Annie, League of Legends champion
Win Rate
51.7%
Pick Rate
1.0%
Ban Rate
0.7%

Annie Mid Runes: Keystone & Shards

Annie A TierMageSupport
Patch
26.22
Games
1,928
Lane
Mid
Tier
All Tiers
Last Updated
Nov 14, 2026 UTC
Methodology
Data Methodology

Best Annie Mid runes for LoL Patch 26.22: Electrocute in 82% of games (51.4% win rate) with Sorcery. Every keystone, minor rune and shard by win rate.

Keystone
Electrocute82% of games · 51.4% win rate
Secondary tree
Sorcery75% of games
Shards
Adaptive Force (flex)
Summoner spells
Flash + Ignite72% of games
Ranked games
1,928
Annie performs best with Electrocute as the keystone rune from the Domination tree. Annie's optimal primary runes are Electrocute, Cheap Shot, Grisly Mementos, Relentless Hunter. Annie's secondary rune tree is Sorcery with Absolute Focus, Axiom Arcanist. This rune setup achieves a 54.29% win rate (+2.6% win rate difference) with a 34.3% pick rate across 676 Annie games.
54.3%Win Rate
+2.6%WR Diff
34.3%Pick Rate
Electrocute – League of Legends runeElectrocute

Hitting a champion with 3 separate attacks or abilities within 3s deals bonus adaptive damage.

Damage: 70 - 240 (+0.1 bonus AD, +0.05 AP) damage.
Cooldown: 20s

'We called them the Thunderlords, for to speak of their lightning was to invite disaster.'

Cheap Shot – League of Legends runeCheap Shot

Damaging champions with impaired movement or actions deals 10 - 45 bonus true damage (based on level).

Cooldown: 4s
Activates on damage occurring after the impairment.

Grisly Mementos – League of Legends runeGrisly Mementos

Collect 1 memento on champion takedowns, up to 18 total.

Gain 6 Trinket Haste for each collected. In game modes where vision Trinkets do not exist, instead gain 3 Summoner Spell Haste.

Relentless Hunter – League of Legends runeRelentless Hunter

Gain 8 Move Speed out of combat per Bounty Hunter stack. Bounty Hunter stacks are earned the first time you get a takedown on each enemy champion.

Absolute Focus – League of Legends runeAbsolute Focus

While above 70% health, gain an adaptive bonus of up to 18 Attack Damage or 30 Ability Power (based on level).

Grants 1.8 Attack Damage or 3 Ability Power at level 1.

Axiom Arcanist – League of Legends runeAxiom Arcanist

Your Ultimate has 12% increased damage, healing, and shielding.
(AoE damage is reduced to a 8% increase)

Scoring a takedown on an enemy champion reduces your Ultimate's current cooldown by 7%.

This alternative Annie rune build uses Electrocute as the keystone from the Domination tree. The primary runes are Electrocute, Cheap Shot, Grisly Mementos, Relentless Hunter. Annie's secondary rune tree is Sorcery with Axiom Arcanist, Absolute Focus. This setup achieves a 52.47% win rate (+0.7% win rate difference) with a 8.2% pick rate across 162 games.
52.5%Win Rate
+0.7%WR Diff
8.2%Pick Rate
Electrocute – League of Legends runeElectrocute

Hitting a champion with 3 separate attacks or abilities within 3s deals bonus adaptive damage.

Damage: 70 - 240 (+0.1 bonus AD, +0.05 AP) damage.
Cooldown: 20s

'We called them the Thunderlords, for to speak of their lightning was to invite disaster.'

Cheap Shot – League of Legends runeCheap Shot

Damaging champions with impaired movement or actions deals 10 - 45 bonus true damage (based on level).

Cooldown: 4s
Activates on damage occurring after the impairment.

Grisly Mementos – League of Legends runeGrisly Mementos

Collect 1 memento on champion takedowns, up to 18 total.

Gain 6 Trinket Haste for each collected. In game modes where vision Trinkets do not exist, instead gain 3 Summoner Spell Haste.

Relentless Hunter – League of Legends runeRelentless Hunter

Gain 8 Move Speed out of combat per Bounty Hunter stack. Bounty Hunter stacks are earned the first time you get a takedown on each enemy champion.

Axiom Arcanist – League of Legends runeAxiom Arcanist

Your Ultimate has 12% increased damage, healing, and shielding.
(AoE damage is reduced to a 8% increase)

Scoring a takedown on an enemy champion reduces your Ultimate's current cooldown by 7%.

Absolute Focus – League of Legends runeAbsolute Focus

While above 70% health, gain an adaptive bonus of up to 18 Attack Damage or 30 Ability Power (based on level).

Grants 1.8 Attack Damage or 3 Ability Power at level 1.

These champions share at least 4 runes with Annie's recommended rune builds. use similar keystone and secondary runes, making them good alternatives if you enjoy Annie's playstyle or want to learn champions with familiar rune setups.Anivia
MetaBot Desktop

Auto-import Annie's best runes in champ select

Turn on auto-import and MetaBot Desktop applies the highest win-rate rune page when you pick a champion, adds a MetaBot item set to your shop and sets your summoner spells, keeping your Flash slot.

  • Rune page applied on pick
  • Item set added to your shop
  • Summoners set, Flash kept
MetaBot Desktop's champ select overlay importing runes, items and summoner spells

Every Annie Mid Keystone and Secondary Tree (Patch 26.22)

1,928 games

Annie Mid runs Electrocute in 82% of games, with a 51.4% win rate. Sorcery is the usual secondary tree (75%). Standard stat shards: Adaptive Force (offense), Adaptive Force (flex), Health Scaling (defense).

