Neeko - League of Legends Champion
Win Rate
47.6%
Pick Rate
1.7%

Neekovs Vayne

FMageSupport
Patch26.4
Matches1,089,240
LaneAll Lanes
TierAll Tiers
Last UpdatedMar 3, 2026
MethodologyData Methodology

Neeko vs Vayne is a decisive matchup in LoL patch 26.4. Vayne wins with a 71.4% win rate (+42.9%) over Neeko based on 7 games. Vayne wins the early laning phase while Neeko scales better into the late game. Below you'll find the best Neeko build, runes, laning stats, and strategies for the Neeko vs Vayne matchup.

Neeko Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Neeko performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vayne - 28.6% win rateVayne(28.6%)
Neeko - 28.6% win rate in this matchup
Neeko
28.6% WR
VS
Vayne vs Neeko matchup - 71.4% win rate
Vayne
71.4% WR

Who Wins the Neeko vs Vayne Matchup?

Vayne wins the Neeko vs Vayne matchup
Winner
Vayne
Matches: 7
28.6%
Win Rate
71.4%
4.7
CS / min
4.4
856
DMG / min
834
11,998
Gold / game
12,500
106
Heal / min
166
372
DMG Mitigated / min
407
1.6
CC / min
0.3
0.0%
Early Game WR
100.0%
50.0%
Late Game WR
50.0%

Neeko vs Vayne Matchup Summary

The Neeko vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 7 recent matches analyzed, Vayne wins with a 71.4% win rate compared to Neeko's 28.6%, giving Vayne a 42.9 percentage point advantage. Game phase dynamics play a critical role here: Vayne controls the early laning stage, but Neeko outscales as the game goes longer. The matchup shifts dramatically depending on game length — Vayne needs to press advantages before Neeko reaches their power spikes, while Neeko should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Neeko leads by 1.2s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne has a strong advantage in this matchup. Neeko players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Vayne overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Neeko vs Vayne Laning Phase Breakdown

Neeko wins the laning phase against Vayne in League of Legends

Neeko is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Neeko holds advantages in farming, damage and crowd control, making them the stronger laner in this matchup.

Farming
4.7Neeko
4.4Vayne
Neeko edges out Vayne by 0.3 CS per minute — a moderate farming advantage that adds up to roughly 5 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Neeko.
Damage
856Neeko
834Vayne
Damage output is virtually even between Neeko and Vayne, with only 22 DMG/min separating them. Fights in this matchup are decided more by ability timing and positioning than raw damage numbers, making mechanical skill the deciding factor in trades.
Economy
11,998Neeko
12,500Vayne
Vayne earns 502 more gold per game than Neeko, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Vayne slightly faster item completions.
Utility
1.6Neeko
0.3Vayne
Neeko brings significantly more crowd control than Vayne, with 1.2 more seconds of CC per minute. This large utility gap makes Neeko far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Vayne should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
478Neeko
573Vayne
Vayne heals and mitigates 95 more damage per minute than Neeko, providing moderate extra durability. This sustain edge allows Vayne to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Neeko.

Best Neeko Build Against Vayne

Sorcerer's Shoes is the optimal boots choice against Vayne, providing the mobility and stats Neeko needs most in this matchup. The top-performing core items for Neeko against Vayne are Luden's Echo, Stormsurge and Hextech Rocketbelt. This combination gives Neeko an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Neeko vs Vayne matchup.

Early Game vs Late Game

Early Game
Vayne
100.0%
+100.0% advantage
Neeko early game win rateNeeko0.0%
Vayne early game win rateVayne100.0%
Late Game
Neeko
50.0%
+0.0% advantage
Neeko late game win rateNeeko50.0%
Vayne late game win rateVayne50.0%

Vayne dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Neeko. This lopsided early game means Vayne can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Late game (25+ minutes) is equally balanced, with Neeko at 50.0% win rate — only 0.0 points ahead of Vayne. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.

