 | 638 | 12,202 | 58.6% | 48.3% | |
| 51.85% | 54 | 0.7 | 657 | 12,926 | 47.8% | 54.8% | |
| 30.19% | 53 | 0.9 | 633 | 12,518 | 41.7% | 20.7% | |
| 54.00% | 50 | 0.6 | 605 | 11,784 | 43.5% | 63.0% | |
| 41.30% | 46 | 1.0 | 743 | 12,183 | 42.9% | 40.0% | |
| 57.50% | 40 | 0.8 | 659 | 13,246 | 61.5% | 55.6% | |
| 43.59% | 39 | 0.9 | 741 | 12,917 | 50.0% | 40.7% | |
| 47.37% | 38 | 1.3 | 644 | 11,693 | 55.0% | 38.9% | |
| 45.95% | 37 | 0.8 | 641 | 11,786 | 40.9% | 53.3% | |
| 61.11% | 36 | 1.0 | 639 | 12,937 | 60.0% | 61.9% | |
| 57.14% | 35 | 0.8 | 693 | 12,276 | 64.3% | 52.4% | |
| 62.50% | 32 | 0.8 | 754 | 13,365 | 54.5% | 66.7% | |
| 43.33% | 30 | 0.7 | 608 | 12,336 | 30.8% | 52.9% | |
| 58.62% | 29 | 0.8 | 675 | 13,197 | 58.3% | 58.8% | |
| 50.00% | 28 | 1.0 | 562 | 11,785 | 60.0% | 44.4% | |
| 48.15% | 27 | 0.8 | 716 | 12,785 | 50.0% | 46.7% | |
| 30.77% | 26 | 0.8 | 634 | 12,261 | 35.7% | 25.0% | |
| 50.00% | 26 | 0.9 | 672 | 13,229 | 30.0% | 62.5% | |
| 53.85% | 26 | 1.2 | 701 | 12,397 | 62.5% | 50.0% | |
| 36.36% | 22 | 0.8 | 647 | 13,334 | 37.5% | 35.7% | |
| 80.95% | 21 | 0.8 | 643 | 12,314 | 90.9% | 70.0% | |
| 57.89% | 19 | 1.1 | 666 | 11,941 | 33.3% | 69.2% | |
| 26.32% | 19 | 1.0 | 704 | 11,966 | 12.5% | 36.4% | |
| 73.68% | 19 | 1.0 | 737 | 12,901 | 81.8% | 62.5% | |
| 44.44% | 18 | 0.7 | 732 | 13,513 | 50.0% | 41.7% | |
| 58.82% | 17 | 0.6 | 670 | 11,822 | 57.1% | 60.0% | |
| 41.18% | 17 | 0.6 | 593 | 13,327 | 20.0% | 50.0% | |
| 31.25% | 16 | 2.9 | 582 | 11,853 | 55.6% | 0.0% | |
| 56.25% | 16 | 2.8 | 667 | 10,322 | 62.5% | 50.0% | |
| 33.33% | 15 | 2.4 | 781 | 12,272 | 44.4% | 16.7% | |
| 60.00% | 15 | 0.9 | 575 | 11,849 | 50.0% | 71.4% | |
| 46.67% | 15 | 2.5 | 977 | 13,744 | 40.0% | 50.0% | |
| 53.33% | 15 | 0.8 | 656 | 11,957 | 50.0% | 55.6% | |
| 64.29% | 14 | 0.7 | 682 | 13,571 | 80.0% | 55.6% | |
| 46.15% | 13 | 1.0 | 715 | 12,142 | 40.0% | 50.0% | |
| 53.85% | 13 | 2.7 | 910 | 13,673 | 66.7% | 50.0% | |
| 61.54% | 13 | 1.1 | 828 | 13,600 | 60.0% | 62.5% | |
| 75.00% | 12 | 0.8 | 635 | 13,154 | 71.4% | 80.0% | |
| 41.67% | 12 | 0.7 | 603 | 13,046 | 25.0% | 50.0% | |
| 20.00% | 10 | 1.5 | 603 | 10,592 | 0.0% | 28.6% | |
| 70.00% | 10 | 1.8 | 590 | 11,991 | 80.0% | 60.0% | |
| 70.00% | 10 | 0.7 | 654 | 13,771 | 50.0% | 83.3% | |
| 40.00% | 10 | 2.8 | 486 | 9,094 | 40.0% | 40.0% | |
| 62.50% | 8 | 1.8 | 726 | 14,457 | 50.0% | 66.7% | |
| 25.00% | 8 | 2.3 | 561 | 10,994 | 50.0% | 0.0% | |
| 37.50% | 8 | 1.0 | 551 | 10,285 | 40.0% | 33.3% | |
| 14.29% | 7 | 5.7 | 1,123 | 14,191 | 0.0% | 16.7% | |
| 71.43% | 7 | 1.0 | 401 | 10,131 | 33.3% | 100.0% | |
| 42.86% | 7 | 0.8 | 492 | 12,355 | 0.0% | 60.0% | |
