
Annie Runes
The top Annie runes in LoL patch 25.21 are Glacial Augment, Cash Back, Biscuit Delivery, Cosmic Insight for Annie's primary runes. Annie's runes in his secondary tree best utilizes Font of Life and Revitalize. These Annie rune choices provide the best Annie rune build for ranked.


Pyromania
After casting 4 spells, Annie's next offensive spell will stun the target.
Annie begins the game and respawns with Pyromania available.

Disintegrate
Annie hurls a Mana infused fireball, dealing damage and refunding the Mana cost if it destroys the target.
Cost:- 60/
- 65/
- 70/
- 75/
- 80
Cooldown:- 4
Range:- 625


Incinerate
Annie casts a blazing cone of fire, dealing damage to all enemies in the area.
Cost:- 70/
- 75/
- 80/
- 85/
- 90
Cooldown:- 7
Range:- 600


Molten Shield
Grants Annie or an ally a shield, a burst of Move Speed, and damages enemies who strike her with attacks or spells.
Cost:- 60/
- 65/
- 70/
- 75/
- 80
Cooldown:- 12/
- 12/
- 11/
- 11/
- 10
Range:- 800


Summon: Tibbers
Annie wills her bear Tibbers to life, dealing damage to units in the area. Tibbers can attack and also burns enemies that stand near him.
Cost:- 100
Cooldown:- 130/
- 115/
- 100
Range:- 600
- Mage,
- Support
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Annie Runes
Primary Tree
InspirationAnnie Runes - Alternative
Primary Tree
Sorcery
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