Qiyana - League of Legends Champion
Win Rate
44.8%
Pick Rate
1.6%

Qiyanavs Lissandra

FAssassin
Patch26.14
Matches491,560
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 21, 2026
MethodologyData Methodology

Qiyana vs Lissandra is a decisive matchup in LoL patch 26.14. Lissandra wins with a 87.5% win rate (+75.0%) over Qiyana based on 8 games. Lissandra holds the advantage in both the early and late game. Below you'll find the best Qiyana build, runes, laning stats, and strategies for the Qiyana vs Lissandra matchup.

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Qiyana Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Qiyana performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Qiyana - 12.5% win rate in this matchup
Qiyana
12.5% WR
VS
Lissandra vs Qiyana matchup - 87.5% win rate
Lissandra
87.5% WR

Who Wins the Qiyana vs Lissandra Matchup?

Lissandra wins the Qiyana vs Lissandra matchup
Winner
Lissandra
Matches: 8
12.5%
Win Rate
87.5%
4.7
CS / min
6.7
784
DMG / min
1,218
9,268
Gold / game
11,330
80
Heal / min
169
464
DMG Mitigated / min
445
0.7
CC / min
2.2
0.0%
Early Game WR
100.0%
33.3%
Late Game WR
66.7%

Qiyana vs Lissandra Matchup Summary

The Qiyana vs Lissandra matchup is a decisive matchup in League of Legends ranked play. Based on 8 recent matches analyzed, Lissandra wins with a 87.5% win rate compared to Qiyana's 12.5%, giving Lissandra a 75.0 percentage point advantage. Lissandra dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Qiyana players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Lissandra leads by 1.5s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Lissandra has a strong advantage in this matchup. Qiyana players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Lissandra overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Qiyana vs Lissandra Laning Phase Breakdown

Lissandra wins the laning phase against Qiyana in League of Legends

Lissandra is favored during the laning phase against Qiyana, winning 5 out of 5 key stat categories. Lissandra holds advantages in farming, damage, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
4.7Qiyana
6.7Lissandra
Lissandra significantly out-farms Qiyana by 2.0 CS per minute, accumulating an estimated 30 CS lead by mid game. This substantial farming gap gives Lissandra a major gold advantage and earlier item completions. Qiyana players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
784Qiyana
1,218Lissandra
Lissandra heavily out-damages Qiyana by 434 DMG/min, dominating both short trades and all-in fights. Qiyana should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Lissandra's sustained damage advantage take over.
Economy
9,268Qiyana
11,330Lissandra
Lissandra generates a commanding 2,062 more gold per game than Qiyana. This substantial economic advantage means Lissandra consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Qiyana should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.7Qiyana
2.2Lissandra
Lissandra brings significantly more crowd control than Qiyana, with 1.5 more seconds of CC per minute. This large utility gap makes Lissandra far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Qiyana should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
543Qiyana
615Lissandra
Lissandra heals and mitigates 72 more damage per minute than Qiyana, providing moderate extra durability. This sustain edge allows Lissandra to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Qiyana.

Best Qiyana Build Against Lissandra

Chainlaced Crushers is the optimal boots choice against Lissandra, providing the mobility and stats Qiyana needs most in this matchup. The top-performing core items for Qiyana against Lissandra are Profane Hydra, Serylda's Grudge and Edge of Night. This combination gives Qiyana an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Qiyana vs Lissandra matchup.

Early Game vs Late Game

Early Game
Lissandra
100.0%
+100.0% advantage
Qiyana early game win rateQiyana0.0%
Lissandra early game win rateLissandra100.0%
Late Game
Lissandra
66.7%
+33.3% advantage
Qiyana late game win rateQiyana33.3%
Lissandra late game win rateLissandra66.7%

Lissandra dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Qiyana. This lopsided early game means Lissandra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Lissandra is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Qiyana. Extended games heavily favor Lissandra, whose kit and scaling make them a dominant force in team fights and objective control.

Lissandra holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Qiyana players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Qiyana Runes Against Lissandra

Domination rune tree - Qiyana primary runes vs LissandraDomination
Electrocute - best Qiyana rune vs LissandraSudden Impact - best Qiyana rune vs LissandraGrisly Mementos - best Qiyana rune vs LissandraTreasure Hunter - best Qiyana rune vs Lissandra
Precision rune tree - Qiyana secondary runes vs LissandraPrecision
Last Stand - best Qiyana rune vs LissandraPresence of Mind - best Qiyana rune vs Lissandra
0.0% WR

The Domination and Precision rune setup gives Qiyana the best tools to compete against Lissandra in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Qiyana matchup data for League of Legends patch 26.14. The table below shows Qiyana's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Qiyana build, runes, laning stats, and early vs late game analysis for that specific matchup.

