Caitlyn - League of Legends Champion
Win Rate
49.0%
Pick Rate
9.5%

Caitlynvs Lissandra

DMarksman
Patch26.10
Matches1,361,747
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 19, 2026
MethodologyData Methodology

Caitlyn vs Lissandra is a decisive matchup in LoL patch 26.10. Caitlyn wins with a 60.0% win rate (+20.0%) over Lissandra based on 5 games. Lissandra wins the early laning phase while Caitlyn scales better into the late game. Below you'll find the best Caitlyn build, runes, laning stats, and strategies for the Caitlyn vs Lissandra matchup.

Caitlyn Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Caitlyn performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Lissandra - 60.0% win rateLissandra(60.0%)
Caitlyn - 60.0% win rate in this matchup
Caitlyn
60.0% WR
VS
Lissandra vs Caitlyn matchup - 40.0% win rate
Lissandra
40.0% WR

Who Wins the Caitlyn vs Lissandra Matchup?

Caitlyn wins the Caitlyn vs Lissandra matchup
Winner
Caitlyn
Matches: 5
60.0%
Win Rate
40.0%
7.3
CS / min
7.0
991
DMG / min
623
12,598
Gold / game
9,888
178
Heal / min
131
394
DMG Mitigated / min
413
0.7
CC / min
1.4
33.3%
Early Game WR
66.7%
100.0%
Late Game WR
0.0%

Caitlyn vs Lissandra Matchup Summary

The Caitlyn vs Lissandra matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Caitlyn wins with a 60.0% win rate compared to Lissandra's 40.0%, giving Caitlyn a 20.0 percentage point advantage. Game phase dynamics play a critical role here: Lissandra controls the early laning stage, but Caitlyn outscales as the game goes longer. The matchup shifts dramatically depending on game length — Lissandra needs to press advantages before Caitlyn reaches their power spikes, while Caitlyn should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Lissandra leads by 0.7s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Caitlyn players can confidently pick into Lissandra and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Lissandra away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Caitlyn vs Lissandra Laning Phase Breakdown

Caitlyn wins the laning phase against Lissandra in League of Legends

Caitlyn is favored during the laning phase against Lissandra, winning 4 out of 5 key stat categories. Caitlyn holds advantages in farming, damage, gold income and sustain, making them the stronger laner in this matchup.

Farming
7.3Caitlyn
7.0Lissandra
Caitlyn edges out Lissandra by 0.3 CS per minute — a moderate farming advantage that adds up to roughly 5 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Caitlyn.
Damage
991Caitlyn
623Lissandra
Caitlyn heavily out-damages Lissandra by 369 DMG/min, dominating both short trades and all-in fights. Lissandra should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Caitlyn's sustained damage advantage take over.
Economy
12,598Caitlyn
9,888Lissandra
Caitlyn generates a commanding 2,710 more gold per game than Lissandra. This substantial economic advantage means Caitlyn consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Lissandra should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.7Caitlyn
1.4Lissandra
Lissandra provides 0.7 seconds more crowd control per minute than Caitlyn, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Lissandra coordinate with their jungler and control the pace of skirmishes.
Sustain
572Caitlyn
544Lissandra
Caitlyn and Lissandra have comparable sustain profiles, with only 27 HP/min separating their healing and damage mitigation. Neither champion can out-attrition the other in lane, so trades will be decided by burst potential and ability usage rather than sustain.

Best Caitlyn Build Against Lissandra

Gunmetal Greaves is the optimal boots choice against Lissandra, providing the mobility and stats Caitlyn needs most in this matchup. The top-performing core items for Caitlyn against Lissandra are The Collector, Bloodthirster and Lord Dominik's Regards. This combination gives Caitlyn an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Lissandra. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Caitlyn vs Lissandra matchup.

Early Game vs Late Game

Early Game
Lissandra
66.7%
+33.3% advantage
Caitlyn early game win rateCaitlyn33.3%
Lissandra early game win rateLissandra66.7%
Late Game
Caitlyn
100.0%
+100.0% advantage
Caitlyn late game win rateCaitlyn100.0%
Lissandra late game win rateLissandra0.0%

Lissandra dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Caitlyn. This lopsided early game means Lissandra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Caitlyn is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Lissandra. Extended games heavily favor Caitlyn, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Lissandra must aggressively press their early advantage and close out the game before Caitlyn reaches their scaling breakpoints. If Caitlyn survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Caitlyn Runes Against Lissandra

Inspiration rune tree - Caitlyn primary runes vs LissandraInspiration
First Strike - best Caitlyn rune vs LissandraMagical Footwear - best Caitlyn rune vs LissandraBiscuit Delivery - best Caitlyn rune vs LissandraCosmic Insight - best Caitlyn rune vs Lissandra
Sorcery rune tree - Caitlyn secondary runes vs LissandraSorcery
Absolute Focus - best Caitlyn rune vs LissandraGathering Storm - best Caitlyn rune vs Lissandra
100.0% WR

Running Inspiration primary with Sorcery secondary allows Caitlyn to press their advantage against Lissandra, amplifying the strengths that make this a favorable matchup.


Caitlyn matchup data for League of Legends patch 26.10. The table below shows Caitlyn's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Caitlyn build, runes, laning stats, and early vs late game analysis for that specific matchup.

