Seraphine - League of Legends Champion
Win Rate
52.4%
Pick Rate
10.0%

Seraphinevs Miss Fortune

SSupportMage
Patch26.14
Matches226,800
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 21, 2026
MethodologyData Methodology

Seraphine vs Miss Fortune is a decisive matchup in LoL patch 26.14. Seraphine wins with a 57.5% win rate (+15.0%) over Miss Fortune based on 80 games. Seraphine holds the advantage in both the early and late game. Below you'll find the best Seraphine build, runes, laning stats, and strategies for the Seraphine vs Miss Fortune matchup.

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Seraphine Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Seraphine performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Seraphine - 57.5% win rate in this matchup
Seraphine
57.5% WR
VS
Miss Fortune vs Seraphine matchup - 42.5% win rate
Miss Fortune
42.5% WR

Who Wins the Seraphine vs Miss Fortune Matchup?

Seraphine wins the Seraphine vs Miss Fortune matchup
Winner
Seraphine
Matches: 80
57.5%
Win Rate
42.5%
5.3
CS / min
5.9
724
DMG / min
818
11,206
Gold / game
12,918
141
Heal / min
165
388
DMG Mitigated / min
405
1.3
CC / min
0.3
59.3%
Early Game WR
40.7%
56.6%
Late Game WR
43.4%

Seraphine vs Miss Fortune Matchup Summary

The Seraphine vs Miss Fortune matchup is a decisive matchup in League of Legends ranked play. Based on 80 recent matches analyzed, Seraphine wins with a 57.5% win rate compared to Miss Fortune's 42.5%, giving Seraphine a 15.0 percentage point advantage. Seraphine dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Miss Fortune players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Seraphine leads by 1.0s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Seraphine players can confidently pick into Miss Fortune and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Miss Fortune away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Seraphine vs Miss Fortune Laning Phase Breakdown

Miss Fortune wins the laning phase against Seraphine in League of Legends

Miss Fortune is favored during the laning phase against Seraphine, winning 4 out of 5 key stat categories. Miss Fortune holds advantages in farming, damage, gold income and sustain, making them the stronger laner in this matchup.

Farming
5.3Seraphine
5.9Miss Fortune
Miss Fortune edges out Seraphine by 0.6 CS per minute — a moderate farming advantage that adds up to roughly 8 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Miss Fortune.
Damage
724Seraphine
818Miss Fortune
Miss Fortune heavily out-damages Seraphine by 94 DMG/min, dominating both short trades and all-in fights. Seraphine should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Miss Fortune's sustained damage advantage take over.
Economy
11,206Seraphine
12,918Miss Fortune
Miss Fortune generates a commanding 1,712 more gold per game than Seraphine. This substantial economic advantage means Miss Fortune consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Seraphine should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.3Seraphine
0.3Miss Fortune
Seraphine brings significantly more crowd control than Miss Fortune, with 1.0 more seconds of CC per minute. This large utility gap makes Seraphine far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Miss Fortune should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
529Seraphine
569Miss Fortune
Seraphine and Miss Fortune have comparable sustain profiles, with only 40 HP/min separating their healing and damage mitigation. Neither champion can out-attrition the other in lane, so trades will be decided by burst potential and ability usage rather than sustain.

Best Seraphine Build Against Miss Fortune

Ionian Boots of Lucidity is the optimal boots choice against Miss Fortune, providing the mobility and stats Seraphine needs most in this matchup. The top-performing core items for Seraphine against Miss Fortune are Echoes of Helia, Moonstone Renewer and Imperial Mandate. This combination gives Seraphine an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Miss Fortune. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Seraphine vs Miss Fortune matchup.

Early Game vs Late Game

Early Game
Seraphine
59.3%
+18.5% advantage
Seraphine early game win rateSeraphine59.3%
Miss Fortune early game win rateMiss Fortune40.7%
Late Game
Seraphine
56.6%
+13.2% advantage
Seraphine late game win rateSeraphine56.6%
Miss Fortune late game win rateMiss Fortune43.4%

Seraphine dominates the early game (first 15 minutes) with a commanding 59.3% win rate — a 18.5 percentage point lead over Miss Fortune. This lopsided early game means Seraphine can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Seraphine is far superior in the late game (25+ minutes), boasting a 56.6% win rate — 13.2 points above Miss Fortune. Extended games heavily favor Seraphine, whose kit and scaling make them a dominant force in team fights and objective control.

