Neeko - League of Legends Champion
Win Rate
47.6%
Pick Rate
1.4%

Neekovs Cassiopeia

FMageSupport
Patch26.10
Matches1,778,277
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 20, 2026
MethodologyData Methodology

Neeko vs Cassiopeia is a decisive matchup in LoL patch 26.10. Neeko wins with a 80.0% win rate (+60.0%) over Cassiopeia based on 5 games. Neeko holds the advantage in both the early and late game. Below you'll find the best Neeko build, runes, laning stats, and strategies for the Neeko vs Cassiopeia matchup.

Neeko Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Neeko performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Cassiopeia - 80.0% win rateCassiopeia(80.0%)
Neeko - 80.0% win rate in this matchup
Neeko
80.0% WR
VS
Cassiopeia vs Neeko matchup - 20.0% win rate
Cassiopeia
20.0% WR

Who Wins the Neeko vs Cassiopeia Matchup?

Neeko wins the Neeko vs Cassiopeia matchup
Winner
Neeko
Matches: 5
80.0%
Win Rate
20.0%
4.4
CS / min
3.4
919
DMG / min
570
8,399
Gold / game
6,625
73
Heal / min
262
332
DMG Mitigated / min
503
1.5
CC / min
1.0
75.0%
Early Game WR
25.0%
100.0%
Late Game WR
0.0%

Neeko vs Cassiopeia Matchup Summary

The Neeko vs Cassiopeia matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Neeko wins with a 80.0% win rate compared to Cassiopeia's 20.0%, giving Neeko a 60.0 percentage point advantage. Neeko dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Cassiopeia players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Cassiopeia leads by 360 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Neeko players can confidently pick into Cassiopeia and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Cassiopeia away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Neeko vs Cassiopeia Laning Phase Breakdown

Neeko wins the laning phase against Cassiopeia in League of Legends

Neeko is favored during the laning phase against Cassiopeia, winning 4 out of 5 key stat categories. Neeko holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
4.4Neeko
3.4Cassiopeia
Neeko significantly out-farms Cassiopeia by 1.1 CS per minute, accumulating an estimated 16 CS lead by mid game. This substantial farming gap gives Neeko a major gold advantage and earlier item completions. Cassiopeia players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
919Neeko
570Cassiopeia
Neeko heavily out-damages Cassiopeia by 349 DMG/min, dominating both short trades and all-in fights. Cassiopeia should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Neeko's sustained damage advantage take over.
Economy
8,399Neeko
6,625Cassiopeia
Neeko generates a commanding 1,774 more gold per game than Cassiopeia. This substantial economic advantage means Neeko consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Cassiopeia should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.5Neeko
1.0Cassiopeia
Neeko provides 0.5 seconds more crowd control per minute than Cassiopeia, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Neeko coordinate with their jungler and control the pace of skirmishes.
Sustain
405Neeko
765Cassiopeia
Cassiopeia vastly out-sustains Neeko, healing and mitigating 360 more damage per minute. This massive durability gap means Cassiopeia can absorb significant punishment and remain in lane while Neeko is forced to recall. Building grievous wounds early is essential for Neeko, and focusing on burst trade patterns rather than sustained fights is critical.

Best Neeko Build Against Cassiopeia

Sorcerer's Shoes is the optimal boots choice against Cassiopeia, providing the mobility and stats Neeko needs most in this matchup. The top-performing core items for Neeko against Cassiopeia are Luden's Echo, Shadowflame and Zhonya's Hourglass. This combination gives Neeko an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Cassiopeia. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Neeko vs Cassiopeia matchup.

Early Game vs Late Game

Early Game
Neeko
75.0%
+50.0% advantage
Neeko early game win rateNeeko75.0%
Cassiopeia early game win rateCassiopeia25.0%
Late Game
Neeko
100.0%
+100.0% advantage
Neeko late game win rateNeeko100.0%
Cassiopeia late game win rateCassiopeia0.0%

Neeko dominates the early game (first 15 minutes) with a commanding 75.0% win rate — a 50.0 percentage point lead over Cassiopeia. This lopsided early game means Neeko can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Neeko is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Cassiopeia. Extended games heavily favor Neeko, whose kit and scaling make them a dominant force in team fights and objective control.

Neeko holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Cassiopeia players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Neeko Runes Against Cassiopeia

Domination rune tree - Neeko primary runes vs CassiopeiaDomination
Electrocute - best Neeko rune vs CassiopeiaCheap Shot - best Neeko rune vs CassiopeiaGrisly Mementos - best Neeko rune vs CassiopeiaRelentless Hunter - best Neeko rune vs Cassiopeia
Sorcery rune tree - Neeko secondary runes vs CassiopeiaSorcery
Nimbus Cloak - best Neeko rune vs CassiopeiaCelerity - best Neeko rune vs Cassiopeia
100.0% WR

Running Domination primary with Sorcery secondary allows Neeko to press their advantage against Cassiopeia, amplifying the strengths that make this a favorable matchup.


Neeko matchup data for League of Legends patch 26.10. The table below shows Neeko's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Neeko build, runes, laning stats, and early vs late game analysis for that specific matchup.

