Miss Fortunevs Karthus
Miss Fortune vs Karthus is a decisive matchup in LoL patch 26.4. Karthus wins with a 63.2% win rate (+26.3%) over Miss Fortune based on 21 games. Karthus holds the advantage in both the early and late game. Below you'll find the best Miss Fortune build, runes, laning stats, and strategies for the Miss Fortune vs Karthus matchup.
Miss Fortune Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Miss Fortune performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Karthus(36.8%)Who Wins the Miss Fortune vs Karthus Matchup?
Miss Fortune vs Karthus Matchup Summary
The Miss Fortune vs Karthus matchup is a decisive matchup in League of Legends ranked play. Based on 21 recent matches analyzed, Karthus wins with a 63.2% win rate compared to Miss Fortune's 36.8%, giving Karthus a 26.3 percentage point advantage. Karthus dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Miss Fortune players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Karthus leads by 0.3s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Karthus has a strong advantage in this matchup. Miss Fortune players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Karthus overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Miss Fortune vs Karthus Laning Phase Breakdown
Miss Fortune is favored during the laning phase against Karthus, winning 3 out of 5 key stat categories. Miss Fortune holds advantages in farming, gold income and sustain, making them the stronger laner in this matchup.
Early Game vs Late Game
Miss Fortune44.4%Karthus55.6%Miss Fortune30.0%Karthus70.0%Karthus dominates the early game (first 15 minutes) with a commanding 55.6% win rate — a 11.1 percentage point lead over Miss Fortune. This lopsided early game means Karthus can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Karthus is far superior in the late game (25+ minutes), boasting a 70.0% win rate — 40.0 points above Miss Fortune. Extended games heavily favor Karthus, whose kit and scaling make them a dominant force in team fights and objective control.
Karthus holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Miss Fortune players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Miss Fortune Runes Against Karthus
Inspiration
Sorcery
The Inspiration and Sorcery rune setup gives Miss Fortune the best tools to compete against Karthus in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Miss Fortune matchup data for League of Legends patch 26.4. The table below shows Miss Fortune's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Miss Fortune build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 52.18% | 2,105 | 6.5 | 868 | 14,482 | 51.0% | 53.1% | |
| 49.25% | 1,466 | 6.5 | 900 | 14,429 | 53.6% | 45.3% | |
