Miss Fortune - League of Legends Champion
Win Rate
51.6%
Pick Rate
7.6%

Miss Fortunevs Seraphine

SMarksmanMage
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 21, 2026
MethodologyData Methodology

Miss Fortune vs Seraphine is a decisive matchup in LoL patch 26.7. Seraphine wins with a 62.5% win rate (+25.0%) over Miss Fortune based on 32 games. Seraphine holds the advantage in both the early and late game. Below you'll find the best Miss Fortune build, runes, laning stats, and strategies for the Miss Fortune vs Seraphine matchup.

Miss Fortune Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Miss Fortune performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Seraphine - 37.5% win rateSeraphine(37.5%)
Miss Fortune - 37.5% win rate in this matchup
Miss Fortune
37.5% WR
VS
Seraphine vs Miss Fortune matchup - 62.5% win rate
Seraphine
62.5% WR

Who Wins the Miss Fortune vs Seraphine Matchup?

Seraphine wins the Miss Fortune vs Seraphine matchup
Winner
Seraphine
Matches: 32
37.5%
Win Rate
62.5%
5.2
CS / min
4.4
867
DMG / min
663
13,525
Gold / game
12,148
158
Heal / min
299
443
DMG Mitigated / min
440
0.4
CC / min
1.3
38.5%
Early Game WR
61.5%
36.8%
Late Game WR
63.2%

Miss Fortune vs Seraphine Matchup Summary

The Miss Fortune vs Seraphine matchup is a decisive matchup in League of Legends ranked play. Based on 32 recent matches analyzed, Seraphine wins with a 62.5% win rate compared to Miss Fortune's 37.5%, giving Seraphine a 25.0 percentage point advantage. Seraphine dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Miss Fortune players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Seraphine leads by 0.9s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Seraphine has a strong advantage in this matchup. Miss Fortune players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Seraphine overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Miss Fortune vs Seraphine Laning Phase Breakdown

Miss Fortune wins the laning phase against Seraphine in League of Legends

Miss Fortune is favored during the laning phase against Seraphine, winning 3 out of 5 key stat categories. Miss Fortune holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
5.2Miss Fortune
4.4Seraphine
Miss Fortune significantly out-farms Seraphine by 0.8 CS per minute, accumulating an estimated 13 CS lead by mid game. This substantial farming gap gives Miss Fortune a major gold advantage and earlier item completions. Seraphine players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
867Miss Fortune
663Seraphine
Miss Fortune heavily out-damages Seraphine by 203 DMG/min, dominating both short trades and all-in fights. Seraphine should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Miss Fortune's sustained damage advantage take over.
Economy
13,525Miss Fortune
12,148Seraphine
Miss Fortune generates a commanding 1,377 more gold per game than Seraphine. This substantial economic advantage means Miss Fortune consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Seraphine should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.4Miss Fortune
1.3Seraphine
Seraphine brings significantly more crowd control than Miss Fortune, with 0.9 more seconds of CC per minute. This large utility gap makes Seraphine far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Miss Fortune should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
601Miss Fortune
739Seraphine
Seraphine heals and mitigates 138 more damage per minute than Miss Fortune, providing moderate extra durability. This sustain edge allows Seraphine to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Miss Fortune.

Best Miss Fortune Build Against Seraphine

Ionian Boots of Lucidity is the optimal boots choice against Seraphine, providing the mobility and stats Miss Fortune needs most in this matchup. The top-performing core items for Miss Fortune against Seraphine are Luden's Echo, Cryptbloom and Blackfire Torch. This combination gives Miss Fortune an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Miss Fortune vs Seraphine matchup.

Early Game vs Late Game

Early Game
Seraphine
61.5%
+23.1% advantage
Miss Fortune early game win rateMiss Fortune38.5%
Seraphine early game win rateSeraphine61.5%
Late Game
Seraphine
63.2%
+26.3% advantage
Miss Fortune late game win rateMiss Fortune36.8%
Seraphine late game win rateSeraphine63.2%

Seraphine dominates the early game (first 15 minutes) with a commanding 61.5% win rate — a 23.1 percentage point lead over Miss Fortune. This lopsided early game means Seraphine can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Seraphine is far superior in the late game (25+ minutes), boasting a 63.2% win rate — 26.3 points above Miss Fortune. Extended games heavily favor Seraphine, whose kit and scaling make them a dominant force in team fights and objective control.

Seraphine holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Miss Fortune players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Miss Fortune Runes Against Seraphine

Precision rune tree - Miss Fortune primary runes vs SeraphinePrecision
Press the Attack - best Miss Fortune rune vs SeraphinePresence of Mind - best Miss Fortune rune vs SeraphineLegend: Bloodline - best Miss Fortune rune vs SeraphineCoup de Grace - best Miss Fortune rune vs Seraphine
Inspiration rune tree - Miss Fortune secondary runes vs SeraphineInspiration
Cosmic Insight - best Miss Fortune rune vs SeraphineBiscuit Delivery - best Miss Fortune rune vs Seraphine
100.0% WR

The Precision and Inspiration rune setup gives Miss Fortune the best tools to compete against Seraphine in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Miss Fortune matchup data for League of Legends patch 26.7. The table below shows Miss Fortune's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Miss Fortune build, runes, laning stats, and early vs late game analysis for that specific matchup.

