Sejuani - League of Legends Champion
Win Rate
51.0%
Pick Rate
1.4%

SejuaniRunes

ATank
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 20, 2026
MethodologyData Methodology

Best Sejuani runes for LoL Patch 26.7 - Aftershock from the Resolve tree with Domination secondary (83.3% WR, 0.9% pick rate). Sejuani's optimal primary runes are Aftershock, Font of Life, Conditioning, Overgrowth. Secondary tree: Cheap Shot, Ultimate Hunter.

Sejuani performs best with Aftershock as the keystone rune from the Resolve tree. Sejuani's optimal primary runes are Aftershock, Font of Life, Conditioning, Overgrowth. Sejuani's secondary rune tree is Domination with Cheap Shot, Ultimate Hunter. This rune setup achieves a 83.33% win rate (+32.4% win rate difference) with a 0.9% pick rate across 24 Sejuani games.
83.3%Win Rate
+32.4%WR Diff
0.9%Pick Rate
AftershockAftershock

After immobilizing an enemy champion, increase your Armor and Magic Resist by 35 + 80% of your Bonus Resists for 2.5s. Then explode, dealing magic damage to nearby enemies.

Damage: 25 - 120 (+8% of your bonus health)
Cooldown: 20s

Resistance bonus from Aftershock capped at: 80-150 (based on level)

Font of LifeFont of Life

Impairing the movement of an enemy champion restores @BaseHeal@ Health to you and the lowest health nearby allied champion.

70% effect for Ranged Users.

Cooldown: 20s

ConditioningConditioning

After 12 min gain +8 Armor and +8 Magic Resist and increase your Armor and Magic Resist by 3%.

OvergrowthOvergrowth

Absorb life essence from monsters or enemy minions that die near you, permanently gaining 3 maximum health for every 8.

When you've absorbed 120 monsters or enemy minions, gain an additional 3.5% maximum health.

Cheap ShotCheap Shot

Damaging champions with impaired movement or actions deals 10 - 45 bonus true damage (based on level).

Cooldown: 4s
Activates on damage occurring after the impairment.

Ultimate HunterUltimate Hunter

Your ultimate gains 6 Ability Haste, plus an additional 5 Ability Haste per Bounty Hunter stack. Bounty Hunter stacks are earned the first time you get a takedown on each enemy champion.

This alternative Sejuani rune build uses Grasp of the Undying as the keystone from the Resolve tree. The primary runes are Grasp of the Undying, Demolish, Second Wind, Overgrowth. Sejuani's secondary rune tree is Inspiration with Biscuit Delivery, Cosmic Insight. This setup achieves a 74.07% win rate (+23.1% win rate difference) with a 1.0% pick rate across 27 games.
74.1%Win Rate
+23.1%WR Diff
1.0%Pick Rate
Grasp of the UndyingGrasp of the Undying

Every 4s in combat, your next basic attack on a champion will:

  • Deal bonus magic damage equal to 3.5% of your max health
  • Heal you for 1.3% of your max health
  • Permanently increase your health by 5
    Ranged Champions: Damage, healing, and permanent health gained are 40% effective.

  • DemolishDemolish

    Your third attack against towers deals [85 (+28% max Health) Melee || 50 (+20% max Health) Ranged] bonus physical damage.

    Cooldown: 30s

    Second WindSecond Wind

    After taking damage from an enemy champion, heal for 4% of your missing health over 10s.

    OvergrowthOvergrowth

    Absorb life essence from monsters or enemy minions that die near you, permanently gaining 3 maximum health for every 8.

    When you've absorbed 120 monsters or enemy minions, gain an additional 3.5% maximum health.

    Biscuit DeliveryBiscuit Delivery

    Biscuit Delivery: Gain a Total Biscuit of Everlasting Will every 2 mins, until 6 min.

    Biscuits restore 20 + 2% of your maximum health, increased by up to 100% based on missing Health. Consuming or selling a Biscuit permanently increases your max health by 30.

    Cosmic InsightCosmic Insight

    +18 Summoner Spell Haste
    +10 Item Haste

    These champions share at least 4 runes with Sejuani's recommended rune builds. use similar keystone and secondary runes, making them good alternatives if you enjoy Sejuani's playstyle or want to learn champions with familiar rune setups.K'Sante, Shen, Leona, Dr. Mundo, Illaoi

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    Sejuani Runes - Frequently Asked Questions

    What are the best Sejuani runes in patch 26.7?

    The best Sejuani runes in patch 26.7 use the Resolve tree with Aftershock, Font of Life, Conditioning, and Overgrowth, and the Domination tree with Cheap Shot and Ultimate Hunter. This rune setup achieves a 83.3% win rate with a 0.9% pick rate.

    What is the win rate for Sejuani's best rune page?

    Sejuani's best rune page has a 83.3% win rate in patch 26.7, which is +32.4% compared to Sejuani's average win rate. This rune setup has a 0.9% pick rate among Sejuani players.

    What keystone should I use on Sejuani?

    Aftershock from the Resolve tree is the best keystone rune for Sejuani in patch 26.7. This keystone synergizes well with Sejuani's kit and provides a 83.3% win rate.

    What is Sejuani's primary rune tree?

    Sejuani's primary rune tree is Resolve. The optimal Resolve runes for Sejuani are Aftershock, Font of Life, Conditioning, and Overgrowth, with Aftershock being the keystone of choice.

    What is Sejuani's secondary rune tree?

    Sejuani's best secondary rune tree is Domination. The recommended Domination runes are Cheap Shot and Ultimate Hunter, which complement Sejuani's Resolve primary tree.

    What are alternative rune setups for Sejuani?

    An alternative Sejuani rune setup uses Grasp of the Undying from the Resolve tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.

    How popular are Sejuani's runes?

    Sejuani's top rune page has a 0.9% pick rate in patch 26.7. This indicates that 0.9% of Sejuani players use the Aftershock setup with Resolve and Domination trees.