Camille - League of Legends Champion
Win Rate
49.9%
Pick Rate
1.3%

Camillevs Vayne

CFighterAssassin
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 20, 2026
MethodologyData Methodology

Camille vs Vayne is a decisive matchup in LoL patch 26.7. Vayne wins with a 70.0% win rate (+40.0%) over Camille based on 10 games. Vayne holds the advantage in both the early and late game. Below you'll find the best Camille build, runes, laning stats, and strategies for the Camille vs Vayne matchup.

Camille Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Camille performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vayne - 30.0% win rateVayne(30.0%)
Camille - 30.0% win rate in this matchup
Camille
30.0% WR
VS
Vayne vs Camille matchup - 70.0% win rate
Vayne
70.0% WR

Who Wins the Camille vs Vayne Matchup?

Vayne wins the Camille vs Vayne matchup
Winner
Vayne
Matches: 10
30.0%
Win Rate
70.0%
6.0
CS / min
6.6
865
DMG / min
996
13,159
Gold / game
13,490
321
Heal / min
266
1,215
DMG Mitigated / min
626
0.8
CC / min
0.4
25.0%
Early Game WR
75.0%
33.3%
Late Game WR
66.7%

Camille vs Vayne Matchup Summary

The Camille vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 10 recent matches analyzed, Vayne wins with a 70.0% win rate compared to Camille's 30.0%, giving Vayne a 40.0 percentage point advantage. Vayne dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Camille players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Camille leads by 0.4s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne has a strong advantage in this matchup. Camille players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Vayne overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Camille vs Vayne Laning Phase Breakdown

Vayne wins the laning phase against Camille in League of Legends

Vayne is favored during the laning phase against Camille, winning 3 out of 5 key stat categories. Vayne holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
6.0Camille
6.6Vayne
Vayne edges out Camille by 0.6 CS per minute — a moderate farming advantage that adds up to roughly 10 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Vayne.
Damage
865Camille
996Vayne
Vayne heavily out-damages Camille by 131 DMG/min, dominating both short trades and all-in fights. Camille should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vayne's sustained damage advantage take over.
Economy
13,159Camille
13,490Vayne
Vayne earns 331 more gold per game than Camille, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Vayne slightly faster item completions.
Utility
0.8Camille
0.4Vayne
Camille provides 0.4 seconds more crowd control per minute than Vayne, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Camille coordinate with their jungler and control the pace of skirmishes.
Sustain
1,535Camille
892Vayne
Camille vastly out-sustains Vayne, healing and mitigating 643 more damage per minute. This massive durability gap means Camille can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Best Camille Build Against Vayne

Mercury's Treads is the optimal boots choice against Vayne, providing the mobility and stats Camille needs most in this matchup. The top-performing core items for Camille against Vayne are Death's Dance, Spear of Shojin and Trinity Force. This combination gives Camille an effective balance of damage, survivability, and utility for the matchup. This build has a 33.3% win rate across 3 games. While the overall matchup may be difficult, this item path gives Camille the best chance to compete against Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Camille vs Vayne matchup.

Early Game vs Late Game

Early Game
Vayne
75.0%
+50.0% advantage
Camille early game win rateCamille25.0%
Vayne early game win rateVayne75.0%
Late Game
Vayne
66.7%
+33.3% advantage
Camille late game win rateCamille33.3%
Vayne late game win rateVayne66.7%

Vayne dominates the early game (first 15 minutes) with a commanding 75.0% win rate — a 50.0 percentage point lead over Camille. This lopsided early game means Vayne can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Vayne is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Camille. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.

Vayne holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Camille players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Camille Runes Against Vayne

Resolve rune tree - Camille primary runes vs VayneResolve
Grasp of the Undying - best Camille rune vs VayneShield Bash - best Camille rune vs VayneSecond Wind - best Camille rune vs VayneRevitalize - best Camille rune vs Vayne
Inspiration rune tree - Camille secondary runes vs VayneInspiration
Magical Footwear - best Camille rune vs VayneBiscuit Delivery - best Camille rune vs Vayne
100.0% WR

The Resolve and Inspiration rune setup gives Camille the best tools to compete against Vayne in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Camille matchup data for League of Legends patch 26.7. The table below shows Camille's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Camille build, runes, laning stats, and early vs late game analysis for that specific matchup.

