- Win Rate
- 49.7%
- Pick Rate
- 9.3%
- Ban Rate
- 32.9%
Caitlyn ADC Runes: Keystone & Shards
- Patch
- 26.21
- Games
- 18,490
- Lane
- Bot
- Tier
- All Tiers
- Last Updated
- Nov 3, 2026 UTC
- Author
- Dakota Chinnick
- Methodology
- Data Methodology
Best Bot Caitlyn runes for LoL Patch 26.21 - Lethal Tempo from the Precision tree with Inspiration secondary (58.1% WR, 1.2% pick rate). Caitlyn's optimal primary runes are Lethal Tempo, Presence of Mind, Legend: Bloodline, Cut Down. Secondary tree: Cash Back, Cosmic Insight.
Primary Tree
Precision
Lethal TempoAttacking an enemy champion grants you [6% Melee || 4% Ranged] Attack Speed for 6 seconds, up to 6. At max stacks, deal [9 - 30 Melee || 6 - 24 Ranged]
Presence of MindDamaging an enemy champion restores 6-50 (80% for ranged) mana or 6 energy.
Takedowns restore 15% of your maximum mana or energy.
Cooldown for damage restoration: 8s
Legend: BloodlineGain
Earn progress toward Legend stacks for every champion takedown, epic monster takedown, large monster kill, and minion kill.
Cut DownDeal 8% more damage to champions who have more than 60% health.
Cash BackGet 7.5% Gold back when you purchase Legendary Items.
Cosmic Insight+
+
Primary Tree
Precision
Lethal TempoAttacking an enemy champion grants you [6% Melee || 4% Ranged] Attack Speed for 6 seconds, up to 6. At max stacks, deal [9 - 30 Melee || 6 - 24 Ranged]
TriumphTakedowns restore 5% of your missing health, 2.5% of your max health, and grant an additional 20 gold.
'The most dangerous game brings the greatest glory.'
—Noxian Reckoner
Legend: BloodlineGain
Earn progress toward Legend stacks for every champion takedown, epic monster takedown, large monster kill, and minion kill.
Coup de GraceDeal 8% more damage to champions who have less than 40% health.
Absolute FocusWhile above 70% health, gain an
Grants 1.8 Attack Damage or 3 Ability Power at level 1.
Gathering StormEvery 10 min gain AP or AD,
10 min: + 8 AP or 5 AD
20 min: + 24 AP or 14 AD
30 min: + 48 AP or 29 AD
40 min: + 80 AP or 48 AD
50 min: + 120 AP or 72 AD
60 min: + 168 AP or 101 AD
etc...
Every Caitlyn Bot Keystone and Secondary Tree (Patch 26.21)
17,743 gamesCaitlyn Bot runs Lethal Tempo in 66% of games, with a 49.6% win rate. Sorcery is the usual secondary tree (88%). Standard stat shards: Attack Speed (offense), Adaptive Force (flex), Health Scaling (defense).
Keystones
| Rune | Players | Win Rate | Games |
|---|---|---|---|
| Lethal TempoMost played | 65.9% | 49.6% | 11,694 |
 First Strike | 17.1% | 50.4% | 3,034 |
 Fleet Footwork | 13.8% | 48.8% | 2,443 |
 Press the Attack | 1.2% | 49.1% | 214 |
 Dark Harvest | 1.0% | 48.6% | 179 |
Secondary trees
| Rune | Players | Win Rate | Games |
|---|---|---|---|
 SorceryMost played | 87.8% | 49.6% | 15,574 |
 Inspiration | 8.6% | 49.8% | 1,525 |
 Domination | 1.9% | 50.0% | 340 |
| Precision | 1.2% | 49.3% | 213 |
 Resolve | 0.5% | 46.1% | 89 |
Pick rate is the share of Caitlyn games in this lane that used the rune; options under 40 games are left out. A higher win rate on a rarely picked rune is usually a matchup-specific choice, not a general upgrade.
Caitlyn Minor Runes by Tree
Every minor rune Caitlyn players take, grouped by rune tree, with how often it is picked and how often it wins.
