Nocturne - League of Legends Champion
Win Rate
51.2%
Pick Rate
4.8%

Nocturnevs Vayne

AFighterAssassin
Patch26.10
Matches2,379,056
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 24, 2026
MethodologyData Methodology

Nocturne vs Vayne is a decisive matchup in LoL patch 26.10. Vayne wins with a 75.0% win rate (+50.0%) over Nocturne based on 8 games. Vayne holds the advantage in both the early and late game. Below you'll find the best Nocturne build, runes, laning stats, and strategies for the Nocturne vs Vayne matchup.

Nocturne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Nocturne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vayne - 25.0% win rateVayne(25.0%)
Nocturne - 25.0% win rate in this matchup
Nocturne
25.0% WR
VS
Vayne vs Nocturne matchup - 75.0% win rate
Vayne
75.0% WR

Who Wins the Nocturne vs Vayne Matchup?

Vayne wins the Nocturne vs Vayne matchup
Winner
Vayne
Matches: 8
25.0%
Win Rate
75.0%
2.1
CS / min
3.1
742
DMG / min
889
10,816
Gold / game
12,617
392
Heal / min
353
842
DMG Mitigated / min
537
6.3
CC / min
0.5
25.0%
Early Game WR
75.0%
25.0%
Late Game WR
75.0%

Nocturne vs Vayne Matchup Summary

The Nocturne vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 8 recent matches analyzed, Vayne wins with a 75.0% win rate compared to Nocturne's 25.0%, giving Vayne a 50.0 percentage point advantage. Vayne dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Nocturne players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Nocturne leads by 5.9s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne has a strong advantage in this matchup. Nocturne players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Vayne overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Nocturne vs Vayne Laning Phase Breakdown

Vayne wins the laning phase against Nocturne in League of Legends

Vayne is favored during the laning phase against Nocturne, winning 3 out of 5 key stat categories. Vayne holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
2.1Nocturne
3.1Vayne
Vayne significantly out-farms Nocturne by 1.0 CS per minute, accumulating an estimated 15 CS lead by mid game. This substantial farming gap gives Vayne a major gold advantage and earlier item completions. Nocturne players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
742Nocturne
889Vayne
Vayne heavily out-damages Nocturne by 147 DMG/min, dominating both short trades and all-in fights. Nocturne should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vayne's sustained damage advantage take over.
Economy
10,816Nocturne
12,617Vayne
Vayne generates a commanding 1,801 more gold per game than Nocturne. This substantial economic advantage means Vayne consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Nocturne should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
6.3Nocturne
0.5Vayne
Nocturne brings significantly more crowd control than Vayne, with 5.9 more seconds of CC per minute. This large utility gap makes Nocturne far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Vayne should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
1,234Nocturne
890Vayne
Nocturne vastly out-sustains Vayne, healing and mitigating 344 more damage per minute. This massive durability gap means Nocturne can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Best Nocturne Build Against Vayne

Plated Steelcaps is the optimal boots choice against Vayne, providing the mobility and stats Nocturne needs most in this matchup. The top-performing core items for Nocturne against Vayne are Stridebreaker, Death's Dance and Experimental Hexplate. This combination gives Nocturne an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Nocturne vs Vayne matchup.

Early Game vs Late Game

Early Game
Vayne
75.0%
+50.0% advantage
Nocturne early game win rateNocturne25.0%
Vayne early game win rateVayne75.0%
Late Game
Vayne
75.0%
+50.0% advantage
Nocturne late game win rateNocturne25.0%
Vayne late game win rateVayne75.0%

Vayne dominates the early game (first 15 minutes) with a commanding 75.0% win rate — a 50.0 percentage point lead over Nocturne. This lopsided early game means Vayne can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Vayne is far superior in the late game (25+ minutes), boasting a 75.0% win rate — 50.0 points above Nocturne. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.

Vayne holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Nocturne players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Nocturne Runes Against Vayne

Precision rune tree - Nocturne primary runes vs VaynePrecision
Lethal Tempo - best Nocturne rune vs VayneTriumph - best Nocturne rune vs VayneLegend: Alacrity - best Nocturne rune vs VayneCoup de Grace - best Nocturne rune vs Vayne
Inspiration rune tree - Nocturne secondary runes vs VayneInspiration
Magical Footwear - best Nocturne rune vs VayneCosmic Insight - best Nocturne rune vs Vayne
100.0% WR

