
Camillevs Vayne
Camille vs Vayne is a decisive matchup in LoL patch 26.11. Camille wins with a 53.3% win rate (+6.7%) over Vayne based on 15 games. Camille holds the advantage in both the early and late game. Below you'll find the best Camille build, runes, laning stats, and strategies for the Camille vs Vayne matchup.
Camille Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Camille performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Camille vs Vayne Matchup?

Camille vs Vayne Matchup Summary
The Camille vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 15 recent matches analyzed, Camille wins with a 53.3% win rate compared to Vayne's 46.7%, giving Camille a 6.7 percentage point advantage. Camille dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Vayne players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Camille leads by 525 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Camille players can confidently pick into Vayne and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Vayne away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Camille vs Vayne Laning Phase Breakdown
Vayne is favored during the laning phase against Camille, winning 3 out of 5 key stat categories. Vayne holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.
Best Camille Build Against Vayne
Mercury's Treads is the optimal boots choice against Vayne, providing the mobility and stats Camille needs most in this matchup. The top-performing core items for Camille against Vayne are Trinity Force, Ravenous Hydra and Sterak's Gage. This combination gives Camille an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 2 games — well above average and making it the top item path against Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Camille vs Vayne matchup.
Early Game vs Late Game
The early game (first 15 minutes) is a toss-up between Camille and Vayne, with Camille holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.
Camille is far superior in the late game (25+ minutes), boasting a 57.1% win rate — 14.3 points above Vayne. Extended games heavily favor Camille, whose kit and scaling make them a dominant force in team fights and objective control.
Camille holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Vayne players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Camille Runes Against Vayne
Running Resolve primary with Inspiration secondary allows Camille to press their advantage against Vayne, amplifying the strengths that make this a favorable matchup.
Camille matchup data for League of Legends patch 26.11. The table below shows Camille's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Camille build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 50.44% | 113 | 6.5 | 965 | 12,389 | 43.5% | 55.2% | |
| 49.15% | 59 | 6.1 | 773 | 11,197 | 41.2% | 60.0% | |
| 56.25% | 48 | 5.8 | 781 | 11,873 | 50.0% | 59.4% | |
| 44.68% | 47 | 6.2 | 780 | 11,498 | 45.0% | 44.4% | |
| 48.78% | 41 | 5.7 | 748 | 11,140 | 31.3% | 60.0% | |
| 51.22% | 41 | 6.2 | 1,004 | 12,667 | 42.1% | 59.1% | |
| 37.50% | 40 | 5.5 | 875 | 11,831 | 29.4% | 43.5% | |
| 39.47% | 38 | 6.1 | 872 | 11,320 | 40.0% | 38.9% | |
| 47.37% | 38 | 5.4 | 671 | 10,197 | 37.5% | 54.5% | |
| 59.46% | 37 | 5.8 | 923 | 11,568 | 66.7% | 52.6% | |
| 55.88% | 34 | 6.7 | 898 | 10,694 | 63.6% | 41.7% | |