Sorcery
| Rune | Players | Win Rate | Games |
|---|---|---|---|
| Gathering StormMost played | 87.2% | 49.7% | 15,480 |
| Absolute Focus | 85.9% | 49.7% | 15,243 |
 Celerity | 0.6% | 44.3% | 106 |
 Manaflow Band | 0.6% | 41.2% | 102 |
 Axiom Arcanist | 0.6% | 38.8% | 98 |
 Nimbus Cloak | 0.5% | 55.8% | 95 |
Precision
| Rune | Players | Win Rate | Games |
|---|---|---|---|
| Legend: BloodlineMost played | 76.6% | 49.5% | 13,589 |
| Presence of Mind | 73.8% | 49.4% | 13,098 |
| Coup de Grace | 70.7% | 49.3% | 12,544 |
| Cut Down | 10.9% | 51.1% | 1,935 |
| Triumph | 7.5% | 50.2% | 1,326 |
 Legend: Alacrity | 4.9% | 49.8% | 878 |
Inspiration
| Rune | Players | Win Rate | Games |
|---|---|---|---|
| Cosmic InsightMost played | 20.1% | 49.8% | 3,564 |
 Biscuit Delivery | 17.5% | 50.4% | 3,098 |
 Magical Footwear | 16.9% | 49.8% | 2,999 |
| Cash Back | 8.5% | 51.0% | 1,517 |
 Triple Tonic | 4.6% | 50.0% | 812 |
Domination
| Rune | Players | Win Rate | Games |
|---|---|---|---|
 Ultimate HunterMost played | 1.7% | 44.4% | 293 |
 Cheap Shot | 1.5% | 46.9% | 258 |
 Treasure Hunter | 1.3% | 53.8% | 225 |
 Taste of Blood | 1.2% | 53.4% | 221 |
 Sudden Impact | 0.8% | 46.8% | 141 |
 Sixth Sense | 0.7% | 48.5% | 132 |
Caitlyn Stat Shards
Which stat shards Caitlyn players choose in each of the three shard rows, and the win rate of each.
| Rune | Players | Win Rate | Games |
|---|---|---|---|
 Adaptive Force (flex)Most played | 98.6% | 49.6% | 17,490 |
 Attack Speed (offense) | 97.5% | 49.6% | 17,307 |
 Health Scaling (defense) | 91.9% | 49.6% | 16,313 |
| Health (defense) | 5.8% | 50.7% | 1,036 |
 Tenacity and Slow Resist (defense) | 2.2% | 49.0% | 394 |
| Adaptive Force (offense) | 2.2% | 50.6% | 385 |
 Move Speed (flex) | 1.3% | 51.3% | 226 |
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Caitlyn Runes FAQ - Patch 26.21
What is the best keystone for Caitlyn Bot?
Lethal Tempo: Caitlyn Bot takes it in 66% of ranked games and wins 49.6% of 11,694 games. Alternatives: First Strike (17%, 50.4%), Fleet Footwork (14%, 48.8%).
What stat shards should Caitlyn take?
Most Caitlyn players take Attack Speed (offense), Adaptive Force (flex), Health Scaling (defense) — one from each shard row.
What are the best Caitlyn runes in patch 26.21?
The best Caitlyn runes in patch 26.21 use the Precision tree with Lethal Tempo, Presence of Mind, Legend: Bloodline, and Cut Down, and the Inspiration tree with Cash Back and Cosmic Insight. This rune setup achieves a 58.1% win rate with a 1.2% pick rate.
What is the win rate for Caitlyn's best rune page?
Caitlyn's best rune page has a 58.1% win rate in patch 26.21, which is +8.4% compared to Caitlyn's average win rate. This rune setup has a 1.2% pick rate among Caitlyn players.
What keystone should I use on Caitlyn?
Lethal Tempo from the Precision tree is the best keystone rune for Caitlyn in patch 26.21. This keystone synergizes well with Caitlyn's kit and provides a 58.1% win rate.
What is Caitlyn's primary rune tree?
Caitlyn's primary rune tree is Precision. The optimal Precision runes for Caitlyn are Lethal Tempo, Presence of Mind, Legend: Bloodline, and Cut Down, with Lethal Tempo being the keystone of choice.
What is Caitlyn's secondary rune tree?
Caitlyn's best secondary rune tree is Inspiration. The recommended Inspiration runes are Cash Back and Cosmic Insight, which complement Caitlyn's Precision primary tree.
What are alternative rune setups for Caitlyn?
An alternative Caitlyn rune setup uses Lethal Tempo from the Precision tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.
How popular are Caitlyn's runes?
Caitlyn's top rune page has a 1.2% pick rate in patch 26.21. This indicates that 1.2% of Caitlyn players use the Lethal Tempo setup with Precision and Inspiration trees.