Miss Fortunevs Vayne
Miss Fortune vs Vayne is a decisive matchup in LoL patch 26.11. Miss Fortune wins with a 53.7% win rate (+7.5%) over Vayne based on 428 games. Miss Fortune holds the advantage in both the early and late game. Below you'll find the best Miss Fortune build, runes, laning stats, and strategies for the Miss Fortune vs Vayne matchup.
Miss Fortune Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Miss Fortune performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Miss Fortune vs Vayne Matchup?
Miss Fortune vs Vayne Matchup Summary
The Miss Fortune vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 428 recent matches analyzed, Miss Fortune wins with a 53.7% win rate compared to Vayne's 46.3%, giving Miss Fortune a 7.5 percentage point advantage. Miss Fortune dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Vayne players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Vayne leads by 0.1s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Miss Fortune players can confidently pick into Vayne and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Vayne away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Miss Fortune vs Vayne Laning Phase Breakdown
Miss Fortune is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Miss Fortune holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.
Early Game vs Late Game
Miss Fortune55.1%
Vayne44.9%Miss Fortune52.7%Vayne47.3%Miss Fortune dominates the early game (first 15 minutes) with a commanding 55.1% win rate — a 10.2 percentage point lead over Vayne. This lopsided early game means Miss Fortune can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Miss Fortune is far superior in the late game (25+ minutes), boasting a 52.7% win rate — 5.4 points above Vayne. Extended games heavily favor Miss Fortune, whose kit and scaling make them a dominant force in team fights and objective control.
Miss Fortune holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Vayne players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Miss Fortune Runes Against Vayne
Precision
Inspiration
Running Precision primary with Inspiration secondary allows Miss Fortune to press their advantage against Vayne, amplifying the strengths that make this a favorable matchup.
Miss Fortune matchup data for League of Legends patch 26.11. The table below shows Miss Fortune's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Miss Fortune build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 50.82% | 1,409 | 6.3 | 833 | 13,774 | 50.7% | 50.9% | |
| 48.54% | 1,030 | 6.3 | 867 | 14,238 | 47.8% | 49.1% | |
| 51.88% | 906 | 6.4 | 894 | 13,999 | 51.2% | 52.4% | |
| 51.50% | 901 | 6.2 | 834 | 13,967 | 44.7% | 56.2% | |
| 48.38% | 800 | 6.5 | 901 | 14,445 | 49.9% | 47.4% | |
| 54.66% | 536 | 6.5 | 891 | 14,047 | 52.9% | 56.0% | |
| 54.77% | 451 | 6.4 | 892 | 14,218 | 50.0% | 58.0% | |
| 53.74% | 428 | 6.3 | 933 | 14,426 | 55.1% | 52.7% | |
| 49.52% | 416 | 6.1 | 840 | 13,735 | 44.6% | 53.5% | |
| 53.55% | 366 | 6.2 | 888 | 13,797 | 54.0% | 53.0% | |
| 54.34% | 346 | 6.0 | 835 | 13,932 | 57.7% | 51.8% | |
| 58.49% | 318 | 6.5 | 870 | 14,143 | 58.1% | 58.8% | |
