Gwen - League of Legends Champion
Win Rate
49.2%
Pick Rate
2.3%

GwenRunes

DFighter
Patch26.14
Matches491,560
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 23, 2026
MethodologyData Methodology

Best Gwen runes for LoL Patch 26.14 - First Strike from the Inspiration tree with Sorcery secondary (62.5% WR, 1.4% pick rate). Gwen's optimal primary runes are First Strike, Cash Back, Triple Tonic, Jack Of All Trades. Secondary tree: Absolute Focus, Gathering Storm.

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Gwen performs best with First Strike as the keystone rune from the Inspiration tree. Gwen's optimal primary runes are First Strike, Cash Back, Triple Tonic, Jack Of All Trades. Gwen's secondary rune tree is Sorcery with Absolute Focus, Gathering Storm. This rune setup achieves a 62.50% win rate (+13.3% win rate difference) with a 1.4% pick rate across 32 Gwen games.
62.5%Win Rate
+13.3%WR Diff
1.4%Pick Rate
First StrikeFirst Strike

Attacks or abilities against an enemy champion within 0.25s of entering champion combat grant 10 gold and First Strike for 3 seconds, causing you to deal 7% extra damage against champions, and granting 50% (35% for ranged champions) of bonus damage dealt as gold.

Cooldown: 25 - 15s

Cash BackCash Back

Get 7.5% Gold back when you purchase Legendary Items.

Triple TonicTriple Tonic

Upon reaching level 3, gain an Elixir of Avarice.
Upon reaching level 6, gain an Elixir of Force.
Upon reaching level 9, gain an Elixir of Skill.

Jack Of All TradesJack Of All Trades

For each different stat gained from items, gain one Jack stack. Each stack grants you 1 Ability Haste.

Gain 10 or 25 bonus Adaptive Force at 5 and 10 stacks, respectively.

Absolute FocusAbsolute Focus

While above 70% health, gain an adaptive bonus of up to 18 Attack Damage or 30 Ability Power (based on level).

Grants 1.8 Attack Damage or 3 Ability Power at level 1.

Gathering StormGathering Storm

Every 10 min gain AP or AD, adaptive.

10 min: + 8 AP or 5 AD
20 min: + 24 AP or 14 AD
30 min: + 48 AP or 29 AD
40 min: + 80 AP or 48 AD
50 min: + 120 AP or 72 AD
60 min: + 168 AP or 101 AD
etc...

This alternative Gwen rune build uses First Strike as the keystone from the Inspiration tree. The primary runes are First Strike, Cash Back, Biscuit Delivery, Jack Of All Trades. Gwen's secondary rune tree is Sorcery with Absolute Focus, Gathering Storm. This setup achieves a 51.89% win rate (+2.7% win rate difference) with a 8.1% pick rate across 185 games.
51.9%Win Rate
+2.7%WR Diff
8.1%Pick Rate
First StrikeFirst Strike

Attacks or abilities against an enemy champion within 0.25s of entering champion combat grant 10 gold and First Strike for 3 seconds, causing you to deal 7% extra damage against champions, and granting 50% (35% for ranged champions) of bonus damage dealt as gold.

Cooldown: 25 - 15s

Cash BackCash Back

Get 7.5% Gold back when you purchase Legendary Items.

Biscuit DeliveryBiscuit Delivery

Biscuit Delivery: Gain a Total Biscuit of Everlasting Will every 2 mins, until 6 min.

Biscuits restore 20 + 2% of your maximum health, increased by up to 100% based on missing Health. Consuming or selling a Biscuit permanently increases your max health by 30.

Jack Of All TradesJack Of All Trades

For each different stat gained from items, gain one Jack stack. Each stack grants you 1 Ability Haste.

Gain 10 or 25 bonus Adaptive Force at 5 and 10 stacks, respectively.

Absolute FocusAbsolute Focus

While above 70% health, gain an adaptive bonus of up to 18 Attack Damage or 30 Ability Power (based on level).

Grants 1.8 Attack Damage or 3 Ability Power at level 1.

Gathering StormGathering Storm

Every 10 min gain AP or AD, adaptive.

10 min: + 8 AP or 5 AD
20 min: + 24 AP or 14 AD
30 min: + 48 AP or 29 AD
40 min: + 80 AP or 48 AD
50 min: + 120 AP or 72 AD
60 min: + 168 AP or 101 AD
etc...

These champions share at least 4 runes with Gwen's recommended rune builds. use similar keystone and secondary runes, making them good alternatives if you enjoy Gwen's playstyle or want to learn champions with familiar rune setups.Zed

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Gwen Runes - Frequently Asked Questions

What are the best Gwen runes in patch 26.14?

The best Gwen runes in patch 26.14 use the Inspiration tree with First Strike, Cash Back, Triple Tonic, and Jack Of All Trades, and the Sorcery tree with Absolute Focus and Gathering Storm. This rune setup achieves a 62.5% win rate with a 1.4% pick rate.

What is the win rate for Gwen's best rune page?

Gwen's best rune page has a 62.5% win rate in patch 26.14, which is +13.3% compared to Gwen's average win rate. This rune setup has a 1.4% pick rate among Gwen players.

What keystone should I use on Gwen?

First Strike from the Inspiration tree is the best keystone rune for Gwen in patch 26.14. This keystone synergizes well with Gwen's kit and provides a 62.5% win rate.

What is Gwen's primary rune tree?

Gwen's primary rune tree is Inspiration. The optimal Inspiration runes for Gwen are First Strike, Cash Back, Triple Tonic, and Jack Of All Trades, with First Strike being the keystone of choice.

What is Gwen's secondary rune tree?

Gwen's best secondary rune tree is Sorcery. The recommended Sorcery runes are Absolute Focus and Gathering Storm, which complement Gwen's Inspiration primary tree.

What are alternative rune setups for Gwen?

An alternative Gwen rune setup uses First Strike from the Inspiration tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.

How popular are Gwen's runes?

Gwen's top rune page has a 1.4% pick rate in patch 26.14. This indicates that 1.4% of Gwen players use the First Strike setup with Inspiration and Sorcery trees.