Miss Fortune - League of Legends Champion
Win Rate
51.1%
Pick Rate
7.7%

Miss Fortunevs Seraphine

AMarksmanMage
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 4, 2026
MethodologyData Methodology

Miss Fortune vs Seraphine is a decisive matchup in LoL patch 26.11. Seraphine wins with a 61.3% win rate (+22.5%) over Miss Fortune based on 80 games. Seraphine holds the advantage in both the early and late game. Below you'll find the best Miss Fortune build, runes, laning stats, and strategies for the Miss Fortune vs Seraphine matchup.

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Miss Fortune Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Miss Fortune performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Miss Fortune - 38.8% win rate in this matchup
Miss Fortune
38.8% WR
VS
Seraphine vs Miss Fortune matchup - 61.3% win rate
Seraphine
61.3% WR

Who Wins the Miss Fortune vs Seraphine Matchup?

Seraphine wins the Miss Fortune vs Seraphine matchup
Winner
Seraphine
Matches: 80
38.8%
Win Rate
61.3%
5.6
CS / min
4.8
810
DMG / min
789
13,718
Gold / game
12,002
161
Heal / min
213
404
DMG Mitigated / min
414
0.3
CC / min
1.3
24.1%
Early Game WR
75.9%
47.1%
Late Game WR
52.9%

Miss Fortune vs Seraphine Matchup Summary

The Miss Fortune vs Seraphine matchup is a decisive matchup in League of Legends ranked play. Based on 80 recent matches analyzed, Seraphine wins with a 61.3% win rate compared to Miss Fortune's 38.8%, giving Seraphine a 22.5 percentage point advantage. Seraphine dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Miss Fortune players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Seraphine leads by 0.9s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Seraphine has a strong advantage in this matchup. Miss Fortune players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Seraphine overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Miss Fortune vs Seraphine Laning Phase Breakdown

Miss Fortune wins the laning phase against Seraphine in League of Legends

Miss Fortune is favored during the laning phase against Seraphine, winning 3 out of 5 key stat categories. Miss Fortune holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
5.6Miss Fortune
4.8Seraphine
Miss Fortune edges out Seraphine by 0.8 CS per minute — a moderate farming advantage that adds up to roughly 12 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Miss Fortune.
Damage
810Miss Fortune
789Seraphine
Damage output is virtually even between Miss Fortune and Seraphine, with only 20 DMG/min separating them. Fights in this matchup are decided more by ability timing and positioning than raw damage numbers, making mechanical skill the deciding factor in trades.
Economy
13,718Miss Fortune
12,002Seraphine
Miss Fortune generates a commanding 1,716 more gold per game than Seraphine. This substantial economic advantage means Miss Fortune consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Seraphine should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.3Miss Fortune
1.3Seraphine
Seraphine brings significantly more crowd control than Miss Fortune, with 0.9 more seconds of CC per minute. This large utility gap makes Seraphine far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Miss Fortune should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
566Miss Fortune
627Seraphine
Seraphine heals and mitigates 62 more damage per minute than Miss Fortune, providing moderate extra durability. This sustain edge allows Seraphine to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Miss Fortune.

Best Miss Fortune Build Against Seraphine

Ionian Boots of Lucidity is the optimal boots choice against Seraphine, providing the mobility and stats Miss Fortune needs most in this matchup. The top-performing core items for Miss Fortune against Seraphine are Luden's Echo, Liandry's Torment and Blackfire Torch. This combination gives Miss Fortune an effective balance of damage, survivability, and utility for the matchup. This build achieves a solid 50.0% win rate across 2 games, proving it to be a reliable item path when facing Seraphine. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Miss Fortune vs Seraphine matchup.

