Vayne - League of Legends Champion
Win Rate
50.1%
Pick Rate
4.8%

Vaynevs Camille

CMarksmanAssassin
Patch26.14
Matches491,560
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 21, 2026
MethodologyData Methodology

Vayne vs Camille is a decisive matchup in LoL patch 26.14. Vayne wins with a 66.7% win rate (+33.3%) over Camille based on 6 games. Vayne holds the advantage in both the early and late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Camille matchup.

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Vayne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vayne - 66.7% win rate in this matchup
Vayne
66.7% WR
VS
Camille vs Vayne matchup - 33.3% win rate
Camille
33.3% WR

Who Wins the Vayne vs Camille Matchup?

Vayne wins the Vayne vs Camille matchup
Winner
Vayne
Matches: 6
66.7%
Win Rate
33.3%
5.9
CS / min
4.5
979
DMG / min
615
16,504
Gold / game
12,802
283
Heal / min
268
692
DMG Mitigated / min
1,274
0.4
CC / min
0.6
0.0%
Early Game WR
0.0%
66.7%
Late Game WR
33.3%

Vayne vs Camille Matchup Summary

The Vayne vs Camille matchup is a decisive matchup in League of Legends ranked play. Based on 6 recent matches analyzed, Vayne wins with a 66.7% win rate compared to Camille's 33.3%, giving Vayne a 33.3 percentage point advantage. Vayne dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Camille players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in damage output, where Vayne leads by 364 DMG/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne players can confidently pick into Camille and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Camille away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vayne vs Camille Laning Phase Breakdown

Vayne wins the laning phase against Camille in League of Legends

Vayne is favored during the laning phase against Camille, winning 3 out of 5 key stat categories. Vayne holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
5.9Vayne
4.5Camille
Vayne significantly out-farms Camille by 1.4 CS per minute, accumulating an estimated 21 CS lead by mid game. This substantial farming gap gives Vayne a major gold advantage and earlier item completions. Camille players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
979Vayne
615Camille
Vayne heavily out-damages Camille by 364 DMG/min, dominating both short trades and all-in fights. Camille should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vayne's sustained damage advantage take over.
Economy
16,504Vayne
12,802Camille
Vayne generates a commanding 3,702 more gold per game than Camille. This substantial economic advantage means Vayne consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Camille should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.4Vayne
0.6Camille
Both Vayne and Camille provide similar amounts of crowd control (0.2s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
976Vayne
1,543Camille
Camille vastly out-sustains Vayne, healing and mitigating 567 more damage per minute. This massive durability gap means Camille can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Best Vayne Build Against Camille

Boots of Swiftness is the optimal boots choice against Camille, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Camille are Terminus, Blade of The Ruined King and Phantom Dancer. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Camille. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Camille matchup.

Early Game vs Late Game

Early Game
Vayne
0.0%
+0.0% advantage
Vayne early game win rateVayne0.0%
Camille early game win rateCamille0.0%
Late Game
Vayne
66.7%
+33.3% advantage
Vayne late game win rateVayne66.7%
Camille late game win rateCamille33.3%

The early game (first 15 minutes) is a toss-up between Vayne and Camille, with Vayne holding a razor-thin 0.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Vayne is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Camille. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.

Vayne holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Camille players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Vayne Runes Against Camille

Precision rune tree - Vayne primary runes vs CamillePrecision
Press the Attack - best Vayne rune vs CamilleTriumph - best Vayne rune vs CamilleLegend: Alacrity - best Vayne rune vs CamilleCoup de Grace - best Vayne rune vs Camille
Resolve rune tree - Vayne secondary runes vs CamilleResolve
Conditioning - best Vayne rune vs CamilleOvergrowth - best Vayne rune vs Camille
50.0% WR

Running Precision primary with Resolve secondary allows Vayne to press their advantage against Camille, amplifying the strengths that make this a favorable matchup.


