Zyra, League of Legends champion
Win Rate
51.5%
Pick Rate
2.0%
Ban Rate
4.7%

Zyra Support Runes: Keystone & Shards

Zyra B TierMageSupport
Patch
26.22
Games
1,224
Lane
Support
Tier
All Tiers
Last Updated
Nov 7, 2026 UTC
Methodology
Data Methodology

Best Support Zyra runes for LoL Patch 26.22 - Arcane Comet from the Sorcery tree with Domination secondary (52.5% WR, 23.2% pick rate). Zyra's optimal primary runes are Arcane Comet, Manaflow Band, Transcendence, Scorch. Secondary tree: Relentless Hunter, Taste of Blood.

Zyra performs best with Arcane Comet as the keystone rune from the Sorcery tree. Zyra's optimal primary runes are Arcane Comet, Manaflow Band, Transcendence, Scorch. Zyra's secondary rune tree is Domination with Relentless Hunter, Taste of Blood. This rune setup achieves a 52.46% win rate (+0.9% win rate difference) with a 23.2% pick rate across 284 Zyra games.
52.5%Win Rate
+0.9%WR Diff
23.2%Pick Rate
Arcane CometArcane Comet

Damaging a champion with an ability hurls a comet at their location, dealing increased damage based on distance.

Adaptive Damage: 15 - 100 based on level (+0.05 AP and +0.1 bonus AD)
Cooldown: 20 - 8s

Damage amplification scales up to 100% at 750 range.

Manaflow BandManaflow Band

Hitting an enemy champion with an ability permanently increases your maximum mana by 25, up to 250 mana.

After reaching 250 bonus mana, restore 1% of your missing mana every 5 seconds.

Cooldown: 15 seconds

TranscendenceTranscendence

Gain bonuses upon reaching the following levels:
Level 5: +5 Ability Haste
Level 8: +5 Ability Haste
Level 11: On Champion takedown, reduce the remaining cooldown of basic abilities by 20%.

ScorchScorch

Your next damaging ability hit sets champions on fire dealing 20 - 40 bonus magic damage based on level after 1s.

Cooldown: 10s

Relentless HunterRelentless Hunter

Gain 8 Move Speed out of combat per Bounty Hunter stack. Bounty Hunter stacks are earned the first time you get a takedown on each enemy champion.

Taste of BloodTaste of Blood

Heal when you damage an enemy champion.

Healing: 16-40 (+0.1 bonus AD, +0.05 AP) health (based on level)

Cooldown: 20s

This alternative Zyra rune build uses Electrocute as the keystone from the Domination tree. The primary runes are Electrocute, Cheap Shot, Grisly Mementos, Ultimate Hunter. Zyra's secondary rune tree is Sorcery with Manaflow Band, Transcendence. This setup achieves a 51.34% win rate (-0.2% win rate difference) with a 15.3% pick rate across 187 games.
51.3%Win Rate
-0.2%WR Diff
15.3%Pick Rate
ElectrocuteElectrocute

Hitting a champion with 3 separate attacks or abilities within 3s deals bonus adaptive damage.

Damage: 70 - 240 (+0.1 bonus AD, +0.05 AP) damage.
Cooldown: 20s

'We called them the Thunderlords, for to speak of their lightning was to invite disaster.'

Cheap ShotCheap Shot

Damaging champions with impaired movement or actions deals 10 - 45 bonus true damage (based on level).

Cooldown: 4s
Activates on damage occurring after the impairment.

Grisly MementosGrisly Mementos

Collect 1 memento on champion takedowns, up to 18 total.

Gain 6 Trinket Haste for each collected. In game modes where vision Trinkets do not exist, instead gain 3 Summoner Spell Haste.

Ultimate HunterUltimate Hunter

Your ultimate gains 6 Ability Haste, plus an additional 5 Ability Haste per Bounty Hunter stack. Bounty Hunter stacks are earned the first time you get a takedown on each enemy champion.

Manaflow BandManaflow Band

Hitting an enemy champion with an ability permanently increases your maximum mana by 25, up to 250 mana.

After reaching 250 bonus mana, restore 1% of your missing mana every 5 seconds.

Cooldown: 15 seconds

TranscendenceTranscendence

Gain bonuses upon reaching the following levels:
Level 5: +5 Ability Haste
Level 8: +5 Ability Haste
Level 11: On Champion takedown, reduce the remaining cooldown of basic abilities by 20%.

These champions share at least 4 runes with Zyra's recommended rune builds. use similar keystone and secondary runes, making them good alternatives if you enjoy Zyra's playstyle or want to learn champions with familiar rune setups.Neeko, Hwei, Anivia, Seraphine, Vel'Koz and 5 others
MetaBot Desktop

Auto-import Zyra's best runes in champ select

Turn on auto-import and MetaBot Desktop applies the highest win-rate rune page when you pick a champion, adds a MetaBot item set to your shop and sets your summoner spells, keeping your Flash slot.

