Miss Fortunevs Vayne
Miss Fortune vs Vayne is a very close matchup in LoL patch 26.7. Miss Fortune wins with a 51.0% win rate (+2.0%) over Vayne based on 302 games. Miss Fortune wins the early laning phase while Vayne scales better into the late game. Below you'll find the best Miss Fortune build, runes, laning stats, and strategies for the Miss Fortune vs Vayne matchup.
Miss Fortune Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Miss Fortune performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Vayne(51.0%)Who Wins the Miss Fortune vs Vayne Matchup?
Miss Fortune vs Vayne Matchup Summary
The Miss Fortune vs Vayne matchup is a very close matchup in League of Legends ranked play. Based on 302 recent matches analyzed, Miss Fortune wins with a 51.0% win rate compared to Vayne's 49.0%, giving Miss Fortune a 2.0 percentage point advantage. Game phase dynamics play a critical role here: Miss Fortune controls the early laning stage, but Vayne outscales as the game goes longer. The matchup shifts dramatically depending on game length — Miss Fortune needs to press advantages before Vayne reaches their power spikes, while Vayne should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Vayne leads by 0.1s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Miss Fortune has a statistical edge, but the margin is close enough that respecting Vayne's strengths is important. Trade when cooldowns are favorable, track the enemy jungler, and build toward your strongest item spikes to convert the slight advantage into a decisive lead. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Miss Fortune vs Vayne Laning Phase Breakdown
Miss Fortune is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Miss Fortune holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.
Early Game vs Late Game
Miss Fortune52.5%Vayne47.5%Miss Fortune49.7%Vayne50.3%Miss Fortune dominates the early game (first 15 minutes) with a commanding 52.5% win rate — a 5.0 percentage point lead over Vayne. This lopsided early game means Miss Fortune can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Late game (25+ minutes) is equally balanced, with Vayne at 50.3% win rate — only 0.6 points ahead of Miss Fortune. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.
The power dynamics shift as the game progresses — Miss Fortune has the edge early, but Vayne gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.
Best Miss Fortune Runes Against Vayne
Precision
Inspiration
The Precision primary with Inspiration secondary combination helps Miss Fortune maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Vayne.
Miss Fortune matchup data for League of Legends patch 26.7. The table below shows Miss Fortune's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Miss Fortune build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 51.18% | 932 | 6.4 | 863 | 14,622 | 51.4% | 51.0% | |
| 47.82% | 688 | 6.4 | 857 | 14,112 | 46.4% | 49.0% | |
