Cassiopeia, League of Legends champion
Win Rate
44.6%
Pick Rate
0.5%
Ban Rate
0.7%

CassiopeiaMid Runes: Keystone & Shards

Cassiopeia F TierMage
Patch26.19
Games473
LaneMid
TierAll Tiers
Last UpdatedOct 3, 2026 UTC
MethodologyData Methodology

Best Mid Cassiopeia runes for LoL Patch 26.19 - Deathfire Touch from the Sorcery tree with Precision secondary (45.3% WR, 33.6% pick rate). Cassiopeia's optimal primary runes are Deathfire Touch, Manaflow Band, Transcendence, Scorch. Secondary tree: Coup de Grace, Presence of Mind.

Cassiopeia performs best with Deathfire Touch as the keystone rune from the Sorcery tree. Cassiopeia's optimal primary runes are Deathfire Touch, Manaflow Band, Transcendence, Scorch. Cassiopeia's secondary rune tree is Precision with Coup de Grace, Presence of Mind. This rune setup achieves a 45.28% win rate (+0.7% win rate difference) with a 33.6% pick rate across 159 Cassiopeia games.
45.3%Win Rate
+0.7%WR Diff
33.6%Pick Rate
Deathfire TouchDeathfire Touch

Damaging a champion with an ability burns them for 3 - 12 based on level (+2.5% AP) (+7% bonus AD) magic damage per second. After burning for 3 seconds, the damage of the burn increases by 75% while they remain on fire.

Duration:
Single Target: 4s
Area of Effect: 2s
Damage over Time: 1s

Manaflow BandManaflow Band

Hitting an enemy champion with an ability permanently increases your maximum mana by 25, up to 250 mana.

After reaching 250 bonus mana, restore 1% of your missing mana every 5 seconds.

Cooldown: 15 seconds

TranscendenceTranscendence

Gain bonuses upon reaching the following levels:
Level 5: +5 Ability Haste
Level 8: +5 Ability Haste
Level 11: On Champion takedown, reduce the remaining cooldown of basic abilities by 20%.

ScorchScorch

Your next damaging ability hit sets champions on fire dealing 20 - 40 bonus magic damage based on level after 1s.

Cooldown: 10s

Coup de GraceCoup de Grace

Deal 8% more damage to champions who have less than 40% health.

Presence of MindPresence of Mind

Damaging an enemy champion restores 6-50 (80% for ranged) mana or 6 energy.

Takedowns restore 15% of your maximum mana or energy.

Cooldown for damage restoration: 8s

This alternative Cassiopeia rune build uses Stormraider's Surge as the keystone from the Sorcery tree. The primary runes are Stormraider's Surge, Manaflow Band, Transcendence, Scorch. Cassiopeia's secondary rune tree is Precision with Coup de Grace, Presence of Mind. This setup achieves a 48.98% win rate (+4.4% win rate difference) with a 10.4% pick rate across 49 games.
49.0%Win Rate
+4.4%WR Diff
10.4%Pick Rate
Stormraider's SurgeStormraider's Surge

Dealing 25% of a champion's maximum health within 3s grants 48% Move Speed and 50% Slow Resistance for 4s. Move Speed is 75% effective for ranged champions.
Cooldown: 20s - 10s

Manaflow BandManaflow Band

Hitting an enemy champion with an ability permanently increases your maximum mana by 25, up to 250 mana.

After reaching 250 bonus mana, restore 1% of your missing mana every 5 seconds.

Cooldown: 15 seconds

TranscendenceTranscendence

Gain bonuses upon reaching the following levels:
Level 5: +5 Ability Haste
Level 8: +5 Ability Haste
Level 11: On Champion takedown, reduce the remaining cooldown of basic abilities by 20%.

ScorchScorch

Your next damaging ability hit sets champions on fire dealing 20 - 40 bonus magic damage based on level after 1s.

Cooldown: 10s

Coup de GraceCoup de Grace

Deal 8% more damage to champions who have less than 40% health.

Presence of MindPresence of Mind

Damaging an enemy champion restores 6-50 (80% for ranged) mana or 6 energy.

Takedowns restore 15% of your maximum mana or energy.

