Nocturne - League of Legends Champion
Win Rate
51.2%
Pick Rate
4.2%

Nocturnevs Karthus

AFighterAssassin
Patch26.14
Matches491,560
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 25, 2026
MethodologyData Methodology

Nocturne vs Karthus is a decisive matchup in LoL patch 26.14. Nocturne wins with a 57.1% win rate (+14.3%) over Karthus based on 21 games. Karthus wins the early laning phase while Nocturne scales better into the late game. Below you'll find the best Nocturne build, runes, laning stats, and strategies for the Nocturne vs Karthus matchup.

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Counter picks in champ select

Nocturne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Nocturne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Nocturne - 57.1% win rate in this matchup
Nocturne
57.1% WR
VS
Karthus vs Nocturne matchup - 42.9% win rate
Karthus
42.9% WR

Who Wins the Nocturne vs Karthus Matchup?

Nocturne wins the Nocturne vs Karthus matchup
Winner
Nocturne
Matches: 21
57.1%
Win Rate
42.9%
1.3
CS / min
1.6
765
DMG / min
1,273
14,411
Gold / game
14,869
527
Heal / min
317
898
DMG Mitigated / min
515
6.3
CC / min
0.6
37.5%
Early Game WR
62.5%
69.2%
Late Game WR
30.8%

Nocturne vs Karthus Matchup Summary

The Nocturne vs Karthus matchup is a decisive matchup in League of Legends ranked play. Based on 21 recent matches analyzed, Nocturne wins with a 57.1% win rate compared to Karthus's 42.9%, giving Nocturne a 14.3 percentage point advantage. Game phase dynamics play a critical role here: Karthus controls the early laning stage, but Nocturne outscales as the game goes longer. The matchup shifts dramatically depending on game length — Karthus needs to press advantages before Nocturne reaches their power spikes, while Nocturne should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Nocturne leads by 5.7s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Nocturne players can confidently pick into Karthus and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Karthus away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Nocturne vs Karthus Laning Phase Breakdown

Karthus wins the laning phase against Nocturne in League of Legends

Karthus is favored during the laning phase against Nocturne, winning 3 out of 5 key stat categories. Karthus holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
1.3Nocturne
1.6Karthus
Karthus edges out Nocturne by 0.3 CS per minute — a moderate farming advantage that adds up to roughly 5 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Karthus.
Damage
765Nocturne
1,273Karthus
Karthus heavily out-damages Nocturne by 508 DMG/min, dominating both short trades and all-in fights. Nocturne should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Karthus's sustained damage advantage take over.
Economy
14,411Nocturne
14,869Karthus
Karthus earns 458 more gold per game than Nocturne, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Karthus slightly faster item completions.
Utility
6.3Nocturne
0.6Karthus
Nocturne brings significantly more crowd control than Karthus, with 5.7 more seconds of CC per minute. This large utility gap makes Nocturne far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Karthus should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
1,425Nocturne
831Karthus
Nocturne vastly out-sustains Karthus, healing and mitigating 593 more damage per minute. This massive durability gap means Nocturne can absorb significant punishment and remain in lane while Karthus is forced to recall. Building grievous wounds early is essential for Karthus, and focusing on burst trade patterns rather than sustained fights is critical.

Best Nocturne Build Against Karthus

Mercury's Treads is the optimal boots choice against Karthus, providing the mobility and stats Nocturne needs most in this matchup. The top-performing core items for Nocturne against Karthus are Axiom Arc, Stridebreaker and Death's Dance. This combination gives Nocturne an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 2 games — well above average and making it the top item path against Karthus. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Nocturne vs Karthus matchup.

Early Game vs Late Game

Early Game
Karthus
62.5%
+25.0% advantage
Nocturne early game win rateNocturne37.5%
Karthus early game win rateKarthus62.5%
Late Game
Nocturne
69.2%
+38.5% advantage
Nocturne late game win rateNocturne69.2%
Karthus late game win rateKarthus30.8%

Karthus dominates the early game (first 15 minutes) with a commanding 62.5% win rate — a 25.0 percentage point lead over Nocturne. This lopsided early game means Karthus can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Nocturne is far superior in the late game (25+ minutes), boasting a 69.2% win rate — 38.5 points above Karthus. Extended games heavily favor Nocturne, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Karthus must aggressively press their early advantage and close out the game before Nocturne reaches their scaling breakpoints. If Nocturne survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Nocturne Runes Against Karthus

Domination rune tree - Nocturne primary runes vs KarthusDomination
Hail of Blades - best Nocturne rune vs KarthusSudden Impact - best Nocturne rune vs KarthusGrisly Mementos - best Nocturne rune vs KarthusUltimate Hunter - best Nocturne rune vs Karthus
Precision rune tree - Nocturne secondary runes vs KarthusPrecision
Legend: Alacrity - best Nocturne rune vs KarthusTriumph - best Nocturne rune vs Karthus
60.0% WR

Running Domination primary with Precision secondary allows Nocturne to press their advantage against Karthus, amplifying the strengths that make this a favorable matchup.