Neeko matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
40.57%1751.75858,90037.5%43.2%
40.94%1272.36089,18236.2%44.9%
43.36%1131.96179,22457.1%32.8%
56.84%951.86659,39860.0%54.5%
50.54%931.86379,63054.3%48.3%
49.41%851.86249,36659.5%41.7%
45.78%831.866910,27648.1%44.6%
44.74%762.06389,75146.9%43.2%
56.34%712.264310,71158.3%55.3%
41.79%671.869710,49840.9%42.2%
46.03%631.66639,18946.1%46.0%
46.77%621.64858,32054.8%38.7%
45.90%612.86039,76450.0%43.2%
37.74%531.86038,80229.6%46.1%
50.98%511.76359,39456.5%46.4%
56.00%501.76929,67755.0%56.7%
30.61%491.76549,30640.0%24.1%
54.17%481.66309,67664.7%48.4%
46.67%462.170010,64747.1%46.4%
48.84%431.75718,78858.3%36.8%
48.78%411.966210,12028.6%59.3%
47.50%401.76498,77057.1%36.8%
44.74%386.181311,59550.0%40.9%
51.35%375.880911,55946.7%54.5%
58.33%363.069610,39650.0%65.0%
66.67%331.96859,52180.0%55.6%
66.67%331.75949,00553.9%75.0%
46.88%321.877210,83155.6%43.5%
46.67%305.780010,06435.7%56.3%
48.28%291.95799,74027.3%61.1%
50.00%245.083012,14533.3%60.0%
68.18%221.56099,02454.5%81.8%
45.45%223.777610,90350.0%42.9%
52.38%211.55909,79962.5%46.1%
38.10%215.283811,46544.4%33.3%
45.00%205.771110,69655.6%36.4%
42.11%191.76078,66342.9%41.7%
47.37%194.37038,28146.1%50.0%
47.37%192.36279,18230.0%66.7%
61.11%185.486412,63550.0%70.0%
47.06%171.96868,81042.9%50.0%
41.18%173.56629,40657.1%30.0%
62.50%165.783411,05670.0%50.0%
43.75%162.07009,58654.5%20.0%
12.50%163.371110,82811.1%14.3%
68.75%166.087212,98875.0%66.7%
53.33%152.16249,22533.3%66.7%
46.67%153.96948,49442.9%50.0%
21.43%141.859210,96433.3%18.2%
42.86%141.877210,29140.0%44.4%
76.92%134.572112,753100.0%72.7%
41.67%126.290013,08240.0%42.9%
50.00%123.767010,36340.0%57.1%
54.55%113.46687,31942.9%75.0%
72.73%116.477310,97185.7%50.0%
45.45%115.071510,69940.0%50.0%
80.00%106.683912,30466.7%85.7%
50.00%106.289911,34275.0%33.3%
30.00%105.871910,73925.0%33.3%
60.00%105.081611,41371.4%33.3%
50.00%103.35408,73240.0%60.0%
77.78%94.368212,391100.0%66.7%
44.44%95.979112,36150.0%40.0%
77.78%94.575810,67380.0%75.0%
33.33%93.37397,69716.7%66.7%
62.50%84.376212,41150.0%66.7%
75.00%83.086412,99475.0%75.0%
62.50%83.175911,35150.0%75.0%
75.00%81.86829,08875.0%75.0%
62.50%84.978212,51066.7%60.0%
37.50%84.078410,52333.3%40.0%
50.00%85.390813,8700.0%66.7%
37.50%85.18469,78050.0%25.0%
37.50%82.85959,03040.0%33.3%
50.00%81.566610,93150.0%50.0%
42.86%73.61,03111,24133.3%50.0%
28.57%74.989813,1280.0%40.0%
85.71%75.177512,091100.0%66.7%
100.00%71.866311,333100.0%100.0%
42.86%75.967910,65066.7%25.0%
42.86%71.45619,12366.7%25.0%
42.86%75.98039,40460.0%0.0%
33.33%64.084212,1970.0%50.0%
16.67%63.159611,0480.0%25.0%
33.33%61.945211,23350.0%0.0%
50.00%66.11,04712,82650.0%50.0%
50.00%62.585310,5910.0%100.0%
50.00%65.781810,7530.0%60.0%
33.33%64.483212,6550.0%40.0%
66.67%65.088012,12966.7%66.7%
50.00%65.989614,49450.0%50.0%
50.00%61.15149,70333.3%66.7%
66.67%65.91,0819,94566.7%66.7%
80.00%51.877312,871100.0%75.0%
60.00%55.695512,356100.0%33.3%
40.00%53.281812,68066.7%0.0%
60.00%55.087514,429100.0%50.0%
60.00%55.71,07313,48850.0%66.7%
40.00%51.461910,7020.0%66.7%
80.00%54.49198,39975.0%100.0%
60.00%56.91,02414,816100.0%50.0%

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Neeko vs Cassiopeia - Frequently Asked Questions

How does Neeko do against Cassiopeia in League of Legends?

Neeko wins the Neeko vs Cassiopeia matchup with a 80.0% win rate compared to Cassiopeia's 20.0%, a 60.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.10.

How does Neeko do against Cassiopeia in the early game?

In the early game, Neeko has the advantage against Cassiopeia with a 75.0% win rate versus 25.0%. Neeko players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Neeko do against Cassiopeia in the late game?

In the late game, Neeko takes over the Neeko vs Cassiopeia matchup with a 100.0% win rate compared to 0.0%. Neeko scales better into team fights and objective contests after 25 minutes.

Who wins the Neeko vs Cassiopeia matchup?

Neeko wins the matchup against Cassiopeia with a 80.0% win rate in League of Legends patch 26.10. The 60.0 percentage point advantage means Neeko is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Neeko build against Cassiopeia?

The best Neeko build against Cassiopeia includes Luden's Echo, Shadowflame, Zhonya's Hourglass with Sorcerer's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Neeko runes against Cassiopeia?

The best Neeko runes against Cassiopeia use the Domination primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Neeko vs Cassiopeia matchup. See the full rune breakdown in the matchup comparison above.

Does Neeko counter Cassiopeia?

Yes, Neeko has a favorable matchup against Cassiopeia with a 80.0% win rate. Neeko strongly counters Cassiopeia in lane based on current patch 26.10 data.

How do I play Neeko against Cassiopeia?

When playing Neeko against Cassiopeia, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.