Early Game vs Late Game

Early Game
Seraphine
75.9%
+51.7% advantage
Miss Fortune early game win rateMiss Fortune24.1%
Seraphine early game win rateSeraphine75.9%
Late Game
Seraphine
52.9%
+5.9% advantage
Miss Fortune late game win rateMiss Fortune47.1%
Seraphine late game win rateSeraphine52.9%

Seraphine dominates the early game (first 15 minutes) with a commanding 75.9% win rate — a 51.7 percentage point lead over Miss Fortune. This lopsided early game means Seraphine can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Seraphine is far superior in the late game (25+ minutes), boasting a 52.9% win rate — 5.9 points above Miss Fortune. Extended games heavily favor Seraphine, whose kit and scaling make them a dominant force in team fights and objective control.

Seraphine holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Miss Fortune players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Miss Fortune Runes Against Seraphine

Inspiration rune tree - Miss Fortune primary runes vs SeraphineInspiration
First Strike - best Miss Fortune rune vs SeraphineCash Back - best Miss Fortune rune vs SeraphineBiscuit Delivery - best Miss Fortune rune vs SeraphineCosmic Insight - best Miss Fortune rune vs Seraphine
Sorcery rune tree - Miss Fortune secondary runes vs SeraphineSorcery
Gathering Storm - best Miss Fortune rune vs SeraphineManaflow Band - best Miss Fortune rune vs Seraphine
45.5% WR

The Inspiration and Sorcery rune setup gives Miss Fortune the best tools to compete against Seraphine in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Miss Fortune matchup data for League of Legends patch 26.11. The table below shows Miss Fortune's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Miss Fortune build, runes, laning stats, and early vs late game analysis for that specific matchup.

Miss Fortune matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
50.82%1,4096.383313,77450.7%50.9%
48.54%1,0306.386714,23847.8%49.1%
51.88%9066.489413,99951.2%52.4%
51.50%9016.283413,96744.7%56.2%
48.38%8006.590114,44549.9%47.4%
54.66%5366.589114,04752.9%56.0%
54.77%4516.489214,21850.0%58.0%
53.74%4286.393314,42655.1%52.7%
49.52%4166.184013,73544.6%53.5%
53.55%3666.288813,79754.0%53.0%
54.34%3466.083513,93257.7%51.8%
58.49%3186.587014,14358.1%58.8%
56.23%2656.384314,13150.9%60.0%
53.88%2456.184614,02952.2%55.4%
56.22%2336.486914,37158.3%54.7%
45.22%2306.488614,02846.7%43.9%
47.53%2236.287114,29441.3%51.0%
51.98%1776.385513,75856.9%48.6%
52.57%1756.487115,03847.4%55.1%
52.53%1586.590914,31756.7%49.5%
53.57%1406.790714,28149.1%56.8%
50.78%1286.391814,56241.4%58.6%
45.97%1246.279513,00533.3%55.7%
53.21%1096.585913,21049.1%57.7%
48.24%855.778413,46347.4%48.9%
38.75%805.681013,71824.1%47.1%
49.37%796.492114,08946.9%51.1%
47.44%785.482313,50637.5%51.9%
42.86%776.486814,87734.8%46.3%
38.16%766.282714,09737.1%39.0%
45.21%736.286713,88537.9%50.0%
65.22%696.698914,91462.9%67.7%
54.00%505.975613,38252.0%56.0%
39.39%335.676012,10150.0%29.4%
46.67%305.877513,27238.5%52.9%
44.83%296.593014,65833.3%57.1%
39.13%236.51,04814,0279.1%66.7%
45.45%226.587814,88033.3%53.9%
33.33%216.871812,11442.9%14.3%
50.00%206.71,08516,04216.7%64.3%
57.89%193.875313,77260.0%57.1%
38.89%184.868813,07940.0%38.5%
55.56%186.698914,62677.8%33.3%
47.06%176.067014,25640.0%50.0%
43.75%165.596712,91862.5%25.0%
20.00%156.280414,17716.7%22.2%
38.46%133.068511,02420.0%50.0%
46.15%132.376411,348100.0%41.7%
41.67%126.197013,34220.0%57.1%
54.55%113.376612,22850.0%57.1%
45.45%115.896413,89525.0%57.1%
63.64%112.571410,63975.0%57.1%
30.00%106.187313,95433.3%28.6%
50.00%105.593110,28328.6%100.0%
44.44%92.671310,58350.0%40.0%
55.56%95.367813,11550.0%60.0%
66.67%95.594414,726100.0%62.5%
62.50%85.898214,20780.0%33.3%
37.50%82.07588,70875.0%0.0%
50.00%86.174013,31440.0%66.7%
75.00%84.286914,23975.0%75.0%
75.00%85.588613,88566.7%80.0%
75.00%84.878412,52566.7%80.0%
75.00%86.181914,565100.0%50.0%
42.86%71.94717,58440.0%50.0%
57.14%75.783814,884100.0%25.0%
14.29%75.064010,96725.0%0.0%
71.43%75.51,20914,4610.0%100.0%
42.86%75.21,10313,23040.0%50.0%
42.86%76.884913,70433.3%50.0%
42.86%72.77849,58625.0%66.7%
57.14%73.498713,24850.0%66.7%
71.43%73.988813,26775.0%66.7%
33.33%66.870313,25233.3%33.3%
50.00%65.66189,63960.0%0.0%
66.67%66.31,25919,5000.0%80.0%
33.33%65.71,17515,44650.0%25.0%
20.00%55.571311,92633.3%0.0%
40.00%56.265110,14650.0%33.3%
60.00%53.079710,43550.0%66.7%
40.00%55.079211,2730.0%66.7%
80.00%56.81,07916,1040.0%100.0%
40.00%53.064510,75850.0%33.3%
20.00%52.76057,73750.0%0.0%
20.00%55.488513,37933.3%0.0%
40.00%52.15848,74433.3%50.0%
40.00%57.097313,4030.0%66.7%
80.00%55.71,17116,0300.0%80.0%
40.00%55.01,22815,65750.0%33.3%
60.00%55.81,27022,3880.0%100.0%
80.00%52.88938,878100.0%50.0%