| 56.23% | 265 | 6.3 | 843 | 14,131 | 50.9% | 60.0% | |
| 53.88% | 245 | 6.1 | 846 | 14,029 | 52.2% | 55.4% | |
| 56.22% | 233 | 6.4 | 869 | 14,371 | 58.3% | 54.7% | |
| 45.22% | 230 | 6.4 | 886 | 14,028 | 46.7% | 43.9% | |
| 47.53% | 223 | 6.2 | 871 | 14,294 | 41.3% | 51.0% | |
| 51.98% | 177 | 6.3 | 855 | 13,758 | 56.9% | 48.6% | |
| 52.57% | 175 | 6.4 | 871 | 15,038 | 47.4% | 55.1% | |
| 52.53% | 158 | 6.5 | 909 | 14,317 | 56.7% | 49.5% | |
| 53.57% | 140 | 6.7 | 907 | 14,281 | 49.1% | 56.8% | |
| 50.78% | 128 | 6.3 | 918 | 14,562 | 41.4% | 58.6% | |
| 45.97% | 124 | 6.2 | 795 | 13,005 | 33.3% | 55.7% | |
| 53.21% | 109 | 6.5 | 859 | 13,210 | 49.1% | 57.7% | |
| 48.24% | 85 | 5.7 | 784 | 13,463 | 47.4% | 48.9% | |
| 38.75% | 80 | 5.6 | 810 | 13,718 | 24.1% | 47.1% | |
| 49.37% | 79 | 6.4 | 921 | 14,089 | 46.9% | 51.1% | |
| 47.44% | 78 | 5.4 | 823 | 13,506 | 37.5% | 51.9% | |
| 42.86% | 77 | 6.4 | 868 | 14,877 | 34.8% | 46.3% | |
| 38.16% | 76 | 6.2 | 827 | 14,097 | 37.1% | 39.0% | |
| 45.21% | 73 | 6.2 | 867 | 13,885 | 37.9% | 50.0% | |
| 65.22% | 69 | 6.6 | 989 | 14,914 | 62.9% | 67.7% | |
| 54.00% | 50 | 5.9 | 756 | 13,382 | 52.0% | 56.0% | |
| 39.39% | 33 | 5.6 | 760 | 12,101 | 50.0% | 29.4% | |
| 46.67% | 30 | 5.8 | 775 | 13,272 | 38.5% | 52.9% | |
| 44.83% | 29 | 6.5 | 930 | 14,658 | 33.3% | 57.1% | |
| 39.13% | 23 | 6.5 | 1,048 | 14,027 | 9.1% | 66.7% | |
| 45.45% | 22 | 6.5 | 878 | 14,880 | 33.3% | 53.9% | |
| 33.33% | 21 | 6.8 | 718 | 12,114 | 42.9% | 14.3% | |
| 50.00% | 20 | 6.7 | 1,085 | 16,042 | 16.7% | 64.3% | |
| 57.89% | 19 | 3.8 | 753 | 13,772 | 60.0% | 57.1% | |
| 38.89% | 18 | 4.8 | 688 | 13,079 | 40.0% | 38.5% | |
| 55.56% | 18 | 6.6 | 989 | 14,626 | 77.8% | 33.3% | |
| 47.06% | 17 | 6.0 | 670 | 14,256 | 40.0% | 50.0% | |
| 43.75% | 16 | 5.5 | 967 | 12,918 | 62.5% | 25.0% | |
| 20.00% | 15 | 6.2 | 804 | 14,177 | 16.7% | 22.2% | |
| 38.46% | 13 | 3.0 | 685 | 11,024 | 20.0% | 50.0% | |
| 46.15% | 13 | 2.3 | 764 | 11,348 | 100.0% | 41.7% | |
| 41.67% | 12 | 6.1 | 970 | 13,342 | 20.0% | 57.1% | |
| 54.55% | 11 | 3.3 | 766 | 12,228 | 50.0% | 57.1% | |
| 45.45% | 11 | 5.8 | 964 | 13,895 | 25.0% | 57.1% | |
| 63.64% | 11 | 2.5 | 714 | 10,639 | 75.0% | 57.1% | |
| 30.00% | 10 | 6.1 | 873 | 13,954 | 33.3% | 28.6% | |
| 50.00% | 10 | 5.5 | 931 | 10,283 | 28.6% | 100.0% | |
| 44.44% | 9 | 2.6 | 713 | 10,583 | 50.0% | 40.0% | |
| 55.56% | 9 | 5.3 | 678 | 13,115 | 50.0% | 60.0% | |
| 66.67% | 9 | 5.5 | 944 | 14,726 | 100.0% | 62.5% | |
| 62.50% | 8 | 5.8 | 982 | 14,207 | 80.0% | 33.3% | |
| 37.50% | 8 | 2.0 | 758 | 8,708 | 75.0% | 0.0% | |
| 50.00% | 8 | 6.1 | 740 | 13,314 | 40.0% | 66.7% | |
| 75.00% | 8 | 4.2 | 869 | 14,239 | 75.0% | 75.0% | |
| 75.00% | 8 | 5.5 | 886 | 13,885 | 66.7% | 80.0% | |
| 75.00% | 8 | 4.8 | 784 | 12,525 | 66.7% | 80.0% | |
| 75.00% | 8 | 6.1 | 819 | 14,565 | 100.0% | 50.0% | |
| 42.86% | 7 | 1.9 | 471 | 7,584 | 40.0% | 50.0% | |
| 57.14% | 7 | 5.7 | 838 | 14,884 | 100.0% | 25.0% | |
| 14.29% | 7 | 5.0 | 640 | 10,967 | 25.0% | 0.0% | |
| 71.43% | 7 | 5.5 | 1,209 | 14,461 | 0.0% | 100.0% | |
| 42.86% | 7 | 5.2 | 1,103 | 13,230 | 40.0% | 50.0% | |
