Ryze Runes
The top Ryze runes in LoL patch 25.23 are Phase Rush, Manaflow Band, Transcendence, Gathering Storm for Ryze's primary runes. Ryze's runes in his secondary tree best utilizes Presence of Mind and Legend: Haste. These Ryze rune choices provide the best Ryze rune build for ranked.
Arcane Mastery
Ryze's spells deal extra damage based on his Bonus Mana, and he gains a percentage increase to his maximum Mana based on his Ability Power. 
Overload
Passively, Ryze's other basic abilities reset the cooldown of Overload and charge a rune. When Ryze casts Overload with 2 runes charged, he gains a brief burst of Move Speed.
On cast, Ryze throws a charge of pure energy in a line, dealing damage to the first enemy struck. If the target has Flux on it, Overload deals extra damage and bounces to nearby enemies with Flux.Cost:- 40/
- 38/
- 36/
- 34/
- 32
Cooldown:- 5
Range:- 1000
Rune Prison
Ryze traps a target in a cage of runes, damaging them and slowing their movement. If the target has Flux on it, they are instead rooted.
Cost:- 50/
- 60/
- 70/
- 80/
- 90
Cooldown:- 11/
- 11/
- 10/
- 10/
- 9
Range:- 615
Spell Flux
Ryze releases an orb of pure magical power that damages an enemy and debuffs all nearby enemies. Ryze's spells have additional effects against the debuffed enemy.
Cost:- 35/
- 45/
- 55/
- 65/
- 75
Cooldown:- 4/
- 3/
- 3/
- 3/
- 3
Range:- 615
Realm Warp
Passively, Overload deals even more damage against targets with Flux.
On cast, Ryze creates a portal to a nearby location. After a few seconds, allies standing near the portal are teleported to the target location.Cost:- 100
Cooldown:- 180/
- 160/
- 140
Range:- 3000
- Mage
Ryze performs best with Phase Rush as the keystone rune. The optimal primary runes for Ryze include Phase Rush, Manaflow Band, Transcendence. This rune setup achieves a 1.00% win rate across 2 Ryze games.
Primary Tree
Sorcery
This alternative Ryze rune build uses Phase Rush as the keystone. This setup provides a different playstyle for Ryze and achieves a 1.00% win rate. Consider this rune page when facing specific matchups or team compositions.
Primary Tree
Sorcery
Ryze Runes - Frequently Asked Questions
What are the best Ryze runes?
The best Ryze runes in patch 25.23 are Phase Rush, Manaflow Band, Transcendence, and Gathering Storm for the primary tree, and Presence of Mind and Legend: Haste for the secondary tree. These runes provide optimal performance for Ryze.
What keystone should I use on Ryze?
Phase Rush is the best keystone rune for Ryze. This keystone synergizes well with Ryze's abilities and provides maximum value in most matchups.
What are Ryze's secondary runes?
Ryze's best secondary runes are Presence of Mind and Legend: Haste. These secondary runes complement Ryze's primary rune choices and enhance overall effectiveness.
Can I use different rune setups on Ryze?
Yes, Ryze can utilize different rune setups depending on matchup and playstyle. While Phase Rush is most popular, alternative keystones may work better in specific situations.
