
Lee Sinvs Vayne
Lee Sin vs Vayne is a decisive matchup in LoL patch 26.9. Vayne wins with a 66.7% win rate (+33.3%) over Lee Sin based on 6 games. Lee Sin wins the early laning phase while Vayne scales better into the late game. Below you'll find the best Lee Sin build, runes, laning stats, and strategies for the Lee Sin vs Vayne matchup.
Lee Sin Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Lee Sin performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Lee Sin vs Vayne Matchup?

Lee Sin vs Vayne Matchup Summary
The Lee Sin vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 6 recent matches analyzed, Vayne wins with a 66.7% win rate compared to Lee Sin's 33.3%, giving Vayne a 33.3 percentage point advantage. Game phase dynamics play a critical role here: Lee Sin controls the early laning stage, but Vayne outscales as the game goes longer. The matchup shifts dramatically depending on game length — Lee Sin needs to press advantages before Vayne reaches their power spikes, while Vayne should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Lee Sin leads by 1,208 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne has a strong advantage in this matchup. Lee Sin players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Vayne overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Lee Sin vs Vayne Laning Phase Breakdown
Lee Sin is favored during the laning phase against Vayne, winning 4 out of 5 key stat categories. Lee Sin holds advantages in damage, gold income, crowd control and sustain, making them the stronger laner in this matchup.
Best Lee Sin Build Against Vayne
Mercury's Treads is the optimal boots choice against Vayne, providing the mobility and stats Lee Sin needs most in this matchup. The top-performing core items for Lee Sin against Vayne are Eclipse, Sundered Sky and Spirit Visage. This combination gives Lee Sin an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Lee Sin vs Vayne matchup.
Early Game vs Late Game
Lee Sin dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Vayne. This lopsided early game means Lee Sin can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Vayne is far superior in the late game (25+ minutes), boasting a 80.0% win rate — 60.0 points above Lee Sin. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.
This matchup features a dramatic power shift: Lee Sin must aggressively press their early advantage and close out the game before Vayne reaches their scaling breakpoints. If Vayne survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.
Best Lee Sin Runes Against Vayne
The Precision and Inspiration rune setup gives Lee Sin the best tools to compete against Vayne in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Lee Sin matchup data for League of Legends patch 26.9. The table below shows Lee Sin's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Lee Sin build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 51.39% | 144 | 0.8 | 617 | 12,252 | 53.4% | 49.3% | |
| 57.78% | 135 | 0.9 | 671 | 12,899 | 66.7% | 51.3% | |
| 52.25% | 111 | 0.8 | 635 | 12,478 | 57.1% | 48.4% | |
