
Seraphine Runes
The top Seraphine runes in LoL patch 25.23 are Guardian, Font of Life, Second Wind, Revitalize for Seraphine's primary runes. Seraphine's runes in his secondary tree best utilizes Cash Back and Cosmic Insight. These Seraphine rune choices provide the best Seraphine rune build for ranked.


Stage Presence
Every third basic spell will cast twice from Seraphine. Additionally, casting spells near allies grants her bonus magic damage and range on her next basic attack.


High Note
Seraphine deals damage in an area.
Cost:- 60/
- 70/
- 80/
- 90/
- 100
Cooldown:- 8/
- 8/
- 7/
- 7/
- 6
Range:- 900


Surround Sound
Seraphine Shields and Hastes nearby allies. If she is already Shielded she will Heal nearby allies as well.
Cost:- 70/
- 75/
- 80/
- 85/
- 90
Cooldown:- 22
Range:- 800


Beat Drop
Seraphine deals damage and impairs the movement of enemies in a line.
Cost:- 60
Cooldown:- 11/
- 11/
- 10/
- 10/
- 9
Range:- 1300


Encore
Seraphine deals damage and charms enemies hit, refreshing the range with every allied or enemy champion hit.
Cost:- 100
Cooldown:- 160/
- 140/
- 120
Range:- 25000
- Support,
- Mage

Seraphine performs best with Guardian as the keystone rune. The optimal primary runes for Seraphine include Guardian, Font of Life, Second Wind. This rune setup achieves a 1.00% win rate across 1 Seraphine games.
Primary Tree
ResolveThis alternative Seraphine rune build uses Summon Aery as the keystone. This setup provides a different playstyle for Seraphine and achieves a 1.00% win rate. Consider this rune page when facing specific matchups or team compositions.
Primary Tree
SorcerySeraphine Runes - Frequently Asked Questions
What are the best Seraphine runes?
The best Seraphine runes in patch 25.23 are Guardian, Font of Life, Second Wind, and Revitalize for the primary tree, and Cash Back and Cosmic Insight for the secondary tree. These runes provide optimal performance for Seraphine.
What keystone should I use on Seraphine?
Guardian is the best keystone rune for Seraphine. This keystone synergizes well with Seraphine's abilities and provides maximum value in most matchups.
What are Seraphine's secondary runes?
Seraphine's best secondary runes are Cash Back and Cosmic Insight. These secondary runes complement Seraphine's primary rune choices and enhance overall effectiveness.
Can I use different rune setups on Seraphine?
Yes, Seraphine can utilize different rune setups depending on matchup and playstyle. While Guardian is most popular, alternative keystones may work better in specific situations.





































