Camille - League of Legends Champion
Win Rate
49.5%
Pick Rate
1.3%

Camillevs Vayne

CFighterAssassin
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 6, 2026
MethodologyData Methodology

Camille vs Vayne is a decisive matchup in LoL patch 26.11. Camille wins with a 53.3% win rate (+6.7%) over Vayne based on 15 games. Camille holds the advantage in both the early and late game. Below you'll find the best Camille build, runes, laning stats, and strategies for the Camille vs Vayne matchup.

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Camille Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Camille performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Camille - 53.3% win rate in this matchup
Camille
53.3% WR
VS
Vayne vs Camille matchup - 46.7% win rate
Vayne
46.7% WR

Who Wins the Camille vs Vayne Matchup?

Camille wins the Camille vs Vayne matchup
Winner
Camille
Matches: 15
53.3%
Win Rate
46.7%
5.4
CS / min
6.6
692
DMG / min
876
10,378
Gold / game
11,530
217
Heal / min
235
1,035
DMG Mitigated / min
493
0.6
CC / min
0.4
50.0%
Early Game WR
50.0%
57.1%
Late Game WR
42.9%

Camille vs Vayne Matchup Summary

The Camille vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 15 recent matches analyzed, Camille wins with a 53.3% win rate compared to Vayne's 46.7%, giving Camille a 6.7 percentage point advantage. Camille dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Vayne players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Camille leads by 525 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Camille players can confidently pick into Vayne and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Vayne away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Camille vs Vayne Laning Phase Breakdown

Vayne wins the laning phase against Camille in League of Legends

Vayne is favored during the laning phase against Camille, winning 3 out of 5 key stat categories. Vayne holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
5.4Camille
6.6Vayne
Vayne significantly out-farms Camille by 1.1 CS per minute, accumulating an estimated 17 CS lead by mid game. This substantial farming gap gives Vayne a major gold advantage and earlier item completions. Camille players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
692Camille
876Vayne
Vayne heavily out-damages Camille by 184 DMG/min, dominating both short trades and all-in fights. Camille should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vayne's sustained damage advantage take over.
Economy
10,378Camille
11,530Vayne
Vayne generates a commanding 1,151 more gold per game than Camille. This substantial economic advantage means Vayne consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Camille should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.6Camille
0.4Vayne
Both Camille and Vayne provide similar amounts of crowd control (0.2s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
1,253Camille
728Vayne
Camille vastly out-sustains Vayne, healing and mitigating 525 more damage per minute. This massive durability gap means Camille can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Best Camille Build Against Vayne

Mercury's Treads is the optimal boots choice against Vayne, providing the mobility and stats Camille needs most in this matchup. The top-performing core items for Camille against Vayne are Trinity Force, Ravenous Hydra and Sterak's Gage. This combination gives Camille an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 2 games — well above average and making it the top item path against Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Camille vs Vayne matchup.

Early Game vs Late Game

Early Game
Camille
50.0%
+0.0% advantage
Camille early game win rateCamille50.0%
Vayne early game win rateVayne50.0%
Late Game
Camille
57.1%
+14.3% advantage
Camille late game win rateCamille57.1%
Vayne late game win rateVayne42.9%

The early game (first 15 minutes) is a toss-up between Camille and Vayne, with Camille holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Camille is far superior in the late game (25+ minutes), boasting a 57.1% win rate — 14.3 points above Vayne. Extended games heavily favor Camille, whose kit and scaling make them a dominant force in team fights and objective control.

Camille holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Vayne players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Camille Runes Against Vayne

Resolve rune tree - Camille primary runes vs VayneResolve
Grasp of the Undying - best Camille rune vs VayneShield Bash - best Camille rune vs VayneSecond Wind - best Camille rune vs VayneOvergrowth - best Camille rune vs Vayne
Inspiration rune tree - Camille secondary runes vs VayneInspiration
Biscuit Delivery - best Camille rune vs VayneMagical Footwear - best Camille rune vs Vayne
100.0% WR

Running Resolve primary with Inspiration secondary allows Camille to press their advantage against Vayne, amplifying the strengths that make this a favorable matchup.


Camille matchup data for League of Legends patch 26.11. The table below shows Camille's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Camille build, runes, laning stats, and early vs late game analysis for that specific matchup.