| 38.18% | 110 | 0.8 | 671 | 12,545 | 44.7% | 33.3% | |
| 44.34% | 106 | 0.9 | 708 | 13,499 | 48.6% | 42.3% | |
| 42.00% | 100 | 0.8 | 676 | 12,513 | 46.3% | 37.0% | |
| 37.11% | 97 | 0.8 | 635 | 12,317 | 37.2% | 37.0% | |
| 47.87% | 94 | 0.8 | 716 | 12,111 | 45.0% | 50.0% | |
| 44.32% | 88 | 0.9 | 684 | 13,124 | 41.7% | 46.1% | |
| 45.88% | 85 | 0.9 | 716 | 12,712 | 60.0% | 33.3% | |
| 47.06% | 85 | 0.8 | 688 | 12,413 | 55.6% | 40.8% | |
| 46.15% | 65 | 1.0 | 653 | 13,103 | 39.1% | 50.0% | |
| 45.31% | 64 | 0.9 | 702 | 13,272 | 26.1% | 56.1% | |
| 49.18% | 61 | 0.8 | 667 | 12,812 | 46.7% | 51.6% | |
| 52.54% | 59 | 0.9 | 728 | 12,701 | 61.5% | 45.5% | |
| 48.28% | 58 | 0.7 | 667 | 12,325 | 53.3% | 42.9% | |
| 50.00% | 58 | 1.0 | 660 | 12,127 | 48.0% | 51.5% | |
| 38.18% | 55 | 0.9 | 601 | 11,363 | 40.7% | 35.7% | |
| 40.74% | 54 | 1.1 | 729 | 13,043 | 31.6% | 45.7% | |
| 44.44% | 54 | 0.9 | 653 | 12,674 | 44.4% | 44.4% | |
| 53.85% | 53 | 0.8 | 610 | 12,379 | 65.0% | 46.9% | |
| 50.00% | 52 | 1.2 | 716 | 12,311 | 64.0% | 37.0% | |
| 52.08% | 48 | 0.7 | 702 | 12,187 | 64.0% | 39.1% | |
| 62.22% | 45 | 1.1 | 733 | 12,710 | 63.6% | 60.9% | |
| 31.82% | 44 | 1.2 | 697 | 12,780 | 31.6% | 32.0% | |
| 46.34% | 41 | 0.9 | 608 | 12,132 | 62.5% | 36.0% | |
| 47.50% | 40 | 0.8 | 739 | 12,298 | 52.9% | 43.5% | |
| 37.50% | 40 | 0.8 | 662 | 12,130 | 33.3% | 40.9% | |
| 57.50% | 40 | 1.0 | 700 | 13,175 | 65.0% | 50.0% | |
| 41.03% | 39 | 0.9 | 669 | 12,239 | 35.3% | 45.5% | |
| 40.54% | 37 | 0.8 | 745 | 12,927 | 38.5% | 41.7% | |
| 48.48% | 33 | 0.8 | 578 | 11,612 | 56.3% | 41.2% | |
| 58.06% | 31 | 1.0 | 740 | 12,903 | 41.7% | 68.4% | |
| 37.93% | 29 | 0.7 | 653 | 12,066 | 50.0% | 26.7% | |
| 41.38% | 29 | 0.8 | 636 | 12,292 | 54.5% | 33.3% | |
| 42.86% | 28 | 1.2 | 824 | 12,580 | 50.0% | 35.7% | |
| 64.00% | 26 | 1.2 | 800 | 13,000 | 91.7% | 38.5% | |
| 70.83% | 24 | 1.1 | 690 | 11,665 | 78.6% | 60.0% | |
| 26.09% | 23 | 1.8 | 682 | 12,814 | 35.7% | 11.1% | |
| 39.13% | 23 | 0.8 | 612 | 12,778 | 37.5% | 40.0% | |
| 40.91% | 22 | 1.9 | 628 | 11,808 | 60.0% | 25.0% | |
| 50.00% | 22 | 0.8 | 621 | 12,500 | 54.5% | 45.5% | |
| 57.14% | 21 | 1.0 | 654 | 12,608 | 60.0% | 54.5% | |
| 45.00% | 20 | 0.7 | 707 | 12,337 | 25.0% | 58.3% | |
| 35.00% | 20 | 0.9 | 596 | 11,923 | 14.3% | 46.1% | |
| 60.00% | 20 | 0.9 | 606 | 11,924 | 76.9% | 28.6% | |
| 31.58% | 19 | 1.4 | 730 | 11,513 | 37.5% | 27.3% | |
| 44.44% | 18 | 1.3 | 636 | 12,053 | 50.0% | 33.3% | |
| 37.50% | 16 | 1.9 | 673 | 11,481 | 44.4% | 28.6% | |
| 20.00% | 15 | 0.6 | 626 | 12,855 | 0.0% | 30.0% | |
| 46.67% | 15 | 0.7 | 704 | 11,701 | 40.0% | 60.0% | |
| 33.33% | 15 | 1.6 | 758 | 13,485 | 28.6% | 37.5% | |
| 33.33% | 15 | 1.6 | 819 | 13,265 | 50.0% | 22.2% | |
| 33.33% | 15 | 0.9 | 716 | 13,330 | 50.0% | 27.3% | |
| 40.00% | 15 | 1.4 | 821 | 16,251 | 50.0% | 36.4% | |
| 21.43% | 14 | 2.4 | 710 | 11,031 | 25.0% | 16.7% | |
| 64.29% | 14 | 1.0 | 644 | 13,483 | 75.0% | 60.0% | |
| 64.29% | 14 | 0.7 | 576 | 12,956 | 83.3% | 50.0% | |
| 41.67% | 12 | 1.4 | 626 | 9,895 | 42.9% | 40.0% | |
| 33.33% | 12 | 1.0 | 691 | 11,930 | 33.3% | 33.3% | |
