- Win Rate
- 50.4%
- Pick Rate
- 7.3%
- Ban Rate
- 4.3%
Miss Fortune ADC Runes: Keystone & Shards
- Patch
- 26.20
- Games
- 14,528
- Lane
- Bot
- Tier
- All Tiers
- Last Updated
- Oct 18, 2026 UTC
- Methodology
- Data Methodology
- Author
- Dakota Chinnick
Best Bot Miss Fortune runes for LoL Patch 26.20 - First Strike from the Inspiration tree with Sorcery secondary (56.1% WR, 6.7% pick rate). Miss Fortune's optimal primary runes are First Strike, Cash Back, Biscuit Delivery, Jack Of All Trades. Secondary tree: Manaflow Band, Gathering Storm.
Primary Tree
Inspiration
First StrikeAttacks or abilities against an enemy champion within 0.25s of entering champion combat grant 10 gold and First Strike for 3 seconds, causing you to deal
Cooldown:
Cash BackGet 7.5% Gold back when you purchase Legendary Items.
Biscuit DeliveryBiscuit Delivery: Gain a Total Biscuit of Everlasting Will every 2 mins, until 6 min.
Biscuits restore 20 + 2% of your maximum health, increased by up to 100% based on missing Health. Consuming or selling a Biscuit permanently increases your max health by 30.
Jack Of All TradesFor each different stat gained from items, gain one Jack stack. Each stack grants you
Gain 8 or 20 bonus
Manaflow BandHitting an enemy champion with an ability permanently increases your maximum mana by 25, up to 250 mana.
After reaching 250 bonus mana, restore 1% of your missing mana every 5 seconds.
Cooldown: 15 seconds
Gathering StormEvery 10 min gain AP or AD,
10 min: + 8 AP or 5 AD
20 min: + 24 AP or 14 AD
30 min: + 48 AP or 29 AD
40 min: + 80 AP or 48 AD
50 min: + 120 AP or 72 AD
60 min: + 168 AP or 101 AD
etc...
Primary Tree
InspirationFirst StrikeAttacks or abilities against an enemy champion within 0.25s of entering champion combat grant 10 gold and First Strike for 3 seconds, causing you to deal
Cooldown:
Cash BackGet 7.5% Gold back when you purchase Legendary Items.
Biscuit DeliveryBiscuit Delivery: Gain a Total Biscuit of Everlasting Will every 2 mins, until 6 min.
Biscuits restore 20 + 2% of your maximum health, increased by up to 100% based on missing Health. Consuming or selling a Biscuit permanently increases your max health by 30.
Jack Of All TradesFor each different stat gained from items, gain one Jack stack. Each stack grants you
Gain 8 or 20 bonus
Gathering StormEvery 10 min gain AP or AD,
10 min: + 8 AP or 5 AD
20 min: + 24 AP or 14 AD
30 min: + 48 AP or 29 AD
40 min: + 80 AP or 48 AD
50 min: + 120 AP or 72 AD
60 min: + 168 AP or 101 AD
etc...
Manaflow BandHitting an enemy champion with an ability permanently increases your maximum mana by 25, up to 250 mana.
After reaching 250 bonus mana, restore 1% of your missing mana every 5 seconds.
Cooldown: 15 seconds
Every Miss Fortune Bot Keystone and Secondary Tree (Patch 26.20)
13,834 gamesMiss Fortune Bot runs First Strike in 58% of games, with a 51.3% win rate. Sorcery is the usual secondary tree (46%). Standard stat shards: Adaptive Force (offense), Adaptive Force (flex), Health (defense).
Keystones
| Rune | Players | Win Rate | Games |
|---|---|---|---|
| First StrikeMost played | 57.8% | 51.3% | 7,990 |
 Press the Attack | 34.1% | 50.1% | 4,717 |
 Lethal Tempo | 2.7% | 47.2% | 369 |
 Dark Harvest | 2.5% | 45.1% | 344 |
 Arcane Comet | 0.8% | 46.2% | 117 |
 Fleet Footwork | 0.6% | 43.0% | 79 |
Secondary trees
| Rune | Players | Win Rate | Games |
|---|---|---|---|
 SorceryMost played | 46.2% | 51.6% | 6,398 |
| Inspiration | 28.8% | 50.0% | 3,984 |
 Precision | 20.3% | 49.0% | 2,815 |
 Domination | 4.0% | 46.4% | 547 |
 Resolve | 0.6% | 48.3% | 87 |
Pick rate is the share of Miss Fortune games in this lane that used the rune; options under 40 games are left out. A higher win rate on a rarely picked rune is usually a matchup-specific choice, not a general upgrade.
Miss Fortune Minor Runes by Tree
Every minor rune Miss Fortune players take, grouped by rune tree, with how often it is picked and how often it wins.
