Qiyana - League of Legends Champion
Win Rate
45.8%
Pick Rate
1.0%

Qiyanavs Lissandra

FAssassin
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 21, 2026
MethodologyData Methodology

Qiyana vs Lissandra is a decisive matchup in LoL patch 26.7. Lissandra wins with a 64.7% win rate (+29.4%) over Qiyana based on 17 games. Lissandra wins the early laning phase while Qiyana scales better into the late game. Below you'll find the best Qiyana build, runes, laning stats, and strategies for the Qiyana vs Lissandra matchup.

Qiyana Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Qiyana performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Lissandra - 35.3% win rateLissandra(35.3%)
Qiyana - 35.3% win rate in this matchup
Qiyana
35.3% WR
VS
Lissandra vs Qiyana matchup - 64.7% win rate
Lissandra
64.7% WR

Who Wins the Qiyana vs Lissandra Matchup?

Lissandra wins the Qiyana vs Lissandra matchup
Winner
Lissandra
Matches: 17
35.3%
Win Rate
64.7%
6.6
CS / min
7.2
833
DMG / min
903
10,927
Gold / game
11,489
107
Heal / min
155
473
DMG Mitigated / min
452
0.7
CC / min
1.8
20.0%
Early Game WR
80.0%
57.1%
Late Game WR
42.9%

Qiyana vs Lissandra Matchup Summary

The Qiyana vs Lissandra matchup is a decisive matchup in League of Legends ranked play. Based on 17 recent matches analyzed, Lissandra wins with a 64.7% win rate compared to Qiyana's 35.3%, giving Lissandra a 29.4 percentage point advantage. Game phase dynamics play a critical role here: Lissandra controls the early laning stage, but Qiyana outscales as the game goes longer. The matchup shifts dramatically depending on game length — Lissandra needs to press advantages before Qiyana reaches their power spikes, while Qiyana should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Lissandra leads by 1.1s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Lissandra has a strong advantage in this matchup. Qiyana players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Lissandra overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Qiyana vs Lissandra Laning Phase Breakdown

Lissandra wins the laning phase against Qiyana in League of Legends

Lissandra is favored during the laning phase against Qiyana, winning 5 out of 5 key stat categories. Lissandra holds advantages in farming, damage, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
6.6Qiyana
7.2Lissandra
Lissandra edges out Qiyana by 0.6 CS per minute — a moderate farming advantage that adds up to roughly 9 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Lissandra.
Damage
833Qiyana
903Lissandra
Lissandra deals 70 more champion damage per minute than Qiyana. While noticeable in extended trades, this gap can be offset by Qiyana choosing favorable fight windows, such as engaging when Lissandra's key abilities are on cooldown or trading immediately after dodging a skillshot.
Economy
10,927Qiyana
11,489Lissandra
Lissandra earns 562 more gold per game than Qiyana, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Lissandra slightly faster item completions.
Utility
0.7Qiyana
1.8Lissandra
Lissandra brings significantly more crowd control than Qiyana, with 1.1 more seconds of CC per minute. This large utility gap makes Lissandra far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Qiyana should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
580Qiyana
607Lissandra
Qiyana and Lissandra have comparable sustain profiles, with only 27 HP/min separating their healing and damage mitigation. Neither champion can out-attrition the other in lane, so trades will be decided by burst potential and ability usage rather than sustain.

Best Qiyana Build Against Lissandra

Chainlaced Crushers is the optimal boots choice against Lissandra, providing the mobility and stats Qiyana needs most in this matchup. The top-performing core items for Qiyana against Lissandra are Profane Hydra, Hubris and Serylda's Grudge. This combination gives Qiyana an effective balance of damage, survivability, and utility for the matchup. This build has a 33.3% win rate across 3 games. While the overall matchup may be difficult, this item path gives Qiyana the best chance to compete against Lissandra. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Qiyana vs Lissandra matchup.

Early Game vs Late Game

Early Game
Lissandra
80.0%
+60.0% advantage
Qiyana early game win rateQiyana20.0%
Lissandra early game win rateLissandra80.0%
Late Game
Qiyana
57.1%
+14.3% advantage
Qiyana late game win rateQiyana57.1%
Lissandra late game win rateLissandra42.9%

Lissandra dominates the early game (first 15 minutes) with a commanding 80.0% win rate — a 60.0 percentage point lead over Qiyana. This lopsided early game means Lissandra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Qiyana is far superior in the late game (25+ minutes), boasting a 57.1% win rate — 14.3 points above Lissandra. Extended games heavily favor Qiyana, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Lissandra must aggressively press their early advantage and close out the game before Qiyana reaches their scaling breakpoints. If Qiyana survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Qiyana Runes Against Lissandra