The power dynamics shift as the game progresses — Vayne has the edge early, but Neeko gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Neeko Runes Against Vayne

Sorcery rune tree - Neeko primary runes vs VayneSorcery
Arcane Comet - best Neeko rune vs VayneManaflow Band - best Neeko rune vs VayneTranscendence - best Neeko rune vs VayneScorch - best Neeko rune vs Vayne
Domination rune tree - Neeko secondary runes vs VayneDomination
Cheap Shot - best Neeko rune vs VayneUltimate Hunter - best Neeko rune vs Vayne
100.0% WR

The Sorcery and Domination rune setup gives Neeko the best tools to compete against Vayne in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Neeko matchup data for League of Legends patch 26.4. The table below shows Neeko's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Neeko build, runes, laning stats, and early vs late game analysis for that specific matchup.

Neeko matchup win rates and stats in League of Legends patch 26.4
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
47.31%1891.66059,42250.0%44.8%
43.20%1712.25859,75544.4%42.0%
48.32%1501.66159,79550.0%47.0%
43.24%1111.85728,79742.3%44.1%
45.05%1111.85989,84247.6%43.5%
47.17%1071.76229,13853.7%40.4%
44.86%1071.66519,83548.9%41.7%
44.44%992.062010,06752.6%39.3%
42.53%872.267510,59245.2%41.1%
45.12%841.96689,79852.8%39.1%
44.30%801.65819,17444.4%44.2%
53.85%781.66809,99057.6%51.1%
50.00%771.76219,64248.6%51.2%
50.00%751.56419,36437.9%58.1%
54.79%731.765610,38550.0%57.5%
49.32%731.76139,22755.6%43.2%
45.83%722.47089,32941.9%48.8%
52.17%721.96369,94045.5%58.3%
52.94%682.360710,07844.4%58.5%
51.52%661.75218,24754.4%45.0%
44.62%651.65859,54039.3%48.6%
50.00%621.75679,19352.0%48.6%
46.43%565.780411,14660.9%36.4%
50.98%511.96299,64347.4%53.1%
47.83%472.65989,14530.4%65.2%
44.44%452.075610,51235.3%50.0%
44.44%453.06299,39842.9%45.8%
57.14%421.46018,65252.2%63.2%
58.54%415.776011,26158.8%58.3%
42.11%381.65879,06252.9%33.3%
43.24%375.077710,49050.0%36.8%
47.22%375.887111,67055.6%38.9%
34.29%351.65729,79250.0%26.1%
53.13%321.95779,43260.0%47.1%
55.17%295.584110,70050.0%60.0%
51.72%291.55968,70362.5%38.5%
34.62%276.078810,82450.0%21.4%
44.44%271.876610,45442.9%45.0%
50.00%261.76948,97641.7%57.1%
45.83%243.866711,35914.3%58.8%
43.48%236.077611,48512.5%60.0%
56.52%235.383511,77254.5%58.3%
40.91%222.864910,08545.5%36.4%
68.18%225.186910,73466.7%70.0%
52.38%225.878111,49162.5%46.1%
50.00%224.573711,14842.9%53.3%
55.00%214.775210,22170.0%40.0%
42.86%212.672510,93950.0%40.0%
38.10%216.480811,87922.2%50.0%
57.89%191.75478,92966.7%50.0%
61.11%184.980312,12887.5%40.0%
56.25%175.279811,73750.0%58.3%
37.50%165.474010,26544.4%28.6%
56.25%163.064210,53233.3%70.0%
50.00%164.368610,23050.0%50.0%
21.43%152.15988,02425.0%16.7%
40.00%155.779411,37344.4%33.3%
50.00%141.86719,86433.3%62.5%
42.86%142.375010,77733.3%50.0%
28.57%146.272910,96728.6%28.6%
92.86%146.41,04512,532100.0%85.7%
71.43%145.099514,50175.0%70.0%
42.86%144.262112,32633.3%45.5%
57.14%145.585212,12785.7%28.6%
35.71%143.769111,15840.0%33.3%
69.23%136.18219,84663.6%100.0%
61.54%133.28349,80050.0%80.0%
69.23%135.674311,54980.0%62.5%
38.46%135.578711,10242.9%33.3%
46.15%131.86329,57737.5%60.0%
53.85%134.16759,63360.0%50.0%
41.67%125.868511,06260.0%28.6%
36.36%116.091911,98125.0%42.9%
55.56%104.45408,49357.1%50.0%
70.00%103.976912,55380.0%60.0%
66.67%96.299012,44560.0%75.0%
33.33%92.87779,88525.0%40.0%
44.44%92.759610,55866.7%33.3%
44.44%96.01,03413,56750.0%42.9%
55.56%95.482513,12875.0%40.0%
33.33%93.874710,66933.3%33.3%
77.78%95.884611,60980.0%75.0%
37.50%82.592313,28966.7%20.0%
62.50%84.591711,25275.0%50.0%
25.00%84.576710,29533.3%20.0%
25.00%82.367310,6160.0%40.0%
28.57%74.785611,9980.0%50.0%
57.14%76.189911,71475.0%33.3%
57.14%75.272111,49666.7%50.0%
42.86%72.05099,244100.0%20.0%
42.86%71.673411,53320.0%100.0%
42.86%74.480011,6100.0%50.0%
71.43%74.867310,92266.7%75.0%
28.57%76.67787,90825.0%33.3%
57.14%72.882511,28466.7%50.0%
42.86%75.380212,23250.0%40.0%
28.57%71.675012,78233.3%25.0%
42.86%76.987111,87075.0%0.0%
57.14%74.070410,60075.0%33.3%
71.43%75.582213,071100.0%66.7%
71.43%71.165711,72475.0%66.7%
57.14%74.81,01512,6750.0%66.7%
42.86%72.681512,24366.7%25.0%
50.00%65.988111,58366.7%33.3%
83.33%61.369110,517100.0%66.7%
50.00%65.36928,88550.0%50.0%
50.00%63.45669,96666.7%33.3%
50.00%63.678611,4390.0%60.0%
33.33%65.271314,1030.0%50.0%
50.00%62.877911,19633.3%66.7%
40.00%53.976414,598100.0%25.0%
60.00%50.95186,98475.0%0.0%
20.00%55.193610,9340.0%50.0%
40.00%52.26759,2040.0%66.7%
80.00%54.889511,67250.0%100.0%
20.00%53.872711,51633.3%0.0%
60.00%51.859810,984100.0%50.0%
40.00%56.792515,5740.0%50.0%
40.00%56.373410,50366.7%0.0%
40.00%54.789211,7070.0%66.7%
60.00%55.884512,78733.3%100.0%
60.00%53.074112,51150.0%66.7%
20.00%56.375311,4970.0%25.0%
60.00%54.677111,174100.0%0.0%
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Neeko vs Vayne - Frequently Asked Questions

