Nocturne - League of Legends Champion
Win Rate
52.2%
Pick Rate
4.5%

Nocturnevs Karthus

SFighterAssassin
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 25, 2026
MethodologyData Methodology

Nocturne vs Karthus is a decisive matchup in LoL patch 26.7. Karthus wins with a 58.3% win rate (+16.7%) over Nocturne based on 36 games. Nocturne wins the early laning phase while Karthus scales better into the late game. Below you'll find the best Nocturne build, runes, laning stats, and strategies for the Nocturne vs Karthus matchup.

Nocturne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Nocturne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Karthus - 41.7% win rateKarthus(41.7%)
Nocturne - 41.7% win rate in this matchup
Nocturne
41.7% WR
VS
Karthus vs Nocturne matchup - 58.3% win rate
Karthus
58.3% WR

Who Wins the Nocturne vs Karthus Matchup?

Karthus wins the Nocturne vs Karthus matchup
Winner
Karthus
Matches: 36
41.7%
Win Rate
58.3%
1.1
CS / min
1.4
697
DMG / min
1,185
13,288
Gold / game
14,863
528
Heal / min
330
805
DMG Mitigated / min
540
5.9
CC / min
0.6
53.9%
Early Game WR
46.1%
34.8%
Late Game WR
65.2%

Nocturne vs Karthus Matchup Summary

The Nocturne vs Karthus matchup is a decisive matchup in League of Legends ranked play. Based on 36 recent matches analyzed, Karthus wins with a 58.3% win rate compared to Nocturne's 41.7%, giving Karthus a 16.7 percentage point advantage. Game phase dynamics play a critical role here: Nocturne controls the early laning stage, but Karthus outscales as the game goes longer. The matchup shifts dramatically depending on game length — Nocturne needs to press advantages before Karthus reaches their power spikes, while Karthus should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Nocturne leads by 5.3s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Karthus has a strong advantage in this matchup. Nocturne players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Karthus overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Nocturne vs Karthus Laning Phase Breakdown

Karthus wins the laning phase against Nocturne in League of Legends

Karthus is favored during the laning phase against Nocturne, winning 3 out of 5 key stat categories. Karthus holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
1.1Nocturne
1.4Karthus
Nocturne and Karthus farm at nearly identical rates in this matchup, with only a 0.3 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
697Nocturne
1,185Karthus
Karthus heavily out-damages Nocturne by 488 DMG/min, dominating both short trades and all-in fights. Nocturne should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Karthus's sustained damage advantage take over.
Economy
13,288Nocturne
14,863Karthus
Karthus generates a commanding 1,574 more gold per game than Nocturne. This substantial economic advantage means Karthus consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Nocturne should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
5.9Nocturne
0.6Karthus
Nocturne brings significantly more crowd control than Karthus, with 5.3 more seconds of CC per minute. This large utility gap makes Nocturne far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Karthus should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
1,334Nocturne
871Karthus
Nocturne vastly out-sustains Karthus, healing and mitigating 463 more damage per minute. This massive durability gap means Nocturne can absorb significant punishment and remain in lane while Karthus is forced to recall. Building grievous wounds early is essential for Karthus, and focusing on burst trade patterns rather than sustained fights is critical.

Best Nocturne Build Against Karthus

Mercury's Treads is the optimal boots choice against Karthus, providing the mobility and stats Nocturne needs most in this matchup. The top-performing core items for Nocturne against Karthus are Stridebreaker, Experimental Hexplate and Black Cleaver. This combination gives Nocturne an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 66.7% win rate across 3 games — well above average and making it the top item path against Karthus. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Nocturne vs Karthus matchup.

Early Game vs Late Game

Early Game
Nocturne
53.9%
+7.7% advantage
Nocturne early game win rateNocturne53.9%
Karthus early game win rateKarthus46.1%
Late Game
Karthus
65.2%
+30.4% advantage
Nocturne late game win rateNocturne34.8%
Karthus late game win rateKarthus65.2%

Nocturne dominates the early game (first 15 minutes) with a commanding 53.9% win rate — a 7.7 percentage point lead over Karthus. This lopsided early game means Nocturne can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Karthus is far superior in the late game (25+ minutes), boasting a 65.2% win rate — 30.4 points above Nocturne. Extended games heavily favor Karthus, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Nocturne must aggressively press their early advantage and close out the game before Karthus reaches their scaling breakpoints. If Karthus survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Nocturne Runes Against Karthus

Precision rune tree - Nocturne primary runes vs KarthusPrecision
Conqueror - best Nocturne rune vs KarthusTriumph - best Nocturne rune vs KarthusLegend: Alacrity - best Nocturne rune vs KarthusLast Stand - best Nocturne rune vs Karthus
Domination rune tree - Nocturne secondary runes vs KarthusDomination
Grisly Mementos - best Nocturne rune vs KarthusUltimate Hunter - best Nocturne rune vs Karthus
45.5% WR

