Camille - League of Legends Champion
Win Rate
47.4%
Pick Rate
2.7%

Camillevs Vayne

FFighterAssassin
Patch26.14
Matches491,560
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 21, 2026
MethodologyData Methodology

Camille vs Vayne is a decisive matchup in LoL patch 26.14. Vayne wins with a 66.7% win rate (+33.3%) over Camille based on 6 games. Camille wins the early laning phase while Vayne scales better into the late game. Below you'll find the best Camille build, runes, laning stats, and strategies for the Camille vs Vayne matchup.

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Camille Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Camille performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Camille - 33.3% win rate in this matchup
Camille
33.3% WR
VS
Vayne vs Camille matchup - 66.7% win rate
Vayne
66.7% WR

Who Wins the Camille vs Vayne Matchup?

Vayne wins the Camille vs Vayne matchup
Winner
Vayne
Matches: 6
33.3%
Win Rate
66.7%
4.5
CS / min
5.9
615
DMG / min
979
12,802
Gold / game
16,504
268
Heal / min
283
1,274
DMG Mitigated / min
692
0.6
CC / min
0.4
0.0%
Early Game WR
0.0%
33.3%
Late Game WR
66.7%

Camille vs Vayne Matchup Summary

The Camille vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 6 recent matches analyzed, Vayne wins with a 66.7% win rate compared to Camille's 33.3%, giving Vayne a 33.3 percentage point advantage. Game phase dynamics play a critical role here: Camille controls the early laning stage, but Vayne outscales as the game goes longer. The matchup shifts dramatically depending on game length — Camille needs to press advantages before Vayne reaches their power spikes, while Vayne should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in damage output, where Vayne leads by 364 DMG/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne has a strong advantage in this matchup. Camille players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Vayne overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Camille vs Vayne Laning Phase Breakdown

Vayne wins the laning phase against Camille in League of Legends

Vayne is favored during the laning phase against Camille, winning 3 out of 5 key stat categories. Vayne holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
4.5Camille
5.9Vayne
Vayne significantly out-farms Camille by 1.4 CS per minute, accumulating an estimated 21 CS lead by mid game. This substantial farming gap gives Vayne a major gold advantage and earlier item completions. Camille players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
615Camille
979Vayne
Vayne heavily out-damages Camille by 364 DMG/min, dominating both short trades and all-in fights. Camille should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vayne's sustained damage advantage take over.
Economy
12,802Camille
16,504Vayne
Vayne generates a commanding 3,702 more gold per game than Camille. This substantial economic advantage means Vayne consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Camille should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.6Camille
0.4Vayne
Both Camille and Vayne provide similar amounts of crowd control (0.2s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
1,543Camille
976Vayne
Camille vastly out-sustains Vayne, healing and mitigating 567 more damage per minute. This massive durability gap means Camille can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Best Camille Build Against Vayne

Plated Steelcaps is the optimal boots choice against Vayne, providing the mobility and stats Camille needs most in this matchup. The top-performing core items for Camille against Vayne are Death's Dance, Trinity Force and Ravenous Hydra. This combination gives Camille an effective balance of damage, survivability, and utility for the matchup. This build achieves a solid 50.0% win rate across 2 games, proving it to be a reliable item path when facing Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Camille vs Vayne matchup.

Early Game vs Late Game

Early Game
Camille
0.0%
+0.0% advantage
Camille early game win rateCamille0.0%
Vayne early game win rateVayne0.0%
Late Game
Vayne
66.7%
+33.3% advantage
Camille late game win rateCamille33.3%
Vayne late game win rateVayne66.7%

The early game (first 15 minutes) is a toss-up between Camille and Vayne, with Camille holding a razor-thin 0.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Vayne is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Camille. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.

The power dynamics shift as the game progresses — Camille has the edge early, but Vayne gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Camille Runes Against Vayne

Precision rune tree - Camille primary runes vs VaynePrecision
Conqueror - best Camille rune vs VayneTriumph - best Camille rune vs VayneLegend: Alacrity - best Camille rune vs VayneLast Stand - best Camille rune vs Vayne
Resolve rune tree - Camille secondary runes vs VayneResolve
Bone Plating - best Camille rune vs VayneShield Bash - best Camille rune vs Vayne
66.7% WR

The Precision and Resolve rune setup gives Camille the best tools to compete against Vayne in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Camille matchup data for League of Legends patch 26.14. The table below shows Camille's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Camille build, runes, laning stats, and early vs late game analysis for that specific matchup.