  • Rune page applied on pick
  • Item set added to your shop
  • Summoners set, Flash kept
MetaBot Desktop's champ select overlay importing runes, items and summoner spells

Every Zyra Support Keystone and Secondary Tree (Patch 26.22)

1,174 games

Zyra Support runs Arcane Comet in 64% of games, with a 52.8% win rate. Domination is the usual secondary tree (47%). Standard stat shards: Adaptive Force (offense), Adaptive Force (flex), Health Scaling (defense).

Keystones

RunePlayersWin RateGames
Arcane CometArcane CometMost played63.5%52.8%746
ElectrocuteElectrocute21.6%50.0%254
Deathfire TouchDeathfire Touch7.5%60.2%88
Dark HarvestDark Harvest3.8%44.4%45

Secondary trees

RunePlayersWin RateGames
DominationDominationMost played46.5%53.1%546
SorcerySorcery24.0%49.6%282
InspirationInspiration15.2%51.4%179
PrecisionPrecision12.9%52.3%151

Pick rate is the share of Zyra games in this lane that used the rune; options under 40 games are left out. A higher win rate on a rarely picked rune is usually a matchup-specific choice, not a general upgrade.

Zyra Minor Runes by Tree

Every minor rune Zyra players take, grouped by rune tree, with how often it is picked and how often it wins.

Sorcery

RunePlayersWin RateGames
Manaflow BandManaflow BandMost played89.6%52.2%1,052
TranscendenceTranscendence87.1%52.2%1,023
ScorchScorch72.1%53.5%846
Gathering StormGathering Storm6.1%48.6%72
Absolute FocusAbsolute Focus4.3%56.0%50
Axiom ArcanistAxiom Arcanist4.0%61.7%47

Domination

RunePlayersWin RateGames
Taste of BloodTaste of BloodMost played41.4%52.5%486
Relentless HunterRelentless Hunter39.5%51.9%464
Ultimate HunterUltimate Hunter29.6%51.9%347
Cheap ShotCheap Shot29.3%50.0%344
Grisly MementosGrisly Mementos22.1%48.1%260

Inspiration

RunePlayersWin RateGames
Cosmic InsightCosmic InsightMost played13.8%48.1%162
Biscuit DeliveryBiscuit Delivery13.0%48.4%153
Magical FootwearMagical Footwear3.5%70.7%41

Precision

RunePlayersWin RateGames
Cut DownCut DownMost played8.7%53.9%102
Presence of MindPresence of Mind8.1%49.5%95
Legend: HasteLegend: Haste5.7%52.2%67

Zyra Stat Shards

Which stat shards Zyra players choose in each of the three shard rows, and the win rate of each.

RunePlayersWin RateGames
Adaptive Force (flex)Adaptive Force (flex)Most played89.9%51.3%1,056
Adaptive Force (offense)Adaptive Force (offense)84.8%51.3%995
Health Scaling (defense)Health Scaling (defense)81.4%51.0%956
Ability Haste (offense)Ability Haste (offense)13.4%56.1%157
Health (defense)Health (defense)12.9%57.9%152
Move Speed (flex)Move Speed (flex)9.1%58.9%107
Tenacity and Slow Resist (defense)Tenacity and Slow Resist (defense)5.6%53.0%66
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Zyra Runes FAQ - Patch 26.22

What is the best keystone for Zyra Support?

Arcane Comet: Zyra Support takes it in 64% of ranked games and wins 52.8% of 746 games. Alternatives: Electrocute (22%, 50.0%), Deathfire Touch (7%, 60.2%).

What stat shards should Zyra take?

Most Zyra players take Adaptive Force (offense), Adaptive Force (flex), Health Scaling (defense) — one from each shard row.

What are the best Zyra runes in patch 26.22?

The best Zyra runes in patch 26.22 use the Sorcery tree with Arcane Comet, Manaflow Band, Transcendence, and Scorch, and the Domination tree with Relentless Hunter and Taste of Blood. This rune setup achieves a 52.5% win rate with a 23.2% pick rate.

What is the win rate for Zyra's best rune page?

Zyra's best rune page has a 52.5% win rate in patch 26.22, which is +0.9% compared to Zyra's average win rate. This rune setup has a 23.2% pick rate among Zyra players.

What keystone should I use on Zyra?

Arcane Comet from the Sorcery tree is the best keystone rune for Zyra in patch 26.22. This keystone synergizes well with Zyra's kit and provides a 52.5% win rate.

What is Zyra's primary rune tree?

Zyra's primary rune tree is Sorcery. The optimal Sorcery runes for Zyra are Arcane Comet, Manaflow Band, Transcendence, and Scorch, with Arcane Comet being the keystone of choice.

What is Zyra's secondary rune tree?

Zyra's best secondary rune tree is Domination. The recommended Domination runes are Relentless Hunter and Taste of Blood, which complement Zyra's Sorcery primary tree.

What are alternative rune setups for Zyra?

An alternative Zyra rune setup uses Electrocute from the Domination tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.

How popular are Zyra's runes?

Zyra's top rune page has a 23.2% pick rate in patch 26.22. This indicates that 23.2% of Zyra players use the Arcane Comet setup with Sorcery and Domination trees.