Caitlyn matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
46.00%2,4396.991513,34347.9%44.7%
48.70%1,9616.885513,01649.0%48.5%
47.88%1,5546.582913,12549.9%46.5%
47.15%1,5426.986413,26048.1%46.4%
47.65%1,4676.884013,08344.4%49.9%
53.85%1,1576.988013,11951.4%55.8%
52.15%6736.890213,36953.5%51.2%
54.94%6177.090513,60953.2%56.3%
52.75%5106.788113,22752.6%52.9%
50.89%5056.684813,07253.9%48.6%
51.64%4576.887612,82953.6%49.8%
51.98%4546.989813,43848.2%54.9%
52.21%4086.788913,13251.1%53.2%
51.87%3746.990013,53148.7%54.2%
51.39%3616.785113,40946.6%55.3%
51.71%3506.984413,10352.2%51.3%
54.76%3477.088412,92858.2%50.6%
47.08%3087.287413,31653.8%42.0%
50.00%2986.986513,67050.4%49.7%
43.57%2806.882513,31943.2%43.8%
52.77%2357.092713,45849.0%55.6%
43.24%1857.077913,37933.9%48.0%
48.39%1556.679213,39450.0%47.4%
48.25%1436.690513,46342.4%53.3%
41.35%1336.886413,55743.9%39.5%
53.03%1327.191112,95459.1%47.0%
46.83%1266.390712,83038.0%52.6%
55.45%1106.678612,89853.9%56.9%
44.04%1096.981913,35847.7%41.5%
52.78%1087.086513,15455.6%50.0%
43.75%967.082113,66341.0%45.6%
34.07%916.678413,67416.7%42.6%
41.18%856.570012,13237.8%43.8%
54.93%716.889114,02043.5%60.4%
48.44%646.795614,18232.0%59.0%
52.83%536.31,07912,69630.8%74.1%
50.00%526.974112,62940.0%56.3%
46.94%496.874712,29638.1%53.6%
57.45%477.41,01012,56961.8%46.1%
40.91%446.877712,63438.9%42.3%
38.10%427.397614,98938.5%37.9%
42.86%286.992013,58827.3%52.9%
40.00%257.084912,05037.5%44.4%
54.17%247.075313,24937.5%62.5%
68.18%226.893913,89172.7%63.6%
40.00%207.174212,65520.0%60.0%
60.00%206.688715,03960.0%60.0%
52.63%196.781411,85450.0%57.1%
33.33%187.069813,44644.4%22.2%
58.82%176.91,08715,73283.3%45.5%
62.50%166.690515,05850.0%70.0%
46.67%157.277012,50433.3%66.7%
60.00%157.084813,34271.4%50.0%
35.71%146.591414,64666.7%27.3%
84.62%137.01,15813,42287.5%80.0%
38.46%137.071911,96950.0%20.0%
66.67%126.61,17115,94250.0%70.0%
41.67%126.867012,17433.3%44.4%
8.33%126.481311,8810.0%12.5%
58.33%126.591212,89160.0%57.1%
63.64%117.190816,39666.7%62.5%
36.36%116.977310,29325.0%66.7%
60.00%106.179814,4960.0%75.0%
60.00%106.482612,18360.0%60.0%
50.00%106.21,17814,85633.3%57.1%
40.00%106.21,01911,01933.3%50.0%
50.00%106.91,00814,98966.7%42.9%
30.00%107.01,19612,48340.0%20.0%
40.00%106.382812,13860.0%20.0%
55.56%96.381812,66966.7%50.0%
44.44%95.987812,27860.0%25.0%
33.33%96.894012,40520.0%50.0%
44.44%97.192811,90433.3%66.7%
37.50%85.767410,35840.0%33.3%
75.00%86.386814,05175.0%75.0%
62.50%85.580112,44025.0%100.0%
42.86%76.389713,648100.0%33.3%
42.86%76.576910,50425.0%66.7%
42.86%76.579614,81850.0%40.0%
16.67%63.051511,2090.0%25.0%
66.67%66.579814,77166.7%66.7%
50.00%66.472111,75950.0%50.0%
66.67%66.576711,59150.0%100.0%
50.00%65.881612,348100.0%0.0%
16.67%66.01,03514,7220.0%25.0%
33.33%66.71,04813,5150.0%50.0%
60.00%57.399112,59833.3%100.0%
40.00%56.77649,1810.0%100.0%
40.00%56.31,04915,58366.7%0.0%
20.00%57.289313,6840.0%50.0%
100.00%54.61,15017,8630.0%100.0%
20.00%55.71,03612,86650.0%0.0%

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Caitlyn vs Lissandra - Frequently Asked Questions

How does Caitlyn do against Lissandra in League of Legends?

Caitlyn wins the Caitlyn vs Lissandra matchup with a 60.0% win rate compared to Lissandra's 40.0%, a 20.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.10.

How does Caitlyn do against Lissandra in the early game?

In the early game, Lissandra has the advantage against Caitlyn with a 66.7% win rate versus 33.3%. Lissandra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Caitlyn do against Lissandra in the late game?

In the late game, Caitlyn takes over the Caitlyn vs Lissandra matchup with a 100.0% win rate compared to 0.0%. Caitlyn scales better into team fights and objective contests after 25 minutes.

Who wins the Caitlyn vs Lissandra matchup?

Caitlyn wins the matchup against Lissandra with a 60.0% win rate in League of Legends patch 26.10. The 20.0 percentage point advantage means Caitlyn is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Caitlyn build against Lissandra?

The best Caitlyn build against Lissandra includes The Collector, Bloodthirster, Lord Dominik's Regards with Gunmetal Greaves. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Caitlyn runes against Lissandra?

The best Caitlyn runes against Lissandra use the Inspiration primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Caitlyn vs Lissandra matchup. See the full rune breakdown in the matchup comparison above.

Does Caitlyn counter Lissandra?

Yes, Caitlyn has a favorable matchup against Lissandra with a 60.0% win rate. Caitlyn strongly counters Lissandra in lane based on current patch 26.10 data.

How do I play Caitlyn against Lissandra?

When playing Caitlyn against Lissandra, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Lissandra. Build the recommended items and runes for this specific matchup for the best results.