The Precision and Inspiration rune setup gives Nocturne the best tools to compete against Vayne in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Nocturne matchup data for League of Legends patch 26.10. The table below shows Nocturne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Nocturne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Nocturne matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
55.68%5191.170012,76361.0%51.7%
49.61%5161.166712,39950.9%48.6%
45.09%4281.164712,07648.9%42.2%
49.04%4161.165112,13750.5%47.8%
48.87%3991.168113,06852.7%46.6%
46.08%3951.265412,50151.2%42.4%
51.52%2971.263912,84650.0%52.6%
52.92%2911.265812,70165.2%45.3%
48.28%2901.263812,05854.5%43.0%
53.50%2861.166312,74754.5%52.8%
46.21%2641.271112,03843.4%48.9%
55.14%2141.167312,76651.2%57.7%
52.36%1911.169012,55951.2%53.2%
49.18%1831.062812,22848.7%49.5%
48.63%1831.165412,85655.1%44.7%
51.38%1811.268812,74050.0%52.5%
49.71%1751.164212,25645.2%52.9%
55.81%1721.268812,68366.7%50.0%
58.93%1681.271612,61660.2%57.6%
53.37%1631.168713,40059.3%50.0%
60.39%1541.271913,37965.6%57.0%
53.59%1531.263912,35455.7%52.2%
54.48%1451.062711,88758.2%51.3%
52.48%1411.369712,62052.6%52.4%
51.08%1391.166612,11558.3%45.6%
47.76%1341.168412,78647.3%48.1%
49.21%1261.168112,83457.4%43.1%
50.82%1221.167412,05750.9%50.8%
50.85%1181.268612,88156.0%47.1%
55.65%1151.063811,88950.0%60.3%
49.56%1131.368013,70351.3%48.6%
57.66%1111.267713,44847.1%62.3%
59.09%1101.168413,00161.4%57.6%
50.60%831.570312,92154.3%47.9%
51.85%811.165312,05845.5%59.5%
49.37%791.273612,78756.3%44.7%
51.28%781.169512,90562.5%43.5%
50.65%771.165912,07154.0%47.5%
53.85%651.165811,99751.4%56.7%
51.56%641.164812,44344.0%56.4%
60.94%641.163912,55345.8%70.0%
48.44%641.161812,49240.9%52.4%
56.25%641.366913,29073.1%44.7%
48.39%621.378612,28851.9%45.7%
59.26%541.074712,53255.6%63.0%
58.82%511.468913,55060.0%58.1%
52.94%511.261012,57455.0%51.6%
43.75%481.170812,44943.5%44.0%
46.67%451.174814,07057.1%41.9%
31.82%441.663712,11428.6%33.3%
50.00%401.167712,08147.1%52.2%
55.00%401.170712,98865.0%45.0%
45.00%401.663913,02669.2%33.3%
43.59%391.361912,53525.0%56.5%
35.90%391.469213,58242.9%32.0%
36.11%361.071312,07927.8%44.4%
47.06%341.265112,47666.7%31.6%
35.48%311.462612,19146.7%25.0%
60.00%301.271813,02250.0%66.7%
59.26%271.263311,87766.7%53.3%
55.56%271.357210,68461.5%50.0%
34.62%261.480013,42444.4%29.4%
62.50%241.778415,05171.4%58.8%
62.50%241.476413,82463.6%61.5%
34.78%231.060711,80216.7%54.5%
50.00%221.670412,63880.0%25.0%
55.56%182.672512,97557.1%54.5%
50.00%181.468614,44560.0%46.1%
56.25%160.880313,67433.3%61.5%
50.00%163.165512,05650.0%50.0%
41.67%121.461112,58980.0%14.3%
63.64%112.378912,686100.0%33.3%
40.00%101.376613,16850.0%33.3%
44.44%91.562810,54540.0%50.0%
25.00%82.174210,81625.0%25.0%
37.50%81.870113,0170.0%60.0%
87.50%82.269511,981100.0%83.3%
28.57%73.569813,2960.0%50.0%
71.43%74.767911,70466.7%75.0%
33.33%61.363812,65333.3%33.3%
50.00%61.063912,90875.0%0.0%
50.00%62.597016,670100.0%25.0%
83.33%66.881613,47050.0%100.0%
40.00%52.780116,363100.0%25.0%
20.00%53.591213,73133.3%0.0%
40.00%52.074713,47633.3%50.0%
40.00%56.31,15214,94850.0%33.3%

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Nocturne vs Vayne - Frequently Asked Questions

How does Nocturne do against Vayne in League of Legends?

Vayne wins the Nocturne vs Vayne matchup with a 75.0% win rate compared to Nocturne's 25.0%, a 50.0 percentage point difference. This data is based on 8 recent ranked games in patch 26.10.

How does Nocturne do against Vayne in the early game?

In the early game, Vayne has the advantage against Nocturne with a 75.0% win rate versus 25.0%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Nocturne do against Vayne in the late game?

In the late game, Vayne takes over the Nocturne vs Vayne matchup with a 75.0% win rate compared to 25.0%. Vayne scales better into team fights and objective contests after 25 minutes.

Who wins the Nocturne vs Vayne matchup?

Vayne wins the matchup against Nocturne with a 75.0% win rate in League of Legends patch 26.10. The 50.0 percentage point advantage means Vayne is significantly favored in this lane matchup based on 8 games analyzed.

What is the best Nocturne build against Vayne?

The best Nocturne build against Vayne includes Stridebreaker, Death's Dance, Experimental Hexplate with Plated Steelcaps. Check the matchup breakdown above for the full item path and build order.

What are the best Nocturne runes against Vayne?

The best Nocturne runes against Vayne use the Precision primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Nocturne vs Vayne matchup. See the full rune breakdown in the matchup comparison above.

Does Nocturne counter Vayne?

No, Nocturne struggles against Vayne with only a 25.0% win rate. Vayne has the advantage in this matchup. Nocturne players should focus on safe farming and avoiding extended trades to minimize Vayne's lead.

How do I play Nocturne against Vayne?

When playing Nocturne against Vayne, play cautiously and avoid Vayne's power spikes. Look for jungle assistance and team-dependent plays since Vayne has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.