Vayne matchup data for League of Legends patch 26.14. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vayne matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
48.56%3485.884712,97944.1%50.9%
53.42%3075.983912,94048.8%56.6%
48.20%2786.183613,47041.3%51.6%
47.74%2436.286012,61047.6%47.9%
53.08%2116.387812,62143.0%61.0%
41.53%1836.177312,60338.8%43.1%
52.78%1446.179112,82955.8%51.1%
51.91%1316.488114,08340.9%57.5%
41.41%1286.189212,80238.3%43.2%
49.00%1006.395213,52845.7%50.8%
42.86%986.082513,13140.0%44.1%
52.75%916.289012,27555.1%50.0%
50.00%885.772712,17443.8%53.6%
51.81%836.191011,36254.5%50.0%
47.50%806.182012,47545.7%48.9%
60.00%656.097412,77468.2%55.8%
50.00%646.084711,77746.1%52.6%
62.50%646.189912,62366.7%58.8%
33.33%605.769810,50028.6%37.5%
64.91%576.11,04212,26760.0%68.8%
50.88%576.178712,25354.8%46.1%
53.57%565.872512,48543.5%60.6%
47.17%536.472112,52633.3%58.6%
45.28%535.774511,42548.1%42.3%
40.38%526.080712,80542.9%38.7%
52.00%505.675710,82771.4%37.9%
24.00%505.559310,36710.5%32.3%
50.00%486.380412,29937.5%62.5%
43.48%465.983113,24640.0%46.1%
64.44%456.61,35613,35552.9%71.4%
44.19%436.578312,29642.9%45.5%
48.78%416.287913,46428.6%59.3%
52.94%346.789613,04850.0%55.6%
63.64%336.51,11612,11253.3%72.2%
62.50%326.381912,63145.5%71.4%
59.38%326.185412,12688.9%47.8%
38.71%315.71,02511,46427.3%45.0%
54.84%315.882011,57820.0%71.4%
67.74%316.01,05512,46354.5%75.0%
43.33%306.287912,49536.4%47.4%
53.33%306.51,29614,35044.4%57.1%
42.86%285.983212,55236.4%47.1%
66.67%276.389310,71269.2%64.3%
62.96%276.31,01010,80457.1%69.2%
51.85%276.682711,71960.0%47.1%
40.00%255.91,07612,66655.6%31.3%
66.67%246.385111,36875.0%58.3%
41.67%246.598211,95853.9%27.3%
39.13%235.380811,11011.1%57.1%
43.48%235.990312,03940.0%44.4%
52.17%236.371612,15850.0%53.3%
50.00%226.378612,37350.0%50.0%
50.00%226.387711,26933.3%61.5%
54.55%226.194413,47650.0%56.3%
50.00%225.785710,86766.7%38.5%
61.90%215.780711,32255.6%66.7%
38.10%216.188512,47866.7%26.7%
47.62%216.379414,04633.3%50.0%
40.00%206.189612,75940.0%40.0%
68.42%196.195110,33575.0%63.6%
57.89%196.381312,24550.0%63.6%
50.00%185.893811,87355.6%44.4%
70.59%176.41,04113,11580.0%66.7%
56.25%166.581114,11950.0%58.3%
43.75%165.673311,69628.6%55.6%
31.25%166.073811,87840.0%27.3%
62.50%166.294612,97250.0%70.0%
46.67%156.06619,61655.6%33.3%
66.67%156.293814,61825.0%81.8%
78.57%146.891815,770100.0%70.0%
35.71%146.29069,94233.3%37.5%
71.43%146.484613,11242.9%100.0%
64.29%146.11,14912,06157.1%71.4%
53.85%135.981013,10933.3%60.0%
53.85%135.41,01713,23150.0%57.1%
53.85%135.875710,86575.0%20.0%
50.00%126.389413,15325.0%62.5%
58.33%126.586310,15833.3%83.3%
41.67%124.489010,67950.0%25.0%
54.55%115.776412,34433.3%62.5%
50.00%106.483812,06366.7%42.9%
80.00%106.084712,029100.0%66.7%
33.33%95.072312,6860.0%50.0%
22.22%94.078213,4440.0%33.3%
66.67%94.388214,962100.0%62.5%
77.78%95.579215,017100.0%71.4%
25.00%86.486611,04250.0%0.0%
37.50%84.578011,84250.0%33.3%
12.50%84.482311,95525.0%0.0%
71.43%76.479513,70250.0%80.0%
42.86%74.852210,75633.3%50.0%
33.33%66.082514,1640.0%40.0%
50.00%63.246210,33966.7%33.3%
16.67%65.193311,15633.3%0.0%
50.00%64.07398,97350.0%50.0%
50.00%63.16307,38350.0%50.0%
83.33%65.571814,890100.0%80.0%
66.67%65.997916,5040.0%66.7%
16.67%64.784611,2830.0%25.0%
40.00%50.751211,18333.3%50.0%
0.00%55.782210,6000.0%0.0%
60.00%56.979212,10050.0%66.7%
60.00%54.298815,3860.0%60.0%
40.00%54.57149,28266.7%0.0%

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Vayne vs Camille - Frequently Asked Questions

How does Vayne do against Camille in League of Legends?

Vayne wins the Vayne vs Camille matchup with a 66.7% win rate compared to Camille's 33.3%, a 33.3 percentage point difference. This data is based on 6 recent ranked games in patch 26.14.

How does Vayne do against Camille in the early game?

In the early game, Vayne has the advantage against Camille with a 0.0% win rate versus 0.0%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vayne do against Camille in the late game?

In the late game, Vayne takes over the Vayne vs Camille matchup with a 66.7% win rate compared to 33.3%. Vayne scales better into team fights and objective contests after 25 minutes.

Who wins the Vayne vs Camille matchup?

Vayne wins the matchup against Camille with a 66.7% win rate in League of Legends patch 26.14. The 33.3 percentage point advantage means Vayne is significantly favored in this lane matchup based on 6 games analyzed.

What is the best Vayne build against Camille?

The best Vayne build against Camille includes Terminus, Blade of The Ruined King, Phantom Dancer with Boots of Swiftness. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Vayne runes against Camille?

The best Vayne runes against Camille use the Precision primary tree with Resolve secondary. This rune setup achieves a 50.0% win rate in the Vayne vs Camille matchup. See the full rune breakdown in the matchup comparison above.

Does Vayne counter Camille?

Yes, Vayne has a favorable matchup against Camille with a 66.7% win rate. Vayne strongly counters Camille in lane based on current patch 26.14 data.

How do I play Vayne against Camille?

When playing Vayne against Camille, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.