| 42.86% | 7 | 6.8 | 849 | 13,704 | 33.3% | 50.0% | |
| 42.86% | 7 | 2.7 | 784 | 9,586 | 25.0% | 66.7% | |
| 57.14% | 7 | 3.4 | 987 | 13,248 | 50.0% | 66.7% | |
| 71.43% | 7 | 3.9 | 888 | 13,267 | 75.0% | 66.7% | |
| 33.33% | 6 | 6.8 | 703 | 13,252 | 33.3% | 33.3% | |
| 50.00% | 6 | 5.6 | 618 | 9,639 | 60.0% | 0.0% | |
| 66.67% | 6 | 6.3 | 1,259 | 19,500 | 0.0% | 80.0% | |
| 33.33% | 6 | 5.7 | 1,175 | 15,446 | 50.0% | 25.0% | |
| 20.00% | 5 | 5.5 | 713 | 11,926 | 33.3% | 0.0% | |
| 40.00% | 5 | 6.2 | 651 | 10,146 | 50.0% | 33.3% | |
| 60.00% | 5 | 3.0 | 797 | 10,435 | 50.0% | 66.7% | |
| 40.00% | 5 | 5.0 | 792 | 11,273 | 0.0% | 66.7% | |
| 80.00% | 5 | 6.8 | 1,079 | 16,104 | 0.0% | 100.0% | |
| 40.00% | 5 | 3.0 | 645 | 10,758 | 50.0% | 33.3% | |
| 20.00% | 5 | 2.7 | 605 | 7,737 | 50.0% | 0.0% | |
| 20.00% | 5 | 5.4 | 885 | 13,379 | 33.3% | 0.0% | |
| 40.00% | 5 | 2.1 | 584 | 8,744 | 33.3% | 50.0% | |
| 40.00% | 5 | 7.0 | 973 | 13,403 | 0.0% | 66.7% | |
| 80.00% | 5 | 5.7 | 1,171 | 16,030 | 0.0% | 80.0% | |
| 40.00% | 5 | 5.0 | 1,228 | 15,657 | 50.0% | 33.3% | |
| 60.00% | 5 | 5.8 | 1,270 | 22,388 | 0.0% | 100.0% | |
| 80.00% | 5 | 2.8 | 893 | 8,878 | 100.0% | 50.0% | |
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Miss Fortune vs Vayne - Frequently Asked Questions
How does Miss Fortune do against Vayne in League of Legends?
Miss Fortune wins the Miss Fortune vs Vayne matchup with a 53.7% win rate compared to Vayne's 46.3%, a 7.5 percentage point difference. This data is based on 428 recent ranked games in patch 26.11.
How does Miss Fortune do against Vayne in the early game?
In the early game, Miss Fortune has the advantage against Vayne with a 55.1% win rate versus 44.9%. Miss Fortune players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Miss Fortune do against Vayne in the late game?
In the late game, Miss Fortune takes over the Miss Fortune vs Vayne matchup with a 52.7% win rate compared to 47.3%. Miss Fortune scales better into team fights and objective contests after 25 minutes.
Who wins the Miss Fortune vs Vayne matchup?
Miss Fortune wins the matchup against Vayne with a 53.7% win rate in League of Legends patch 26.11. The 7.5 percentage point advantage means Miss Fortune is significantly favored in this lane matchup based on 428 games analyzed.
What is the best Miss Fortune build against Vayne?
The best Miss Fortune build against Vayne includes optimized core items. Check the matchup breakdown above for the full item path and build order.
What are the best Miss Fortune runes against Vayne?
The best Miss Fortune runes against Vayne use the Precision primary tree with Inspiration secondary. This rune setup achieves a 54.5% win rate in the Miss Fortune vs Vayne matchup. See the full rune breakdown in the matchup comparison above.
Does Miss Fortune counter Vayne?
Yes, Miss Fortune has a favorable matchup against Vayne with a 53.7% win rate. Miss Fortune strongly counters Vayne in lane based on current patch 26.11 data.
How do I play Miss Fortune against Vayne?
When playing Miss Fortune against Vayne, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.