Karthus Counters

The best Karthus counters in League of Legends patch 25.21 are Zed, MasterYi, Caitlyn, Briar, Jax. The best Karthus counter is Zed, with Karthus having only a 33.33% win rate in this matchup. Secondary patch 25.21 Karthus counter choices are MonkeyKing, Kayn, Talon, Lillia, LeeSin. Below are the top Karthus counters and matchups alongside their win rates.

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  Death Defied

  Upon dying, Karthus enters a spirit form that allows him to continue casting spells.

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  Lay Waste

  Karthus unleashes a delayed blast at a location, dealing damage to nearby enemies. Deals increased damage to isolated enemies.

  Cost:

  • 20/
  • 25/
  • 30/
  • 35/
  • 40

  Cooldown:

  • 0

  Range:

  • 875
• 

  

  Wall of Pain

  Karthus creates a passable screen of leeching energy. Any enemy units that walk through the screen have their Move Speed and Magic Resist reduced for a period.

  Cost:

  • 70

  Cooldown:

  • 15

  Range:

  • 1000
• 

  

  Defile

  Karthus passively steals energy from his victims, gaining Mana on each kill. Alternatively, Karthus can surround himself in the souls of his prey, dealing damage to nearby enemies, but quickly draining his own Mana.

  Cost:

  • 30/
  • 42/
  • 54/
  • 66/
  • 78

  Cooldown:

  • 1

  Range:

  • 550
• 

  

  Requiem

  After channeling for 3 seconds, Karthus deals damage to all enemy champions.

  Cost:

  • 100

  Cooldown:

  • 200/
  • 180/
  • 160

  Range:

  • 10000