
Ryzevs Vayne
Ryze vs Vayne is a decisive matchup in LoL patch 26.3. Vayne wins with a 76.9% win rate (+53.8%) over Ryze based on 13 games. Vayne holds the advantage in both the early and late game. Below you'll find the best Ryze build, runes, laning stats, and strategies for the Ryze vs Vayne matchup.
Ryze Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Ryze performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Ryze vs Vayne Matchup?

Ryze vs Vayne Matchup Summary
The Ryze vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 13 recent matches analyzed, Vayne wins with a 76.9% win rate compared to Ryze's 23.1%, giving Vayne a 53.8 percentage point advantage. Vayne dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Ryze players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Ryze leads by 0.6s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne has a strong advantage in this matchup. Ryze players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Vayne overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Ryze vs Vayne Laning Phase Breakdown
Ryze is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Ryze holds advantages in farming, crowd control and sustain, making them the stronger laner in this matchup.
Best Ryze Build Against Vayne
Ionian Boots of Lucidity is the optimal boots choice against Vayne, providing the mobility and stats Ryze needs most in this matchup. The top-performing core items for Ryze against Vayne are Rod of Ages, Rabadon's Deathcap and Seraph's Embrace. This combination gives Ryze an effective balance of damage, survivability, and utility for the matchup. This build achieves a solid 50.0% win rate across 2 games, proving it to be a reliable item path when facing Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Ryze vs Vayne matchup.
Early Game vs Late Game
Vayne dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Ryze. This lopsided early game means Vayne can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Vayne is far superior in the late game (25+ minutes), boasting a 70.0% win rate — 40.0 points above Ryze. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.
Vayne holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Ryze players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Ryze Runes Against Vayne
The Sorcery and Precision rune setup gives Ryze the best tools to compete against Vayne in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Ryze matchup data for League of Legends patch 26.3. The table below shows Ryze's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Ryze build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 37.19% | 199 | 7.1 | 779 | 11,277 | 35.2% | 39.6% | |
| 43.52% | 193 | 7.1 | 784 | 11,384 | 40.6% | 47.1% | |
| 45.00% | 140 | 7.2 | 924 | 12,139 | 42.0% | 47.9% | |
| 41.67% | 132 | 7.1 | 861 | 12,040 | 36.4% | 45.5% | |
| 44.17% | 120 | 7.4 | 748 | 12,394 | 46.9% | 42.3% | |
| 34.95% | 103 | 7.3 | 770 | 11,675 | 39.2% | 30.8% | |
| 50.98% | 102 | 6.8 | 930 | 11,621 | 54.9% | 47.1% | |
| 39.78% | 93 | 7.1 | 809 | 11,695 | 44.2% | 36.0% | |
| 40.22% | 92 | 7.0 | 744 | 10,946 | 32.6% | 47.8% | |
| 44.44% | 90 | 6.7 | 736 | 11,530 | 45.5% | 43.5% | |
| 49.41% | 85 | 7.2 | 798 | 11,255 | 48.0% | 51.4% | |
| 46.43% | 84 | 7.3 | 813 | 12,175 | 50.0% | 43.8% | |
| 31.58% | 76 | 6.8 | 741 | 11,449 | 31.6% | 31.6% | |
| 47.37% | 76 | 7.3 | 890 | 13,043 | 62.1% | 38.3% | |