| 51.53% | 654 | 6.4 | 916 | 14,838 | 50.5% | 52.2% | |
| 51.90% | 632 | 6.3 | 863 | 14,645 | 51.6% | 52.1% | |
| 47.56% | 450 | 6.5 | 903 | 15,036 | 43.8% | 49.7% | |
| 54.96% | 393 | 6.5 | 923 | 14,755 | 48.5% | 59.8% | |
| 50.44% | 341 | 6.4 | 909 | 14,206 | 46.1% | 54.6% | |
| 50.99% | 302 | 6.5 | 907 | 14,430 | 52.5% | 49.7% | |
| 46.77% | 263 | 6.6 | 883 | 14,881 | 53.6% | 41.7% | |
| 54.44% | 248 | 6.4 | 878 | 14,273 | 54.3% | 54.5% | |
| 45.15% | 237 | 6.2 | 837 | 14,330 | 48.5% | 42.6% | |
| 48.80% | 209 | 6.2 | 872 | 14,612 | 45.1% | 52.3% | |
| 55.14% | 185 | 6.4 | 862 | 14,229 | 60.0% | 51.0% | |
| 53.85% | 182 | 6.2 | 852 | 13,849 | 52.8% | 55.0% | |
| 52.07% | 169 | 6.6 | 873 | 15,108 | 55.4% | 50.0% | |
| 59.01% | 161 | 6.4 | 882 | 14,095 | 56.6% | 61.2% | |
| 48.67% | 150 | 6.5 | 902 | 14,831 | 48.3% | 48.9% | |
| 49.62% | 133 | 6.1 | 863 | 13,608 | 47.0% | 52.2% | |
| 49.12% | 114 | 6.3 | 905 | 13,917 | 46.4% | 51.7% | |
| 50.55% | 91 | 6.7 | 901 | 14,263 | 45.5% | 55.3% | |
| 42.70% | 89 | 6.4 | 842 | 12,905 | 40.9% | 44.4% | |
| 44.71% | 85 | 6.2 | 921 | 15,073 | 46.9% | 43.4% | |
| 63.10% | 84 | 6.6 | 988 | 16,027 | 68.4% | 58.7% | |
| 52.56% | 78 | 6.2 | 720 | 14,008 | 54.8% | 51.1% | |
| 62.16% | 74 | 6.1 | 1,079 | 14,577 | 58.1% | 65.1% | |
| 48.57% | 70 | 6.4 | 954 | 15,380 | 61.5% | 40.9% | |
| 44.93% | 69 | 6.3 | 791 | 14,059 | 35.5% | 52.6% | |
| 56.06% | 66 | 6.1 | 854 | 14,056 | 65.5% | 48.6% | |
| 57.69% | 52 | 6.4 | 843 | 15,493 | 55.6% | 58.8% | |
| 50.00% | 50 | 5.7 | 668 | 11,637 | 48.1% | 52.2% | |
| 58.97% | 39 | 6.5 | 981 | 15,646 | 53.3% | 62.5% | |
| 54.29% | 35 | 6.6 | 991 | 14,900 | 53.3% | 55.0% | |
| 37.50% | 32 | 5.2 | 867 | 13,525 | 38.5% | 36.8% | |
| 56.00% | 25 | 5.5 | 830 | 11,702 | 57.1% | 54.5% | |
| 36.36% | 22 | 6.3 | 891 | 15,998 | 37.5% | 35.7% | |
| 52.63% | 19 | 6.4 | 911 | 16,542 | 33.3% | 70.0% | |
| 66.67% | 18 | 4.0 | 905 | 12,829 | 54.5% | 85.7% | |
| 58.82% | 17 | 5.8 | 820 | 13,412 | 57.1% | 60.0% | |
| 64.71% | 17 | 6.7 | 943 | 12,688 | 54.5% | 83.3% | |
| 31.25% | 16 | 6.2 | 811 | 13,906 | 37.5% | 25.0% | |
| 23.08% | 13 | 2.4 | 844 | 11,293 | 25.0% | 22.2% | |
| 38.46% | 13 | 6.3 | 627 | 9,501 | 30.0% | 66.7% | |
| 61.54% | 13 | 6.7 | 912 | 12,678 | 60.0% | 66.7% | |
| 46.15% | 13 | 6.7 | 910 | 13,364 | 50.0% | 44.4% | |
| 50.00% | 12 | 4.8 | 987 | 11,970 | 83.3% | 16.7% | |
| 45.45% | 11 | 2.9 | 762 | 9,302 | 44.4% | 50.0% | |
| 36.36% | 11 | 3.5 | 842 | 12,627 | 100.0% | 30.0% | |
| 63.64% | 11 | 5.3 | 1,265 | 18,017 | 75.0% | 57.1% | |
| 60.00% | 10 | 6.5 | 1,016 | 15,681 | 66.7% | 57.1% | |
| 55.56% | 9 | 6.2 | 998 | 12,575 | 60.0% | 50.0% | |
| 77.78% | 9 | 5.7 | 721 | 13,479 | 80.0% | 75.0% | |
| 62.50% | 8 | 4.0 | 692 | 12,877 | 33.3% | 80.0% | |
| 100.00% | 8 | 1.7 | 656 | 8,316 | 100.0% | 100.0% | |
| 25.00% | 8 | 1.8 | 843 | 11,813 | 0.0% | 28.6% | |
| 42.86% | 7 | 3.2 | 725 | 10,990 | 0.0% | 60.0% | |