The Precision and Domination rune setup gives Nocturne the best tools to compete against Karthus in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Nocturne matchup data for League of Legends patch 26.7. The table below shows Nocturne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Nocturne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Nocturne matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
56.31%2221.266512,50658.2%54.5%
51.46%2061.165312,66756.3%47.3%
44.88%2051.163112,56646.8%43.2%
48.97%1941.163812,89443.5%53.2%
53.37%1631.166912,37457.9%49.4%
44.30%1491.167312,90042.3%46.1%
57.69%1301.168413,11267.2%49.3%
54.62%1301.170112,85857.1%52.2%
52.94%1191.172912,88754.1%51.7%
60.50%1191.372314,33663.2%59.3%
54.87%1131.265012,35156.9%53.2%
46.90%1131.377212,20642.0%50.8%
49.54%1091.271613,41461.9%41.8%
52.58%971.168413,54260.5%47.5%
49.48%971.170112,15652.9%45.6%
58.14%861.167912,56861.1%56.0%
47.62%841.164112,57748.6%46.8%
58.02%811.168812,13557.5%58.5%
47.44%781.268913,35834.4%56.5%
44.16%771.171312,50039.5%48.7%
49.33%751.166613,08066.7%39.6%
56.94%721.263212,40951.4%62.9%
51.43%701.467412,86555.9%47.2%
55.07%691.167313,13353.1%56.8%
42.65%681.272713,15237.5%47.2%
52.24%671.165212,17747.4%58.6%
45.31%641.268312,72651.5%38.7%
57.38%611.169212,15948.1%64.7%
49.18%611.170212,27146.7%51.6%
48.33%601.172912,67850.0%47.1%
51.67%601.366211,73657.1%44.0%
55.93%591.067711,62455.6%56.5%
36.84%571.168312,90636.4%37.1%
50.88%571.371313,49259.3%43.3%
41.07%561.064212,50933.3%48.3%
59.62%521.272413,29854.2%64.3%
43.48%461.269812,50550.0%36.4%
37.50%401.476312,91037.5%37.5%
56.41%391.465812,43965.0%47.4%
41.67%361.072012,25831.3%50.0%
41.67%361.169713,28853.9%34.8%
44.12%341.262012,92450.0%40.9%
55.88%341.167613,00550.0%61.1%
30.30%331.365412,72623.1%35.0%
46.88%321.669111,68244.4%50.0%
54.84%310.957910,92350.0%58.8%
56.67%301.160912,35350.0%62.5%
41.38%291.375213,75850.0%38.1%
29.63%271.049911,88736.4%25.0%
46.15%261.458011,38530.0%56.3%
47.83%231.868812,14345.5%50.0%
52.17%231.676513,70271.4%43.8%
63.64%221.672013,71362.5%64.3%
59.09%221.266112,72157.1%60.0%
57.14%211.977913,68257.1%57.1%
55.00%201.566212,46877.8%36.4%
52.63%191.572714,16071.4%41.7%
40.00%151.465213,6350.0%54.5%
50.00%140.958212,16366.7%20.0%
63.64%113.788615,561100.0%55.6%
54.55%111.288115,054100.0%37.5%
36.36%111.282015,36366.7%25.0%
45.45%112.877512,06133.3%50.0%
40.00%102.667012,90950.0%33.3%
60.00%100.984914,019100.0%33.3%
70.00%101.082414,71680.0%60.0%
70.00%101.165812,05075.0%66.7%
50.00%82.385012,75575.0%25.0%
62.50%84.874312,878100.0%50.0%
42.86%71.780712,91075.0%0.0%
42.86%71.159712,0740.0%75.0%
57.14%75.685114,31466.7%50.0%
57.14%71.671513,09866.7%50.0%
57.14%75.283112,01225.0%100.0%
33.33%61.171312,57766.7%0.0%
100.00%61.966013,983100.0%100.0%

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Nocturne vs Karthus - Frequently Asked Questions

How does Nocturne do against Karthus in League of Legends?

Karthus wins the Nocturne vs Karthus matchup with a 58.3% win rate compared to Nocturne's 41.7%, a 16.7 percentage point difference. This data is based on 36 recent ranked games in patch 26.7.

How does Nocturne do against Karthus in the early game?

In the early game, Nocturne has the advantage against Karthus with a 53.9% win rate versus 46.1%. Nocturne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Nocturne do against Karthus in the late game?

In the late game, Karthus takes over the Nocturne vs Karthus matchup with a 65.2% win rate compared to 34.8%. Karthus scales better into team fights and objective contests after 25 minutes.

Who wins the Nocturne vs Karthus matchup?

Karthus wins the matchup against Nocturne with a 58.3% win rate in League of Legends patch 26.7. The 16.7 percentage point advantage means Karthus is significantly favored in this lane matchup based on 36 games analyzed.

What is the best Nocturne build against Karthus?

The best Nocturne build against Karthus includes Stridebreaker, Experimental Hexplate, Black Cleaver with Mercury's Treads. This build achieves a 66.7% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Nocturne runes against Karthus?

The best Nocturne runes against Karthus use the Precision primary tree with Domination secondary. This rune setup achieves a 45.5% win rate in the Nocturne vs Karthus matchup. See the full rune breakdown in the matchup comparison above.

Does Nocturne counter Karthus?

No, Nocturne struggles against Karthus with only a 41.7% win rate. Karthus has the advantage in this matchup. Nocturne players should focus on safe farming and avoiding extended trades to minimize Karthus's lead.

How do I play Nocturne against Karthus?

When playing Nocturne against Karthus, play cautiously and avoid Karthus's power spikes. Look for jungle assistance and team-dependent plays since Karthus has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.