Lee Sin - League of Legends Champion
Win Rate
46.8%
Pick Rate
2.9%

Lee Sinvs Vayne

FFighterAssassin
Patch26.9
Matches514,344
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 10, 2026
MethodologyData Methodology

Lee Sin vs Vayne is a decisive matchup in LoL patch 26.9. Vayne wins with a 66.7% win rate (+33.3%) over Lee Sin based on 6 games. Lee Sin wins the early laning phase while Vayne scales better into the late game. Below you'll find the best Lee Sin build, runes, laning stats, and strategies for the Lee Sin vs Vayne matchup.

Lee Sin Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Lee Sin performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vayne - 33.3% win rateVayne(33.3%)
Lee Sin - 33.3% win rate in this matchup
Lee Sin
33.3% WR
VS
Vayne vs Lee Sin matchup - 66.7% win rate
Vayne
66.7% WR

Who Wins the Lee Sin vs Vayne Matchup?

Vayne wins the Lee Sin vs Vayne matchup
Winner
Vayne
Matches: 6
33.3%
Win Rate
66.7%
2.7
CS / min
3.0
923
DMG / min
644
14,686
Gold / game
11,653
547
Heal / min
228
1,358
DMG Mitigated / min
469
0.8
CC / min
0.4
100.0%
Early Game WR
0.0%
20.0%
Late Game WR
80.0%

Lee Sin vs Vayne Matchup Summary

The Lee Sin vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 6 recent matches analyzed, Vayne wins with a 66.7% win rate compared to Lee Sin's 33.3%, giving Vayne a 33.3 percentage point advantage. Game phase dynamics play a critical role here: Lee Sin controls the early laning stage, but Vayne outscales as the game goes longer. The matchup shifts dramatically depending on game length — Lee Sin needs to press advantages before Vayne reaches their power spikes, while Vayne should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Lee Sin leads by 1,208 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne has a strong advantage in this matchup. Lee Sin players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Vayne overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Lee Sin vs Vayne Laning Phase Breakdown

Lee Sin wins the laning phase against Vayne in League of Legends

Lee Sin is favored during the laning phase against Vayne, winning 4 out of 5 key stat categories. Lee Sin holds advantages in damage, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
2.7Lee Sin
3.0Vayne
Lee Sin and Vayne farm at nearly identical rates in this matchup, with only a 0.3 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
923Lee Sin
644Vayne
Lee Sin heavily out-damages Vayne by 279 DMG/min, dominating both short trades and all-in fights. Vayne should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Lee Sin's sustained damage advantage take over.
Economy
14,686Lee Sin
11,653Vayne
Lee Sin generates a commanding 3,034 more gold per game than Vayne. This substantial economic advantage means Lee Sin consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Vayne should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.8Lee Sin
0.4Vayne
Lee Sin provides 0.3 seconds more crowd control per minute than Vayne, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Lee Sin coordinate with their jungler and control the pace of skirmishes.
Sustain
1,905Lee Sin
696Vayne
Lee Sin vastly out-sustains Vayne, healing and mitigating 1,208 more damage per minute. This massive durability gap means Lee Sin can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Best Lee Sin Build Against Vayne

Mercury's Treads is the optimal boots choice against Vayne, providing the mobility and stats Lee Sin needs most in this matchup. The top-performing core items for Lee Sin against Vayne are Eclipse, Sundered Sky and Spirit Visage. This combination gives Lee Sin an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Lee Sin vs Vayne matchup.

Early Game vs Late Game

Early Game
Lee Sin
100.0%
+100.0% advantage
Lee Sin early game win rateLee Sin100.0%
Vayne early game win rateVayne0.0%
Late Game
Vayne
80.0%
+60.0% advantage
Lee Sin late game win rateLee Sin20.0%
Vayne late game win rateVayne80.0%

Lee Sin dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Vayne. This lopsided early game means Lee Sin can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Vayne is far superior in the late game (25+ minutes), boasting a 80.0% win rate — 60.0 points above Lee Sin. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Lee Sin must aggressively press their early advantage and close out the game before Vayne reaches their scaling breakpoints. If Vayne survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Lee Sin Runes Against Vayne

Precision rune tree - Lee Sin primary runes vs VaynePrecision
Conqueror - best Lee Sin rune vs VayneTriumph - best Lee Sin rune vs VayneLegend: Alacrity - best Lee Sin rune vs VayneCoup de Grace - best Lee Sin rune vs Vayne
Inspiration rune tree - Lee Sin secondary runes vs VayneInspiration
Magical Footwear - best Lee Sin rune vs VayneCosmic Insight - best Lee Sin rune vs Vayne
100.0% WR

The Precision and Inspiration rune setup gives Lee Sin the best tools to compete against Vayne in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Lee Sin matchup data for League of Legends patch 26.9. The table below shows Lee Sin's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Lee Sin build, runes, laning stats, and early vs late game analysis for that specific matchup.