Nocturne matchup data for League of Legends patch 26.14. The table below shows Nocturne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Nocturne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Nocturne matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
53.04%2301.170712,42254.3%52.2%
46.83%2051.269212,48951.3%44.2%
52.88%1911.167711,72151.1%54.4%
51.93%1811.167611,95055.7%49.0%
48.81%1681.171812,20342.6%53.0%
48.18%1371.367613,06446.9%48.9%
48.18%1371.168912,91652.0%46.0%
45.45%1321.270912,10546.1%45.0%
50.00%1321.172512,72150.0%50.0%
57.14%1121.271312,29359.2%55.6%
52.83%1061.173113,40654.3%52.1%
59.05%1051.177012,10053.1%64.3%
38.83%1031.169112,53647.6%32.8%
50.98%1021.176412,52652.8%50.0%
48.39%931.062411,89258.1%43.5%
54.95%911.272512,50253.9%55.8%
50.59%851.167412,19732.4%62.8%
50.00%841.269411,60051.2%48.8%
55.95%841.271912,25657.1%55.1%
58.54%821.069111,42159.5%57.5%
57.14%770.969012,15361.3%54.4%
48.68%761.271412,42250.0%47.7%
42.03%691.165611,67330.6%54.5%
58.73%631.175213,44060.0%58.1%
66.07%561.172912,04073.1%60.0%
47.27%551.274713,08666.7%37.8%
49.02%511.269512,45452.6%46.9%
48.00%501.172511,56347.6%48.3%
54.00%501.268112,47356.3%52.9%
44.90%491.169312,84541.2%46.9%
59.18%491.174113,23455.6%61.3%
51.06%471.163112,25950.0%52.0%
48.84%431.382713,85458.3%45.2%
40.48%421.268512,22444.4%37.5%
48.72%391.373412,51330.8%57.7%
59.46%371.166312,27966.7%54.5%
45.71%351.065911,34943.8%47.4%
39.39%331.666710,90250.0%29.4%
62.50%321.169612,69675.0%55.0%
50.00%301.262310,95257.1%43.8%
55.56%271.480613,11981.8%37.5%
48.00%251.168613,68266.7%37.5%
52.00%250.963411,58725.0%64.7%
37.50%241.564111,95450.0%31.3%
56.52%231.263813,30550.0%60.0%
40.91%221.160411,66846.1%33.3%
45.45%221.466810,81763.6%27.3%
57.14%211.376514,41137.5%69.2%
73.68%191.058410,93755.6%90.0%
44.44%181.176013,13450.0%40.0%
37.50%161.560911,69342.9%33.3%
66.67%151.265412,47071.4%62.5%
60.00%150.869013,02580.0%50.0%
57.14%141.271012,28066.7%50.0%
35.71%141.162312,27742.9%28.6%
42.86%141.375912,05520.0%55.6%
61.54%131.259112,56275.0%55.6%
61.54%131.075311,54650.0%66.7%
46.15%131.172511,11028.6%66.7%
54.55%111.273410,81283.3%20.0%
63.64%110.962011,14962.5%66.7%
54.55%113.358810,04360.0%50.0%
40.00%101.14919,10457.1%0.0%
60.00%100.883411,84960.0%60.0%
55.56%91.87219,72133.3%66.7%
44.44%91.381615,08550.0%40.0%
62.50%81.57408,43050.0%75.0%
25.00%81.153010,8230.0%40.0%
57.14%71.787417,5000.0%57.1%
71.43%71.377314,970100.0%66.7%
50.00%60.765111,34433.3%66.7%
66.67%61.680210,05875.0%50.0%
0.00%61.270012,1480.0%0.0%
50.00%61.353912,891100.0%0.0%
50.00%61.266910,99533.3%66.7%
66.67%61.890914,450100.0%33.3%
40.00%52.786412,19733.3%50.0%
40.00%55.26819,01466.7%0.0%
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Nocturne vs Karthus - Frequently Asked Questions

How does Nocturne do against Karthus in League of Legends?

Nocturne wins the Nocturne vs Karthus matchup with a 57.1% win rate compared to Karthus's 42.9%, a 14.3 percentage point difference. This data is based on 21 recent ranked games in patch 26.14.

How does Nocturne do against Karthus in the early game?

In the early game, Karthus has the advantage against Nocturne with a 62.5% win rate versus 37.5%. Karthus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Nocturne do against Karthus in the late game?

In the late game, Nocturne takes over the Nocturne vs Karthus matchup with a 69.2% win rate compared to 30.8%. Nocturne scales better into team fights and objective contests after 25 minutes.

Who wins the Nocturne vs Karthus matchup?

Nocturne wins the matchup against Karthus with a 57.1% win rate in League of Legends patch 26.14. The 14.3 percentage point advantage means Nocturne is significantly favored in this lane matchup based on 21 games analyzed.

What is the best Nocturne build against Karthus?

The best Nocturne build against Karthus includes Axiom Arc, Stridebreaker, Death's Dance with Mercury's Treads. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Nocturne runes against Karthus?

The best Nocturne runes against Karthus use the Domination primary tree with Precision secondary. This rune setup achieves a 60.0% win rate in the Nocturne vs Karthus matchup. See the full rune breakdown in the matchup comparison above.

Does Nocturne counter Karthus?

Yes, Nocturne has a favorable matchup against Karthus with a 57.1% win rate. Nocturne strongly counters Karthus in lane based on current patch 26.14 data.

How do I play Nocturne against Karthus?

When playing Nocturne against Karthus, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Karthus. Build the recommended items and runes for this specific matchup for the best results.