Qiyanavs Vayne
Qiyana vs Vayne is a decisive matchup in LoL patch 26.10. Vayne wins with a 80.0% win rate (+60.0%) over Qiyana based on 5 games. Vayne holds the advantage in both the early and late game. Below you'll find the best Qiyana build, runes, laning stats, and strategies for the Qiyana vs Vayne matchup.
Qiyana Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Qiyana performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Vayne(20.0%)Who Wins the Qiyana vs Vayne Matchup?
Qiyana vs Vayne Matchup Summary
The Qiyana vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Vayne wins with a 80.0% win rate compared to Qiyana's 20.0%, giving Vayne a 60.0 percentage point advantage. Vayne dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Qiyana players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Qiyana leads by 0.3s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne has a strong advantage in this matchup. Qiyana players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Vayne overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Qiyana vs Vayne Laning Phase Breakdown
Vayne is favored during the laning phase against Qiyana, winning 4 out of 5 key stat categories. Vayne holds advantages in farming, damage, gold income and sustain, making them the stronger laner in this matchup.
Best Qiyana Build Against Vayne
Immortal Path is the optimal boots choice against Vayne, providing the mobility and stats Qiyana needs most in this matchup. The top-performing core items for Qiyana against Vayne are Voltaic Cyclosword, Profane Hydra and Serylda's Grudge. This combination gives Qiyana an effective balance of damage, survivability, and utility for the matchup. This build achieves a solid 50.0% win rate across 2 games, proving it to be a reliable item path when facing Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Qiyana vs Vayne matchup.
Early Game vs Late Game
Qiyana0.0%Vayne100.0%Qiyana33.3%Vayne66.7%Vayne dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Qiyana. This lopsided early game means Vayne can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Vayne is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Qiyana. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.
Vayne holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Qiyana players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Qiyana Runes Against Vayne
Domination
Precision
The Domination and Precision rune setup gives Qiyana the best tools to compete against Vayne in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Qiyana matchup data for League of Legends patch 26.10. The table below shows Qiyana's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Qiyana build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 48.89% | 90 | 6.1 | 819 | 11,286 | 46.8% | 51.2% | |
| 34.83% | 89 | 5.9 | 820 | 11,612 | 32.4% | 36.5% | |
| 40.48% | 84 | 6.2 | 771 | 12,666 | 39.3% | 41.1% | |
| 51.25% | 80 | 5.9 | 967 | 12,209 | 52.6% | 50.0% | |
| 52.00% | 75 | 5.6 | 835 | 12,441 | 58.1% | 47.7% | |
| 39.66% | 58 | 6.0 | 907 | 11,585 | 48.5% | 28.0% | |
| 40.38% | 52 | 6.0 | 879 | 11,778 | 40.0% | 40.7% | |
| 41.67% | 48 | 5.8 | 757 | 12,467 | 50.0% | 37.5% | |
| 27.08% | 48 | 4.8 | 814 | 12,239 | 21.7% | 32.0% | |
| 54.35% | 46 | 5.4 | 905 | 11,951 | 46.1% | 65.0% | |
| 43.18% | 44 | 5.8 | 822 | 10,897 | 33.3% | 52.2% | |
| 45.24% | 42 | 3.9 | 817 | 12,253 | 38.9% | 50.0% | |
| 46.34% | 41 | 5.6 | 761 | 11,845 | 40.0% | 50.0% | |
