Lissandra, League of Legends champion
Win Rate
49.3%
Pick Rate
2.2%
Ban Rate
2.2%

Lissandra Mid Runes: Keystone & Shards

Lissandra C TierMage
Patch
26.20
Games
4,331
Lane
Mid
Tier
All Tiers
Last Updated
Oct 23, 2026 UTC
Methodology
Data Methodology

Best Mid Lissandra runes for LoL Patch 26.20 - Arcane Comet from the Sorcery tree with Domination secondary (49.8% WR, 28.1% pick rate). Lissandra's optimal primary runes are Arcane Comet, Manaflow Band, Transcendence, Scorch. Secondary tree: Cheap Shot, Ultimate Hunter.

Lissandra performs best with Arcane Comet as the keystone rune from the Sorcery tree. Lissandra's optimal primary runes are Arcane Comet, Manaflow Band, Transcendence, Scorch. Lissandra's secondary rune tree is Domination with Cheap Shot, Ultimate Hunter. This rune setup achieves a 49.84% win rate (+0.5% win rate difference) with a 28.1% pick rate across 1,216 Lissandra games.
49.8%Win Rate
+0.5%WR Diff
28.1%Pick Rate
Arcane CometArcane Comet

Damaging a champion with an ability hurls a comet at their location, dealing increased damage based on distance.

Adaptive Damage: 15 - 100 based on level (+0.05 AP and +0.1 bonus AD)
Cooldown: 20 - 8s

Damage amplification scales up to 100% at 750 range.

Manaflow BandManaflow Band

Hitting an enemy champion with an ability permanently increases your maximum mana by 25, up to 250 mana.

After reaching 250 bonus mana, restore 1% of your missing mana every 5 seconds.

Cooldown: 15 seconds

TranscendenceTranscendence

Gain bonuses upon reaching the following levels:
Level 5: +5 Ability Haste
Level 8: +5 Ability Haste
Level 11: On Champion takedown, reduce the remaining cooldown of basic abilities by 20%.

ScorchScorch

Your next damaging ability hit sets champions on fire dealing 20 - 40 bonus magic damage based on level after 1s.

Cooldown: 10s

Cheap ShotCheap Shot

Damaging champions with impaired movement or actions deals 10 - 45 bonus true damage (based on level).

Cooldown: 4s
Activates on damage occurring after the impairment.

Ultimate HunterUltimate Hunter

Your ultimate gains 6 Ability Haste, plus an additional 5 Ability Haste per Bounty Hunter stack. Bounty Hunter stacks are earned the first time you get a takedown on each enemy champion.

This alternative Lissandra rune build uses Electrocute as the keystone from the Domination tree. The primary runes are Electrocute, Cheap Shot, Grisly Mementos, Ultimate Hunter. Lissandra's secondary rune tree is Sorcery with Manaflow Band, Transcendence. This setup achieves a 48.16% win rate (-1.2% win rate difference) with a 43.3% pick rate across 1,877 games.
48.2%Win Rate
-1.2%WR Diff
43.3%Pick Rate
ElectrocuteElectrocute

Hitting a champion with 3 separate attacks or abilities within 3s deals bonus adaptive damage.

Damage: 70 - 240 (+0.1 bonus AD, +0.05 AP) damage.
Cooldown: 20s

'We called them the Thunderlords, for to speak of their lightning was to invite disaster.'

Cheap ShotCheap Shot

Damaging champions with impaired movement or actions deals 10 - 45 bonus true damage (based on level).

Cooldown: 4s
Activates on damage occurring after the impairment.

Grisly MementosGrisly Mementos

Collect 1 memento on champion takedowns, up to 18 total.

Gain 6 Trinket Haste for each collected. In game modes where vision Trinkets do not exist, instead gain 3 Summoner Spell Haste.

Ultimate HunterUltimate Hunter

Your ultimate gains 6 Ability Haste, plus an additional 5 Ability Haste per Bounty Hunter stack. Bounty Hunter stacks are earned the first time you get a takedown on each enemy champion.

Manaflow BandManaflow Band

Hitting an enemy champion with an ability permanently increases your maximum mana by 25, up to 250 mana.

After reaching 250 bonus mana, restore 1% of your missing mana every 5 seconds.

Cooldown: 15 seconds

TranscendenceTranscendence

Gain bonuses upon reaching the following levels:
Level 5: +5 Ability Haste
Level 8: +5 Ability Haste
Level 11: On Champion takedown, reduce the remaining cooldown of basic abilities by 20%.

These champions share at least 4 runes with Lissandra's recommended rune builds. use similar keystone and secondary runes, making them good alternatives if you enjoy Lissandra's playstyle or want to learn champions with familiar rune setups.Vex, Vel'Koz, Lux, Annie, Aurora and 5 others

Every Lissandra Mid Keystone and Secondary Tree (Patch 26.20)

4,171 games

Lissandra Mid runs Electrocute in 61% of games, with a 49.2% win rate. Sorcery is the usual secondary tree (52%). Standard stat shards: Adaptive Force (offense), Adaptive Force (flex), Health Scaling (defense).

