Zileanvs Vayne
Zilean vs Vayne is a decisive matchup in LoL patch 26.10. Zilean wins with a 66.7% win rate (+33.3%) over Vayne based on 6 games. Zilean holds the advantage in both the early and late game. Below you'll find the best Zilean build, runes, laning stats, and strategies for the Zilean vs Vayne matchup.
Zilean Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Zilean performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Vayne(66.7%)Who Wins the Zilean vs Vayne Matchup?
Zilean vs Vayne Matchup Summary
The Zilean vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 6 recent matches analyzed, Zilean wins with a 66.7% win rate compared to Vayne's 33.3%, giving Zilean a 33.3 percentage point advantage. Zilean dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Vayne players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Zilean leads by 0.8s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Zilean players can confidently pick into Vayne and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Vayne away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Zilean vs Vayne Laning Phase Breakdown
Vayne is favored during the laning phase against Zilean, winning 3 out of 5 key stat categories. Vayne holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.
Best Zilean Build Against Vayne
Ionian Boots of Lucidity is the optimal boots choice against Vayne, providing the mobility and stats Zilean needs most in this matchup. The top-performing core items for Zilean against Vayne are Mikael's Blessing, Redemption and Shurelya's Battlesong. This combination gives Zilean an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Zilean vs Vayne matchup.
Early Game vs Late Game
Zilean60.0%Vayne40.0%Zilean100.0%Vayne0.0%Zilean dominates the early game (first 15 minutes) with a commanding 60.0% win rate — a 20.0 percentage point lead over Vayne. This lopsided early game means Zilean can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Zilean is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Vayne. Extended games heavily favor Zilean, whose kit and scaling make them a dominant force in team fights and objective control.
Zilean holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Vayne players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Zilean Runes Against Vayne
Sorcery
Inspiration
Running Sorcery primary with Inspiration secondary allows Zilean to press their advantage against Vayne, amplifying the strengths that make this a favorable matchup.
Zilean matchup data for League of Legends patch 26.10. The table below shows Zilean's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Zilean build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 46.98% | 149 | 1.6 | 355 | 8,794 | 47.1% | 46.8% | |
| 45.89% | 146 | 1.5 | 351 | 8,611 | 54.0% | 39.8% | |
| 56.39% | 133 | 1.5 | 411 | 9,000 | 52.8% | 58.8% | |
| 48.76% | 121 | 1.8 | 357 | 9,016 | 47.9% | 49.3% | |
| 50.53% | 95 | 1.6 | 410 | 9,173 | 53.7% | 48.1% | |