| 58.06% | 31 | 6.1 | 825 | 11,792 | 64.3% | 52.9% | |
| 43.33% | 30 | 6.0 | 883 | 11,349 | 38.9% | 50.0% | |
| 53.33% | 30 | 6.0 | 792 | 11,230 | 42.9% | 62.5% | |
| 31.03% | 29 | 6.4 | 944 | 12,998 | 30.0% | 31.6% | |
| 34.48% | 29 | 5.8 | 716 | 10,978 | 31.3% | 38.5% | |
| 53.57% | 28 | 6.2 | 888 | 10,445 | 38.5% | 66.7% | |
| 57.14% | 28 | 6.5 | 959 | 12,800 | 41.7% | 68.8% | |
| 46.43% | 28 | 6.3 | 1,091 | 12,541 | 60.0% | 38.9% | |
| 42.86% | 28 | 6.8 | 804 | 11,538 | 40.0% | 46.1% | |
| 33.33% | 27 | 6.0 | 1,225 | 12,512 | 36.4% | 31.3% | |
| 37.04% | 27 | 1.6 | 670 | 11,267 | 37.5% | 36.8% | |
| 38.46% | 26 | 6.1 | 964 | 12,785 | 50.0% | 28.6% | |
| 50.00% | 26 | 5.5 | 863 | 11,596 | 50.0% | 50.0% | |
| 36.00% | 25 | 6.0 | 986 | 12,630 | 57.1% | 27.8% | |
| 60.87% | 23 | 6.2 | 1,047 | 12,700 | 72.7% | 50.0% | |
| 34.78% | 23 | 6.2 | 823 | 10,814 | 46.1% | 20.0% | |
| 34.78% | 23 | 1.1 | 695 | 9,717 | 36.4% | 33.3% | |
| 54.55% | 22 | 5.9 | 798 | 11,904 | 54.5% | 54.5% | |
| 45.45% | 22 | 6.3 | 1,008 | 12,464 | 60.0% | 33.3% | |
| 59.09% | 22 | 6.5 | 931 | 12,802 | 55.6% | 61.5% | |
| 45.45% | 22 | 7.0 | 846 | 13,836 | 25.0% | 57.1% | |
| 47.62% | 21 | 4.8 | 816 | 12,901 | 25.0% | 61.5% | |
| 52.38% | 21 | 6.1 | 972 | 12,296 | 80.0% | 43.8% | |
| 52.63% | 19 | 4.7 | 850 | 11,862 | 50.0% | 54.5% | |
| 57.89% | 19 | 3.6 | 867 | 11,747 | 63.6% | 50.0% | |
| 42.11% | 19 | 6.3 | 944 | 12,340 | 22.2% | 60.0% | |
| 68.42% | 19 | 6.6 | 916 | 12,503 | 75.0% | 63.6% | |
| 63.16% | 19 | 6.6 | 788 | 11,378 | 70.0% | 55.6% | |
| 38.89% | 18 | 6.4 | 927 | 13,000 | 50.0% | 33.3% | |
| 47.06% | 17 | 6.3 | 926 | 13,618 | 50.0% | 46.1% | |
| 62.50% | 16 | 1.2 | 562 | 11,089 | 75.0% | 58.3% | |
| 31.25% | 16 | 1.8 | 577 | 11,995 | 0.0% | 38.5% | |
| 46.67% | 15 | 1.8 | 826 | 10,563 | 62.5% | 28.6% | |
| 46.67% | 15 | 4.0 | 824 | 13,044 | 40.0% | 50.0% | |
| 40.00% | 15 | 2.0 | 573 | 9,588 | 36.4% | 50.0% | |
| 53.33% | 15 | 5.8 | 807 | 13,108 | 57.1% | 50.0% | |
| 40.00% | 15 | 1.2 | 547 | 8,109 | 40.0% | 40.0% | |
| 53.33% | 15 | 5.4 | 692 | 10,378 | 50.0% | 57.1% | |
| 35.71% | 14 | 5.0 | 783 | 10,819 | 25.0% | 50.0% | |
| 53.85% | 13 | 6.5 | 981 | 12,516 | 60.0% | 50.0% | |
| 38.46% | 13 | 5.5 | 672 | 11,600 | 40.0% | 37.5% | |
| 38.46% | 13 | 4.3 | 776 | 12,308 | 20.0% | 50.0% | |
| 46.15% | 13 | 1.8 | 618 | 10,656 | 60.0% | 37.5% | |
| 50.00% | 12 | 5.8 | 754 | 14,223 | 66.7% | 44.4% | |
| 75.00% | 12 | 6.8 | 826 | 11,565 | 100.0% | 0.0% | |
| 33.33% | 12 | 1.8 | 760 | 11,990 | 0.0% | 57.1% | |
| 45.45% | 11 | 1.4 | 590 | 10,253 | 66.7% | 20.0% | |
| 54.55% | 11 | 6.5 | 828 | 12,378 | 60.0% | 50.0% | |
| 45.45% | 11 | 1.2 | 522 | 8,937 | 50.0% | 33.3% | |
| 40.00% | 10 | 1.1 | 535 | 9,086 | 40.0% | 40.0% | |
| 40.00% | 10 | 5.3 | 625 | 10,799 | 25.0% | 50.0% | |
| 60.00% | 10 | 2.1 | 598 | 9,928 | 75.0% | 50.0% | |
| 70.00% | 10 | 5.7 | 965 | 11,170 | 60.0% | 80.0% | |
| 40.00% | 10 | 4.3 | 711 | 12,344 | 50.0% | 25.0% | |
| 60.00% | 10 | 5.7 | 849 | 12,512 | 33.3% | 71.4% | |
| 33.33% | 9 | 5.5 | 721 | 11,161 | 25.0% | 40.0% | |
| 33.33% | 9 | 2.0 | 511 | 8,583 | 50.0% | 20.0% | |
| 66.67% | 9 | 1.4 | 648 | 8,805 | 66.7% | 66.7% | |
| 33.33% | 9 | 1.1 | 517 | 8,825 | 50.0% | 20.0% | |
| 44.44% | 9 | 4.3 | 722 | 11,902 | 33.3% | 50.0% | |
