Cassiopeia Runes
The top Cassiopeia runes in LoL patch 25.23 are Conqueror, Triumph, Legend: Haste, Coup de Grace for Cassiopeia's primary runes. Cassiopeia's runes in his secondary tree best utilizes Taste of Blood and Treasure Hunter. These Cassiopeia rune choices provide the best Cassiopeia rune build for ranked.
Serpentine Grace
Cassiopeia gains Move Speed per level, but she cannot purchase Boots items.
Noxious Blast
Cassiopeia blasts an area with Poison after a brief delay, granting her increased Move Speed if she hits an enemy champion.
Cost:- 50/
- 55/
- 60/
- 65/
- 70
Cooldown:- 4
Range:- 850
Miasma
Cassiopeia releases several clouds of poison, slowing, grounding, and lightly damaging enemies that pass through them. Grounded enemies cannot use Movement abilities.
Cost:- 70/
- 75/
- 80/
- 85/
- 90
Cooldown:- 24/
- 22/
- 20/
- 18/
- 16
Range:- 700
Twin Fang
Cassiopeia lets loose an attack that deals increased damage to Poisoned targets and heals her for a percentage of the damage dealt. If the target dies from this attack, Cassiopeia regains Mana.
Cost:- 40
Cooldown:- 1
Range:- 700
Petrifying Gaze
Cassiopeia releases a swirl of magical energy from her eyes, stunning any enemies in front of her that are facing her and slowing any others with their back turned.
Cost:- 100
Cooldown:- 120/
- 100/
- 80
Range:- 825
- Mage
Cassiopeia performs best with Conqueror as the keystone rune. The optimal primary runes for Cassiopeia include Conqueror, Triumph, Legend: Haste. This rune setup achieves a 1.00% win rate across 1 Cassiopeia games.
Primary Tree
Precision
This alternative Cassiopeia rune build uses Phase Rush as the keystone. This setup provides a different playstyle for Cassiopeia and achieves a 1.00% win rate. Consider this rune page when facing specific matchups or team compositions.
Primary Tree
Sorcery
Cassiopeia Runes - Frequently Asked Questions
What are the best Cassiopeia runes?
The best Cassiopeia runes in patch 25.23 are Conqueror, Triumph, Legend: Haste, and Coup de Grace for the primary tree, and Taste of Blood and Treasure Hunter for the secondary tree. These runes provide optimal performance for Cassiopeia.
What keystone should I use on Cassiopeia?
Conqueror is the best keystone rune for Cassiopeia. This keystone synergizes well with Cassiopeia's abilities and provides maximum value in most matchups.
What are Cassiopeia's secondary runes?
Cassiopeia's best secondary runes are Taste of Blood and Treasure Hunter. These secondary runes complement Cassiopeia's primary rune choices and enhance overall effectiveness.
Can I use different rune setups on Cassiopeia?
Yes, Cassiopeia can utilize different rune setups depending on matchup and playstyle. While Conqueror is most popular, alternative keystones may work better in specific situations.
