Vayne - League of Legends Champion
Win Rate
50.4%
Pick Rate
4.9%

Vaynevs Camille

BMarksmanAssassin
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 5, 2026
MethodologyData Methodology

Vayne vs Camille is a decisive matchup in LoL patch 26.11. Camille wins with a 53.3% win rate (+6.7%) over Vayne based on 15 games. Vayne wins the early laning phase while Camille scales better into the late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Camille matchup.

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Vayne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vayne - 46.7% win rate in this matchup
Vayne
46.7% WR
VS
Camille vs Vayne matchup - 53.3% win rate
Camille
53.3% WR

Who Wins the Vayne vs Camille Matchup?

Camille wins the Vayne vs Camille matchup
Winner
Camille
Matches: 15
46.7%
Win Rate
53.3%
6.6
CS / min
5.4
876
DMG / min
692
11,530
Gold / game
10,378
235
Heal / min
217
493
DMG Mitigated / min
1,035
0.4
CC / min
0.6
50.0%
Early Game WR
50.0%
42.9%
Late Game WR
57.1%

Vayne vs Camille Matchup Summary

The Vayne vs Camille matchup is a decisive matchup in League of Legends ranked play. Based on 15 recent matches analyzed, Camille wins with a 53.3% win rate compared to Vayne's 46.7%, giving Camille a 6.7 percentage point advantage. Game phase dynamics play a critical role here: Vayne controls the early laning stage, but Camille outscales as the game goes longer. The matchup shifts dramatically depending on game length — Vayne needs to press advantages before Camille reaches their power spikes, while Camille should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Camille leads by 525 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Camille has a strong advantage in this matchup. Vayne players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Camille overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vayne vs Camille Laning Phase Breakdown

Vayne wins the laning phase against Camille in League of Legends

Vayne is favored during the laning phase against Camille, winning 3 out of 5 key stat categories. Vayne holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
6.6Vayne
5.4Camille
Vayne significantly out-farms Camille by 1.1 CS per minute, accumulating an estimated 17 CS lead by mid game. This substantial farming gap gives Vayne a major gold advantage and earlier item completions. Camille players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
876Vayne
692Camille
Vayne heavily out-damages Camille by 184 DMG/min, dominating both short trades and all-in fights. Camille should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vayne's sustained damage advantage take over.
Economy
11,530Vayne
10,378Camille
Vayne generates a commanding 1,151 more gold per game than Camille. This substantial economic advantage means Vayne consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Camille should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.4Vayne
0.6Camille
Both Vayne and Camille provide similar amounts of crowd control (0.2s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
728Vayne
1,253Camille
Camille vastly out-sustains Vayne, healing and mitigating 525 more damage per minute. This massive durability gap means Camille can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Best Vayne Build Against Camille

Berserker's Greaves is the optimal boots choice against Camille, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Camille are Essence Reaver, Stormrazor and Experimental Hexplate. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Camille matchup.

Early Game vs Late Game

Early Game
Vayne
50.0%
+0.0% advantage
Vayne early game win rateVayne50.0%
Camille early game win rateCamille50.0%
Late Game
Camille
57.1%
+14.3% advantage
Vayne late game win rateVayne42.9%
Camille late game win rateCamille57.1%

The early game (first 15 minutes) is a toss-up between Vayne and Camille, with Vayne holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Camille is far superior in the late game (25+ minutes), boasting a 57.1% win rate — 14.3 points above Vayne. Extended games heavily favor Camille, whose kit and scaling make them a dominant force in team fights and objective control.