Keystones

RunePlayersWin RateGames
ElectrocuteElectrocuteMost played61.0%49.2%2,543
Arcane CometArcane Comet34.9%51.0%1,454
Deathfire TouchDeathfire Touch1.8%43.2%74
Dark HarvestDark Harvest1.2%44.0%50

Secondary trees

RunePlayersWin RateGames
SorcerySorceryMost played52.3%49.0%2,182
DominationDomination32.5%51.0%1,354
InspirationInspiration9.9%48.7%411
ResolveResolve3.5%45.9%148
PrecisionPrecision1.8%48.7%76

Pick rate is the share of Lissandra games in this lane that used the rune; options under 40 games are left out. A higher win rate on a rarely picked rune is usually a matchup-specific choice, not a general upgrade.

Lissandra Minor Runes by Tree

Every minor rune Lissandra players take, grouped by rune tree, with how often it is picked and how often it wins.

Domination

RunePlayersWin RateGames
Ultimate HunterUltimate HunterMost played94.0%49.8%3,920
Cheap ShotCheap Shot92.8%49.7%3,871
Grisly MementosGrisly Mementos60.0%48.9%2,503
Sixth SenseSixth Sense1.6%55.2%67
Taste of BloodTaste of Blood1.1%54.5%44

Sorcery

RunePlayersWin RateGames
TranscendenceTranscendenceMost played85.0%49.6%3,544
Manaflow BandManaflow Band82.4%49.4%3,438
ScorchScorch37.6%50.2%1,567
Axiom ArcanistAxiom Arcanist4.9%52.9%206
Gathering StormGathering Storm4.2%54.0%176
Absolute FocusAbsolute Focus1.2%38.8%49

Inspiration

RunePlayersWin RateGames
Cosmic InsightCosmic InsightMost played9.4%49.5%390
Biscuit DeliveryBiscuit Delivery8.8%46.7%366

Resolve

RunePlayersWin RateGames
Bone PlatingBone PlatingMost played3.1%48.9%131
OvergrowthOvergrowth2.5%46.6%103

Precision

RunePlayersWin RateGames
Presence of MindPresence of MindMost played1.1%44.4%45

Lissandra Stat Shards

Which stat shards Lissandra players choose in each of the three shard rows, and the win rate of each.

RunePlayersWin RateGames
Adaptive Force (flex)Adaptive Force (flex)Most played97.5%49.6%4,068
Adaptive Force (offense)Adaptive Force (offense)92.9%49.3%3,876
Health Scaling (defense)Health Scaling (defense)90.9%49.4%3,790
Health (defense)Health (defense)6.0%49.6%250
Attack Speed (offense)Attack Speed (offense)5.3%53.2%220
Tenacity and Slow Resist (defense)Tenacity and Slow Resist (defense)3.1%51.1%131
Move Speed (flex)Move Speed (flex)1.9%45.7%81
Ability Haste (offense)Ability Haste (offense)1.8%52.0%75
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Lissandra Runes FAQ - Patch 26.20

What is the best keystone for Lissandra Mid?

Electrocute: Lissandra Mid takes it in 61% of ranked games and wins 49.2% of 2,543 games. Alternatives: Arcane Comet (35%, 51.0%), Deathfire Touch (2%, 43.2%).

What stat shards should Lissandra take?

Most Lissandra players take Adaptive Force (offense), Adaptive Force (flex), Health Scaling (defense) — one from each shard row.

What are the best Lissandra runes in patch 26.20?

The best Lissandra runes in patch 26.20 use the Sorcery tree with Arcane Comet, Manaflow Band, Transcendence, and Scorch, and the Domination tree with Cheap Shot and Ultimate Hunter. This rune setup achieves a 49.8% win rate with a 28.1% pick rate.

What is the win rate for Lissandra's best rune page?

Lissandra's best rune page has a 49.8% win rate in patch 26.20, which is +0.5% compared to Lissandra's average win rate. This rune setup has a 28.1% pick rate among Lissandra players.

What keystone should I use on Lissandra?

Arcane Comet from the Sorcery tree is the best keystone rune for Lissandra in patch 26.20. This keystone synergizes well with Lissandra's kit and provides a 49.8% win rate.

What is Lissandra's primary rune tree?

Lissandra's primary rune tree is Sorcery. The optimal Sorcery runes for Lissandra are Arcane Comet, Manaflow Band, Transcendence, and Scorch, with Arcane Comet being the keystone of choice.

What is Lissandra's secondary rune tree?

Lissandra's best secondary rune tree is Domination. The recommended Domination runes are Cheap Shot and Ultimate Hunter, which complement Lissandra's Sorcery primary tree.

What are alternative rune setups for Lissandra?

An alternative Lissandra rune setup uses Electrocute from the Domination tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.

How popular are Lissandra's runes?

Lissandra's top rune page has a 28.1% pick rate in patch 26.20. This indicates that 28.1% of Lissandra players use the Arcane Comet setup with Sorcery and Domination trees.