Camille matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
48.92%1396.792012,20757.6%41.1%
44.00%506.075011,11836.0%52.0%
54.55%446.497812,14845.8%65.0%
40.00%406.283111,25747.6%31.6%
47.37%385.983011,42547.4%47.4%
55.56%365.687412,70469.2%47.8%
45.45%335.493411,92941.2%50.0%
59.38%326.370010,96863.2%53.9%
58.06%316.490612,53263.6%55.0%
41.38%296.195312,17850.0%36.8%
37.93%296.21,02312,73833.3%40.0%
48.00%256.41,01412,26150.0%46.1%
32.00%256.790512,88011.1%43.8%
58.33%246.387612,80855.6%60.0%
50.00%246.487013,42850.0%50.0%
52.17%236.382411,70945.5%58.3%
65.22%236.51,03813,51660.0%69.2%
36.36%225.979310,18840.0%33.3%
47.62%215.780612,99033.3%53.3%
60.00%206.785612,16750.0%64.3%
70.00%206.585612,83742.9%84.6%
55.00%206.51,09511,13956.3%50.0%
52.63%195.081011,18345.5%62.5%
36.84%196.385211,23950.0%22.2%
55.56%186.484111,37266.7%44.4%
61.11%185.561210,56766.7%55.6%
23.53%176.91,09715,17925.0%23.1%
41.18%176.186112,04030.0%57.1%
70.59%176.292712,10771.4%70.0%
56.25%166.790512,7610.0%75.0%
66.67%157.11,01613,962100.0%44.4%
33.33%156.51,17113,16033.3%33.3%
60.00%156.483411,25250.0%71.4%
28.57%146.361810,57927.3%33.3%
28.57%146.31,53511,51742.9%14.3%
57.14%146.31,05213,67340.0%66.7%
46.15%136.681413,28042.9%50.0%
38.46%136.792712,26037.5%40.0%
50.00%125.987313,19450.0%50.0%
50.00%126.07389,30150.0%50.0%
36.36%111.264810,18316.7%60.0%
50.00%106.586410,99350.0%50.0%
30.00%106.086513,15925.0%33.3%
66.67%95.27268,66057.1%100.0%
22.22%96.056010,45425.0%20.0%
37.50%85.687011,3690.0%50.0%
71.43%76.080611,50466.7%75.0%
42.86%75.37568,21133.3%50.0%
28.57%71.058010,93650.0%20.0%
28.57%75.393810,34325.0%33.3%
83.33%66.91,00714,08666.7%100.0%
50.00%61.96139,55260.0%0.0%
33.33%61.066410,5140.0%50.0%
50.00%66.595915,722100.0%40.0%
66.67%61.65648,66175.0%50.0%
50.00%65.979313,1440.0%60.0%
16.67%64.76188,7630.0%50.0%
33.33%62.460813,2060.0%33.3%
80.00%55.287514,356100.0%66.7%
60.00%55.883513,475100.0%50.0%
60.00%52.264712,111100.0%50.0%
40.00%51.251811,6160.0%50.0%
20.00%56.27928,6170.0%50.0%
20.00%51.14308,52733.3%0.0%
40.00%51.566910,6380.0%50.0%

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Camille vs Vayne - Frequently Asked Questions

How does Camille do against Vayne in League of Legends?

Vayne wins the Camille vs Vayne matchup with a 70.0% win rate compared to Camille's 30.0%, a 40.0 percentage point difference. This data is based on 10 recent ranked games in patch 26.7.

How does Camille do against Vayne in the early game?

In the early game, Vayne has the advantage against Camille with a 75.0% win rate versus 25.0%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Camille do against Vayne in the late game?

In the late game, Vayne takes over the Camille vs Vayne matchup with a 66.7% win rate compared to 33.3%. Vayne scales better into team fights and objective contests after 25 minutes.

Who wins the Camille vs Vayne matchup?

Vayne wins the matchup against Camille with a 70.0% win rate in League of Legends patch 26.7. The 40.0 percentage point advantage means Vayne is significantly favored in this lane matchup based on 10 games analyzed.

What is the best Camille build against Vayne?

The best Camille build against Vayne includes Death's Dance, Spear of Shojin, Trinity Force with Mercury's Treads. This build achieves a 33.3% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Camille runes against Vayne?

The best Camille runes against Vayne use the Resolve primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Camille vs Vayne matchup. See the full rune breakdown in the matchup comparison above.

Does Camille counter Vayne?

No, Camille struggles against Vayne with only a 30.0% win rate. Vayne has the advantage in this matchup. Camille players should focus on safe farming and avoiding extended trades to minimize Vayne's lead.

How do I play Camille against Vayne?

When playing Camille against Vayne, play cautiously and avoid Vayne's power spikes. Look for jungle assistance and team-dependent plays since Vayne has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.