Vayne - League of Legends Champion
Win Rate
49.5%
Pick Rate
5.3%

Vaynevs Camille

DMarksmanAssassin
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 20, 2026
MethodologyData Methodology

Vayne vs Camille is a decisive matchup in LoL patch 26.7. Vayne wins with a 70.0% win rate (+40.0%) over Camille based on 10 games. Vayne holds the advantage in both the early and late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Camille matchup.

Vayne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Camille - 70.0% win rateCamille(70.0%)
Vayne - 70.0% win rate in this matchup
Vayne
70.0% WR
VS
Camille vs Vayne matchup - 30.0% win rate
Camille
30.0% WR

Who Wins the Vayne vs Camille Matchup?

Vayne wins the Vayne vs Camille matchup
Winner
Vayne
Matches: 10
70.0%
Win Rate
30.0%
6.6
CS / min
6.0
996
DMG / min
865
13,490
Gold / game
13,159
266
Heal / min
321
626
DMG Mitigated / min
1,215
0.4
CC / min
0.8
75.0%
Early Game WR
25.0%
66.7%
Late Game WR
33.3%

Vayne vs Camille Matchup Summary

The Vayne vs Camille matchup is a decisive matchup in League of Legends ranked play. Based on 10 recent matches analyzed, Vayne wins with a 70.0% win rate compared to Camille's 30.0%, giving Vayne a 40.0 percentage point advantage. Vayne dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Camille players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Camille leads by 0.4s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne players can confidently pick into Camille and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Camille away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vayne vs Camille Laning Phase Breakdown

Vayne wins the laning phase against Camille in League of Legends

Vayne is favored during the laning phase against Camille, winning 3 out of 5 key stat categories. Vayne holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
6.6Vayne
6.0Camille
Vayne edges out Camille by 0.6 CS per minute — a moderate farming advantage that adds up to roughly 10 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Vayne.
Damage
996Vayne
865Camille
Vayne heavily out-damages Camille by 131 DMG/min, dominating both short trades and all-in fights. Camille should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vayne's sustained damage advantage take over.
Economy
13,490Vayne
13,159Camille
Vayne earns 331 more gold per game than Camille, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Vayne slightly faster item completions.
Utility
0.4Vayne
0.8Camille
Camille provides 0.4 seconds more crowd control per minute than Vayne, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Camille coordinate with their jungler and control the pace of skirmishes.
Sustain
892Vayne
1,535Camille
Camille vastly out-sustains Vayne, healing and mitigating 643 more damage per minute. This massive durability gap means Camille can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Best Vayne Build Against Camille

Plated Steelcaps is the optimal boots choice against Camille, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Camille are Blade of The Ruined King, Guinsoo's Rageblade and Experimental Hexplate. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. This build achieves a solid 50.0% win rate across 2 games, proving it to be a reliable item path when facing Camille. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Camille matchup.

Early Game vs Late Game

Early Game
Vayne
75.0%
+50.0% advantage
Vayne early game win rateVayne75.0%
Camille early game win rateCamille25.0%
Late Game
Vayne
66.7%
+33.3% advantage
Vayne late game win rateVayne66.7%
Camille late game win rateCamille33.3%

Vayne dominates the early game (first 15 minutes) with a commanding 75.0% win rate — a 50.0 percentage point lead over Camille. This lopsided early game means Vayne can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Vayne is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Camille. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.

Vayne holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Camille players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Vayne Runes Against Camille

Precision rune tree - Vayne primary runes vs CamillePrecision
Lethal Tempo - best Vayne rune vs CamilleTriumph - best Vayne rune vs CamilleLegend: Alacrity - best Vayne rune vs CamilleCoup de Grace - best Vayne rune vs Camille
Inspiration rune tree - Vayne secondary runes vs CamilleInspiration
Cash Back - best Vayne rune vs CamilleJack Of All Trades - best Vayne rune vs Camille
100.0% WR

Running Precision primary with Inspiration secondary allows Vayne to press their advantage against Camille, amplifying the strengths that make this a favorable matchup.


