Ryze Runes
Best Ryze runes for LoL Patch 26.1 - Phase Rush from the Sorcery tree with Resolve secondary (72.2% WR, 0.7% pick rate). Ryze's optimal primary runes are Phase Rush, Manaflow Band, Transcendence, Gathering Storm. Secondary tree: Second Wind, Overgrowth.
Arcane Mastery
Ryze's spells deal extra damage based on his Bonus Mana, and he gains a percentage increase to his maximum Mana based on his Ability Power. 
Overload
Passively, Ryze's other basic abilities reset the cooldown of Overload and charge a rune. When Ryze casts Overload with 2 runes charged, he gains a brief burst of Move Speed.
On cast, Ryze throws a charge of pure energy in a line, dealing damage to the first enemy struck. If the target has Flux on it, Overload deals extra damage and bounces to nearby enemies with Flux.Cost:- 40/
- 38/
- 36/
- 34/
- 32
Cooldown:- 5
Range:- 1000
Rune Prison
Ryze traps a target in a cage of runes, damaging them and slowing their movement. If the target has Flux on it, they are instead rooted.
Cost:- 50/
- 60/
- 70/
- 80/
- 90
Cooldown:- 11/
- 11/
- 10/
- 10/
- 9
Range:- 615
Spell Flux
Ryze releases an orb of pure magical power that damages an enemy and debuffs all nearby enemies. Ryze's spells have additional effects against the debuffed enemy.
Cost:- 35/
- 45/
- 55/
- 65/
- 75
Cooldown:- 4/
- 3/
- 3/
- 3/
- 3
Range:- 615
Realm Warp
Passively, Overload deals even more damage against targets with Flux.
On cast, Ryze creates a portal to a nearby location. After a few seconds, allies standing near the portal are teleported to the target location.Cost:- 100
Cooldown:- 180/
- 160/
- 140
Range:- 3000
- Mage
Ryze performs best with Phase Rush as the keystone rune from the Sorcery tree. Ryze's optimal primary runes are Phase Rush, Manaflow Band, Transcendence, Gathering Storm. Ryze's secondary rune tree is Resolve with Second Wind, Overgrowth. This rune setup achieves a 72.22% win rate (+24.2% win rate difference) with a 0.7% pick rate across 18 Ryze games.
Primary Tree
Sorcery
Phase RushHitting an enemy champion with 3 attacks or separate abilities within 4s grants
Cooldown: 30s - 10s
Manaflow BandHitting an enemy champion with an ability permanently increases your maximum mana by 25, up to 250 mana.
After reaching 250 bonus mana, restore 1% of your missing mana every 5 seconds.
Cooldown: 15 seconds
TranscendenceGain bonuses upon reaching the following levels:
Level 5: +5
Level 8: +5
Level 11: On Champion takedown, reduce the remaining cooldown of basic abilities by 20%.
Gathering StormEvery 10 min gain AP or AD,
10 min: + 8 AP or 5 AD
20 min: + 24 AP or 14 AD
30 min: + 48 AP or 29 AD
40 min: + 80 AP or 48 AD
50 min: + 120 AP or 72 AD
60 min: + 168 AP or 101 AD
etc...
Second WindAfter taking damage from an enemy champion, heal for 4% of your missing health over 10s.
OvergrowthAbsorb life essence from monsters or enemy minions that die near you, permanently gaining 3 maximum health for every 8.
When you've absorbed 120 monsters or enemy minions, gain an additional 3.5% maximum health.
This alternative Ryze rune build uses Phase Rush as the keystone from the Sorcery tree. The primary runes are Phase Rush, Manaflow Band, Transcendence, Gathering Storm. Ryze's secondary rune tree is Resolve with Bone Plating, Overgrowth. This setup achieves a 61.54% win rate (+13.5% win rate difference) with a 1.0% pick rate across 26 games.
Primary Tree
SorceryPhase RushHitting an enemy champion with 3 attacks or separate abilities within 4s grants
Cooldown: 30s - 10s
Manaflow BandHitting an enemy champion with an ability permanently increases your maximum mana by 25, up to 250 mana.
After reaching 250 bonus mana, restore 1% of your missing mana every 5 seconds.
Cooldown: 15 seconds
TranscendenceGain bonuses upon reaching the following levels:
Level 5: +5
Level 8: +5
Level 11: On Champion takedown, reduce the remaining cooldown of basic abilities by 20%.
Gathering StormEvery 10 min gain AP or AD,
10 min: + 8 AP or 5 AD
20 min: + 24 AP or 14 AD
30 min: + 48 AP or 29 AD
40 min: + 80 AP or 48 AD
50 min: + 120 AP or 72 AD
60 min: + 168 AP or 101 AD
etc...
Bone PlatingAfter taking damage from an enemy champion, the next 3 spells or attacks you receive from them deal 30-60 (based on level) less damage.
Duration: 1.5s
Cooldown: 55s
OvergrowthAbsorb life essence from monsters or enemy minions that die near you, permanently gaining 3 maximum health for every 8.
When you've absorbed 120 monsters or enemy minions, gain an additional 3.5% maximum health.
Sona
Ornn
Aurelion Sol
NidaleeRyze Runes - Frequently Asked Questions
What are the best Ryze runes in patch 26.1?
The best Ryze runes in patch 26.1 use the Sorcery tree with Phase Rush, Manaflow Band, Transcendence, and Gathering Storm, and the Resolve tree with Second Wind and Overgrowth. This rune setup achieves a 72.2% win rate with a 0.7% pick rate.
What is the win rate for Ryze's best rune page?
Ryze's best rune page has a 72.2% win rate in patch 26.1, which is +24.2% compared to Ryze's average win rate. This rune setup has a 0.7% pick rate among Ryze players.
What keystone should I use on Ryze?
Phase Rush from the Sorcery tree is the best keystone rune for Ryze in patch 26.1. This keystone synergizes well with Ryze's kit and provides a 72.2% win rate.
What is Ryze's primary rune tree?
Ryze's primary rune tree is Sorcery. The optimal Sorcery runes for Ryze are Phase Rush, Manaflow Band, Transcendence, and Gathering Storm, with Phase Rush being the keystone of choice.
What is Ryze's secondary rune tree?
Ryze's best secondary rune tree is Resolve. The recommended Resolve runes are Second Wind and Overgrowth, which complement Ryze's Sorcery primary tree.
What are alternative rune setups for Ryze?
An alternative Ryze rune setup uses Phase Rush from the Sorcery tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.
How popular are Ryze's runes?
Ryze's top rune page has a 0.7% pick rate in patch 26.1. This indicates that 0.7% of Ryze players use the Phase Rush setup with Sorcery and Resolve trees.