Cassiopeia Runes
Best Cassiopeia runes for LoL Patch 26.1 - Conqueror from the Precision tree with Sorcery secondary (66.7% WR, 1.6% pick rate). Cassiopeia's optimal primary runes are Conqueror, Presence of Mind, Legend: Haste, Last Stand. Secondary tree: Manaflow Band, Celerity.
Serpentine Grace
All Move Speed bonuses are more effective on Cassiopeia.
Noxious Blast
Cassiopeia blasts an area with Poison after a brief delay, granting her increased Move Speed if she hits an enemy champion.
Cost:- 50/
- 55/
- 60/
- 65/
- 70
Cooldown:- 4
Range:- 850
Miasma
Cassiopeia releases several clouds of poison, slowing, grounding, and lightly damaging enemies that pass through them. Grounded enemies cannot use Movement abilities.
Cost:- 70/
- 75/
- 80/
- 85/
- 90
Cooldown:- 24/
- 22/
- 20/
- 18/
- 16
Range:- 700
Twin Fang
Cassiopeia lets loose an attack that deals increased damage to Poisoned targets and heals her for a percentage of the damage dealt. If the target dies from this attack, Cassiopeia regains Mana.
Cost:- 40
Cooldown:- 1
Range:- 700
Petrifying Gaze
Cassiopeia releases a swirl of magical energy from her eyes, stunning any enemies in front of her that are facing her and slowing any others with their back turned.
Cost:- 100
Cooldown:- 120/
- 100/
- 80
Range:- 825
- Mage
Cassiopeia performs best with Conqueror as the keystone rune from the Precision tree. Cassiopeia's optimal primary runes are Conqueror, Presence of Mind, Legend: Haste, Last Stand. Cassiopeia's secondary rune tree is Sorcery with Manaflow Band, Celerity. This rune setup achieves a 66.67% win rate (+16.7% win rate difference) with a 1.6% pick rate across 21 Cassiopeia games.
Primary Tree
Precision
ConquerorBasic attacks or spells that deal damage to an enemy champion grant 2 stacks of Conqueror for 5s, gaining 1.8-4
When fully stacked, heal for 8% of the damage you deal to champions (5% for ranged champions).
Presence of MindDamaging an enemy champion restores 6-50 (80% for ranged) mana or 6 energy.
Takedowns restore 15% of your maximum mana or energy.
Cooldown for damage restoration: 8s
Legend: HasteGain 1.5 basic ability haste for every Legend stack (
Earn progress toward Legend stacks for every champion takedown, epic monster takedown, large monster kill, and minion kill.
Last StandDeal 5% - 11% increased damage to champions while you are below 60% health. Max damage gained at 30% health.
Manaflow BandHitting an enemy champion with an ability permanently increases your maximum mana by 25, up to 250 mana.
After reaching 250 bonus mana, restore 1% of your missing mana every 5 seconds.
Cooldown: 15 seconds
CelerityAll movement bonuses are 7% more effective on you and gain
This alternative Cassiopeia rune build uses Conqueror as the keystone from the Precision tree. The primary runes are Conqueror, Presence of Mind, Legend: Haste, Last Stand. Cassiopeia's secondary rune tree is Sorcery with Manaflow Band, Transcendence. This setup achieves a 49.91% win rate (-0.0% win rate difference) with a 43.0% pick rate across 565 games.
Primary Tree
PrecisionConquerorBasic attacks or spells that deal damage to an enemy champion grant 2 stacks of Conqueror for 5s, gaining 1.8-4
When fully stacked, heal for 8% of the damage you deal to champions (5% for ranged champions).
Presence of MindDamaging an enemy champion restores 6-50 (80% for ranged) mana or 6 energy.
Takedowns restore 15% of your maximum mana or energy.
Cooldown for damage restoration: 8s
Legend: HasteGain 1.5 basic ability haste for every Legend stack (
Earn progress toward Legend stacks for every champion takedown, epic monster takedown, large monster kill, and minion kill.
Last StandDeal 5% - 11% increased damage to champions while you are below 60% health. Max damage gained at 30% health.
Manaflow BandHitting an enemy champion with an ability permanently increases your maximum mana by 25, up to 250 mana.
After reaching 250 bonus mana, restore 1% of your missing mana every 5 seconds.
Cooldown: 15 seconds
TranscendenceGain bonuses upon reaching the following levels:
Level 5: +5
Level 8: +5
Level 11: On Champion takedown, reduce the remaining cooldown of basic abilities by 20%.
Cassiopeia Runes - Frequently Asked Questions
What are the best Cassiopeia runes in patch 26.1?
The best Cassiopeia runes in patch 26.1 use the Precision tree with Conqueror, Presence of Mind, Legend: Haste, and Last Stand, and the Sorcery tree with Manaflow Band and Celerity. This rune setup achieves a 66.7% win rate with a 1.6% pick rate.
What is the win rate for Cassiopeia's best rune page?
Cassiopeia's best rune page has a 66.7% win rate in patch 26.1, which is +16.7% compared to Cassiopeia's average win rate. This rune setup has a 1.6% pick rate among Cassiopeia players.
What keystone should I use on Cassiopeia?
Conqueror from the Precision tree is the best keystone rune for Cassiopeia in patch 26.1. This keystone synergizes well with Cassiopeia's kit and provides a 66.7% win rate.
What is Cassiopeia's primary rune tree?
Cassiopeia's primary rune tree is Precision. The optimal Precision runes for Cassiopeia are Conqueror, Presence of Mind, Legend: Haste, and Last Stand, with Conqueror being the keystone of choice.
What is Cassiopeia's secondary rune tree?
Cassiopeia's best secondary rune tree is Sorcery. The recommended Sorcery runes are Manaflow Band and Celerity, which complement Cassiopeia's Precision primary tree.
What are alternative rune setups for Cassiopeia?
An alternative Cassiopeia rune setup uses Conqueror from the Precision tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.
How popular are Cassiopeia's runes?
Cassiopeia's top rune page has a 1.6% pick rate in patch 26.1. This indicates that 1.6% of Cassiopeia players use the Conqueror setup with Precision and Sorcery trees.