
Caitlyn Runes
The top Caitlyn runes in LoL patch 25.21 are Press the Attack, Triumph, Legend: Bloodline, Coup de Grace for Caitlyn's primary runes. Caitlyn's runes in his secondary tree best utilizes Transcendence and Gathering Storm. These Caitlyn rune choices provide the best Caitlyn rune build for ranked.


Headshot
Every few basic attacks, or against a target she has trapped or netted, Caitlyn will fire a headshot dealing bonus damage that scales with her critical strike chance. On trapped or netted targets, Caitlyn's Headshot attack range is doubled.


Piltover Peacemaker
Caitlyn revs up her rifle for 1 second to unleash a penetrating shot that deals physical damage (deals less damage to subsequent targets).
Cost:- 55/
- 60/
- 65/
- 70/
- 75
Cooldown:- 10/
- 9/
- 8/
- 7/
- 6
Range:- 1250


Yordle Snap Trap
Caitlyn sets a trap that, when sprung, reveals and immobilizes the enemy champion for 1.5 seconds, granting Caitlyn an empowered Headshot.
Cost:- 20
Cooldown:- 1
Range:- 800


90 Caliber Net
Caitlyn fires a heavy net to slow her target. The recoil knocks Caitlyn back.
Cost:- 75
Cooldown:- 16/
- 14/
- 12/
- 10/
- 8
Range:- 750


Ace in the Hole
Caitlyn takes time to line up the perfect shot, dealing massive damage to a single target at a huge range. Enemy champions can intercept the bullet for their ally.
Cost:- 100
Cooldown:- 90
Range:- 3500
- Marksman
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Caitlyn Runes
Primary Tree
PrecisionCaitlyn Runes - Alternative
Primary Tree
Domination
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