Dr. Mundo - League of Legends Champion
Win Rate
51.3%
Pick Rate
5.6%

Dr. Mundovs Lissandra

STankFighter
Patch26.4
Matches846,550
LaneAll Lanes
TierAll Tiers
Last UpdatedFeb 27, 2026
MethodologyData Methodology

Dr. Mundo vs Lissandra is a decisive matchup in LoL patch 26.4. Lissandra wins with a 60.0% win rate (+20.0%) over Dr. Mundo based on 5 games. Dr. Mundo wins the early laning phase while Lissandra scales better into the late game. Below you'll find the best Dr. Mundo build, runes, laning stats, and strategies for the Dr. Mundo vs Lissandra matchup.

Dr. Mundo Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Dr. Mundo performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Lissandra - 40.0% win rateLissandra(40.0%)
Dr. Mundo - 40.0% win rate in this matchup
Dr. Mundo
40.0% WR
VS
Lissandra vs Dr. Mundo matchup - 60.0% win rate
Lissandra
60.0% WR

Who Wins the Dr. Mundo vs Lissandra Matchup?

Lissandra wins the Dr. Mundo vs Lissandra matchup
Winner
Lissandra
Matches: 5
40.0%
Win Rate
60.0%
7.2
CS / min
8.0
836
DMG / min
1,072
8,774
Gold / game
8,894
515
Heal / min
173
1,110
DMG Mitigated / min
488
0.5
CC / min
1.6
50.0%
Early Game WR
50.0%
0.0%
Late Game WR
100.0%

Dr. Mundo vs Lissandra Matchup Summary

The Dr. Mundo vs Lissandra matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Lissandra wins with a 60.0% win rate compared to Dr. Mundo's 40.0%, giving Lissandra a 20.0 percentage point advantage. Game phase dynamics play a critical role here: Dr. Mundo controls the early laning stage, but Lissandra outscales as the game goes longer. The matchup shifts dramatically depending on game length — Dr. Mundo needs to press advantages before Lissandra reaches their power spikes, while Lissandra should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Lissandra leads by 1.1s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Lissandra has a strong advantage in this matchup. Dr. Mundo players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Lissandra overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Dr. Mundo vs Lissandra Laning Phase Breakdown

Lissandra wins the laning phase against Dr. Mundo in League of Legends

Lissandra is favored during the laning phase against Dr. Mundo, winning 4 out of 5 key stat categories. Lissandra holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
7.2Dr. Mundo
8.0Lissandra
Lissandra edges out Dr. Mundo by 0.8 CS per minute — a moderate farming advantage that adds up to roughly 11 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Lissandra.
Damage
836Dr. Mundo
1,072Lissandra
Lissandra heavily out-damages Dr. Mundo by 235 DMG/min, dominating both short trades and all-in fights. Dr. Mundo should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Lissandra's sustained damage advantage take over.
Economy
8,774Dr. Mundo
8,894Lissandra
Dr. Mundo and Lissandra generate nearly equal gold per game, with just a 120 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
0.5Dr. Mundo
1.6Lissandra
Lissandra brings significantly more crowd control than Dr. Mundo, with 1.1 more seconds of CC per minute. This large utility gap makes Lissandra far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Dr. Mundo should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
1,625Dr. Mundo
661Lissandra
Dr. Mundo vastly out-sustains Lissandra, healing and mitigating 964 more damage per minute. This massive durability gap means Dr. Mundo can absorb significant punishment and remain in lane while Lissandra is forced to recall. Building grievous wounds early is essential for Lissandra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Dr. Mundo Build Against Lissandra

Swiftmarch is the optimal boots choice against Lissandra, providing the mobility and stats Dr. Mundo needs most in this matchup. The top-performing core items for Dr. Mundo against Lissandra are Dead Man's Plate, Heartsteel and Warmog's Armor. This combination gives Dr. Mundo an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Dr. Mundo vs Lissandra matchup.

Early Game vs Late Game

Early Game
Dr. Mundo
50.0%
+0.0% advantage
Dr. Mundo early game win rateDr. Mundo50.0%
Lissandra early game win rateLissandra50.0%
Late Game
Lissandra
100.0%
+100.0% advantage
Dr. Mundo late game win rateDr. Mundo0.0%
Lissandra late game win rateLissandra100.0%

The early game (first 15 minutes) is a toss-up between Dr. Mundo and Lissandra, with Dr. Mundo holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Lissandra is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Dr. Mundo. Extended games heavily favor Lissandra, whose kit and scaling make them a dominant force in team fights and objective control.