The power dynamics shift as the game progresses — Vayne has the edge early, but Camille gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Vayne Runes Against Camille

Precision rune tree - Vayne primary runes vs CamillePrecision
Lethal Tempo - best Vayne rune vs CamilleTriumph - best Vayne rune vs CamilleLegend: Bloodline - best Vayne rune vs CamilleLast Stand - best Vayne rune vs Camille
Sorcery rune tree - Vayne secondary runes vs CamilleSorcery
Celerity - best Vayne rune vs CamilleManaflow Band - best Vayne rune vs Camille
100.0% WR

The Precision and Sorcery rune setup gives Vayne the best tools to compete against Camille in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Vayne matchup data for League of Legends patch 26.11. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vayne matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
46.01%4766.078912,87544.3%47.4%
47.20%4476.079112,72545.4%48.6%
46.26%4285.779612,71544.9%47.3%
53.92%3956.085712,96853.2%54.6%
47.85%3726.289413,18946.8%48.6%
52.99%3516.284313,14252.5%53.4%
52.98%2856.390413,45646.2%58.8%
53.90%2696.387713,73748.2%58.0%
52.38%1895.988612,46846.1%58.2%
51.92%1566.591311,98950.0%53.4%
54.30%1516.185913,22758.5%51.2%
50.33%1516.180413,00743.8%55.2%
45.95%1485.978013,60345.3%46.3%
45.38%1306.177613,08138.2%50.7%
47.83%1156.481213,76538.5%52.6%
42.61%1156.178112,08234.0%49.2%
50.88%1145.886612,98941.2%58.7%
45.19%1046.489913,17548.7%43.1%
59.80%1026.585413,18963.5%56.0%
31.00%1005.563510,36011.1%47.3%
45.83%965.885713,16444.4%46.7%
50.53%956.31,12012,73751.6%50.0%
58.06%936.379613,00854.8%60.8%
44.09%935.862511,33042.4%45.0%
45.56%905.883011,35543.6%47.1%
45.98%876.385113,57237.9%50.0%
55.81%866.189910,74843.2%65.3%
55.95%846.21,29211,54651.4%59.2%
56.41%786.388313,43557.1%55.8%
54.84%625.981412,06158.3%52.6%
45.76%596.287712,77548.0%44.1%
51.92%526.091311,59248.1%56.0%
45.10%516.592112,14440.9%48.3%
52.00%506.087513,62147.8%55.6%
35.42%486.272110,98228.0%43.5%
58.33%486.198911,81064.0%52.2%
45.83%486.21,00510,83851.9%38.1%
50.00%466.297013,36447.4%51.9%
58.70%466.291413,67162.5%54.5%
54.55%446.287414,06357.1%53.3%
44.19%436.683913,74455.0%34.8%
26.19%425.987411,67823.5%28.0%
48.78%415.983611,64443.5%55.6%
52.50%405.683813,60737.5%56.3%
38.46%396.785410,96150.0%28.6%
41.03%396.07439,57128.6%55.6%
67.57%376.589811,52662.5%76.9%
45.95%375.683211,99840.0%50.0%
52.94%346.475912,24550.0%54.5%
52.94%346.41,05111,47452.6%53.3%
66.67%336.393813,52461.5%70.0%
48.48%336.478411,26950.0%46.1%
48.48%336.597913,30562.5%44.0%
40.63%325.382011,34442.1%38.5%
62.50%325.779613,16341.7%75.0%
40.63%326.267610,36931.6%53.9%
58.06%316.484912,13864.3%52.9%
53.33%305.685512,15255.6%52.4%
60.00%306.095312,30876.9%47.1%
43.33%306.664611,44137.5%50.0%
55.56%275.379211,00650.0%60.0%
48.15%276.283411,46543.8%54.5%
50.00%265.969311,80141.7%57.1%
50.00%266.171011,42146.1%53.9%
30.77%265.370011,00127.3%33.3%
50.00%265.883412,30154.5%46.7%
48.00%256.081612,91020.0%66.7%
44.00%256.475811,84450.0%38.5%
54.17%246.399112,32564.3%40.0%
45.83%246.085011,12557.1%30.0%
56.52%235.761010,29945.5%66.7%
45.45%226.573412,18438.5%55.6%
40.91%226.080612,81544.4%38.5%
42.11%196.292010,37245.5%37.5%
63.16%196.387012,58950.0%72.7%
42.11%195.881712,14257.1%33.3%
61.11%185.61,00813,43366.7%58.3%
62.50%166.188511,54762.5%62.5%
80.00%152.288517,36850.0%84.6%
53.33%156.498513,30150.0%54.5%
60.00%156.583311,24437.5%85.7%
46.67%156.687611,53050.0%42.9%
46.67%155.491613,99225.0%54.5%
42.86%146.482413,96675.0%30.0%
42.86%146.084113,4470.0%66.7%
53.85%136.584913,506100.0%33.3%
46.15%135.275011,57950.0%42.9%
66.67%125.61,02512,92880.0%57.1%
33.33%126.092711,90033.3%33.3%
54.55%115.61,00213,29850.0%57.1%
63.64%116.164210,20450.0%80.0%
54.55%112.982014,06866.7%40.0%
81.82%116.277512,783100.0%71.4%
54.55%113.484613,74333.3%62.5%
54.55%115.576111,64971.4%25.0%
45.45%115.69159,80875.0%28.6%
40.00%104.670811,73250.0%25.0%
60.00%105.782012,59750.0%62.5%
50.00%103.877113,23733.3%57.1%
40.00%105.592611,89340.0%40.0%
66.67%93.81,03913,79866.7%66.7%
33.33%96.11,07613,2730.0%50.0%
55.56%96.793013,145100.0%20.0%
33.33%96.085513,01833.3%33.3%
55.56%93.986012,86033.3%66.7%
50.00%85.887014,56550.0%50.0%
62.50%87.368411,84766.7%50.0%
50.00%83.288313,47975.0%25.0%
25.00%85.26909,10216.7%50.0%
37.50%85.85269,89450.0%25.0%
57.14%74.076010,75033.3%75.0%
71.43%73.674311,42580.0%50.0%
42.86%74.572311,69733.3%50.0%
28.57%74.567612,0460.0%40.0%
50.00%63.578115,0220.0%60.0%
33.33%66.882313,7790.0%50.0%
33.33%62.998912,89833.3%33.3%
66.67%65.91,00614,14350.0%75.0%
20.00%54.75778,99933.3%0.0%
40.00%52.161112,29050.0%0.0%
40.00%56.41,17614,5940.0%50.0%
80.00%56.21,02413,762100.0%66.7%
40.00%55.996213,2480.0%50.0%
40.00%56.06739,21850.0%0.0%
40.00%56.47269,89240.0%0.0%