Cooldown for damage restoration: 8s

These champions share at least 4 runes with Cassiopeia's recommended rune builds. use similar keystone and secondary runes, making them good alternatives if you enjoy Cassiopeia's playstyle or want to learn champions with familiar rune setups.Brand, Lux, Anivia, Taliyah, Ziggs and 5 others

Every Cassiopeia Mid Keystone and Secondary Tree (Patch 26.19)

961 games

Cassiopeia Mid runs Deathfire Touch in 58% of games, with a 47.9% win rate. Precision is the usual secondary tree (70%). Standard stat shards: Adaptive Force (offense), Adaptive Force (flex), Health Scaling (defense).

Keystones

RunePlayersWin RateGames
Deathfire TouchDeathfire TouchMost played58.5%47.9%562
ConquerorConqueror26.5%47.5%255
Stormraider's SurgeStormraider's Surge13.5%46.2%130

Secondary trees

RunePlayersWin RateGames
PrecisionPrecisionMost played69.5%47.5%668
SorcerySorcery25.4%47.1%244

Pick rate is the share of Cassiopeia games in this lane that used the rune; options under 40 games are left out. A higher win rate on a rarely picked rune is usually a matchup-specific choice, not a general upgrade.

Cassiopeia Minor Runes by Tree

Every minor rune Cassiopeia players take, grouped by rune tree, with how often it is picked and how often it wins.

Sorcery

RunePlayersWin RateGames
Manaflow BandManaflow BandMost played94.5%47.6%908
TranscendenceTranscendence82.6%46.2%794
ScorchScorch70.8%47.6%680
CelerityCelerity13.7%52.3%132

Precision

RunePlayersWin RateGames
Presence of MindPresence of MindMost played86.5%47.3%831
Coup de GraceCoup de Grace55.6%46.1%534
Legend: HasteLegend: Haste38.3%48.6%368
Last StandLast Stand23.6%46.3%227
Cut DownCut Down12.7%51.6%122

Cassiopeia Stat Shards

Which stat shards Cassiopeia players choose in each of the three shard rows, and the win rate of each.

RunePlayersWin RateGames
Adaptive Force (offense)Adaptive Force (offense)Most played92.8%47.1%892
Adaptive Force (flex)Adaptive Force (flex)89.2%46.9%857
Health Scaling (defense)Health Scaling (defense)82.3%47.8%791
Health (defense)Health (defense)14.3%46.7%137
Move Speed (flex)Move Speed (flex)10.2%52.0%98
Ability Haste (offense)Ability Haste (offense)5.3%62.7%51
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Cassiopeia Runes FAQ - Patch 26.19

What is the best keystone for Cassiopeia Mid?

Deathfire Touch: Cassiopeia Mid takes it in 58% of ranked games and wins 47.9% of 562 games. Alternatives: Conqueror (27%, 47.5%), Stormraider's Surge (14%, 46.2%).

What stat shards should Cassiopeia take?

Most Cassiopeia players take Adaptive Force (offense), Adaptive Force (flex), Health Scaling (defense) — one from each shard row.

What are the best Cassiopeia runes in patch 26.19?

The best Cassiopeia runes in patch 26.19 use the Sorcery tree with Deathfire Touch, Manaflow Band, Transcendence, and Scorch, and the Precision tree with Coup de Grace and Presence of Mind. This rune setup achieves a 45.3% win rate with a 33.6% pick rate.

What is the win rate for Cassiopeia's best rune page?

Cassiopeia's best rune page has a 45.3% win rate in patch 26.19, which is +0.7% compared to Cassiopeia's average win rate. This rune setup has a 33.6% pick rate among Cassiopeia players.

What keystone should I use on Cassiopeia?

Deathfire Touch from the Sorcery tree is the best keystone rune for Cassiopeia in patch 26.19. This keystone synergizes well with Cassiopeia's kit and provides a 45.3% win rate.

What is Cassiopeia's primary rune tree?

Cassiopeia's primary rune tree is Sorcery. The optimal Sorcery runes for Cassiopeia are Deathfire Touch, Manaflow Band, Transcendence, and Scorch, with Deathfire Touch being the keystone of choice.

What is Cassiopeia's secondary rune tree?

Cassiopeia's best secondary rune tree is Precision. The recommended Precision runes are Coup de Grace and Presence of Mind, which complement Cassiopeia's Sorcery primary tree.

What are alternative rune setups for Cassiopeia?

An alternative Cassiopeia rune setup uses Stormraider's Surge from the Sorcery tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.

How popular are Cassiopeia's runes?

Cassiopeia's top rune page has a 33.6% pick rate in patch 26.19. This indicates that 33.6% of Cassiopeia players use the Deathfire Touch setup with Sorcery and Precision trees.