| 31.71% | 41 | 5.2 | 826 | 10,961 | 22.7% | 42.1% | |
| 47.50% | 40 | 6.2 | 867 | 11,989 | 33.3% | 63.2% | |
| 51.28% | 39 | 5.6 | 925 | 11,692 | 38.9% | 61.9% | |
| 60.53% | 38 | 5.6 | 792 | 11,933 | 55.6% | 65.0% | |
| 37.84% | 37 | 1.1 | 790 | 13,959 | 50.0% | 30.4% | |
| 36.11% | 36 | 4.3 | 852 | 12,292 | 23.1% | 43.5% | |
| 60.00% | 35 | 5.9 | 855 | 11,436 | 56.3% | 63.2% | |
| 32.35% | 34 | 5.8 | 795 | 12,627 | 27.3% | 34.8% | |
| 54.55% | 33 | 6.0 | 776 | 11,866 | 46.7% | 61.1% | |
| 46.88% | 32 | 6.2 | 873 | 12,462 | 41.7% | 50.0% | |
| 51.61% | 31 | 5.8 | 901 | 13,811 | 54.5% | 50.0% | |
| 53.33% | 30 | 6.1 | 776 | 11,675 | 50.0% | 55.6% | |
| 44.83% | 29 | 1.1 | 791 | 13,927 | 28.6% | 60.0% | |
| 42.86% | 28 | 2.1 | 763 | 12,743 | 50.0% | 35.7% | |
| 42.86% | 28 | 6.0 | 915 | 13,157 | 40.0% | 44.4% | |
| 53.57% | 28 | 5.3 | 645 | 10,876 | 40.0% | 61.1% | |
| 61.54% | 26 | 5.6 | 791 | 11,844 | 46.1% | 76.9% | |
| 53.85% | 26 | 6.1 | 869 | 11,926 | 30.8% | 76.9% | |
| 46.15% | 26 | 6.0 | 1,062 | 13,534 | 45.5% | 46.7% | |
| 61.54% | 26 | 5.6 | 812 | 11,847 | 45.5% | 73.3% | |
| 45.83% | 24 | 6.2 | 885 | 11,580 | 42.9% | 50.0% | |
| 45.83% | 24 | 6.4 | 895 | 12,514 | 22.2% | 60.0% | |
| 33.33% | 24 | 1.3 | 730 | 12,048 | 42.9% | 20.0% | |
| 56.52% | 23 | 6.3 | 914 | 11,715 | 66.7% | 45.5% | |
| 47.83% | 23 | 1.9 | 769 | 13,571 | 50.0% | 46.7% | |
| 34.78% | 23 | 6.2 | 882 | 10,626 | 40.0% | 25.0% | |
| 59.09% | 22 | 6.3 | 961 | 13,175 | 66.7% | 53.9% | |
| 59.09% | 22 | 5.9 | 974 | 12,921 | 63.6% | 54.5% | |
| 57.14% | 21 | 3.9 | 820 | 12,583 | 57.1% | 57.1% | |
| 33.33% | 21 | 4.8 | 732 | 11,778 | 44.4% | 25.0% | |
| 52.38% | 21 | 1.4 | 912 | 13,742 | 22.2% | 75.0% | |
| 50.00% | 20 | 0.9 | 830 | 12,852 | 45.5% | 55.6% | |
| 47.37% | 19 | 3.6 | 780 | 10,706 | 44.4% | 50.0% | |
| 57.89% | 19 | 2.0 | 772 | 12,730 | 50.0% | 66.7% | |
| 42.11% | 19 | 5.8 | 778 | 11,267 | 40.0% | 44.4% | |
| 43.75% | 16 | 6.0 | 1,011 | 14,822 | 25.0% | 50.0% | |
| 46.67% | 15 | 1.3 | 729 | 14,255 | 28.6% | 62.5% | |
| 46.67% | 15 | 5.8 | 975 | 13,801 | 40.0% | 50.0% | |
| 46.15% | 13 | 6.1 | 794 | 12,189 | 60.0% | 37.5% | |
| 53.85% | 13 | 0.9 | 557 | 12,037 | 50.0% | 57.1% | |
| 61.54% | 13 | 4.8 | 799 | 10,238 | 50.0% | 71.4% | |
| 76.92% | 13 | 2.6 | 824 | 11,314 | 75.0% | 80.0% | |
| 53.85% | 13 | 1.0 | 776 | 11,505 | 50.0% | 60.0% | |
| 33.33% | 12 | 5.8 | 756 | 12,342 | 28.6% | 40.0% | |
| 50.00% | 12 | 5.6 | 881 | 10,972 | 57.1% | 40.0% | |
| 25.00% | 12 | 0.8 | 588 | 11,850 | 33.3% | 0.0% | |
| 75.00% | 12 | 6.7 | 1,020 | 12,537 | 85.7% | 60.0% | |
| 66.67% | 12 | 0.9 | 658 | 11,921 | 57.1% | 80.0% | |
| 45.45% | 11 | 6.3 | 1,075 | 11,512 | 42.9% | 50.0% | |
| 54.55% | 11 | 1.1 | 725 | 12,991 | 20.0% | 83.3% | |
| 54.55% | 11 | 2.3 | 634 | 12,391 | 66.7% | 50.0% | |
| 45.45% | 11 | 4.1 | 744 | 10,797 | 50.0% | 40.0% | |
| 60.00% | 10 | 1.3 | 796 | 13,898 | 66.7% | 57.1% | |
| 60.00% | 10 | 3.0 | 797 | 14,583 | 50.0% | 62.5% | |
| 60.00% | 10 | 5.9 | 839 | 12,686 | 50.0% | 66.7% | |
| 44.44% | 9 | 6.5 | 908 | 14,157 | 50.0% | 40.0% | |
| 33.33% | 9 | 1.5 | 703 | 13,076 | 20.0% | 50.0% | |
| 55.56% | 9 | 1.3 | 1,025 | 14,667 | 25.0% | 80.0% | |
| 11.11% | 9 | 6.2 | 594 | 8,888 | 0.0% | 50.0% | |
| 33.33% | 9 | 1.0 | 957 | 16,926 | 100.0% | 25.0% | |
| 44.44% | 9 | 1.9 | 823 | 16,290 | 50.0% | 42.9% | |
| 55.56% | 9 | 1.1 | 894 | 14,341 | 66.7% | 33.3% | |