How does Neeko do against Vayne in League of Legends?

Vayne wins the Neeko vs Vayne matchup with a 71.4% win rate compared to Neeko's 28.6%, a 42.9 percentage point difference. This data is based on 7 recent ranked games in patch 26.4.

How does Neeko do against Vayne in the early game?

In the early game, Vayne has the advantage against Neeko with a 100.0% win rate versus 0.0%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Neeko do against Vayne in the late game?

In the late game, Neeko takes over the Neeko vs Vayne matchup with a 50.0% win rate compared to 50.0%. Neeko scales better into team fights and objective contests after 25 minutes.

Who wins the Neeko vs Vayne matchup?

Vayne wins the matchup against Neeko with a 71.4% win rate in League of Legends patch 26.4. The 42.9 percentage point advantage means Vayne is significantly favored in this lane matchup based on 7 games analyzed.

What is the best Neeko build against Vayne?

The best Neeko build against Vayne includes Luden's Echo, Stormsurge, Hextech Rocketbelt with Sorcerer's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Neeko runes against Vayne?

The best Neeko runes against Vayne use the Sorcery primary tree with Domination secondary. This rune setup achieves a 100.0% win rate in the Neeko vs Vayne matchup. See the full rune breakdown in the matchup comparison above.

Does Neeko counter Vayne?

No, Neeko struggles against Vayne with only a 28.6% win rate. Vayne has the advantage in this matchup. Neeko players should focus on safe farming and avoiding extended trades to minimize Vayne's lead.

How do I play Neeko against Vayne?

When playing Neeko against Vayne, play cautiously and avoid Vayne's power spikes. Focus on safe farming — you outscale Vayne in the late game. Use the matchup-specific build and runes above to optimize your chances.