Seraphine holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Miss Fortune players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Seraphine Runes Against Miss Fortune

Sorcery rune tree - Seraphine primary runes vs Miss FortuneSorcery
Arcane Comet - best Seraphine rune vs Miss FortuneManaflow Band - best Seraphine rune vs Miss FortuneTranscendence - best Seraphine rune vs Miss FortuneGathering Storm - best Seraphine rune vs Miss Fortune
Precision rune tree - Seraphine secondary runes vs Miss FortunePrecision
Cut Down - best Seraphine rune vs Miss FortuneLegend: Haste - best Seraphine rune vs Miss Fortune
46.4% WR

Running Sorcery primary with Precision secondary allows Seraphine to press their advantage against Miss Fortune, amplifying the strengths that make this a favorable matchup.


Seraphine matchup data for League of Legends patch 26.14. The table below shows Seraphine's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Seraphine build, runes, laning stats, and early vs late game analysis for that specific matchup.

Seraphine matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
55.85%2991.74719,29548.1%60.0%
49.76%2071.55128,84357.0%45.3%
47.70%1741.55109,00848.0%47.4%
49.13%1731.44618,48850.0%48.5%
49.12%1711.64808,75953.7%46.1%
47.06%1531.55109,22549.1%45.8%
48.30%1471.95329,70651.0%46.9%
50.38%1331.54679,03049.0%51.2%
45.97%1241.44288,53360.0%36.5%
48.21%1121.44729,01753.3%44.8%
54.55%1102.35059,68744.4%59.5%
46.79%1091.55018,61150.0%44.4%
57.41%1081.45369,50765.8%52.2%
55.32%941.85399,07347.4%60.7%
50.56%891.44849,28360.0%45.8%
52.87%871.34668,26252.8%52.9%
57.65%851.54169,35765.6%52.8%
57.50%805.372411,20659.3%56.6%
45.45%771.64769,99525.0%50.8%
63.16%761.55059,33854.8%68.9%
57.89%761.75148,58067.6%48.7%
50.00%721.64569,53364.0%42.5%
50.00%662.04959,25747.8%51.2%
50.77%651.46317,61950.0%51.6%
53.85%656.077710,54060.0%48.6%
46.88%641.34479,18159.1%40.5%
52.46%611.54608,55950.0%54.0%
51.72%581.45178,94657.7%46.9%
53.45%581.35148,75145.5%58.3%
43.86%571.45249,59460.0%38.1%
54.55%551.55419,53777.8%43.2%
52.83%531.44887,86337.5%65.5%
52.94%513.765010,65950.0%54.3%
53.49%436.17089,63055.2%50.0%
56.10%411.44789,02957.1%55.0%
36.84%385.975311,16633.3%38.5%
51.52%331.55048,36043.8%58.8%
54.55%331.44978,85036.4%63.6%
62.50%325.476410,80441.7%75.0%
35.48%311.54698,95836.4%35.0%
54.84%311.94618,75463.6%50.0%
55.17%293.267211,13925.0%66.7%
60.71%284.15919,88872.7%52.9%
32.14%286.176410,58033.3%31.3%
69.23%265.776110,57085.7%50.0%
70.83%241.45079,19650.0%81.3%
56.52%236.182912,78350.0%60.0%
56.52%231.85069,03258.3%54.5%
47.62%213.564410,63366.7%40.0%
57.14%211.66148,42960.0%54.5%
42.86%211.648511,10033.3%44.4%
63.16%195.569112,81460.0%64.3%
63.16%191.75289,58566.7%60.0%
47.37%196.387810,25960.0%33.3%
50.00%186.580110,04650.0%50.0%
50.00%186.280711,85837.5%60.0%
50.00%186.885311,27550.0%50.0%
56.25%165.472113,6070.0%69.2%
50.00%164.861610,99950.0%50.0%
56.25%165.866011,976100.0%36.4%
75.00%162.24547,74077.8%71.4%
80.00%152.472410,151100.0%66.7%
66.67%152.474310,11660.0%70.0%
42.86%145.879310,92340.0%44.4%
61.54%131.44069,43660.0%62.5%
66.67%126.279211,77420.0%100.0%
33.33%125.16559,89640.0%28.6%
54.55%113.46429,30060.0%50.0%
40.00%101.35288,42020.0%60.0%
40.00%105.289411,60625.0%50.0%
80.00%102.254811,212100.0%71.4%
55.56%94.86278,88680.0%25.0%
44.44%96.47018,84342.9%50.0%
55.56%91.655510,08533.3%66.7%
25.00%85.075011,78850.0%16.7%
85.71%75.55249,75775.0%100.0%
57.14%71.55089,13366.7%50.0%
42.86%75.566910,94833.3%50.0%
85.71%76.187613,23166.7%100.0%
42.86%74.36429,62220.0%100.0%
57.14%73.050210,97250.0%60.0%
57.14%72.667710,02866.7%50.0%
71.43%73.04619,27766.7%75.0%
28.57%73.673212,7790.0%33.3%
66.67%65.886412,97750.0%75.0%
50.00%64.85639,34966.7%33.3%
33.33%66.786113,96850.0%25.0%
66.67%65.56098,223100.0%0.0%
83.33%64.062711,888100.0%80.0%
50.00%64.249210,633100.0%25.0%
100.00%64.68619,415100.0%100.0%
80.00%52.45339,18466.7%100.0%
60.00%51.55748,068100.0%33.3%
80.00%55.787512,964100.0%75.0%
40.00%51.64836,62350.0%33.3%
60.00%53.08026,67733.3%100.0%
100.00%52.36298,546100.0%100.0%
60.00%54.26028,77833.3%100.0%
60.00%54.74626,532100.0%33.3%
40.00%56.485013,194100.0%0.0%
20.00%53.473711,9840.0%33.3%
100.00%55.51,02313,201100.0%100.0%