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Vayne vs Camille - Frequently Asked Questions

How does Vayne do against Camille in League of Legends?

Camille wins the Vayne vs Camille matchup with a 53.3% win rate compared to Vayne's 46.7%, a 6.7 percentage point difference. This data is based on 15 recent ranked games in patch 26.11.

How does Vayne do against Camille in the early game?

In the early game, Vayne has the advantage against Camille with a 50.0% win rate versus 50.0%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vayne do against Camille in the late game?

In the late game, Camille takes over the Vayne vs Camille matchup with a 57.1% win rate compared to 42.9%. Camille scales better into team fights and objective contests after 25 minutes.

Who wins the Vayne vs Camille matchup?

Camille wins the matchup against Vayne with a 53.3% win rate in League of Legends patch 26.11. The 6.7 percentage point advantage means Camille is significantly favored in this lane matchup based on 15 games analyzed.

What is the best Vayne build against Camille?

The best Vayne build against Camille includes Essence Reaver, Stormrazor, Experimental Hexplate with Berserker's Greaves. Check the matchup breakdown above for the full item path and build order.

What are the best Vayne runes against Camille?

The best Vayne runes against Camille use the Precision primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Camille matchup. See the full rune breakdown in the matchup comparison above.

Does Vayne counter Camille?

No, Vayne struggles against Camille with only a 46.7% win rate. Camille has the advantage in this matchup. Vayne players should focus on safe farming and avoiding extended trades to minimize Camille's lead.

How do I play Vayne against Camille?

When playing Vayne against Camille, play cautiously and avoid Camille's power spikes. Look for jungle assistance and team-dependent plays since Camille has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.