Qiyana, League of Legends champion
Win Rate
46.4%
Pick Rate
2.5%
Ban Rate
2.5%

Qiyana vs Lissandra

Qiyana F TierAssassin
Patch
26.19
Games
5,048
Lane
All Lanes
Tier
All Tiers
Last Updated
Oct 8, 2026 UTC
Methodology
Data Methodology

Qiyana vs Lissandra is a very close matchup in LoL patch 26.19. Qiyana wins with a 50.0% win rate (+0.0%) over Lissandra based on 16 games. Qiyana holds the advantage in both the early and late game. Below you'll find the best Qiyana build, runes, laning stats, and strategies for the Qiyana vs Lissandra matchup.

Qiyana Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Qiyana performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Qiyana
Qiyana
51.4%
VS
Lissandra
48.6%
Lissandra

Who wins Qiyana vs Lissandra?

Even matchupLow confidence

Qiyana wins 51.4% of these games. With this many games the true rate is most likely between 35.9% and 66.6% (95% range).

Expected
46.5%
From both champions' overall Mid win rates
Matchup effect
+4.9 pts
Observed minus expected
Sample
37 games
Lane: Mid
vs patch 26.18
—
Not enough games on both patches

Lane: Mid · Ranked Solo/Duo & Flex · North America server · All ranks · Patch 26.19 · Sep 24 – Sep 28

Key takeaways

  • Qiyana vs Lissandra is an even matchup: Qiyana wins 51.4% of 37 games, and the 95% range (35.9–66.6%) comfortably includes 50%.
  • Both champions' overall Mid win rates predict 46.5% for Qiyana; the result is within the margin of error of that, so this matchup mostly reflects the two champions' general strength.
  • Qiyana usually wins the lane: 607 gold ahead of Lissandra at 15 minutes on average (35 games with a 15-minute snapshot).
  • Qiyana players pick Profane Hydra much less often against Lissandra: 59.1% of their other Mid games, 37.8% here.
How we calculate this

Games: ranked Solo/Duo and Flex games on the North America server from the patch shown. Remakes (games under 5 minutes) are excluded.

A game only counts when Qiyana and Lissandra played the same position on opposite teams, so roaming, lane swaps within a team or a champion merely being in the same game never count as this matchup.

The 95% range is a Wilson score interval. Confidence comes from how wide that range is: within ±3 points is very high, ±5 high, ±8 moderate, anything wider low. Below 20 games a matchup is not classified at all.

Expected win rate combines both champions’ win rates in this lane (same games and filters) with the log5 formula: E = A(1−B) / (A(1−B) + B(1−A)). Matchup effect = observed − expected.

"What changes" compares Qiyana's choices in this matchup with the same champion's other games in the same lane, and lists a change only when it is at least 3 points and statistically significant (two-proportion z-test, |z| ≥ 2, 20+ games).

Results are not split by rank: the sample per rank is too small for honest per-rank matchup numbers.

Qiyana vs Lissandra Laning Stats

QiyanaLissandra

At 15 minutes

Gold difference
+607
Qiyana ahead
95% range +104 to +1,110
XP difference
−36
Within the margin of error
95% range −518 to +447
CS difference
−8.1
Lissandra ahead
95% range −15.7 to −0.4
4.80
Kills before 15 min
2.43
2.94
Deaths before 15 min
3.09
1.73
Solo kills before 15 min
0.89
13.5%
First blood
10.8%

Whole-game averages

5.7
CS / min
6.5
934
DMG / min
816
12,865
Gold / game
12,041
131
Heal / min
152
517
DMG Mitigated / min
455
0.7
CC / min
1.6

Qiyana vs Lissandra Win Rate by Game Length

Qiyana's win rate against Lissandra by game length. The dot is the win rate, the bar its 95% range and the dashed line the champion's usual win rate at that length. Lengths with fewer than 25 games are left blank.

Too few games
Under 20 min
5 games
Too few games
20–25 min
4 games
Too few games
25–30 min
6 games
Too few games
30–35 min
14 games
Too few games
35+ min
8 games
Qiyana vs Lissandra95% rangeQiyana usual (Mid)

No game length stands out: Qiyana's results against Lissandra in short and long games are within the margin of error of each other.

Qiyana vs Lissandra Power Spikes

Who is ahead at each stage, measured from these games. A stage reads "Even" when the difference is inside the margin of error, and "Insufficient data" when there are too few games to tell.

  1. Lane (15 min)QiyanaQiyana gold at 15: +607
  2. First itemInsufficient data
  3. Games under 20 minInsufficient data
  4. 20–30 min gamesInsufficient data
  5. 30+ min gamesInsufficient data

What Qiyana Changes Against Lissandra

Choices Qiyana players make noticeably more or less often in this matchup than in their other Mid games.