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Seraphine vs Miss Fortune - Frequently Asked Questions

How does Seraphine do against Miss Fortune in League of Legends?

Seraphine wins the Seraphine vs Miss Fortune matchup with a 57.5% win rate compared to Miss Fortune's 42.5%, a 15.0 percentage point difference. This data is based on 80 recent ranked games in patch 26.14.

How does Seraphine do against Miss Fortune in the early game?

In the early game, Seraphine has the advantage against Miss Fortune with a 59.3% win rate versus 40.7%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Seraphine do against Miss Fortune in the late game?

In the late game, Seraphine takes over the Seraphine vs Miss Fortune matchup with a 56.6% win rate compared to 43.4%. Seraphine scales better into team fights and objective contests after 25 minutes.

Who wins the Seraphine vs Miss Fortune matchup?

Seraphine wins the matchup against Miss Fortune with a 57.5% win rate in League of Legends patch 26.14. The 15.0 percentage point advantage means Seraphine is significantly favored in this lane matchup based on 80 games analyzed.

What is the best Seraphine build against Miss Fortune?

The best Seraphine build against Miss Fortune includes Echoes of Helia, Moonstone Renewer, Imperial Mandate with Ionian Boots of Lucidity. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Seraphine runes against Miss Fortune?

The best Seraphine runes against Miss Fortune use the Sorcery primary tree with Precision secondary. This rune setup achieves a 46.4% win rate in the Seraphine vs Miss Fortune matchup. See the full rune breakdown in the matchup comparison above.

Does Seraphine counter Miss Fortune?

Yes, Seraphine has a favorable matchup against Miss Fortune with a 57.5% win rate. Seraphine strongly counters Miss Fortune in lane based on current patch 26.14 data.

How do I play Seraphine against Miss Fortune?

When playing Seraphine against Miss Fortune, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.