| 53.25% | 1,267 | 6.4 | 872 | 14,491 | 51.0% | 54.9% | |
| 49.85% | 1,035 | 6.2 | 870 | 14,649 | 46.9% | 52.0% | |
| 53.33% | 816 | 6.7 | 951 | 15,157 | 54.5% | 52.4% | |
| 49.75% | 795 | 6.7 | 924 | 15,418 | 50.3% | 49.4% | |
| 54.00% | 790 | 6.6 | 903 | 14,529 | 46.8% | 60.1% | |
| 49.53% | 643 | 6.5 | 936 | 15,201 | 48.2% | 50.5% | |
| 50.25% | 597 | 6.3 | 919 | 14,296 | 47.7% | 52.6% | |
| 47.17% | 587 | 6.1 | 842 | 14,408 | 48.8% | 46.0% | |
| 55.43% | 526 | 6.3 | 897 | 14,633 | 57.1% | 54.2% | |
| 52.57% | 489 | 6.6 | 876 | 14,486 | 51.8% | 53.2% | |
| 54.45% | 484 | 6.8 | 865 | 14,793 | 53.5% | 55.2% | |
| 54.44% | 420 | 6.8 | 941 | 14,977 | 60.7% | 48.3% | |
| 51.23% | 408 | 6.6 | 917 | 14,982 | 51.7% | 50.9% | |
| 53.09% | 408 | 6.5 | 902 | 14,505 | 56.8% | 50.0% | |
| 50.42% | 356 | 6.4 | 875 | 14,482 | 47.6% | 52.9% | |
| 51.54% | 326 | 6.4 | 866 | 14,542 | 49.6% | 52.9% | |
| 43.16% | 236 | 6.4 | 869 | 14,840 | 35.6% | 47.6% | |
| 52.04% | 222 | 6.7 | 878 | 14,941 | 52.9% | 51.3% | |
| 46.58% | 219 | 6.2 | 988 | 14,058 | 39.4% | 52.0% | |
| 45.59% | 205 | 6.7 | 915 | 14,467 | 44.3% | 46.5% | |
| 40.80% | 201 | 6.3 | 873 | 14,982 | 37.8% | 42.5% | |
| 48.22% | 198 | 6.5 | 794 | 14,299 | 42.2% | 52.6% | |
| 56.45% | 187 | 6.6 | 977 | 15,007 | 60.7% | 52.9% | |
| 54.07% | 174 | 6.3 | 977 | 15,516 | 52.9% | 54.9% | |
| 45.56% | 170 | 6.6 | 956 | 14,486 | 45.5% | 45.6% | |
| 53.85% | 143 | 6.4 | 835 | 14,087 | 59.7% | 49.4% | |
| 46.55% | 117 | 5.2 | 756 | 13,764 | 25.7% | 55.6% | |
| 55.10% | 98 | 6.1 | 818 | 13,752 | 53.7% | 56.1% | |
| 44.05% | 84 | 6.4 | 948 | 14,913 | 39.3% | 46.4% | |
| 53.73% | 68 | 6.3 | 1,023 | 15,922 | 61.5% | 48.8% | |
| 39.34% | 61 | 5.9 | 800 | 13,349 | 33.3% | 44.1% | |
| 42.22% | 45 | 6.0 | 849 | 13,417 | 30.4% | 54.5% | |
| 52.38% | 42 | 6.2 | 871 | 14,296 | 38.5% | 58.6% | |
| 42.86% | 42 | 6.2 | 840 | 13,892 | 35.3% | 48.0% | |
| 48.72% | 40 | 5.6 | 865 | 14,088 | 58.8% | 40.9% | |
| 35.29% | 34 | 6.5 | 947 | 15,775 | 11.1% | 44.0% | |
| 51.72% | 30 | 6.4 | 877 | 12,680 | 69.2% | 37.5% | |
| 50.00% | 28 | 3.9 | 752 | 11,734 | 58.3% | 43.8% | |
| 38.46% | 26 | 5.5 | 912 | 11,639 | 35.7% | 41.7% | |
| 40.00% | 25 | 6.4 | 856 | 13,808 | 41.7% | 38.5% | |
| 45.83% | 24 | 4.6 | 983 | 12,192 | 50.0% | 41.7% | |
| 36.36% | 22 | 6.3 | 1,055 | 12,671 | 41.7% | 30.0% | |
| 45.45% | 22 | 1.9 | 685 | 9,565 | 50.0% | 42.9% | |
| 36.84% | 21 | 6.7 | 856 | 15,109 | 44.4% | 30.0% | |
| 40.00% | 20 | 5.9 | 741 | 13,364 | 33.3% | 45.5% | |
| 52.63% | 19 | 4.5 | 755 | 11,576 | 62.5% | 45.5% | |
| 42.11% | 19 | 2.8 | 813 | 11,312 | 40.0% | 42.9% | |
| 44.44% | 18 | 4.1 | 786 | 13,189 | 66.7% | 33.3% | |
| 66.67% | 18 | 7.0 | 1,037 | 14,937 | 77.8% | 55.6% | |
| 52.94% | 17 | 2.4 | 765 | 11,507 | 50.0% | 54.5% | |