  • Profane Hydra
    Usually
    59.1%
    vs Lissandra
    37.8%
    −21.3 pts
  • Crimson Lucidity
    Usually
    57.3%
    vs Lissandra
    40.5%
    −16.8 pts
  • Health Scaling (defense)
    Health Scaling (defense)Stat shard
    Usually
    70.0%
    vs Lissandra
    54.1%
    −16.0 pts55.0% WR here
  • Chainlaced Crushers
    Usually
    13.7%
    vs Lissandra
    27.0%
    +13.3 pts
  • Lord Dominik's Regards
    Usually
    6.4%
    vs Lissandra
    18.9%
    +12.5 pts
  • Long SwordRefillable PotionStealth Ward
    Long Sword + Refillable Potion + Stealth WardStarting items
    Usually
    3.9%
    vs Lissandra
    13.5%
    +9.6 pts
  • Umbral Glaive
    Usually
    7.0%
    vs Lissandra
    16.2%
    +9.2 pts
  • Doran's ShieldHealth PotionStealth Ward
    Doran's Shield + Health Potion + Stealth WardStarting items
    Usually
    1.9%
    vs Lissandra
    8.1%
    +6.3 pts

Best Qiyana Build vs Lissandra

Usual Qiyana build (Mid)

81.8% win rate · 11 games

Against Lissandra

Not enough matchup-specific build data: only 3 of 25 Qiyana games against Lissandra carried a complete build, which is too few to recommend an item path from. Use Qiyana's standard build instead.

  • Lissandra usually completes Malignance first, at 10.6 min (median of 23 games).
  • Skill priority: Q > W > E — the same as usual.

Builds are ranked by the lower edge of their win rate range, not the raw win rate, so a build seen in a handful of wins never outranks a proven one.

Best Qiyana Runes vs Lissandra

Usual Qiyana runes (Mid)

ElectrocuteElectrocute
Domination
Sudden ImpactSixth SenseTreasure Hunter
Precision
Presence of MindLast Stand
Adaptive Force (offense)Adaptive Force (flex)Health (defense)

56.7% win rate · 67 games

Against Lissandra

Too few games for a matchup-specific rune page yet — use the usual page.

MetaBot Desktop

Plan your Qiyana draft in Draft Lab

Draft Lab lays out both teams lane by lane with live matchup win rates, damage profiles and game-phase lean, and suggests picks and bans from current meta data.

  • Full 5v5 draft board
  • Lane matchup win rates
  • Pick and ban suggestions
Draft Lab in MetaBot Desktop

Qiyana matchup data for League of Legends patch 26.19. The table below shows Qiyana's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Qiyana build, runes, laning stats, and early vs late game analysis for that specific matchup.

Other Qiyana Matchups

Win rate and games for each matchup. Lists are ranked by the edge of the 95% range so small samples cannot top them; matchups with at least 50 games only.

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Qiyana vs Lissandra FAQ - Patch 26.19

Who wins Qiyana vs Lissandra?

Qiyana vs Lissandra is an even matchup: Qiyana wins 51.4% of 37 games, and the 95% range (35.9–66.6%) comfortably includes 50%.

What is Qiyana's win rate against Lissandra?

Qiyana wins 51.4% of 37 Mid games against Lissandra on patch 26.19 (95% range 35.9–66.6%). Based on both champions' overall Mid win rates, 46.5% would be expected.

Does Qiyana counter Lissandra?

Not clearly. Qiyana wins 51.4% of 37 games against Lissandra, and the 95% range (35.9–66.6%) includes 50%, so neither champion reliably counters the other on current data.

Who wins lane, Qiyana or Lissandra?

Qiyana usually wins the lane: 607 gold ahead of Lissandra at 15 minutes on average (35 games with a 15-minute snapshot).

Does Qiyana outscale Lissandra?

There are too few games of each length to tell yet.

When is Lissandra strongest against Qiyana?

On current data there is no stage of the game where Lissandra is ahead of Qiyana beyond the margin of error.

What should Qiyana build against Lissandra?

There are not enough games for a matchup-specific core, so use Qiyana's usual Mid core: Voltaic Cyclosword, Profane Hydra, Death's Dance. The biggest change against Lissandra: Profane Hydra (59.1% usually, 37.8% here).

What runes should Qiyana use against Lissandra?

Use Qiyana's usual Electrocute page (Domination + Precision); there are too few games for a matchup-specific page. The biggest change against Lissandra: Health Scaling (defense) (70.0% usually, 54.1% here).