
AnnieRunes (Mid)
Best Mid Annie runes for LoL Patch 26.19 - Electrocute from the Domination tree with Inspiration secondary (65.2% WR, 9.3% pick rate). Annie's optimal primary runes are Electrocute, Cheap Shot, Grisly Mementos, Ultimate Hunter. Secondary tree: Biscuit Delivery, Cosmic Insight.
Primary Tree
Domination
ElectrocuteHitting a champion with 3 separate attacks or abilities within 3s deals bonus
Damage: 70 - 240 (+0.1 bonus AD, +0.05 AP) damage.
Cooldown: 20s
'We called them the Thunderlords, for to speak of their lightning was to invite disaster.'
Cheap ShotDamaging champions with impaired movement or actions deals 10 - 45 bonus true damage (based on level).
Cooldown: 4s
Grisly MementosCollect 1 memento on champion
Gain 6 Trinket Haste for each collected. In game modes where vision Trinkets do not exist, instead gain 3 Summoner Spell Haste.
Ultimate HunterYour ultimate gains
Biscuit DeliveryBiscuit Delivery: Gain a Total Biscuit of Everlasting Will every 2 mins, until 6 min.
Biscuits restore 20 + 2% of your maximum health, increased by up to 100% based on missing Health. Consuming or selling a Biscuit permanently increases your max health by 30.
Cosmic Insight+
+
Primary Tree
Domination
ElectrocuteHitting a champion with 3 separate attacks or abilities within 3s deals bonus
Damage: 70 - 240 (+0.1 bonus AD, +0.05 AP) damage.
Cooldown: 20s
'We called them the Thunderlords, for to speak of their lightning was to invite disaster.'
Cheap ShotDamaging champions with impaired movement or actions deals 10 - 45 bonus true damage (based on level).
Cooldown: 4s
Grisly MementosCollect 1 memento on champion
Gain 6 Trinket Haste for each collected. In game modes where vision Trinkets do not exist, instead gain 3 Summoner Spell Haste.
Relentless HunterGain
Absolute FocusWhile above 70% health, gain an
Grants 1.8 Attack Damage or 3 Ability Power at level 1.
Axiom ArcanistYour Ultimate has 12% increased damage, healing, and shielding.
(AoE damage is reduced to a 8% increase)
Scoring a takedown on an enemy champion reduces your Ultimate's current cooldown by 7%.
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Annie Runes - Frequently Asked Questions
What are the best Annie runes in patch 26.19?
The best Annie runes in patch 26.19 use the Domination tree with Electrocute, Cheap Shot, Grisly Mementos, and Ultimate Hunter, and the Inspiration tree with Biscuit Delivery and Cosmic Insight. This rune setup achieves a 65.2% win rate with a 9.3% pick rate.
What is the win rate for Annie's best rune page?
Annie's best rune page has a 65.2% win rate in patch 26.19, which is +7.7% compared to Annie's average win rate. This rune setup has a 9.3% pick rate among Annie players.
What keystone should I use on Annie?
Electrocute from the Domination tree is the best keystone rune for Annie in patch 26.19. This keystone synergizes well with Annie's kit and provides a 65.2% win rate.
What is Annie's primary rune tree?
Annie's primary rune tree is Domination. The optimal Domination runes for Annie are Electrocute, Cheap Shot, Grisly Mementos, and Ultimate Hunter, with Electrocute being the keystone of choice.
What is Annie's secondary rune tree?
Annie's best secondary rune tree is Inspiration. The recommended Inspiration runes are Biscuit Delivery and Cosmic Insight, which complement Annie's Domination primary tree.
What are alternative rune setups for Annie?
An alternative Annie rune setup uses Electrocute from the Domination tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.
How popular are Annie's runes?
Annie's top rune page has a 9.3% pick rate in patch 26.19. This indicates that 9.3% of Annie players use the Electrocute setup with Domination and Inspiration trees.





