| 64.71% | 17 | 2.8 | 805 | 11,178 | 60.0% | 66.7% | |
| 56.25% | 16 | 6.7 | 880 | 13,649 | 50.0% | 62.5% | |
| 56.25% | 16 | 6.0 | 930 | 13,795 | 50.0% | 66.7% | |
| 53.33% | 15 | 6.2 | 922 | 15,140 | 40.0% | 60.0% | |
| 57.14% | 14 | 5.4 | 914 | 14,860 | 66.7% | 54.5% | |
| 69.23% | 13 | 3.2 | 857 | 12,730 | 100.0% | 60.0% | |
| 76.92% | 13 | 7.2 | 1,063 | 17,764 | 100.0% | 72.7% | |
| 46.15% | 13 | 5.5 | 879 | 13,580 | 42.9% | 50.0% | |
| 41.67% | 12 | 5.8 | 872 | 11,239 | 28.6% | 60.0% | |
| 66.67% | 12 | 2.8 | 638 | 8,561 | 85.7% | 40.0% | |
| 66.67% | 12 | 5.8 | 913 | 13,286 | 80.0% | 57.1% | |
| 25.00% | 12 | 5.4 | 620 | 8,972 | 22.2% | 33.3% | |
| 54.55% | 11 | 5.9 | 934 | 14,594 | 50.0% | 55.6% | |
| 54.55% | 11 | 6.6 | 1,039 | 12,819 | 33.3% | 80.0% | |
| 54.55% | 11 | 5.8 | 841 | 15,174 | 40.0% | 66.7% | |
| 20.00% | 10 | 6.7 | 804 | 12,184 | 0.0% | 66.7% | |
| 30.00% | 10 | 6.1 | 677 | 11,427 | 0.0% | 60.0% | |
| 40.00% | 10 | 5.2 | 970 | 12,610 | 66.7% | 28.6% | |
| 50.00% | 10 | 2.3 | 923 | 10,497 | 66.7% | 25.0% | |
| 20.00% | 10 | 3.6 | 774 | 11,715 | 25.0% | 16.7% | |
| 55.56% | 9 | 5.8 | 662 | 11,035 | 80.0% | 25.0% | |
| 44.44% | 9 | 5.9 | 837 | 13,624 | 33.3% | 50.0% | |
| 44.44% | 9 | 2.3 | 658 | 10,741 | 0.0% | 57.1% | |
| 66.67% | 9 | 4.1 | 741 | 11,355 | 50.0% | 80.0% | |
| 77.78% | 9 | 5.6 | 842 | 15,944 | 100.0% | 75.0% | |
| 33.33% | 9 | 5.9 | 918 | 14,409 | 0.0% | 42.9% | |
| 22.22% | 9 | 5.3 | 1,007 | 15,010 | 33.3% | 16.7% | |
| 88.89% | 9 | 6.3 | 1,138 | 17,831 | 100.0% | 85.7% | |
| 100.00% | 9 | 6.1 | 959 | 14,682 | 100.0% | 100.0% | |
| 37.50% | 8 | 2.9 | 766 | 11,018 | 33.3% | 40.0% | |
| 37.50% | 8 | 2.4 | 710 | 10,468 | 100.0% | 28.6% | |
| 25.00% | 8 | 6.6 | 985 | 16,674 | 0.0% | 28.6% | |
| 87.50% | 8 | 5.8 | 907 | 11,929 | 75.0% | 100.0% | |
| 50.00% | 8 | 5.5 | 1,025 | 14,632 | 50.0% | 50.0% | |
| 62.50% | 8 | 5.9 | 849 | 12,626 | 60.0% | 66.7% | |
| 50.00% | 8 | 2.0 | 867 | 12,205 | 50.0% | 50.0% | |
| 25.00% | 8 | 6.0 | 776 | 10,725 | 25.0% | 25.0% | |
| 28.57% | 7 | 5.7 | 852 | 11,772 | 50.0% | 20.0% | |
| 14.29% | 7 | 5.9 | 892 | 15,627 | 0.0% | 16.7% | |
| 28.57% | 7 | 5.4 | 725 | 11,021 | 16.7% | 100.0% | |
| 57.14% | 7 | 6.6 | 862 | 13,741 | 0.0% | 66.7% | |
| 57.14% | 7 | 6.8 | 1,205 | 14,341 | 100.0% | 40.0% | |
| 33.33% | 6 | 5.9 | 927 | 12,987 | 33.3% | 33.3% | |
| 50.00% | 6 | 5.7 | 805 | 15,469 | 0.0% | 75.0% | |
| 50.00% | 6 | 6.9 | 1,052 | 16,690 | 50.0% | 50.0% | |
| 33.33% | 6 | 5.1 | 838 | 16,343 | 50.0% | 25.0% | |
| 33.33% | 6 | 5.7 | 739 | 10,363 | 50.0% | 0.0% | |
| 16.67% | 6 | 5.9 | 729 | 10,100 | 25.0% | 0.0% | |
| 16.67% | 6 | 6.2 | 791 | 16,247 | 0.0% | 16.7% | |
| 83.33% | 6 | 2.4 | 883 | 13,585 | 0.0% | 83.3% | |
| 66.67% | 6 | 6.6 | 865 | 15,248 | 0.0% | 80.0% | |
