Cassiopeia - League of Legends Champion
Win Rate
46.3%
Pick Rate
0.9%

Cassiopeiavs Vex

FMage
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 7, 2026
MethodologyData Methodology

Cassiopeia vs Vex is a decisive matchup in LoL patch 26.11. Vex wins with a 54.8% win rate (+9.7%) over Cassiopeia based on 31 games. Cassiopeia wins the early laning phase while Vex scales better into the late game. Below you'll find the best Cassiopeia build, runes, laning stats, and strategies for the Cassiopeia vs Vex matchup.

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Cassiopeia Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Cassiopeia performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Cassiopeia - 45.2% win rate in this matchup
Cassiopeia
45.2% WR
VS
Vex vs Cassiopeia matchup - 54.8% win rate
Vex
54.8% WR

Who Wins the Cassiopeia vs Vex Matchup?

Vex wins the Cassiopeia vs Vex matchup
Winner
Vex
Matches: 31
45.2%
Win Rate
54.8%
5.9
CS / min
6.0
771
DMG / min
985
12,569
Gold / game
13,020
275
Heal / min
96
574
DMG Mitigated / min
555
1.2
CC / min
1.1
60.0%
Early Game WR
40.0%
38.1%
Late Game WR
61.9%

Cassiopeia vs Vex Matchup Summary

The Cassiopeia vs Vex matchup is a decisive matchup in League of Legends ranked play. Based on 31 recent matches analyzed, Vex wins with a 54.8% win rate compared to Cassiopeia's 45.2%, giving Vex a 9.7 percentage point advantage. Game phase dynamics play a critical role here: Cassiopeia controls the early laning stage, but Vex outscales as the game goes longer. The matchup shifts dramatically depending on game length — Cassiopeia needs to press advantages before Vex reaches their power spikes, while Vex should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Cassiopeia leads by 198 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Vex has a strong advantage in this matchup. Cassiopeia players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Vex overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Cassiopeia vs Vex Laning Phase Breakdown

Vex wins the laning phase against Cassiopeia in League of Legends

Vex is favored during the laning phase against Cassiopeia, winning 3 out of 5 key stat categories. Vex holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
5.9Cassiopeia
6.0Vex
Cassiopeia and Vex farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
771Cassiopeia
985Vex
Vex heavily out-damages Cassiopeia by 214 DMG/min, dominating both short trades and all-in fights. Cassiopeia should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vex's sustained damage advantage take over.
Economy
12,569Cassiopeia
13,020Vex
Vex earns 451 more gold per game than Cassiopeia, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Vex slightly faster item completions.
Utility
1.2Cassiopeia
1.1Vex
Both Cassiopeia and Vex provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
849Cassiopeia
651Vex
Cassiopeia vastly out-sustains Vex, healing and mitigating 198 more damage per minute. This massive durability gap means Cassiopeia can absorb significant punishment and remain in lane while Vex is forced to recall. Building grievous wounds early is essential for Vex, and focusing on burst trade patterns rather than sustained fights is critical.

Best Cassiopeia Build Against Vex

Swiftmarch is the optimal boots choice against Vex, providing the mobility and stats Cassiopeia needs most in this matchup. The top-performing core items for Cassiopeia against Vex are Rod of Ages, Liandry's Torment and Rylai's Crystal Scepter. This combination gives Cassiopeia an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 80.0% win rate across 5 games — well above average and making it the top item path against Vex. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Cassiopeia vs Vex matchup.

Early Game vs Late Game

Early Game
Cassiopeia
60.0%
+20.0% advantage
Cassiopeia early game win rateCassiopeia60.0%
Vex early game win rateVex40.0%
Late Game
Vex
61.9%
+23.8% advantage
Cassiopeia late game win rateCassiopeia38.1%
Vex late game win rateVex61.9%

Cassiopeia dominates the early game (first 15 minutes) with a commanding 60.0% win rate — a 20.0 percentage point lead over Vex. This lopsided early game means Cassiopeia can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Vex is far superior in the late game (25+ minutes), boasting a 61.9% win rate — 23.8 points above Cassiopeia. Extended games heavily favor Vex, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Cassiopeia must aggressively press their early advantage and close out the game before Vex reaches their scaling breakpoints. If Vex survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Cassiopeia Runes Against Vex

Sorcery rune tree - Cassiopeia primary runes vs VexSorcery
Deathfire Touch - best Cassiopeia rune vs VexManaflow Band - best Cassiopeia rune vs VexTranscendence - best Cassiopeia rune vs VexScorch - best Cassiopeia rune vs Vex
Precision rune tree - Cassiopeia secondary runes vs VexPrecision
Presence of Mind - best Cassiopeia rune vs VexCoup de Grace - best Cassiopeia rune vs Vex
100.0% WR

The Sorcery and Precision rune setup gives Cassiopeia the best tools to compete against Vex in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Cassiopeia matchup data for League of Legends patch 26.11. The table below shows Cassiopeia's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Cassiopeia build, runes, laning stats, and early vs late game analysis for that specific matchup.