| 81.82% | 11 | 3.0 | 802 | 14,343 | 75.0% | 85.7% | |
| 63.64% | 11 | 1.2 | 760 | 12,691 | 60.0% | 66.7% | |
| 30.00% | 10 | 1.9 | 662 | 10,690 | 50.0% | 16.7% | |
| 40.00% | 10 | 2.5 | 597 | 10,627 | 42.9% | 33.3% | |
| 30.00% | 10 | 2.2 | 744 | 12,366 | 0.0% | 42.9% | |
| 66.67% | 9 | 1.1 | 615 | 12,446 | 60.0% | 75.0% | |
| 71.43% | 7 | 1.9 | 667 | 11,087 | 100.0% | 50.0% | |
| 71.43% | 7 | 1.0 | 844 | 15,449 | 100.0% | 66.7% | |
| 28.57% | 7 | 2.2 | 654 | 9,487 | 25.0% | 33.3% | |
| 33.33% | 6 | 5.8 | 587 | 7,979 | 40.0% | 0.0% | |
| 50.00% | 6 | 5.8 | 697 | 9,487 | 66.7% | 33.3% | |
| 33.33% | 6 | 2.7 | 923 | 14,686 | 100.0% | 20.0% | |
| 50.00% | 6 | 4.4 | 730 | 9,976 | 50.0% | 50.0% | |
| 60.00% | 5 | 1.3 | 983 | 13,171 | 0.0% | 100.0% | |
| 60.00% | 5 | 3.2 | 653 | 9,154 | 50.0% | 100.0% | |
| 20.00% | 5 | 1.7 | 567 | 8,624 | 25.0% | 0.0% | |
| 20.00% | 5 | 5.4 | 797 | 11,757 | 0.0% | 33.3% | |
| 0.00% | 5 | 2.1 | 588 | 13,235 | 0.0% | 0.0% | |
| 0.00% | 5 | 4.6 | 631 | 12,320 | 0.0% | 0.0% | |
| 40.00% | 5 | 5.1 | 796 | 11,582 | 50.0% | 0.0% | |
| 80.00% | 5 | 6.7 | 962 | 12,384 | 100.0% | 50.0% | |
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Lee Sin vs Vayne - Frequently Asked Questions
How does Lee Sin do against Vayne in League of Legends?
Vayne wins the Lee Sin vs Vayne matchup with a 66.7% win rate compared to Lee Sin's 33.3%, a 33.3 percentage point difference. This data is based on 6 recent ranked games in patch 26.9.
How does Lee Sin do against Vayne in the early game?
In the early game, Lee Sin has the advantage against Vayne with a 100.0% win rate versus 0.0%. Lee Sin players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Lee Sin do against Vayne in the late game?
In the late game, Vayne takes over the Lee Sin vs Vayne matchup with a 80.0% win rate compared to 20.0%. Vayne scales better into team fights and objective contests after 25 minutes.
Who wins the Lee Sin vs Vayne matchup?
Vayne wins the matchup against Lee Sin with a 66.7% win rate in League of Legends patch 26.9. The 33.3 percentage point advantage means Vayne is significantly favored in this lane matchup based on 6 games analyzed.
What is the best Lee Sin build against Vayne?
The best Lee Sin build against Vayne includes Eclipse, Sundered Sky, Spirit Visage with Mercury's Treads. Check the matchup breakdown above for the full item path and build order.
What are the best Lee Sin runes against Vayne?
The best Lee Sin runes against Vayne use the Precision primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Lee Sin vs Vayne matchup. See the full rune breakdown in the matchup comparison above.
Does Lee Sin counter Vayne?
No, Lee Sin struggles against Vayne with only a 33.3% win rate. Vayne has the advantage in this matchup. Lee Sin players should focus on safe farming and avoiding extended trades to minimize Vayne's lead.
How do I play Lee Sin against Vayne?
When playing Lee Sin against Vayne, play cautiously and avoid Vayne's power spikes. Look for jungle assistance and team-dependent plays since Vayne has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.