| 71.43% | 7 | 1.5 | 653 | 12,970 | 100.0% | 33.3% | |
| 28.57% | 7 | 1.9 | 781 | 13,948 | 0.0% | 50.0% | |
| 33.33% | 6 | 3.4 | 684 | 12,268 | 33.3% | 33.3% | |
| 33.33% | 6 | 5.9 | 683 | 9,277 | 33.3% | 33.3% | |
| 66.67% | 6 | 1.0 | 705 | 13,277 | 0.0% | 80.0% | |
| 66.67% | 6 | 1.4 | 614 | 10,223 | 66.7% | 66.7% | |
| 50.00% | 6 | 0.8 | 657 | 12,944 | 66.7% | 33.3% | |
| 16.67% | 6 | 0.5 | 438 | 8,523 | 0.0% | 50.0% | |
| 66.67% | 6 | 1.2 | 562 | 7,316 | 66.7% | 0.0% | |
| 60.00% | 5 | 5.2 | 767 | 9,628 | 75.0% | 0.0% | |
| 40.00% | 5 | 3.7 | 886 | 12,912 | 0.0% | 40.0% | |
| 60.00% | 5 | 5.3 | 961 | 12,955 | 100.0% | 33.3% | |
| 20.00% | 5 | 2.7 | 787 | 12,383 | 0.0% | 33.3% | |
| 0.00% | 5 | 2.2 | 771 | 14,662 | 0.0% | 0.0% | |
| 40.00% | 5 | 2.3 | 846 | 12,781 | 33.3% | 50.0% | |
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Rek'Sai vs Vayne - Frequently Asked Questions
How does Rek'Sai do against Vayne in League of Legends?
Vayne wins the Rek'Sai vs Vayne matchup with a 60.0% win rate compared to Rek'Sai's 40.0%, a 20.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.10.
How does Rek'Sai do against Vayne in the early game?
In the early game, Rek'Sai has the advantage against Vayne with a 0.0% win rate versus 0.0%. Rek'Sai players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Rek'Sai do against Vayne in the late game?
In the late game, Vayne takes over the Rek'Sai vs Vayne matchup with a 60.0% win rate compared to 40.0%. Vayne scales better into team fights and objective contests after 25 minutes.
Who wins the Rek'Sai vs Vayne matchup?
Vayne wins the matchup against Rek'Sai with a 60.0% win rate in League of Legends patch 26.10. The 20.0 percentage point advantage means Vayne is significantly favored in this lane matchup based on 5 games analyzed.
What is the best Rek'Sai build against Vayne?
The best Rek'Sai build against Vayne includes Eclipse, Titanic Hydra, Mortal Reminder with Boots of Swiftness. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Rek'Sai runes against Vayne?
The best Rek'Sai runes against Vayne use the Domination primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Rek'Sai vs Vayne matchup. See the full rune breakdown in the matchup comparison above.
Does Rek'Sai counter Vayne?
No, Rek'Sai struggles against Vayne with only a 40.0% win rate. Vayne has the advantage in this matchup. Rek'Sai players should focus on safe farming and avoiding extended trades to minimize Vayne's lead.
How do I play Rek'Sai against Vayne?
When playing Rek'Sai against Vayne, play cautiously and avoid Vayne's power spikes. Look for jungle assistance and team-dependent plays since Vayne has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.