Vayne matchup data for League of Legends patch 26.7. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vayne matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
49.02%3576.081713,23145.3%52.0%
52.47%3246.289813,59649.3%55.2%
48.09%3146.283212,81944.0%52.7%
49.01%3025.982512,93747.5%50.3%
52.94%2726.083913,07152.8%53.1%
45.37%2276.496014,25446.9%44.2%
50.00%2226.493713,71750.0%50.0%
52.71%2036.585613,74148.9%56.0%
52.32%1516.582813,28755.4%49.4%
58.39%1496.695312,70051.6%63.5%
51.30%1155.881313,71761.5%42.9%
47.71%1096.088213,23938.2%57.4%
55.67%976.488012,62559.6%51.1%
51.55%976.380612,73552.5%50.0%
50.00%945.983213,59546.7%53.1%
36.36%886.279012,98330.0%41.7%
47.44%786.692813,28446.3%48.6%
61.33%756.692412,10266.7%55.6%
55.56%726.185813,24745.2%63.4%
57.35%686.085313,57456.0%58.1%
36.76%686.288112,39436.7%36.8%
52.54%596.383712,51848.5%57.7%
42.37%596.287012,82834.4%51.9%
38.60%575.760511,22540.0%37.0%
37.50%565.560110,77030.4%42.4%
43.40%536.21,04512,46744.4%42.3%
44.00%506.188613,06147.8%40.7%
53.06%496.11,21413,80450.0%55.2%
65.91%446.186913,29266.7%65.4%
56.82%445.692114,04761.1%53.9%
43.18%445.799611,54831.3%50.0%
50.00%406.384813,58435.3%60.9%
55.00%405.989314,58823.1%70.4%
57.50%406.395114,24860.0%56.7%
48.72%396.595213,49157.9%40.0%
57.89%386.01,02912,41355.0%61.1%
42.11%386.192313,74144.4%40.0%
54.05%377.092811,69252.4%56.3%
40.54%375.880412,22541.2%40.0%
40.00%355.71,14111,80838.9%41.2%
55.88%346.585611,12557.9%53.3%
50.00%326.098613,59966.7%43.5%
66.67%306.289612,54050.0%81.3%
56.67%306.298113,89653.9%58.8%
48.28%296.785812,18028.6%66.7%
55.17%296.31,02413,69462.5%46.1%
51.85%275.798412,39145.5%56.3%
61.54%266.185111,71961.5%61.5%
64.00%256.080811,77055.6%68.8%
44.00%256.892712,26342.9%45.5%
33.33%246.483511,60541.7%25.0%
56.52%235.592112,42462.5%53.3%
43.48%236.383712,92160.0%30.8%
40.91%226.678811,10141.7%40.0%
52.38%215.992313,47740.0%63.6%
60.00%205.290914,35220.0%73.3%
47.37%196.91,00811,89263.6%25.0%
50.00%186.273213,04560.0%37.5%
50.00%186.21,05312,78455.6%44.4%
44.44%186.483711,79542.9%45.5%
50.00%185.875412,37328.6%63.6%
76.47%176.91,02114,29680.0%75.0%
29.41%176.982911,89737.5%22.2%
41.18%176.086215,19160.0%33.3%
43.75%166.083811,77362.5%25.0%
56.25%166.690711,52757.1%55.6%
37.50%165.465913,20816.7%50.0%
68.75%166.793713,92583.3%60.0%
53.33%155.968611,41937.5%71.4%
73.33%156.485112,62177.8%66.7%
50.00%145.785111,11416.7%75.0%
42.86%144.364512,05114.3%71.4%
53.85%133.388514,16275.0%44.4%
53.85%135.71,05513,76250.0%55.6%
58.33%125.656210,02757.1%60.0%
25.00%124.586213,08325.0%25.0%
50.00%126.378413,32833.3%66.7%
27.27%116.277113,46233.3%25.0%
63.64%116.387415,82666.7%62.5%
36.36%116.665110,70650.0%20.0%
45.45%115.591912,62950.0%40.0%
72.73%116.474510,85071.4%75.0%
45.45%116.01,06414,50840.0%50.0%
70.00%106.699613,49075.0%66.7%
40.00%106.887613,21633.3%50.0%
55.56%96.393712,28633.3%100.0%
44.44%96.21,07715,702100.0%28.6%
33.33%96.877411,06920.0%50.0%
25.00%85.569310,37825.0%25.0%
50.00%85.99738,78533.3%100.0%
37.50%81.983414,72733.3%40.0%
42.86%75.690112,809100.0%20.0%
0.00%76.655810,7000.0%0.0%
42.86%74.665114,53850.0%40.0%
71.43%76.168213,12675.0%66.7%
57.14%75.588812,31625.0%100.0%
57.14%75.489512,10050.0%66.7%
42.86%74.077311,64333.3%50.0%
57.14%72.51,31315,57625.0%100.0%
33.33%64.65709,10525.0%50.0%
66.67%65.91,08915,49350.0%75.0%
50.00%65.776213,18250.0%50.0%
50.00%61.989114,832100.0%40.0%
16.67%65.384410,4420.0%33.3%
0.00%65.979510,7240.0%0.0%
83.33%66.196311,361100.0%50.0%
50.00%66.380413,574100.0%40.0%
40.00%54.793914,778100.0%0.0%
60.00%51.71,19517,6480.0%75.0%
20.00%51.56919,37833.3%0.0%
60.00%55.31,10015,380100.0%50.0%
20.00%56.891512,5530.0%33.3%
40.00%56.51,02117,6030.0%40.0%

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Vayne vs Camille - Frequently Asked Questions

How does Vayne do against Camille in League of Legends?

Vayne wins the Vayne vs Camille matchup with a 70.0% win rate compared to Camille's 30.0%, a 40.0 percentage point difference. This data is based on 10 recent ranked games in patch 26.7.

How does Vayne do against Camille in the early game?

In the early game, Vayne has the advantage against Camille with a 75.0% win rate versus 25.0%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vayne do against Camille in the late game?

In the late game, Vayne takes over the Vayne vs Camille matchup with a 66.7% win rate compared to 33.3%. Vayne scales better into team fights and objective contests after 25 minutes.

Who wins the Vayne vs Camille matchup?

Vayne wins the matchup against Camille with a 70.0% win rate in League of Legends patch 26.7. The 40.0 percentage point advantage means Vayne is significantly favored in this lane matchup based on 10 games analyzed.

What is the best Vayne build against Camille?

The best Vayne build against Camille includes Blade of The Ruined King, Guinsoo's Rageblade, Experimental Hexplate with Plated Steelcaps. This build achieves a 50.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Vayne runes against Camille?

The best Vayne runes against Camille use the Precision primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Camille matchup. See the full rune breakdown in the matchup comparison above.

Does Vayne counter Camille?

Yes, Vayne has a favorable matchup against Camille with a 70.0% win rate. Vayne strongly counters Camille in lane based on current patch 26.7 data.

How do I play Vayne against Camille?

When playing Vayne against Camille, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.