| 50.00% | 92 | 1.4 | 384 | 9,251 | 50.0% | 50.0% | |
| 54.35% | 92 | 1.5 | 346 | 8,641 | 53.7% | 54.9% | |
| 57.32% | 82 | 1.4 | 291 | 8,443 | 54.3% | 59.6% | |
| 43.75% | 80 | 1.6 | 356 | 9,069 | 37.5% | 47.9% | |
| 49.37% | 79 | 1.5 | 376 | 8,717 | 52.5% | 46.1% | |
| 52.00% | 75 | 1.5 | 383 | 8,590 | 58.8% | 46.3% | |
| 52.05% | 73 | 1.6 | 393 | 8,912 | 48.4% | 54.8% | |
| 53.45% | 58 | 1.6 | 371 | 9,173 | 55.0% | 52.6% | |
| 38.60% | 57 | 2.3 | 389 | 8,876 | 32.0% | 43.8% | |
| 60.71% | 56 | 1.5 | 313 | 8,867 | 53.6% | 67.9% | |
| 44.23% | 52 | 1.5 | 328 | 8,319 | 41.4% | 47.8% | |
| 54.90% | 51 | 1.2 | 343 | 8,238 | 51.9% | 58.3% | |
| 56.00% | 50 | 1.5 | 359 | 8,906 | 52.6% | 58.1% | |
| 35.42% | 48 | 1.7 | 476 | 9,078 | 42.9% | 29.6% | |
| 51.06% | 47 | 1.8 | 387 | 8,966 | 47.6% | 53.9% | |
| 65.22% | 46 | 1.6 | 347 | 9,350 | 61.1% | 67.9% | |
| 67.39% | 46 | 1.9 | 466 | 9,340 | 75.0% | 61.5% | |
| 37.50% | 40 | 1.4 | 410 | 8,887 | 43.8% | 33.3% | |
| 50.00% | 38 | 1.7 | 382 | 8,137 | 63.2% | 36.8% | |
| 63.89% | 36 | 1.6 | 402 | 10,161 | 81.8% | 56.0% | |
| 66.67% | 36 | 2.3 | 381 | 8,440 | 65.0% | 68.8% | |
| 71.43% | 35 | 1.4 | 338 | 8,678 | 73.3% | 70.0% | |
| 38.71% | 31 | 1.4 | 358 | 8,026 | 37.5% | 40.0% | |
| 43.33% | 30 | 1.4 | 311 | 8,339 | 33.3% | 53.3% | |
| 44.00% | 25 | 4.2 | 496 | 10,289 | 40.0% | 46.7% | |
| 45.45% | 22 | 1.5 | 353 | 8,877 | 42.9% | 50.0% | |
| 55.00% | 20 | 1.5 | 391 | 8,829 | 60.0% | 50.0% | |
| 50.00% | 18 | 2.0 | 399 | 8,715 | 42.9% | 54.5% | |
| 38.89% | 18 | 2.2 | 394 | 9,903 | 37.5% | 40.0% | |
| 70.59% | 17 | 3.2 | 367 | 8,402 | 75.0% | 66.7% | |
| 40.00% | 15 | 2.3 | 404 | 9,340 | 33.3% | 44.4% | |
| 53.33% | 15 | 1.9 | 383 | 9,058 | 60.0% | 50.0% | |
| 57.14% | 14 | 1.2 | 387 | 8,068 | 83.3% | 37.5% | |
| 57.14% | 14 | 5.1 | 443 | 10,259 | 50.0% | 62.5% | |
| 38.46% | 13 | 3.1 | 429 | 9,719 | 40.0% | 37.5% | |
| 66.67% | 12 | 1.6 | 430 | 9,338 | 75.0% | 62.5% | |
| 58.33% | 12 | 3.2 | 469 | 10,628 | 33.3% | 66.7% | |
| 50.00% | 12 | 2.1 | 391 | 10,410 | 50.0% | 50.0% | |
| 54.55% | 11 | 2.3 | 394 | 8,724 | 60.0% | 50.0% | |
| 50.00% | 10 | 1.4 | 371 | 8,442 | 40.0% | 60.0% | |
| 22.22% | 9 | 5.9 | 391 | 7,279 | 0.0% | 50.0% | |
| 25.00% | 8 | 3.4 | 429 | 9,129 | 0.0% | 33.3% | |
| 62.50% | 8 | 1.5 | 305 | 8,902 | 100.0% | 40.0% | |
| 75.00% | 8 | 5.3 | 630 | 13,444 | 100.0% | 66.7% | |
| 50.00% | 8 | 6.0 | 586 | 10,805 | 33.3% | 60.0% | |
| 85.71% | 7 | 5.5 | 540 | 11,341 | 0.0% | 100.0% | |
| 71.43% | 7 | 4.6 | 547 | 11,904 | 0.0% | 83.3% | |
| 57.14% | 7 | 4.8 | 475 | 8,853 | 60.0% | 50.0% | |
| 57.14% | 7 | 3.3 | 431 | 9,574 | 33.3% | 75.0% | |
| 28.57% | 7 | 1.2 | 352 | 8,316 | 50.0% | 20.0% | |
| 57.14% | 7 | 1.8 | 434 | 11,346 | 50.0% | 60.0% | |
| 71.43% | 7 | 5.2 | 544 | 10,289 | 33.3% | 100.0% | |
| 71.43% | 7 | 6.1 | 458 | 9,722 | 60.0% | 100.0% | |
| 50.00% | 6 | 4.5 | 517 | 10,863 | 50.0% | 50.0% | |
| 33.33% | 6 | 2.6 | 311 | 8,474 | 66.7% | 0.0% | |