Cassiopeia matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
47.54%616.383512,01164.0%36.1%
52.17%466.891312,15252.6%51.9%
48.65%376.789410,72047.4%50.0%
45.45%336.577611,98138.5%50.0%
46.88%326.685810,85138.1%63.6%
45.16%316.381210,57140.0%50.0%
51.61%317.196810,34854.5%44.4%
45.16%315.977112,56960.0%38.1%
64.52%316.792111,76266.7%62.5%
62.07%296.784312,31953.3%71.4%
42.86%286.974011,66242.9%42.9%
65.22%236.188411,04770.0%61.5%
34.78%236.178710,81440.0%30.8%
34.78%236.274110,91040.0%30.8%
31.82%226.581112,22950.0%21.4%
47.62%216.66699,96927.3%70.0%
66.67%217.095612,82280.0%62.5%
66.67%215.777111,60350.0%76.9%
60.00%206.872411,51850.0%70.0%
47.37%196.474910,42344.4%50.0%
63.16%196.489311,54970.0%55.6%
58.82%176.885811,94360.0%57.1%
52.94%176.592511,50037.5%66.7%
52.94%176.877410,92050.0%55.6%
82.35%176.789111,59488.9%75.0%
47.06%176.086412,19033.3%54.5%
37.50%166.688212,07240.0%36.4%
33.33%156.783512,4600.0%45.5%
66.67%155.781512,12850.0%77.8%
50.00%145.57939,64840.0%55.6%
71.43%146.671811,58380.0%66.7%
57.14%146.68888,74677.8%20.0%
42.86%147.096513,93966.7%25.0%
61.54%136.694413,07640.0%75.0%
33.33%127.391010,99440.0%28.6%
41.67%126.41,04012,89060.0%28.6%
33.33%126.679113,559100.0%27.3%
45.45%116.774611,84125.0%57.1%
18.18%116.278612,0890.0%28.6%
45.45%116.085011,82550.0%42.9%
63.64%115.790313,10766.7%62.5%
27.27%116.474611,72020.0%33.3%
36.36%116.596014,27050.0%28.6%
20.00%106.672610,42428.6%0.0%
40.00%106.398414,52250.0%37.5%
11.11%96.36538,76420.0%0.0%
44.44%96.987211,90440.0%50.0%
33.33%96.372412,71366.7%16.7%
44.44%96.41,27812,86950.0%42.9%
55.56%96.477611,32550.0%60.0%
55.56%96.588712,6850.0%62.5%
66.67%96.493714,897100.0%57.1%
25.00%87.380213,09033.3%20.0%
37.50%86.584312,21733.3%40.0%
57.14%75.989212,35666.7%50.0%
28.57%77.292414,4480.0%33.3%
42.86%76.277111,59450.0%33.3%
14.29%76.891611,0350.0%25.0%
71.43%76.086011,651100.0%50.0%
28.57%75.97388,49533.3%0.0%
66.67%66.592613,9850.0%100.0%
66.67%66.887313,102100.0%50.0%
33.33%66.863510,69750.0%25.0%
50.00%66.276512,03966.7%33.3%
50.00%66.765310,17766.7%33.3%
50.00%66.599812,680100.0%25.0%
60.00%56.367511,35250.0%66.7%
40.00%57.41,03413,86250.0%33.3%
20.00%58.176511,22633.3%0.0%
40.00%56.01,36511,71250.0%33.3%
40.00%55.87258,657100.0%25.0%
80.00%55.568410,127100.0%50.0%
20.00%57.31,04410,50033.3%0.0%
80.00%56.987910,244100.0%66.7%
20.00%56.27839,07950.0%0.0%
60.00%57.889613,847100.0%50.0%
40.00%55.071411,2290.0%50.0%

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Cassiopeia vs Vex - Frequently Asked Questions

How does Cassiopeia do against Vex in League of Legends?

Vex wins the Cassiopeia vs Vex matchup with a 54.8% win rate compared to Cassiopeia's 45.2%, a 9.7 percentage point difference. This data is based on 31 recent ranked games in patch 26.11.

How does Cassiopeia do against Vex in the early game?

In the early game, Cassiopeia has the advantage against Vex with a 60.0% win rate versus 40.0%. Cassiopeia players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Cassiopeia do against Vex in the late game?

In the late game, Vex takes over the Cassiopeia vs Vex matchup with a 61.9% win rate compared to 38.1%. Vex scales better into team fights and objective contests after 25 minutes.

Who wins the Cassiopeia vs Vex matchup?

Vex wins the matchup against Cassiopeia with a 54.8% win rate in League of Legends patch 26.11. The 9.7 percentage point advantage means Vex is significantly favored in this lane matchup based on 31 games analyzed.

What is the best Cassiopeia build against Vex?

The best Cassiopeia build against Vex includes Rod of Ages, Liandry's Torment, Rylai's Crystal Scepter with Swiftmarch. This build achieves a 80.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Cassiopeia runes against Vex?

The best Cassiopeia runes against Vex use the Sorcery primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Cassiopeia vs Vex matchup. See the full rune breakdown in the matchup comparison above.

Does Cassiopeia counter Vex?

No, Cassiopeia struggles against Vex with only a 45.2% win rate. Vex has the advantage in this matchup. Cassiopeia players should focus on safe farming and avoiding extended trades to minimize Vex's lead.

How do I play Cassiopeia against Vex?

When playing Cassiopeia against Vex, play cautiously and avoid Vex's power spikes. Look for jungle assistance and team-dependent plays since Vex has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.