| 44.44% | 9 | 1.2 | 559 | 7,277 | 80.0% | 0.0% | |
| 66.67% | 9 | 1.3 | 614 | 10,099 | 66.7% | 66.7% | |
| 37.50% | 8 | 2.2 | 622 | 9,951 | 40.0% | 33.3% | |
| 12.50% | 8 | 1.2 | 752 | 10,697 | 0.0% | 20.0% | |
| 62.50% | 8 | 6.1 | 912 | 11,917 | 83.3% | 0.0% | |
| 62.50% | 8 | 4.0 | 543 | 8,577 | 50.0% | 75.0% | |
| 62.50% | 8 | 4.0 | 659 | 12,936 | 66.7% | 60.0% | |
| 62.50% | 8 | 2.8 | 938 | 12,855 | 100.0% | 50.0% | |
| 62.50% | 8 | 5.0 | 598 | 8,887 | 60.0% | 66.7% | |
| 0.00% | 7 | 0.9 | 484 | 9,999 | 0.0% | 0.0% | |
| 57.14% | 7 | 1.1 | 577 | 8,781 | 100.0% | 25.0% | |
| 42.86% | 7 | 4.6 | 898 | 15,531 | 0.0% | 50.0% | |
| 83.33% | 6 | 2.6 | 790 | 13,061 | 66.7% | 100.0% | |
| 100.00% | 6 | 2.2 | 793 | 12,810 | 100.0% | 100.0% | |
| 50.00% | 6 | 5.8 | 738 | 10,880 | 66.7% | 33.3% | |
| 66.67% | 6 | 6.8 | 644 | 13,632 | 100.0% | 60.0% | |
| 66.67% | 6 | 2.0 | 955 | 15,912 | 100.0% | 60.0% | |
| 100.00% | 6 | 1.9 | 648 | 10,706 | 100.0% | 100.0% | |
| 60.00% | 5 | 0.9 | 790 | 11,570 | 50.0% | 100.0% | |
| 40.00% | 5 | 3.1 | 766 | 10,392 | 0.0% | 66.7% | |
| 40.00% | 5 | 4.3 | 878 | 10,147 | 66.7% | 0.0% | |
| 60.00% | 5 | 4.2 | 871 | 15,846 | 0.0% | 60.0% | |
| 60.00% | 5 | 2.8 | 1,004 | 12,113 | 100.0% | 50.0% | |
| 20.00% | 5 | 0.9 | 507 | 8,202 | 0.0% | 100.0% | |
| 60.00% | 5 | 4.8 | 637 | 12,187 | 66.7% | 50.0% | |
| 40.00% | 5 | 3.9 | 731 | 11,844 | 50.0% | 33.3% | |
| 60.00% | 5 | 3.3 | 737 | 13,602 | 100.0% | 50.0% | |
| 40.00% | 5 | 2.4 | 641 | 9,889 | 50.0% | 33.3% | |
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Camille vs Vayne - Frequently Asked Questions
How does Camille do against Vayne in League of Legends?
Camille wins the Camille vs Vayne matchup with a 53.3% win rate compared to Vayne's 46.7%, a 6.7 percentage point difference. This data is based on 15 recent ranked games in patch 26.11.
How does Camille do against Vayne in the early game?
In the early game, Camille has the advantage against Vayne with a 50.0% win rate versus 50.0%. Camille players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Camille do against Vayne in the late game?
In the late game, Camille takes over the Camille vs Vayne matchup with a 57.1% win rate compared to 42.9%. Camille scales better into team fights and objective contests after 25 minutes.
Who wins the Camille vs Vayne matchup?
Camille wins the matchup against Vayne with a 53.3% win rate in League of Legends patch 26.11. The 6.7 percentage point advantage means Camille is significantly favored in this lane matchup based on 15 games analyzed.
What is the best Camille build against Vayne?
The best Camille build against Vayne includes Trinity Force, Ravenous Hydra, Sterak's Gage with Mercury's Treads. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Camille runes against Vayne?
The best Camille runes against Vayne use the Resolve primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Camille vs Vayne matchup. See the full rune breakdown in the matchup comparison above.
Does Camille counter Vayne?
Yes, Camille has a favorable matchup against Vayne with a 53.3% win rate. Camille strongly counters Vayne in lane based on current patch 26.11 data.
How do I play Camille against Vayne?
When playing Camille against Vayne, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.