Keystones

RunePlayersWin RateGames
Electrocute – League of Legends runeElectrocuteMost played82.4%51.4%1,589
Deathfire Touch – League of Legends runeDeathfire Touch12.4%53.6%239
First Strike – League of Legends runeFirst Strike2.2%64.3%42

Secondary trees

RunePlayersWin RateGames
Sorcery – League of Legends runeSorceryMost played74.6%52.4%1,438
Inspiration – League of Legends runeInspiration11.2%47.9%215
Precision – League of Legends runePrecision9.3%49.7%179
Resolve – League of Legends runeResolve3.0%56.1%57

Pick rate is the share of Annie games in this lane that used the rune; options under 40 games are left out. A higher win rate on a rarely picked rune is usually a matchup-specific choice, not a general upgrade.

Annie Minor Runes by Tree

Every minor rune Annie players take, grouped by rune tree, with how often it is picked and how often it wins.

Domination

RunePlayersWin RateGames
Cheap Shot – League of Legends runeCheap ShotMost played71.3%51.4%1,374
Grisly Mementos – League of Legends runeGrisly Mementos69.8%52.0%1,346
Relentless Hunter – League of Legends runeRelentless Hunter61.0%52.0%1,176
Ultimate Hunter – League of Legends runeUltimate Hunter22.5%50.2%434
Taste of Blood – League of Legends runeTaste of Blood13.2%52.0%254
Sixth Sense – League of Legends runeSixth Sense12.7%49.4%245

Sorcery

RunePlayersWin RateGames
Axiom Arcanist – League of Legends runeAxiom ArcanistMost played59.3%52.3%1,143
Absolute Focus – League of Legends runeAbsolute Focus53.6%53.2%1,034
Manaflow Band – League of Legends runeManaflow Band25.7%51.6%496
Scorch – League of Legends runeScorch23.7%52.5%457
Celerity – League of Legends runeCelerity14.8%48.3%286
Transcendence – League of Legends runeTranscendence8.0%56.1%155

Inspiration

RunePlayersWin RateGames
Cosmic Insight – League of Legends runeCosmic InsightMost played11.9%51.1%229
Biscuit Delivery – League of Legends runeBiscuit Delivery6.9%46.6%133
Magical Footwear – League of Legends runeMagical Footwear3.9%59.2%76
Triple Tonic – League of Legends runeTriple Tonic3.6%57.1%70

Precision

RunePlayersWin RateGames
Legend: Haste – League of Legends runeLegend: HasteMost played9.0%49.7%173
Cut Down – League of Legends runeCut Down8.7%49.4%168

Resolve

RunePlayersWin RateGames
Bone Plating – League of Legends runeBone PlatingMost played2.7%58.5%53

Annie Stat Shards

Which stat shards Annie players choose in each of the three shard rows, and the win rate of each.

RunePlayersWin RateGames
Adaptive Force (flex) – League of Legends runeAdaptive Force (flex)Most played84.9%52.0%1,636
Adaptive Force (offense) – League of Legends runeAdaptive Force (offense)69.9%53.3%1,348
Health Scaling (defense) – League of Legends runeHealth Scaling (defense)66.8%52.1%1,287
Health (defense) – League of Legends runeHealth (defense)32.0%50.9%617
Attack Speed (offense) – League of Legends runeAttack Speed (offense)26.1%47.2%504
Move Speed (flex) – League of Legends runeMove Speed (flex)14.7%50.2%283
Ability Haste (offense) – League of Legends runeAbility Haste (offense)3.9%53.9%76
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Annie Runes FAQ - Patch 26.22

What is the best keystone for Annie Mid?

Electrocute: Annie Mid takes it in 82% of ranked games and wins 51.4% of 1,589 games. Alternatives: Deathfire Touch (12%, 53.6%), First Strike (2%, 64.3%).

What stat shards should Annie take?

Most Annie players take Adaptive Force (offense), Adaptive Force (flex), Health Scaling (defense) — one from each shard row.

What are the best Annie runes in patch 26.22?

The best Annie runes in patch 26.22 use the Domination tree with Electrocute, Cheap Shot, Grisly Mementos, and Relentless Hunter, and the Sorcery tree with Absolute Focus and Axiom Arcanist. This rune setup achieves a 54.3% win rate with a 34.3% pick rate.

What is the win rate for Annie's best rune page?

Annie's best rune page has a 54.3% win rate in patch 26.22, which is +2.6% compared to Annie's average win rate. This rune setup has a 34.3% pick rate among Annie players.

What keystone should I use on Annie?

Electrocute from the Domination tree is the best keystone rune for Annie in patch 26.22. This keystone synergizes well with Annie's kit and provides a 54.3% win rate.

What is Annie's primary rune tree?

Annie's primary rune tree is Domination. The optimal Domination runes for Annie are Electrocute, Cheap Shot, Grisly Mementos, and Relentless Hunter, with Electrocute being the keystone of choice.

What is Annie's secondary rune tree?

Annie's best secondary rune tree is Sorcery. The recommended Sorcery runes are Absolute Focus and Axiom Arcanist, which complement Annie's Domination primary tree.

What are alternative rune setups for Annie?

An alternative Annie rune setup uses Electrocute from the Domination tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.

How popular are Annie's runes?

Annie's top rune page has a 34.3% pick rate in patch 26.22. This indicates that 34.3% of Annie players use the Electrocute setup with Domination and Sorcery trees.