| 57.14% | 7 | 4.3 | 926 | 13,859 | 100.0% | 40.0% | |
| 28.57% | 7 | 5.5 | 1,083 | 15,464 | 100.0% | 16.7% | |
| 71.43% | 7 | 6.9 | 1,160 | 15,293 | 50.0% | 80.0% | |
| 50.00% | 6 | 6.0 | 894 | 15,558 | 0.0% | 60.0% | |
| 50.00% | 6 | 6.9 | 717 | 11,420 | 50.0% | 50.0% | |
| 50.00% | 6 | 5.3 | 688 | 11,487 | 50.0% | 50.0% | |
| 50.00% | 6 | 6.0 | 1,269 | 18,819 | 50.0% | 50.0% | |
| 66.67% | 6 | 4.8 | 978 | 8,989 | 60.0% | 100.0% | |
| 33.33% | 6 | 6.2 | 767 | 11,678 | 40.0% | 0.0% | |
| 83.33% | 6 | 5.4 | 922 | 13,980 | 50.0% | 100.0% | |
| 60.00% | 5 | 6.0 | 941 | 16,582 | 100.0% | 50.0% | |
| 20.00% | 5 | 3.8 | 623 | 11,975 | 33.3% | 0.0% | |
| 60.00% | 5 | 6.4 | 929 | 14,614 | 66.7% | 50.0% | |
| 40.00% | 5 | 2.6 | 870 | 12,182 | 0.0% | 50.0% | |
| 60.00% | 5 | 4.8 | 693 | 9,851 | 33.3% | 100.0% | |
| 60.00% | 5 | 6.4 | 1,024 | 13,675 | 50.0% | 66.7% | |
| 20.00% | 5 | 3.2 | 599 | 9,886 | 50.0% | 0.0% | |
| 80.00% | 5 | 5.5 | 693 | 12,710 | 100.0% | 66.7% | |
| 60.00% | 5 | 2.8 | 918 | 11,996 | 50.0% | 66.7% | |
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Miss Fortune vs Vayne - Frequently Asked Questions
How does Miss Fortune do against Vayne in League of Legends?
Miss Fortune wins the Miss Fortune vs Vayne matchup with a 51.0% win rate compared to Vayne's 49.0%, a 2.0 percentage point difference. This data is based on 302 recent ranked games in patch 26.7.
How does Miss Fortune do against Vayne in the early game?
In the early game, Miss Fortune has the advantage against Vayne with a 52.5% win rate versus 47.5%. Miss Fortune players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Miss Fortune do against Vayne in the late game?
In the late game, Vayne takes over the Miss Fortune vs Vayne matchup with a 50.3% win rate compared to 49.7%. Vayne scales better into team fights and objective contests after 25 minutes.
Who wins the Miss Fortune vs Vayne matchup?
Miss Fortune wins the matchup against Vayne with a 51.0% win rate in League of Legends patch 26.7. The 2.0 percentage point advantage means Miss Fortune is slightly favored in this lane matchup based on 302 games analyzed.
What is the best Miss Fortune build against Vayne?
The best Miss Fortune build against Vayne includes optimized core items. Check the matchup breakdown above for the full item path and build order.
What are the best Miss Fortune runes against Vayne?
The best Miss Fortune runes against Vayne use the Precision primary tree with Inspiration secondary. This rune setup achieves a 57.6% win rate in the Miss Fortune vs Vayne matchup. See the full rune breakdown in the matchup comparison above.
Does Miss Fortune counter Vayne?
Yes, Miss Fortune has a favorable matchup against Vayne with a 51.0% win rate. Miss Fortune slightly edges out Vayne in lane based on current patch 26.7 data.
How do I play Miss Fortune against Vayne?
When playing Miss Fortune against Vayne, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.