Camille matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
45.14%1441.35699,44946.4%44.3%
44.04%1091.25809,73157.9%36.6%
39.19%741.25668,79731.3%45.2%
53.62%691.26309,72965.5%45.0%
44.78%671.25739,67746.9%42.9%
42.42%661.359510,25458.1%28.6%
54.10%616.691211,92451.9%55.9%
52.46%611.26609,77954.3%50.0%
45.61%571.46169,22253.3%37.0%
43.14%512.274310,24431.6%50.0%
46.94%492.66429,80950.0%45.2%
53.19%472.372211,14462.5%48.4%
42.22%451.15898,90044.0%40.0%
59.09%441.35708,97668.2%50.0%
35.71%425.782910,84625.0%45.5%
51.22%414.671910,23253.3%50.0%
52.50%401.26038,35660.0%45.0%
53.85%391.558910,25258.3%51.9%
26.32%381.35568,25026.3%26.3%
45.95%375.694711,71146.7%45.5%
63.89%361.262610,37062.5%64.3%
33.33%361.46689,95240.0%28.6%
52.94%341.35639,25850.0%55.6%
48.48%335.778311,30637.5%58.8%
51.52%334.081111,60540.0%56.5%
41.94%311.26478,94146.1%38.9%
26.67%305.571910,37529.4%23.1%
43.33%301.467710,68044.4%42.9%
53.33%305.880710,47342.9%62.5%
58.62%291.162410,44554.5%61.1%
51.72%291.26309,50142.9%60.0%
39.29%284.364710,09446.1%33.3%
55.56%271.25989,38154.5%56.3%
50.00%265.987710,28556.3%40.0%
38.46%261.663710,62528.6%42.1%
26.92%265.484610,71530.0%25.0%
44.00%255.682611,30266.7%36.8%
36.00%255.493110,90220.0%46.7%
48.00%251.46149,79440.0%53.3%
44.00%256.086312,07162.5%35.3%
25.00%241.05537,53333.3%11.1%
58.33%241.276911,13042.9%64.7%
30.43%235.59649,50733.3%28.6%
30.43%231.361010,15242.9%25.0%
52.17%235.881212,13240.0%61.5%
47.83%231.465210,04133.3%57.1%
36.36%225.578910,22727.3%45.5%
54.55%221.25998,81950.0%58.3%
40.91%226.31,17712,32957.1%33.3%
42.86%211.464110,32042.9%42.9%
70.00%205.91,00811,41540.0%100.0%
55.00%205.775411,16337.5%66.7%
40.00%205.387911,44642.9%38.5%
26.32%191.36749,22014.3%33.3%
26.32%195.58098,3210.0%71.4%
68.75%161.36829,10971.4%66.7%
66.67%156.173811,35066.7%66.7%
46.67%151.45819,57250.0%44.4%
66.67%155.889511,31466.7%66.7%
42.86%144.79099,94937.5%50.0%
42.86%146.08499,59840.0%44.4%
42.86%145.393910,61250.0%33.3%
42.86%141.15488,97766.7%25.0%
53.85%136.597611,38257.1%50.0%
33.33%125.782810,44366.7%0.0%
50.00%125.777710,78475.0%37.5%
41.67%126.398511,04314.3%80.0%
66.67%125.054911,77850.0%75.0%
58.33%124.383112,15233.3%66.7%
58.33%127.597812,19633.3%83.3%
72.73%116.177910,79360.0%83.3%
30.00%106.090013,2730.0%42.9%
55.56%95.28979,90933.3%66.7%
44.44%92.272111,6230.0%57.1%
55.56%95.41,02913,6840.0%55.6%
55.56%91.35988,33366.7%50.0%
55.56%95.776710,40975.0%40.0%
44.44%92.280911,38750.0%40.0%
37.50%82.573111,25750.0%33.3%
62.50%81.16657,94066.7%50.0%
75.00%86.385114,170100.0%71.4%
25.00%85.072010,79366.7%0.0%
50.00%85.61,03614,698100.0%42.9%
37.50%86.086210,46340.0%33.3%
57.14%73.063510,08360.0%50.0%
71.43%73.56668,52180.0%50.0%
42.86%73.59229,62950.0%33.3%
66.67%62.37009,39250.0%75.0%
33.33%64.561512,8020.0%33.3%
50.00%66.465010,48566.7%33.3%
83.33%62.388013,692100.0%66.7%
50.00%61.26739,92366.7%33.3%
33.33%65.982110,99540.0%0.0%
20.00%55.175510,9970.0%25.0%
100.00%52.895211,258100.0%100.0%
80.00%55.455111,201100.0%75.0%
40.00%53.377811,9300.0%50.0%
60.00%53.096813,844100.0%33.3%
60.00%51.265411,0470.0%75.0%
20.00%53.095813,185100.0%0.0%
40.00%53.55026,39640.0%0.0%
0.00%51.17038,6410.0%0.0%

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Camille vs Vayne - Frequently Asked Questions

How does Camille do against Vayne in League of Legends?

Vayne wins the Camille vs Vayne matchup with a 66.7% win rate compared to Camille's 33.3%, a 33.3 percentage point difference. This data is based on 6 recent ranked games in patch 26.14.

How does Camille do against Vayne in the early game?

In the early game, Camille has the advantage against Vayne with a 0.0% win rate versus 0.0%. Camille players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Camille do against Vayne in the late game?

In the late game, Vayne takes over the Camille vs Vayne matchup with a 66.7% win rate compared to 33.3%. Vayne scales better into team fights and objective contests after 25 minutes.

Who wins the Camille vs Vayne matchup?

Vayne wins the matchup against Camille with a 66.7% win rate in League of Legends patch 26.14. The 33.3 percentage point advantage means Vayne is significantly favored in this lane matchup based on 6 games analyzed.

What is the best Camille build against Vayne?

The best Camille build against Vayne includes Death's Dance, Trinity Force, Ravenous Hydra with Plated Steelcaps. This build achieves a 50.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Camille runes against Vayne?

The best Camille runes against Vayne use the Precision primary tree with Resolve secondary. This rune setup achieves a 66.7% win rate in the Camille vs Vayne matchup. See the full rune breakdown in the matchup comparison above.

Does Camille counter Vayne?

No, Camille struggles against Vayne with only a 33.3% win rate. Vayne has the advantage in this matchup. Camille players should focus on safe farming and avoiding extended trades to minimize Vayne's lead.

How do I play Camille against Vayne?

When playing Camille against Vayne, play cautiously and avoid Vayne's power spikes. Look for jungle assistance and team-dependent plays since Vayne has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.