Inspiration
| Rune | Players | Win Rate | Games |
|---|---|---|---|
| Biscuit DeliveryMost played | 78.7% | 51.0% | 10,883 |
| Cash Back | 46.9% | 51.6% | 6,492 |
 Magical Footwear | 38.8% | 50.3% | 5,373 |
 Cosmic Insight | 32.1% | 49.2% | 4,439 |
| Jack Of All Trades | 27.7% | 53.2% | 3,829 |
 Triple Tonic | 5.1% | 51.3% | 706 |
Precision
| Rune | Players | Win Rate | Games |
|---|---|---|---|
 Presence of MindMost played | 49.5% | 49.6% | 6,841 |
 Coup de Grace | 47.5% | 49.4% | 6,578 |
 Legend: Bloodline | 30.7% | 50.4% | 4,252 |
 Legend: Alacrity | 9.8% | 47.4% | 1,354 |
 Cut Down | 7.4% | 49.7% | 1,027 |
 Triumph | 6.3% | 50.2% | 874 |
Sorcery
| Rune | Players | Win Rate | Games |
|---|---|---|---|
| Gathering StormMost played | 44.1% | 51.6% | 6,094 |
| Manaflow Band | 41.8% | 51.4% | 5,785 |
 Absolute Focus | 3.1% | 49.3% | 430 |
 Scorch | 1.9% | 51.7% | 265 |
 Axiom Arcanist | 1.9% | 55.2% | 259 |
 Celerity | 1.7% | 46.8% | 235 |
Domination
| Rune | Players | Win Rate | Games |
|---|---|---|---|
 Ultimate HunterMost played | 4.5% | 46.6% | 629 |
 Taste of Blood | 3.5% | 41.2% | 478 |
 Cheap Shot | 3.1% | 49.2% | 435 |
 Grisly Mementos | 2.3% | 44.0% | 318 |
 Treasure Hunter | 1.4% | 41.6% | 190 |
 Relentless Hunter | 1.1% | 43.0% | 151 |
Miss Fortune Stat Shards
Which stat shards Miss Fortune players choose in each of the three shard rows, and the win rate of each.
| Rune | Players | Win Rate | Games |
|---|---|---|---|
 Adaptive Force (flex)Most played | 97.3% | 50.5% | 13,463 |
| Adaptive Force (offense) | 64.3% | 50.6% | 8,889 |
 Health (defense) | 48.4% | 51.5% | 6,700 |
| Health Scaling (defense) | 47.8% | 49.4% | 6,606 |
 Attack Speed (offense) | 34.9% | 49.9% | 4,832 |
 Tenacity and Slow Resist (defense) | 3.8% | 47.3% | 528 |
 Move Speed (flex) | 2.3% | 43.4% | 320 |
 Ability Haste (offense) | 0.8% | 48.7% | 113 |
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Miss Fortune Runes FAQ - Patch 26.20
What is the best keystone for Miss Fortune Bot?
First Strike: Miss Fortune Bot takes it in 58% of ranked games and wins 51.3% of 7,990 games. Alternatives: Press the Attack (34%, 50.1%), Lethal Tempo (3%, 47.2%).
What stat shards should Miss Fortune take?
Most Miss Fortune players take Adaptive Force (offense), Adaptive Force (flex), Health (defense) — one from each shard row.
What are the best Miss Fortune runes in patch 26.20?
The best Miss Fortune runes in patch 26.20 use the Inspiration tree with First Strike, Cash Back, Biscuit Delivery, and Jack Of All Trades, and the Sorcery tree with Manaflow Band and Gathering Storm. This rune setup achieves a 56.1% win rate with a 6.7% pick rate.
What is the win rate for Miss Fortune's best rune page?
Miss Fortune's best rune page has a 56.1% win rate in patch 26.20, which is +5.7% compared to Miss Fortune's average win rate. This rune setup has a 6.7% pick rate among Miss Fortune players.
What keystone should I use on Miss Fortune?
First Strike from the Inspiration tree is the best keystone rune for Miss Fortune in patch 26.20. This keystone synergizes well with Miss Fortune's kit and provides a 56.1% win rate.
What is Miss Fortune's primary rune tree?
Miss Fortune's primary rune tree is Inspiration. The optimal Inspiration runes for Miss Fortune are First Strike, Cash Back, Biscuit Delivery, and Jack Of All Trades, with First Strike being the keystone of choice.
What is Miss Fortune's secondary rune tree?
Miss Fortune's best secondary rune tree is Sorcery. The recommended Sorcery runes are Manaflow Band and Gathering Storm, which complement Miss Fortune's Inspiration primary tree.
What are alternative rune setups for Miss Fortune?
An alternative Miss Fortune rune setup uses First Strike from the Inspiration tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.
How popular are Miss Fortune's runes?
Miss Fortune's top rune page has a 6.7% pick rate in patch 26.20. This indicates that 6.7% of Miss Fortune players use the First Strike setup with Inspiration and Sorcery trees.