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Miss Fortune vs Seraphine - Frequently Asked Questions

How does Miss Fortune do against Seraphine in League of Legends?

Seraphine wins the Miss Fortune vs Seraphine matchup with a 61.3% win rate compared to Miss Fortune's 38.8%, a 22.5 percentage point difference. This data is based on 80 recent ranked games in patch 26.11.

How does Miss Fortune do against Seraphine in the early game?

In the early game, Seraphine has the advantage against Miss Fortune with a 75.9% win rate versus 24.1%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Miss Fortune do against Seraphine in the late game?

In the late game, Seraphine takes over the Miss Fortune vs Seraphine matchup with a 52.9% win rate compared to 47.1%. Seraphine scales better into team fights and objective contests after 25 minutes.

Who wins the Miss Fortune vs Seraphine matchup?

Seraphine wins the matchup against Miss Fortune with a 61.3% win rate in League of Legends patch 26.11. The 22.5 percentage point advantage means Seraphine is significantly favored in this lane matchup based on 80 games analyzed.

What is the best Miss Fortune build against Seraphine?

The best Miss Fortune build against Seraphine includes Luden's Echo, Liandry's Torment, Blackfire Torch with Ionian Boots of Lucidity. This build achieves a 50.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Miss Fortune runes against Seraphine?

The best Miss Fortune runes against Seraphine use the Inspiration primary tree with Sorcery secondary. This rune setup achieves a 45.5% win rate in the Miss Fortune vs Seraphine matchup. See the full rune breakdown in the matchup comparison above.

Does Miss Fortune counter Seraphine?

No, Miss Fortune struggles against Seraphine with only a 38.8% win rate. Seraphine has the advantage in this matchup. Miss Fortune players should focus on safe farming and avoiding extended trades to minimize Seraphine's lead.

How do I play Miss Fortune against Seraphine?

When playing Miss Fortune against Seraphine, play cautiously and avoid Seraphine's power spikes. Look for jungle assistance and team-dependent plays since Seraphine has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.