
Dr. Mundo Runes
The top Dr. Mundo runes in LoL patch 25.23 are Phase Rush, Axiom Arcanist, Celerity, Scorch for Dr. Mundo's primary runes. Dr. Mundo's runes in his secondary tree best utilizes Second Wind and Overgrowth. These Dr. Mundo rune choices provide the best Dr. Mundo rune build for ranked.


Goes Where He Pleases
Dr. Mundo resists the first Immobilizing effect that hits him, instead losing Health and dropping a chemical cannister nearby. Dr. Mundo can pick it up by walking over it, restoring Health and reducing this Ability's Cooldown.
Dr. Mundo also has significantly increased Health regeneration.

Infected Bonesaw
Dr. Mundo throws an infected bonesaw, dealing damage to the first enemy hit based on their current health and slowing them.
Cost:- 0
Cooldown:- 4
Range:- 975


Heart Zapper
Dr. Mundo electrocutes himself, dealing persistent damage to nearby enemies and storing a portion of damage he takes. At the end of the duration or on Recast, Dr. Mundo deals a burst of damage to nearby enemies. If the burst hit an enemy, he heals a percentage of the stored damage.
Cost:- 0
Cooldown:- 17/
- 17/
- 16/
- 16/
- 15
Range:- 325


Blunt Force Trauma
Passive - Dr. Mundo gains bonus Attack Damage, increasing based on his max Health.
Active - Dr. Mundo slams his “medical” bag into an enemy, dealing additional damage based on his missing Health. If the enemy dies they are swatted away, dealing damage to enemies they pass through.Cost:- 0
Cooldown:- 9/
- 8/
- 8/
- 7/
- 6
Range:- 0


Maximum Dosage
Dr. Mundo pumps himself with chemicals, instantly healing a percent of his missing Health. He then gains Move Speed and regenerates a portion of his maximum Health over a long duration.
Cost:- 0
Cooldown:- 120
Range:- 20
- Tank,
- Fighter

Dr. Mundo performs best with Phase Rush as the keystone rune. The optimal primary runes for Dr. Mundo include Phase Rush, Axiom Arcanist, Celerity. This rune setup achieves a 1.00% win rate across 1 Dr. Mundo games.
Primary Tree
SorceryThis alternative Dr. Mundo rune build uses Arcane Comet as the keystone. This setup provides a different playstyle for Dr. Mundo and achieves a 1.00% win rate. Consider this rune page when facing specific matchups or team compositions.
Primary Tree
SorceryDr. Mundo Runes - Frequently Asked Questions
What are the best Dr. Mundo runes?
The best Dr. Mundo runes in patch 25.23 are Phase Rush, Axiom Arcanist, Celerity, and Scorch for the primary tree, and Second Wind and Overgrowth for the secondary tree. These runes provide optimal performance for Dr. Mundo.
What keystone should I use on Dr. Mundo?
Phase Rush is the best keystone rune for Dr. Mundo. This keystone synergizes well with Dr. Mundo's abilities and provides maximum value in most matchups.
What are Dr. Mundo's secondary runes?
Dr. Mundo's best secondary runes are Second Wind and Overgrowth. These secondary runes complement Dr. Mundo's primary rune choices and enhance overall effectiveness.
Can I use different rune setups on Dr. Mundo?
Yes, Dr. Mundo can utilize different rune setups depending on matchup and playstyle. While Phase Rush is most popular, alternative keystones may work better in specific situations.






