| 37.50% | 8 | 4.0 | 688 | 13,780 | 100.0% | 28.6% | |
| 75.00% | 8 | 1.0 | 994 | 17,226 | 0.0% | 85.7% | |
| 50.00% | 8 | 4.4 | 587 | 10,605 | 42.9% | 100.0% | |
| 62.50% | 8 | 2.6 | 846 | 13,950 | 0.0% | 62.5% | |
| 50.00% | 8 | 1.9 | 813 | 12,279 | 40.0% | 66.7% | |
| 25.00% | 8 | 5.8 | 867 | 11,985 | 25.0% | 25.0% | |
| 25.00% | 8 | 6.7 | 974 | 14,138 | 50.0% | 16.7% | |
| 75.00% | 8 | 6.9 | 888 | 11,764 | 80.0% | 66.7% | |
| 28.57% | 7 | 2.4 | 682 | 10,105 | 0.0% | 50.0% | |
| 28.57% | 7 | 6.7 | 769 | 13,196 | 33.3% | 25.0% | |
| 71.43% | 7 | 0.8 | 834 | 16,170 | 66.7% | 75.0% | |
| 42.86% | 7 | 4.6 | 850 | 13,268 | 66.7% | 25.0% | |
| 85.71% | 7 | 2.1 | 834 | 12,875 | 100.0% | 50.0% | |
| 28.57% | 7 | 6.9 | 1,007 | 14,387 | 0.0% | 40.0% | |
| 57.14% | 7 | 1.1 | 863 | 13,320 | 100.0% | 0.0% | |
| 50.00% | 6 | 1.2 | 704 | 13,538 | 50.0% | 50.0% | |
| 33.33% | 6 | 3.3 | 1,045 | 16,968 | 0.0% | 33.3% | |
| 66.67% | 6 | 2.8 | 869 | 15,608 | 0.0% | 80.0% | |
| 50.00% | 6 | 1.6 | 1,114 | 14,043 | 0.0% | 75.0% | |
| 33.33% | 6 | 4.9 | 593 | 9,862 | 25.0% | 50.0% | |
| 66.67% | 6 | 5.3 | 1,079 | 15,108 | 50.0% | 75.0% | |
| 66.67% | 6 | 4.5 | 991 | 15,152 | 100.0% | 60.0% | |
| 66.67% | 6 | 5.7 | 974 | 15,922 | 0.0% | 66.7% | |
| 33.33% | 6 | 2.5 | 647 | 12,356 | 50.0% | 25.0% | |
| 60.00% | 5 | 2.1 | 703 | 11,714 | 66.7% | 50.0% | |
| 40.00% | 5 | 6.1 | 609 | 10,524 | 0.0% | 66.7% | |
| 20.00% | 5 | 4.2 | 788 | 10,608 | 0.0% | 33.3% | |
| 40.00% | 5 | 6.0 | 768 | 10,823 | 50.0% | 33.3% | |
| 40.00% | 5 | 4.1 | 753 | 13,394 | 66.7% | 0.0% | |
Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.
Qiyana vs Vayne - Frequently Asked Questions
How does Qiyana do against Vayne in League of Legends?
Vayne wins the Qiyana vs Vayne matchup with a 80.0% win rate compared to Qiyana's 20.0%, a 60.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.10.
How does Qiyana do against Vayne in the early game?
In the early game, Vayne has the advantage against Qiyana with a 100.0% win rate versus 0.0%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Qiyana do against Vayne in the late game?
In the late game, Vayne takes over the Qiyana vs Vayne matchup with a 66.7% win rate compared to 33.3%. Vayne scales better into team fights and objective contests after 25 minutes.
Who wins the Qiyana vs Vayne matchup?
Vayne wins the matchup against Qiyana with a 80.0% win rate in League of Legends patch 26.10. The 60.0 percentage point advantage means Vayne is significantly favored in this lane matchup based on 5 games analyzed.
What is the best Qiyana build against Vayne?
The best Qiyana build against Vayne includes Voltaic Cyclosword, Profane Hydra, Serylda's Grudge with Immortal Path. This build achieves a 50.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Qiyana runes against Vayne?
The best Qiyana runes against Vayne use the Domination primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Qiyana vs Vayne matchup. See the full rune breakdown in the matchup comparison above.
Does Qiyana counter Vayne?
No, Qiyana struggles against Vayne with only a 20.0% win rate. Vayne has the advantage in this matchup. Qiyana players should focus on safe farming and avoiding extended trades to minimize Vayne's lead.
How do I play Qiyana against Vayne?
When playing Qiyana against Vayne, play cautiously and avoid Vayne's power spikes. Look for jungle assistance and team-dependent plays since Vayne has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.