One-Handed Path of Exile 2 game term

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What is One-Handed?

Game data Verified for 0.5.5f

One-handed weapons can be placed in the main weapon slot. Some one-handed weapon types can be dual wielded in both main and off hand weapon slots.

The game's own definition, as shown when you hover the term in game.

Game data: Path of Exile 2 client · How we source this

One-handed weapons can be placed in the main weapon slot. Some one-handed weapon types can be dual wielded in both main and off hand weapon slots.