The power dynamics shift as the game progresses — Dr. Mundo has the edge early, but Lissandra gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Dr. Mundo Runes Against Lissandra

Precision rune tree - Dr. Mundo primary runes vs LissandraPrecision
Fleet Footwork - best Dr. Mundo rune vs LissandraAbsorb Life - best Dr. Mundo rune vs LissandraLegend: Alacrity - best Dr. Mundo rune vs LissandraCoup de Grace - best Dr. Mundo rune vs Lissandra
Resolve rune tree - Dr. Mundo secondary runes vs LissandraResolve
Second Wind - best Dr. Mundo rune vs LissandraRevitalize - best Dr. Mundo rune vs Lissandra
100.0% WR

The Precision and Resolve rune setup gives Dr. Mundo the best tools to compete against Lissandra in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Dr. Mundo matchup data for League of Legends patch 26.4. The table below shows Dr. Mundo's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Dr. Mundo build, runes, laning stats, and early vs late game analysis for that specific matchup.

Dr. Mundo matchup win rates and stats in League of Legends patch 26.4
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
56.49%2634.587612,62954.6%57.8%
51.46%2421.167211,75750.4%52.4%
51.32%2295.893712,19952.5%50.4%
48.44%2266.087111,77949.4%47.8%
52.91%2256.21,06212,27761.0%46.9%
50.00%2194.392311,47052.3%47.7%
45.37%2176.889011,73048.9%43.0%
62.87%2026.088812,53962.0%63.7%
48.50%2014.879611,55148.9%48.2%
49.48%1927.01,00211,79454.4%45.0%
49.20%1873.082611,38446.5%52.3%
56.22%1874.674412,10254.4%57.5%
43.09%1816.61,02411,88237.8%48.4%
51.41%1791.973111,90646.5%56.0%
42.61%1781.778612,29341.3%43.8%
41.86%1721.374212,17539.0%44.2%
54.55%1541.572312,24655.6%53.7%
45.95%1492.176211,82337.1%53.9%
53.42%1471.167812,06452.9%53.9%
55.07%1386.81,15412,53854.0%55.7%
48.53%1361.072012,18350.8%46.6%
46.83%1265.81,09412,08662.5%37.2%
40.80%1256.679511,08131.5%47.9%
43.20%1251.480911,86744.3%42.2%
50.00%1235.589711,89145.8%54.0%
53.28%1221.373712,19755.0%51.6%
54.31%1171.172712,91648.8%57.5%
49.57%1156.599711,51237.0%58.0%
54.39%1146.883310,87850.0%59.6%
49.55%1111.475711,93143.9%55.6%
52.25%1114.484111,65846.3%57.9%
51.38%1096.086710,94949.1%53.9%
47.66%1074.376811,65458.2%36.5%
49.51%1046.985412,94444.7%52.3%
63.73%1037.11,03312,15960.4%66.7%
47.06%1026.678612,08247.8%46.4%
44.55%1017.191812,24656.8%35.1%
56.44%1011.376211,92863.3%50.0%
52.58%971.270112,25053.5%51.9%
54.64%977.192412,70452.6%55.9%
47.87%967.280412,14855.8%41.2%
47.37%956.288812,07245.6%49.0%
34.78%921.071711,78634.1%35.4%
53.49%891.375212,24451.2%55.8%
47.73%881.869511,36446.1%50.0%
64.37%871.173212,75562.8%65.9%
42.53%871.473512,41542.1%42.9%
50.00%861.177312,38050.0%50.0%
40.74%826.883510,78827.9%55.3%
54.88%821.176012,27948.6%59.6%
54.43%816.31,26812,80551.7%56.0%
47.50%812.280411,91455.6%40.9%
50.00%722.083612,02450.0%50.0%
56.34%712.772912,46460.9%54.2%
59.42%695.084512,08356.3%62.2%
57.35%680.966112,35554.3%60.6%
55.88%687.087212,36770.4%46.3%
52.24%672.485612,26748.4%55.6%
57.58%666.889111,64650.0%63.2%
53.97%635.281412,35465.5%44.1%
56.45%626.674911,93062.5%52.6%
58.06%621.888912,75457.1%58.5%
50.82%611.579813,39847.8%52.6%
51.72%582.181613,21350.0%52.8%
43.40%536.879711,79437.5%48.3%
54.00%512.380512,72657.1%51.7%
52.00%501.378112,39445.5%57.1%
50.00%506.397111,79748.0%52.0%
50.00%505.989211,30140.9%57.1%
47.92%482.265611,77752.6%44.8%
51.06%477.11,07512,09047.4%53.6%
44.68%476.195412,25552.6%39.3%
61.70%471.066911,84048.3%83.3%
59.09%456.075912,04668.4%52.0%
56.82%446.881413,18542.9%63.3%
64.29%426.892011,62666.7%62.5%
65.85%417.483312,89866.7%65.2%
60.00%400.974812,57352.9%65.2%
46.15%395.586712,61761.5%38.5%
58.33%371.377512,75566.7%50.0%
58.33%361.785712,15768.8%50.0%
55.56%361.867712,28156.3%55.0%
60.00%356.480711,51664.3%57.1%
54.29%356.883912,71450.0%56.0%
55.56%271.158512,18564.3%46.1%
65.38%262.073912,47675.0%61.1%
52.00%253.378511,37750.0%54.5%
54.17%241.373212,82062.5%50.0%
60.87%233.292913,43083.3%52.9%
80.00%202.980711,93390.9%66.7%
55.00%201.069912,59850.0%57.1%
60.00%207.692212,47057.1%61.5%
45.00%206.51,02212,92633.3%50.0%
36.84%196.573012,60420.0%42.9%
57.89%197.081212,29977.8%40.0%
26.67%154.464911,53033.3%22.2%
53.33%157.677911,98545.5%75.0%
50.00%142.163012,21160.0%44.4%
57.14%147.076211,33762.5%50.0%
35.71%142.174613,45325.0%40.0%
69.23%142.175311,06780.0%62.5%
71.43%147.31,00010,16970.0%75.0%
38.46%135.876611,21320.0%50.0%
41.67%127.377913,1700.0%62.5%
63.64%115.889911,03842.9%100.0%
50.00%103.167911,73525.0%66.7%
66.67%97.586012,87733.3%83.3%
66.67%93.678214,76766.7%66.7%
33.33%96.993610,97042.9%0.0%
66.67%96.292613,21250.0%80.0%
66.67%97.71,08013,86266.7%66.7%
87.50%87.31,01013,719100.0%80.0%
25.00%86.685010,90933.3%20.0%
28.57%77.385912,967100.0%0.0%
0.00%63.595612,1860.0%0.0%
66.67%64.386112,51533.3%100.0%
50.00%65.585714,686100.0%40.0%
0.00%67.46429,5900.0%0.0%
50.00%64.675412,12350.0%50.0%
50.00%65.960912,085100.0%40.0%
66.67%67.578213,00050.0%75.0%
33.33%63.21,14312,01950.0%25.0%
16.67%67.077213,7800.0%16.7%
60.00%55.359710,5130.0%75.0%
40.00%57.28368,77450.0%0.0%
40.00%57.857711,77366.7%0.0%
60.00%56.569911,6560.0%75.0%
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Dr. Mundo vs Lissandra - Frequently Asked Questions