Miss Fortune matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
51.18%9326.486314,62251.4%51.0%
47.82%6886.485714,11246.4%49.0%
51.53%6546.491614,83850.5%52.2%
51.90%6326.386314,64551.6%52.1%
47.56%4506.590315,03643.8%49.7%
54.96%3936.592314,75548.5%59.8%
50.44%3416.490914,20646.1%54.6%
50.99%3026.590714,43052.5%49.7%
46.77%2636.688314,88153.6%41.7%
54.44%2486.487814,27354.3%54.5%
45.15%2376.283714,33048.5%42.6%
48.80%2096.287214,61245.1%52.3%
55.14%1856.486214,22960.0%51.0%
53.85%1826.285213,84952.8%55.0%
52.07%1696.687315,10855.4%50.0%
59.01%1616.488214,09556.6%61.2%
48.67%1506.590214,83148.3%48.9%
49.62%1336.186313,60847.0%52.2%
49.12%1146.390513,91746.4%51.7%
50.55%916.790114,26345.5%55.3%
42.70%896.484212,90540.9%44.4%
44.71%856.292115,07346.9%43.4%
63.10%846.698816,02768.4%58.7%
52.56%786.272014,00854.8%51.1%
62.16%746.11,07914,57758.1%65.1%
48.57%706.495415,38061.5%40.9%
44.93%696.379114,05935.5%52.6%
56.06%666.185414,05665.5%48.6%
57.69%526.484315,49355.6%58.8%
50.00%505.766811,63748.1%52.2%
58.97%396.598115,64653.3%62.5%
54.29%356.699114,90053.3%55.0%
37.50%325.286713,52538.5%36.8%
56.00%255.583011,70257.1%54.5%
36.36%226.389115,99837.5%35.7%
52.63%196.491116,54233.3%70.0%
66.67%184.090512,82954.5%85.7%
58.82%175.882013,41257.1%60.0%
64.71%176.794312,68854.5%83.3%
31.25%166.281113,90637.5%25.0%
23.08%132.484411,29325.0%22.2%
38.46%136.36279,50130.0%66.7%
61.54%136.791212,67860.0%66.7%
46.15%136.791013,36450.0%44.4%
50.00%124.898711,97083.3%16.7%
45.45%112.97629,30244.4%50.0%
36.36%113.584212,627100.0%30.0%
63.64%115.31,26518,01775.0%57.1%
60.00%106.51,01615,68166.7%57.1%
55.56%96.299812,57560.0%50.0%
77.78%95.772113,47980.0%75.0%
62.50%84.069212,87733.3%80.0%
100.00%81.76568,316100.0%100.0%
25.00%81.884311,8130.0%28.6%
42.86%73.272510,9900.0%60.0%
57.14%74.392613,859100.0%40.0%
28.57%75.51,08315,464100.0%16.7%
71.43%76.91,16015,29350.0%80.0%
50.00%66.089415,5580.0%60.0%
50.00%66.971711,42050.0%50.0%
50.00%65.368811,48750.0%50.0%
50.00%66.01,26918,81950.0%50.0%
66.67%64.89788,98960.0%100.0%
33.33%66.276711,67840.0%0.0%
83.33%65.492213,98050.0%100.0%
60.00%56.094116,582100.0%50.0%
20.00%53.862311,97533.3%0.0%
60.00%56.492914,61466.7%50.0%
40.00%52.687012,1820.0%50.0%
60.00%54.86939,85133.3%100.0%
60.00%56.41,02413,67550.0%66.7%
20.00%53.25999,88650.0%0.0%
80.00%55.569312,710100.0%66.7%
60.00%52.891811,99650.0%66.7%

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Miss Fortune vs Seraphine - Frequently Asked Questions

How does Miss Fortune do against Seraphine in League of Legends?

Seraphine wins the Miss Fortune vs Seraphine matchup with a 62.5% win rate compared to Miss Fortune's 37.5%, a 25.0 percentage point difference. This data is based on 32 recent ranked games in patch 26.7.

How does Miss Fortune do against Seraphine in the early game?

In the early game, Seraphine has the advantage against Miss Fortune with a 61.5% win rate versus 38.5%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Miss Fortune do against Seraphine in the late game?

In the late game, Seraphine takes over the Miss Fortune vs Seraphine matchup with a 63.2% win rate compared to 36.8%. Seraphine scales better into team fights and objective contests after 25 minutes.

Who wins the Miss Fortune vs Seraphine matchup?

Seraphine wins the matchup against Miss Fortune with a 62.5% win rate in League of Legends patch 26.7. The 25.0 percentage point advantage means Seraphine is significantly favored in this lane matchup based on 32 games analyzed.

What is the best Miss Fortune build against Seraphine?

The best Miss Fortune build against Seraphine includes Luden's Echo, Cryptbloom, Blackfire Torch with Ionian Boots of Lucidity. Check the matchup breakdown above for the full item path and build order.

What are the best Miss Fortune runes against Seraphine?

The best Miss Fortune runes against Seraphine use the Precision primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Miss Fortune vs Seraphine matchup. See the full rune breakdown in the matchup comparison above.

Does Miss Fortune counter Seraphine?

No, Miss Fortune struggles against Seraphine with only a 37.5% win rate. Seraphine has the advantage in this matchup. Miss Fortune players should focus on safe farming and avoiding extended trades to minimize Seraphine's lead.

How do I play Miss Fortune against Seraphine?

When playing Miss Fortune against Seraphine, play cautiously and avoid Seraphine's power spikes. Look for jungle assistance and team-dependent plays since Seraphine has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.