Qiyana matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
45.76%594.284212,38338.1%50.0%
56.14%574.991912,54645.8%63.6%
36.73%491.475211,32534.8%38.5%
38.64%445.892412,02835.0%41.7%
53.66%416.390512,01361.1%47.8%
55.00%404.380812,78550.0%57.1%
42.50%403.589513,23741.7%42.9%
50.00%381.265912,83440.0%56.5%
54.05%376.29079,61160.9%42.9%
40.54%370.961511,73033.3%45.5%
58.33%361.275814,07650.0%61.5%
40.00%353.474711,84850.0%33.3%
41.18%345.392710,25457.1%30.0%
35.29%345.988812,66116.7%45.5%
38.24%341.065311,58738.9%37.5%
33.33%336.083111,33133.3%33.3%
35.48%311.066212,61640.0%33.3%
35.71%285.17909,64028.6%42.9%
42.86%281.274113,78155.6%36.8%
40.00%251.077712,01233.3%43.8%
40.91%221.276313,03237.5%42.9%
59.09%226.994911,33553.3%71.4%
45.00%205.777510,05254.5%33.3%
50.00%202.085112,88350.0%50.0%
36.84%195.994913,91766.7%31.3%
38.89%185.06649,84320.0%62.5%
33.33%181.171013,67220.0%38.5%
33.33%181.266713,65583.3%8.3%
35.29%172.567212,30716.7%45.5%
47.06%175.577312,15320.0%58.3%
37.50%165.893111,97242.9%33.3%
56.25%161.273912,64533.3%70.0%
37.50%165.41,05512,97216.7%50.0%
46.67%155.874512,64842.9%50.0%
66.67%151.41,04214,42050.0%72.7%
33.33%150.871612,01928.6%37.5%
50.00%141.180910,86428.6%71.4%
35.71%140.967212,24633.3%37.5%
30.77%131.078211,85225.0%33.3%
30.77%135.972510,82833.3%28.6%
30.77%131.168811,90328.6%33.3%
38.46%130.768711,64140.0%37.5%
50.00%126.173110,88857.1%40.0%
33.33%126.37758,17933.3%33.3%
75.00%123.671410,38966.7%83.3%
45.45%117.098012,36880.0%16.7%
54.55%115.892411,18828.6%100.0%
45.45%111.45549,89550.0%33.3%
50.00%105.880512,61333.3%57.1%
30.00%100.874712,94650.0%16.7%
70.00%102.585510,30050.0%83.3%
40.00%105.389011,7330.0%44.4%
22.22%91.487214,9870.0%25.0%
55.56%95.789413,2600.0%62.5%
55.56%91.079210,16440.0%75.0%
77.78%96.468912,624100.0%71.4%
33.33%90.852810,37940.0%25.0%
33.33%91.591912,14150.0%20.0%
50.00%81.86557,62020.0%100.0%
25.00%80.779811,94050.0%0.0%
12.50%84.77849,2680.0%33.3%
75.00%81.993015,29650.0%100.0%
25.00%84.486911,4940.0%40.0%
71.43%71.270610,65950.0%80.0%
71.43%74.277510,374100.0%50.0%
42.86%71.689511,24033.3%100.0%
42.86%71.176813,03750.0%33.3%
28.57%75.580110,63925.0%33.3%
57.14%75.893213,491100.0%50.0%
28.57%70.963211,43725.0%33.3%
42.86%71.277913,9480.0%50.0%
33.33%61.659312,33233.3%33.3%
50.00%65.15505,98750.0%0.0%
0.00%63.088012,2810.0%0.0%
33.33%62.460912,7700.0%40.0%
50.00%65.89299,53966.7%33.3%
33.33%65.383512,6660.0%50.0%
33.33%62.689910,44150.0%25.0%
40.00%55.18427,92840.0%0.0%
60.00%54.986911,304100.0%50.0%
60.00%55.057911,14233.3%100.0%
0.00%51.074815,2460.0%0.0%
40.00%52.985015,4850.0%40.0%
100.00%55.571713,793100.0%100.0%
20.00%55.98959,0070.0%50.0%
60.00%55.776010,62433.3%100.0%
60.00%53.41,06411,150100.0%33.3%
40.00%55.982014,9770.0%50.0%

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Qiyana vs Lissandra - Frequently Asked Questions

How does Qiyana do against Lissandra in League of Legends?

Lissandra wins the Qiyana vs Lissandra matchup with a 87.5% win rate compared to Qiyana's 12.5%, a 75.0 percentage point difference. This data is based on 8 recent ranked games in patch 26.14.

How does Qiyana do against Lissandra in the early game?

In the early game, Lissandra has the advantage against Qiyana with a 100.0% win rate versus 0.0%. Lissandra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Qiyana do against Lissandra in the late game?

In the late game, Lissandra takes over the Qiyana vs Lissandra matchup with a 66.7% win rate compared to 33.3%. Lissandra scales better into team fights and objective contests after 25 minutes.

Who wins the Qiyana vs Lissandra matchup?

Lissandra wins the matchup against Qiyana with a 87.5% win rate in League of Legends patch 26.14. The 75.0 percentage point advantage means Lissandra is significantly favored in this lane matchup based on 8 games analyzed.

What is the best Qiyana build against Lissandra?

The best Qiyana build against Lissandra includes Profane Hydra, Serylda's Grudge, Edge of Night with Chainlaced Crushers. Check the matchup breakdown above for the full item path and build order.

What are the best Qiyana runes against Lissandra?

The best Qiyana runes against Lissandra use the Domination primary tree with Precision secondary. This rune setup achieves a 0.0% win rate in the Qiyana vs Lissandra matchup. See the full rune breakdown in the matchup comparison above.

Does Qiyana counter Lissandra?

No, Qiyana struggles against Lissandra with only a 12.5% win rate. Lissandra has the advantage in this matchup. Qiyana players should focus on safe farming and avoiding extended trades to minimize Lissandra's lead.

How do I play Qiyana against Lissandra?

When playing Qiyana against Lissandra, play cautiously and avoid Lissandra's power spikes. Look for jungle assistance and team-dependent plays since Lissandra has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.