How does Dr. Mundo do against Lissandra in League of Legends?

Lissandra wins the Dr. Mundo vs Lissandra matchup with a 60.0% win rate compared to Dr. Mundo's 40.0%, a 20.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.4.

How does Dr. Mundo do against Lissandra in the early game?

In the early game, Dr. Mundo has the advantage against Lissandra with a 50.0% win rate versus 50.0%. Dr. Mundo players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Dr. Mundo do against Lissandra in the late game?

In the late game, Lissandra takes over the Dr. Mundo vs Lissandra matchup with a 100.0% win rate compared to 0.0%. Lissandra scales better into team fights and objective contests after 25 minutes.

Who wins the Dr. Mundo vs Lissandra matchup?

Lissandra wins the matchup against Dr. Mundo with a 60.0% win rate in League of Legends patch 26.4. The 20.0 percentage point advantage means Lissandra is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Dr. Mundo build against Lissandra?

The best Dr. Mundo build against Lissandra includes Dead Man's Plate, Heartsteel, Warmog's Armor with Swiftmarch. Check the matchup breakdown above for the full item path and build order.

What are the best Dr. Mundo runes against Lissandra?

The best Dr. Mundo runes against Lissandra use the Precision primary tree with Resolve secondary. This rune setup achieves a 100.0% win rate in the Dr. Mundo vs Lissandra matchup. See the full rune breakdown in the matchup comparison above.

Does Dr. Mundo counter Lissandra?

No, Dr. Mundo struggles against Lissandra with only a 40.0% win rate. Lissandra has the advantage in this matchup. Dr. Mundo players should focus on safe farming and avoiding extended trades to minimize Lissandra's lead.

How do I play Dr. Mundo against Lissandra?

When playing Dr. Mundo against Lissandra, play cautiously and avoid Lissandra's power spikes. Look for jungle assistance and team-dependent plays since Lissandra has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.