| 16.67% | 6 | 1.8 | 593 | 10,092 | 0.0% | 25.0% | |
| 60.00% | 5 | 3.6 | 716 | 12,326 | 33.3% | 100.0% | |
| 60.00% | 5 | 5.6 | 655 | 10,147 | 50.0% | 66.7% | |
| 20.00% | 5 | 4.1 | 1,190 | 10,870 | 0.0% | 33.3% | |
| 25.00% | 5 | 5.6 | 573 | 11,525 | 0.0% | 33.3% | |
| 40.00% | 5 | 6.7 | 769 | 10,109 | 50.0% | 0.0% | |
| 40.00% | 5 | 4.5 | 783 | 13,154 | 33.3% | 50.0% | |
| 60.00% | 5 | 3.9 | 872 | 15,127 | 50.0% | 66.7% | |
| 60.00% | 5 | 2.9 | 809 | 9,108 | 50.0% | 100.0% | |
| 80.00% | 5 | 7.1 | 979 | 12,298 | 66.7% | 100.0% | |
| 80.00% | 5 | 6.6 | 987 | 15,894 | 50.0% | 100.0% | |
| 40.00% | 5 | 7.6 | 546 | 9,041 | 50.0% | 33.3% | |
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Miss Fortune vs Karthus - Frequently Asked Questions
How does Miss Fortune do against Karthus in League of Legends?
Karthus wins the Miss Fortune vs Karthus matchup with a 63.2% win rate compared to Miss Fortune's 36.8%, a 26.3 percentage point difference. This data is based on 21 recent ranked games in patch 26.4.
How does Miss Fortune do against Karthus in the early game?
In the early game, Karthus has the advantage against Miss Fortune with a 55.6% win rate versus 44.4%. Karthus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Miss Fortune do against Karthus in the late game?
In the late game, Karthus takes over the Miss Fortune vs Karthus matchup with a 70.0% win rate compared to 30.0%. Karthus scales better into team fights and objective contests after 25 minutes.
Who wins the Miss Fortune vs Karthus matchup?
Karthus wins the matchup against Miss Fortune with a 63.2% win rate in League of Legends patch 26.4. The 26.3 percentage point advantage means Karthus is significantly favored in this lane matchup based on 21 games analyzed.
What is the best Miss Fortune build against Karthus?
The best Miss Fortune build against Karthus includes optimized core items. Check the matchup breakdown above for the full item path and build order.
What are the best Miss Fortune runes against Karthus?
The best Miss Fortune runes against Karthus use the Inspiration primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Miss Fortune vs Karthus matchup. See the full rune breakdown in the matchup comparison above.
Does Miss Fortune counter Karthus?
No, Miss Fortune struggles against Karthus with only a 36.8% win rate. Karthus has the advantage in this matchup. Miss Fortune players should focus on safe farming and avoiding extended trades to minimize Karthus's lead.
How do I play Miss Fortune against Karthus?
When playing Miss Fortune against Karthus, play cautiously and avoid Karthus's power spikes. Look for jungle assistance and team-dependent plays since Karthus has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.