| 41.43% | 70 | 6.8 | 929 | 12,534 | 30.0% | 50.0% | |
| 50.75% | 67 | 6.9 | 822 | 12,498 | 38.5% | 58.5% | |
| 43.94% | 66 | 6.9 | 962 | 11,626 | 41.9% | 45.7% | |
| 50.77% | 65 | 7.1 | 933 | 12,442 | 50.0% | 51.7% | |
| 45.76% | 59 | 7.1 | 850 | 11,304 | 35.3% | 60.0% | |
| 42.37% | 59 | 7.3 | 782 | 11,889 | 44.0% | 41.2% | |
| 48.21% | 56 | 7.1 | 897 | 12,290 | 48.1% | 48.3% | |
| 60.00% | 55 | 6.9 | 978 | 12,753 | 50.0% | 67.7% | |
| 49.06% | 53 | 7.2 | 924 | 12,291 | 54.5% | 45.2% | |
| 55.77% | 52 | 7.5 | 749 | 11,717 | 64.5% | 42.9% | |
| 44.23% | 52 | 7.1 | 748 | 11,146 | 27.6% | 65.2% | |
| 44.00% | 50 | 7.5 | 813 | 11,815 | 44.4% | 43.5% | |
| 52.08% | 48 | 6.7 | 874 | 10,951 | 40.7% | 66.7% | |
| 46.81% | 47 | 7.4 | 986 | 12,695 | 52.6% | 42.9% | |
| 32.61% | 46 | 6.9 | 805 | 11,264 | 23.8% | 40.0% | |
| 48.89% | 45 | 6.7 | 782 | 11,893 | 47.4% | 50.0% | |
| 47.62% | 42 | 7.2 | 776 | 12,027 | 38.9% | 54.2% | |
| 48.65% | 37 | 7.7 | 949 | 12,990 | 63.2% | 33.3% | |
| 41.67% | 36 | 7.6 | 1,251 | 13,580 | 46.1% | 39.1% | |
| 65.71% | 35 | 7.8 | 929 | 12,786 | 77.8% | 52.9% | |
| 44.12% | 34 | 6.9 | 859 | 12,322 | 56.3% | 33.3% | |
| 51.52% | 33 | 7.1 | 833 | 13,559 | 69.2% | 40.0% | |
| 42.42% | 33 | 6.9 | 817 | 12,631 | 40.0% | 43.5% | |
| 56.25% | 32 | 7.0 | 851 | 11,411 | 60.0% | 50.0% | |
| 70.97% | 31 | 6.4 | 817 | 12,225 | 86.7% | 56.3% | |
| 62.07% | 29 | 7.0 | 792 | 11,818 | 66.7% | 57.1% | |
| 60.71% | 28 | 7.5 | 976 | 12,025 | 63.6% | 58.8% | |
| 25.93% | 27 | 7.1 | 962 | 9,870 | 27.8% | 22.2% | |
| 46.15% | 26 | 7.5 | 910 | 11,894 | 35.7% | 58.3% | |
| 40.00% | 25 | 7.0 | 788 | 11,330 | 38.5% | 41.7% | |
| 40.00% | 25 | 7.1 | 803 | 12,161 | 50.0% | 35.3% | |
| 41.67% | 24 | 7.8 | 1,022 | 13,561 | 54.5% | 30.8% | |
| 50.00% | 24 | 6.8 | 867 | 12,013 | 36.4% | 61.5% | |
| 54.55% | 22 | 7.1 | 906 | 13,114 | 70.0% | 41.7% | |
| 45.45% | 22 | 6.5 | 1,055 | 11,238 | 41.7% | 50.0% | |
| 27.27% | 22 | 7.2 | 973 | 11,904 | 44.4% | 15.4% | |
| 33.33% | 21 | 7.1 | 855 | 12,263 | 11.1% | 50.0% | |
| 47.62% | 21 | 6.5 | 793 | 11,244 | 27.3% | 70.0% | |
| 66.67% | 21 | 7.9 | 920 | 13,825 | 77.8% | 58.3% | |
| 65.00% | 20 | 7.5 | 845 | 12,005 | 75.0% | 58.3% | |
| 55.00% | 20 | 6.9 | 1,010 | 12,237 | 66.7% | 50.0% | |
| 52.63% | 19 | 7.1 | 824 | 12,188 | 66.7% | 40.0% | |
| 57.89% | 19 | 7.1 | 868 | 12,098 | 60.0% | 55.6% | |
| 50.00% | 18 | 7.1 | 1,084 | 12,273 | 42.9% | 54.5% | |
| 83.33% | 18 | 7.5 | 921 | 11,919 | 100.0% | 72.7% | |
| 58.82% | 17 | 7.2 | 957 | 13,913 | 60.0% | 58.3% | |
| 58.82% | 17 | 7.3 | 1,112 | 13,545 | 16.7% | 81.8% | |
| 25.00% | 16 | 7.6 | 760 | 9,931 | 22.2% | 28.6% | |
| 25.00% | 16 | 7.2 | 1,152 | 11,386 | 12.5% | 37.5% | |
| 40.00% | 15 | 6.5 | 796 | 12,137 | 33.3% | 44.4% | |
| 57.14% | 14 | 6.7 | 799 | 12,080 | 25.0% | 100.0% | |
| 57.14% | 14 | 7.2 | 1,002 | 13,060 | 66.7% | 50.0% | |
| 42.86% | 14 | 6.8 | 924 | 10,359 | 55.6% | 20.0% | |
| 42.86% | 14 | 7.4 | 801 | 11,422 | 28.6% | 57.1% | |
| 78.57% | 14 | 7.5 | 1,004 | 13,126 | 80.0% | 77.8% | |
| 23.08% | 13 | 7.0 | 937 | 13,993 | 0.0% | 30.0% | |
| 53.85% | 13 | 6.8 | 890 | 10,693 | 50.0% | 60.0% | |
| 38.46% | 13 | 7.1 | 788 | 12,554 | 33.3% | 42.9% | |
| 58.33% | 12 | 7.2 | 856 | 14,632 | 66.7% | 55.6% | |
| 66.67% | 12 | 7.7 | 975 | 10,128 | 75.0% | 50.0% | |
| 63.64% | 11 | 6.8 | 796 | 12,821 | 66.7% | 60.0% | |
| 54.55% | 11 | 7.5 | 1,010 | 13,902 | 60.0% | 50.0% | |
