Lissandra - League of Legends Champion
Win Rate
51.3%
Pick Rate
2.2%

LissandraRunes

AMage
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 19, 2026
MethodologyData Methodology

Best Lissandra runes for LoL Patch 26.7 - Arcane Comet from the Sorcery tree with Domination secondary (75.0% WR, 0.5% pick rate). Lissandra's optimal primary runes are Arcane Comet, Manaflow Band, Transcendence, Scorch. Secondary tree: Cheap Shot, Ultimate Hunter.

Lissandra performs best with Arcane Comet as the keystone rune from the Sorcery tree. Lissandra's optimal primary runes are Arcane Comet, Manaflow Band, Transcendence, Scorch. Lissandra's secondary rune tree is Domination with Cheap Shot, Ultimate Hunter. This rune setup achieves a 75.00% win rate (+23.7% win rate difference) with a 0.5% pick rate across 20 Lissandra games.
75.0%Win Rate
+23.7%WR Diff
0.5%Pick Rate
Arcane CometArcane Comet

Damaging a champion with an ability hurls a comet at their location, or, if Arcane Comet is on cooldown, reduces its remaining cooldown.

Adaptive Damage: 30 - 130 based on level (+0.05 AP and +0.1 bonus AD)
Cooldown: 20 - 8s

Cooldown Reduction:
Single Target: 20%.
Area of Effect: 10%.
Damage over Time: 5%.

Manaflow BandManaflow Band

Hitting an enemy champion with an ability permanently increases your maximum mana by 25, up to 250 mana.

After reaching 250 bonus mana, restore 1% of your missing mana every 5 seconds.

Cooldown: 15 seconds

TranscendenceTranscendence

Gain bonuses upon reaching the following levels:
Level 5: +5 Ability Haste
Level 8: +5 Ability Haste
Level 11: On Champion takedown, reduce the remaining cooldown of basic abilities by 20%.

ScorchScorch

Your next damaging ability hit sets champions on fire dealing 20 - 40 bonus magic damage based on level after 1s.

Cooldown: 10s

Cheap ShotCheap Shot

Damaging champions with impaired movement or actions deals 10 - 45 bonus true damage (based on level).

Cooldown: 4s
Activates on damage occurring after the impairment.

Ultimate HunterUltimate Hunter

Your ultimate gains 6 Ability Haste, plus an additional 5 Ability Haste per Bounty Hunter stack. Bounty Hunter stacks are earned the first time you get a takedown on each enemy champion.

This alternative Lissandra rune build uses Arcane Comet as the keystone from the Sorcery tree. The primary runes are Arcane Comet, Manaflow Band, Transcendence, Scorch. Lissandra's secondary rune tree is Resolve with Bone Plating, Overgrowth. This setup achieves a 67.80% win rate (+16.5% win rate difference) with a 1.4% pick rate across 59 games.
67.8%Win Rate
+16.5%WR Diff
1.4%Pick Rate
Arcane CometArcane Comet

Damaging a champion with an ability hurls a comet at their location, or, if Arcane Comet is on cooldown, reduces its remaining cooldown.

Adaptive Damage: 30 - 130 based on level (+0.05 AP and +0.1 bonus AD)
Cooldown: 20 - 8s

Cooldown Reduction:
Single Target: 20%.
Area of Effect: 10%.
Damage over Time: 5%.

Manaflow BandManaflow Band

Hitting an enemy champion with an ability permanently increases your maximum mana by 25, up to 250 mana.

After reaching 250 bonus mana, restore 1% of your missing mana every 5 seconds.

Cooldown: 15 seconds

TranscendenceTranscendence

Gain bonuses upon reaching the following levels:
Level 5: +5 Ability Haste
Level 8: +5 Ability Haste
Level 11: On Champion takedown, reduce the remaining cooldown of basic abilities by 20%.

ScorchScorch

Your next damaging ability hit sets champions on fire dealing 20 - 40 bonus magic damage based on level after 1s.

Cooldown: 10s

Bone PlatingBone Plating

After taking damage from an enemy champion, the next 3 spells or attacks you receive from them deal 30-60 (based on level) less damage.

Duration: 1.5s
Cooldown: 55s

OvergrowthOvergrowth

Absorb life essence from monsters or enemy minions that die near you, permanently gaining 3 maximum health for every 8.

When you've absorbed 120 monsters or enemy minions, gain an additional 3.5% maximum health.

These champions share at least 4 runes with Lissandra's recommended rune builds. use similar keystone and secondary runes, making them good alternatives if you enjoy Lissandra's playstyle or want to learn champions with familiar rune setups.Vel'Koz, Seraphine, Fiddlesticks, Malphite, Brand and 5 others

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Lissandra Runes - Frequently Asked Questions

What are the best Lissandra runes in patch 26.7?

The best Lissandra runes in patch 26.7 use the Sorcery tree with Arcane Comet, Manaflow Band, Transcendence, and Scorch, and the Domination tree with Cheap Shot and Ultimate Hunter. This rune setup achieves a 75.0% win rate with a 0.5% pick rate.

What is the win rate for Lissandra's best rune page?

Lissandra's best rune page has a 75.0% win rate in patch 26.7, which is +23.7% compared to Lissandra's average win rate. This rune setup has a 0.5% pick rate among Lissandra players.

What keystone should I use on Lissandra?

Arcane Comet from the Sorcery tree is the best keystone rune for Lissandra in patch 26.7. This keystone synergizes well with Lissandra's kit and provides a 75.0% win rate.

What is Lissandra's primary rune tree?

Lissandra's primary rune tree is Sorcery. The optimal Sorcery runes for Lissandra are Arcane Comet, Manaflow Band, Transcendence, and Scorch, with Arcane Comet being the keystone of choice.

What is Lissandra's secondary rune tree?

Lissandra's best secondary rune tree is Domination. The recommended Domination runes are Cheap Shot and Ultimate Hunter, which complement Lissandra's Sorcery primary tree.

What are alternative rune setups for Lissandra?

An alternative Lissandra rune setup uses Arcane Comet from the Sorcery tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.

How popular are Lissandra's runes?

Lissandra's top rune page has a 0.5% pick rate in patch 26.7. This indicates that 0.5% of Lissandra players use the Arcane Comet setup with Sorcery and Domination trees.