Camille matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
50.44%1136.596512,38943.5%55.2%
49.15%596.177311,19741.2%60.0%
56.25%485.878111,87350.0%59.4%
44.68%476.278011,49845.0%44.4%
48.78%415.774811,14031.3%60.0%
51.22%416.21,00412,66742.1%59.1%
37.50%405.587511,83129.4%43.5%
39.47%386.187211,32040.0%38.9%
47.37%385.467110,19737.5%54.5%
59.46%375.892311,56866.7%52.6%
55.88%346.789810,69463.6%41.7%
58.06%316.182511,79264.3%52.9%
43.33%306.088311,34938.9%50.0%
53.33%306.079211,23042.9%62.5%
31.03%296.494412,99830.0%31.6%
34.48%295.871610,97831.3%38.5%
53.57%286.288810,44538.5%66.7%
57.14%286.595912,80041.7%68.8%
46.43%286.31,09112,54160.0%38.9%
42.86%286.880411,53840.0%46.1%
33.33%276.01,22512,51236.4%31.3%
37.04%271.667011,26737.5%36.8%
38.46%266.196412,78550.0%28.6%
50.00%265.586311,59650.0%50.0%
36.00%256.098612,63057.1%27.8%
60.87%236.21,04712,70072.7%50.0%
34.78%236.282310,81446.1%20.0%
34.78%231.16959,71736.4%33.3%
54.55%225.979811,90454.5%54.5%
45.45%226.31,00812,46460.0%33.3%
59.09%226.593112,80255.6%61.5%
45.45%227.084613,83625.0%57.1%
47.62%214.881612,90125.0%61.5%
52.38%216.197212,29680.0%43.8%
52.63%194.785011,86250.0%54.5%
57.89%193.686711,74763.6%50.0%
42.11%196.394412,34022.2%60.0%
68.42%196.691612,50375.0%63.6%
63.16%196.678811,37870.0%55.6%
38.89%186.492713,00050.0%33.3%
47.06%176.392613,61850.0%46.1%
62.50%161.256211,08975.0%58.3%
31.25%161.857711,9950.0%38.5%
46.67%151.882610,56362.5%28.6%
46.67%154.082413,04440.0%50.0%
40.00%152.05739,58836.4%50.0%
53.33%155.880713,10857.1%50.0%
40.00%151.25478,10940.0%40.0%
53.33%155.469210,37850.0%57.1%
35.71%145.078310,81925.0%50.0%
53.85%136.598112,51660.0%50.0%
38.46%135.567211,60040.0%37.5%
38.46%134.377612,30820.0%50.0%
46.15%131.861810,65660.0%37.5%
50.00%125.875414,22366.7%44.4%
75.00%126.882611,565100.0%0.0%
33.33%121.876011,9900.0%57.1%
45.45%111.459010,25366.7%20.0%
54.55%116.582812,37860.0%50.0%
45.45%111.25228,93750.0%33.3%
40.00%101.15359,08640.0%40.0%
40.00%105.362510,79925.0%50.0%
60.00%102.15989,92875.0%50.0%
70.00%105.796511,17060.0%80.0%
40.00%104.371112,34450.0%25.0%
60.00%105.784912,51233.3%71.4%
33.33%95.572111,16125.0%40.0%
33.33%92.05118,58350.0%20.0%
66.67%91.46488,80566.7%66.7%
33.33%91.15178,82550.0%20.0%
44.44%94.372211,90233.3%50.0%
44.44%91.25597,27780.0%0.0%
66.67%91.361410,09966.7%66.7%
37.50%82.26229,95140.0%33.3%
12.50%81.275210,6970.0%20.0%
62.50%86.191211,91783.3%0.0%
62.50%84.05438,57750.0%75.0%
62.50%84.065912,93666.7%60.0%
62.50%82.893812,855100.0%50.0%
62.50%85.05988,88760.0%66.7%
0.00%70.94849,9990.0%0.0%
57.14%71.15778,781100.0%25.0%
42.86%74.689815,5310.0%50.0%
83.33%62.679013,06166.7%100.0%
100.00%62.279312,810100.0%100.0%
50.00%65.873810,88066.7%33.3%
66.67%66.864413,632100.0%60.0%
66.67%62.095515,912100.0%60.0%
100.00%61.964810,706100.0%100.0%
60.00%50.979011,57050.0%100.0%
40.00%53.176610,3920.0%66.7%
40.00%54.387810,14766.7%0.0%
60.00%54.287115,8460.0%60.0%
60.00%52.81,00412,113100.0%50.0%
20.00%50.95078,2020.0%100.0%
60.00%54.863712,18766.7%50.0%
40.00%53.973111,84450.0%33.3%
60.00%53.373713,602100.0%50.0%
40.00%52.46419,88950.0%33.3%

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Camille vs Vayne - Frequently Asked Questions

How does Camille do against Vayne in League of Legends?

Camille wins the Camille vs Vayne matchup with a 53.3% win rate compared to Vayne's 46.7%, a 6.7 percentage point difference. This data is based on 15 recent ranked games in patch 26.11.

How does Camille do against Vayne in the early game?

In the early game, Camille has the advantage against Vayne with a 50.0% win rate versus 50.0%. Camille players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Camille do against Vayne in the late game?

In the late game, Camille takes over the Camille vs Vayne matchup with a 57.1% win rate compared to 42.9%. Camille scales better into team fights and objective contests after 25 minutes.

Who wins the Camille vs Vayne matchup?

Camille wins the matchup against Vayne with a 53.3% win rate in League of Legends patch 26.11. The 6.7 percentage point advantage means Camille is significantly favored in this lane matchup based on 15 games analyzed.

What is the best Camille build against Vayne?

The best Camille build against Vayne includes Trinity Force, Ravenous Hydra, Sterak's Gage with Mercury's Treads. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Camille runes against Vayne?

The best Camille runes against Vayne use the Resolve primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Camille vs Vayne matchup. See the full rune breakdown in the matchup comparison above.

Does Camille counter Vayne?

Yes, Camille has a favorable matchup against Vayne with a 53.3% win rate. Camille strongly counters Vayne in lane based on current patch 26.11 data.

How do I play Camille against Vayne?

When playing Camille against Vayne, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.