Lee Sin matchup win rates and stats in League of Legends patch 26.9
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
51.39%1440.861712,25253.4%49.3%
57.78%1350.967112,89966.7%51.3%
52.25%1110.863512,47857.1%48.4%
38.18%1100.867112,54544.7%33.3%
44.34%1060.970813,49948.6%42.3%
42.00%1000.867612,51346.3%37.0%
37.11%970.863512,31737.2%37.0%
47.87%940.871612,11145.0%50.0%
44.32%880.968413,12441.7%46.1%
45.88%850.971612,71260.0%33.3%
47.06%850.868812,41355.6%40.8%
46.15%651.065313,10339.1%50.0%
45.31%640.970213,27226.1%56.1%
49.18%610.866712,81246.7%51.6%
52.54%590.972812,70161.5%45.5%
48.28%580.766712,32553.3%42.9%
50.00%581.066012,12748.0%51.5%
38.18%550.960111,36340.7%35.7%
40.74%541.172913,04331.6%45.7%
44.44%540.965312,67444.4%44.4%
53.85%530.861012,37965.0%46.9%
50.00%521.271612,31164.0%37.0%
52.08%480.770212,18764.0%39.1%
62.22%451.173312,71063.6%60.9%
31.82%441.269712,78031.6%32.0%
46.34%410.960812,13262.5%36.0%
47.50%400.873912,29852.9%43.5%
37.50%400.866212,13033.3%40.9%
57.50%401.070013,17565.0%50.0%
41.03%390.966912,23935.3%45.5%
40.54%370.874512,92738.5%41.7%
48.48%330.857811,61256.3%41.2%
58.06%311.074012,90341.7%68.4%
37.93%290.765312,06650.0%26.7%
41.38%290.863612,29254.5%33.3%
42.86%281.282412,58050.0%35.7%
64.00%261.280013,00091.7%38.5%
70.83%241.169011,66578.6%60.0%
26.09%231.868212,81435.7%11.1%
39.13%230.861212,77837.5%40.0%
40.91%221.962811,80860.0%25.0%
50.00%220.862112,50054.5%45.5%
57.14%211.065412,60860.0%54.5%
45.00%200.770712,33725.0%58.3%
35.00%200.959611,92314.3%46.1%
60.00%200.960611,92476.9%28.6%
31.58%191.473011,51337.5%27.3%
44.44%181.363612,05350.0%33.3%
37.50%161.967311,48144.4%28.6%
20.00%150.662612,8550.0%30.0%
46.67%150.770411,70140.0%60.0%
33.33%151.675813,48528.6%37.5%
33.33%151.681913,26550.0%22.2%
33.33%150.971613,33050.0%27.3%
40.00%151.482116,25150.0%36.4%
21.43%142.471011,03125.0%16.7%
64.29%141.064413,48375.0%60.0%
64.29%140.757612,95683.3%50.0%
41.67%121.46269,89542.9%40.0%
33.33%121.069111,93033.3%33.3%
81.82%113.080214,34375.0%85.7%
63.64%111.276012,69160.0%66.7%
30.00%101.966210,69050.0%16.7%
40.00%102.559710,62742.9%33.3%
30.00%102.274412,3660.0%42.9%
66.67%91.161512,44660.0%75.0%
71.43%71.966711,087100.0%50.0%
71.43%71.084415,449100.0%66.7%
28.57%72.26549,48725.0%33.3%
33.33%65.85877,97940.0%0.0%
50.00%65.86979,48766.7%33.3%
33.33%62.792314,686100.0%20.0%
50.00%64.47309,97650.0%50.0%
60.00%51.398313,1710.0%100.0%
60.00%53.26539,15450.0%100.0%
20.00%51.75678,62425.0%0.0%
20.00%55.479711,7570.0%33.3%
0.00%52.158813,2350.0%0.0%
0.00%54.663112,3200.0%0.0%
40.00%55.179611,58250.0%0.0%
80.00%56.796212,384100.0%50.0%

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Lee Sin vs Vayne - Frequently Asked Questions

How does Lee Sin do against Vayne in League of Legends?

Vayne wins the Lee Sin vs Vayne matchup with a 66.7% win rate compared to Lee Sin's 33.3%, a 33.3 percentage point difference. This data is based on 6 recent ranked games in patch 26.9.

How does Lee Sin do against Vayne in the early game?

In the early game, Lee Sin has the advantage against Vayne with a 100.0% win rate versus 0.0%. Lee Sin players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Lee Sin do against Vayne in the late game?

In the late game, Vayne takes over the Lee Sin vs Vayne matchup with a 80.0% win rate compared to 20.0%. Vayne scales better into team fights and objective contests after 25 minutes.

Who wins the Lee Sin vs Vayne matchup?

Vayne wins the matchup against Lee Sin with a 66.7% win rate in League of Legends patch 26.9. The 33.3 percentage point advantage means Vayne is significantly favored in this lane matchup based on 6 games analyzed.

What is the best Lee Sin build against Vayne?

The best Lee Sin build against Vayne includes Eclipse, Sundered Sky, Spirit Visage with Mercury's Treads. Check the matchup breakdown above for the full item path and build order.

What are the best Lee Sin runes against Vayne?

The best Lee Sin runes against Vayne use the Precision primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Lee Sin vs Vayne matchup. See the full rune breakdown in the matchup comparison above.

Does Lee Sin counter Vayne?

No, Lee Sin struggles against Vayne with only a 33.3% win rate. Vayne has the advantage in this matchup. Lee Sin players should focus on safe farming and avoiding extended trades to minimize Vayne's lead.

How do I play Lee Sin against Vayne?

When playing Lee Sin against Vayne, play cautiously and avoid Vayne's power spikes. Look for jungle assistance and team-dependent plays since Vayne has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.