| 50.00% | 6 | 5.8 | 451 | 9,432 | 75.0% | 0.0% | |
| 50.00% | 6 | 4.0 | 580 | 8,675 | 100.0% | 25.0% | |
| 66.67% | 6 | 3.9 | 558 | 8,479 | 66.7% | 66.7% | |
| 50.00% | 6 | 5.2 | 322 | 9,706 | 33.3% | 66.7% | |
| 50.00% | 6 | 5.9 | 722 | 7,769 | 33.3% | 66.7% | |
| 50.00% | 6 | 4.0 | 409 | 7,986 | 66.7% | 33.3% | |
| 66.67% | 6 | 3.8 | 421 | 9,850 | 50.0% | 75.0% | |
| 66.67% | 6 | 4.0 | 343 | 8,527 | 60.0% | 100.0% | |
| 50.00% | 6 | 3.1 | 465 | 11,209 | 0.0% | 60.0% | |
| 80.00% | 5 | 5.6 | 572 | 11,798 | 100.0% | 66.7% | |
| 20.00% | 5 | 2.8 | 599 | 10,793 | 0.0% | 33.3% | |
| 40.00% | 5 | 1.4 | 321 | 7,829 | 33.3% | 50.0% | |
| 60.00% | 5 | 3.9 | 477 | 10,192 | 50.0% | 66.7% | |
| 60.00% | 5 | 2.5 | 399 | 10,687 | 50.0% | 66.7% | |
| 60.00% | 5 | 5.5 | 499 | 9,998 | 33.3% | 100.0% | |
| 80.00% | 5 | 5.5 | 637 | 10,932 | 100.0% | 50.0% | |
| 20.00% | 5 | 1.9 | 502 | 9,554 | 0.0% | 25.0% | |
| 80.00% | 5 | 5.3 | 623 | 11,753 | 100.0% | 66.7% | |
| 60.00% | 5 | 1.4 | 343 | 9,086 | 33.3% | 100.0% | |
| 80.00% | 5 | 3.0 | 397 | 9,568 | 66.7% | 100.0% | |
| 40.00% | 5 | 2.5 | 376 | 8,515 | 0.0% | 100.0% | |
| 20.00% | 5 | 5.8 | 635 | 12,251 | 50.0% | 0.0% | |
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Zilean vs Vayne - Frequently Asked Questions
How does Zilean do against Vayne in League of Legends?
Zilean wins the Zilean vs Vayne matchup with a 66.7% win rate compared to Vayne's 33.3%, a 33.3 percentage point difference. This data is based on 6 recent ranked games in patch 26.10.
How does Zilean do against Vayne in the early game?
In the early game, Zilean has the advantage against Vayne with a 60.0% win rate versus 40.0%. Zilean players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Zilean do against Vayne in the late game?
In the late game, Zilean takes over the Zilean vs Vayne matchup with a 100.0% win rate compared to 0.0%. Zilean scales better into team fights and objective contests after 25 minutes.
Who wins the Zilean vs Vayne matchup?
Zilean wins the matchup against Vayne with a 66.7% win rate in League of Legends patch 26.10. The 33.3 percentage point advantage means Zilean is significantly favored in this lane matchup based on 6 games analyzed.
What is the best Zilean build against Vayne?
The best Zilean build against Vayne includes Mikael's Blessing, Redemption, Shurelya's Battlesong with Ionian Boots of Lucidity. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Zilean runes against Vayne?
The best Zilean runes against Vayne use the Sorcery primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Zilean vs Vayne matchup. See the full rune breakdown in the matchup comparison above.
Does Zilean counter Vayne?
Yes, Zilean has a favorable matchup against Vayne with a 66.7% win rate. Zilean strongly counters Vayne in lane based on current patch 26.10 data.
How do I play Zilean against Vayne?
When playing Zilean against Vayne, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.