| 45.45% | 11 | 7.1 | 825 | 11,255 | 33.3% | 60.0% | |
| 72.73% | 11 | 7.0 | 813 | 12,580 | 75.0% | 71.4% | |
| 40.00% | 10 | 7.3 | 915 | 11,903 | 25.0% | 50.0% | |
| 40.00% | 10 | 7.8 | 864 | 11,073 | 50.0% | 25.0% | |
| 50.00% | 10 | 7.5 | 1,039 | 14,613 | 50.0% | 50.0% | |
| 60.00% | 10 | 7.6 | 829 | 8,452 | 50.0% | 75.0% | |
| 55.56% | 9 | 6.6 | 830 | 11,130 | 60.0% | 50.0% | |
| 33.33% | 9 | 6.9 | 782 | 11,691 | 33.3% | 33.3% | |
| 37.50% | 8 | 5.6 | 994 | 10,090 | 0.0% | 75.0% | |
| 12.50% | 8 | 6.8 | 949 | 9,980 | 0.0% | 25.0% | |
| 57.14% | 7 | 6.8 | 1,126 | 14,920 | 33.3% | 75.0% | |
| 57.14% | 7 | 7.6 | 983 | 12,812 | 50.0% | 60.0% | |
| 42.86% | 7 | 7.6 | 832 | 12,182 | 25.0% | 66.7% | |
| 28.57% | 7 | 6.8 | 916 | 12,123 | 33.3% | 25.0% | |
| 71.43% | 7 | 7.9 | 922 | 10,975 | 100.0% | 50.0% | |
| 57.14% | 7 | 6.7 | 1,224 | 14,504 | 50.0% | 60.0% | |
| 57.14% | 7 | 7.6 | 766 | 7,827 | 66.7% | 0.0% | |
| 71.43% | 7 | 7.4 | 1,242 | 16,367 | 100.0% | 66.7% | |
| 66.67% | 6 | 6.1 | 847 | 11,353 | 100.0% | 50.0% | |
| 50.00% | 6 | 6.6 | 707 | 11,458 | 66.7% | 33.3% | |
| 50.00% | 6 | 7.3 | 667 | 13,252 | 0.0% | 60.0% | |
| 16.67% | 6 | 7.5 | 951 | 12,042 | 33.3% | 0.0% | |
| 66.67% | 6 | 8.2 | 764 | 9,650 | 75.0% | 50.0% | |
| 50.00% | 6 | 6.8 | 1,194 | 16,721 | 50.0% | 50.0% | |
| 0.00% | 5 | 6.1 | 929 | 11,371 | 0.0% | 0.0% | |
| 60.00% | 5 | 5.5 | 918 | 10,972 | 75.0% | 0.0% | |
| 40.00% | 5 | 7.1 | 1,251 | 16,354 | 0.0% | 40.0% | |
| 40.00% | 5 | 7.1 | 1,060 | 13,841 | 100.0% | 25.0% | |
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Ryze vs Vayne - Frequently Asked Questions
How does Ryze do against Vayne in League of Legends?
Vayne wins the Ryze vs Vayne matchup with a 76.9% win rate compared to Ryze's 23.1%, a 53.8 percentage point difference. This data is based on 13 recent ranked games in patch 26.3.
How does Ryze do against Vayne in the early game?
In the early game, Vayne has the advantage against Ryze with a 100.0% win rate versus 0.0%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Ryze do against Vayne in the late game?
In the late game, Vayne takes over the Ryze vs Vayne matchup with a 70.0% win rate compared to 30.0%. Vayne scales better into team fights and objective contests after 25 minutes.
Who wins the Ryze vs Vayne matchup?
Vayne wins the matchup against Ryze with a 76.9% win rate in League of Legends patch 26.3. The 53.8 percentage point advantage means Vayne is significantly favored in this lane matchup based on 13 games analyzed.
What is the best Ryze build against Vayne?
The best Ryze build against Vayne includes Rod of Ages, Rabadon's Deathcap, Seraph's Embrace with Ionian Boots of Lucidity. This build achieves a 50.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Ryze runes against Vayne?
The best Ryze runes against Vayne use the Sorcery primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Ryze vs Vayne matchup. See the full rune breakdown in the matchup comparison above.
Does Ryze counter Vayne?
No, Ryze struggles against Vayne with only a 23.1% win rate. Vayne has the advantage in this matchup. Ryze players should focus on safe farming and avoiding extended trades to minimize Vayne's lead.
How do I play Ryze against Vayne?
When playing Ryze against Vayne, play cautiously and avoid Vayne's power spikes. Look for jungle assistance and team-dependent plays since Vayne has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.