Domination rune tree - Qiyana primary runes vs LissandraDomination
Electrocute - best Qiyana rune vs LissandraSudden Impact - best Qiyana rune vs LissandraSixth Sense - best Qiyana rune vs LissandraTreasure Hunter - best Qiyana rune vs Lissandra
Precision rune tree - Qiyana secondary runes vs LissandraPrecision
Presence of Mind - best Qiyana rune vs LissandraLast Stand - best Qiyana rune vs Lissandra
100.0% WR

The Domination and Precision rune setup gives Qiyana the best tools to compete against Lissandra in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Qiyana matchup data for League of Legends patch 26.7. The table below shows Qiyana's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Qiyana build, runes, laning stats, and early vs late game analysis for that specific matchup.

Qiyana matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
52.08%486.285012,39343.5%60.0%
42.86%356.487512,53846.7%40.0%
50.00%326.394412,71960.0%41.2%
50.00%306.485212,18350.0%50.0%
51.85%275.983212,46636.4%62.5%
38.46%266.590610,93826.7%54.5%
38.46%266.379110,61037.5%40.0%
60.00%255.796814,23853.3%70.0%
60.87%235.986212,21771.4%56.3%
45.45%226.484811,59866.7%20.0%
63.64%225.31,03012,91870.0%58.3%
45.00%206.082412,23350.0%40.0%
52.63%196.094114,24957.1%50.0%
52.94%176.591513,46962.5%44.4%
35.29%176.683310,92720.0%57.1%
47.06%174.259811,83257.1%40.0%
56.25%166.495913,01557.1%55.6%
37.50%166.589912,60212.5%62.5%
31.25%166.775512,12650.0%12.5%
73.33%156.385912,64875.0%71.4%
46.67%156.377912,28528.6%62.5%
66.67%154.91,05814,89480.0%60.0%
57.14%146.386611,81342.9%71.4%
50.00%145.989111,93966.7%37.5%
38.46%133.772311,68260.0%25.0%
30.77%133.693314,6470.0%40.0%
46.15%131.981614,31933.3%57.1%
66.67%124.892811,69980.0%57.1%
16.67%126.085312,76033.3%0.0%
50.00%125.977912,63425.0%62.5%
63.64%110.964110,48757.1%75.0%
36.36%116.584814,45620.0%50.0%
54.55%116.083910,94250.0%60.0%
40.00%106.391511,77450.0%25.0%
40.00%105.587811,26740.0%40.0%
50.00%106.31,03213,17750.0%50.0%
44.44%95.469312,34650.0%40.0%
44.44%91.274715,5620.0%44.4%
55.56%95.71,03513,20150.0%60.0%
44.44%96.28979,77360.0%25.0%
77.78%96.31,00813,165100.0%66.7%
28.57%76.795415,74750.0%20.0%
57.14%71.797216,36360.0%50.0%
42.86%76.086711,97366.7%25.0%
57.14%71.075414,31850.0%60.0%
33.33%62.264510,98250.0%25.0%
66.67%65.491415,73450.0%75.0%
50.00%61.075912,05333.3%66.7%
50.00%65.579513,6770.0%75.0%
66.67%61.270913,39933.3%100.0%
33.33%61.662012,5370.0%66.7%
33.33%62.692413,0180.0%50.0%
100.00%52.41,07615,530100.0%100.0%
60.00%55.65918,52066.7%50.0%
60.00%50.969412,982100.0%33.3%
20.00%51.459810,8600.0%33.3%
80.00%56.594011,435100.0%50.0%
0.00%51.773814,7350.0%0.0%
40.00%56.290114,603100.0%25.0%

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Qiyana vs Lissandra - Frequently Asked Questions

How does Qiyana do against Lissandra in League of Legends?

Lissandra wins the Qiyana vs Lissandra matchup with a 64.7% win rate compared to Qiyana's 35.3%, a 29.4 percentage point difference. This data is based on 17 recent ranked games in patch 26.7.

How does Qiyana do against Lissandra in the early game?

In the early game, Lissandra has the advantage against Qiyana with a 80.0% win rate versus 20.0%. Lissandra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Qiyana do against Lissandra in the late game?

In the late game, Qiyana takes over the Qiyana vs Lissandra matchup with a 57.1% win rate compared to 42.9%. Qiyana scales better into team fights and objective contests after 25 minutes.

Who wins the Qiyana vs Lissandra matchup?

Lissandra wins the matchup against Qiyana with a 64.7% win rate in League of Legends patch 26.7. The 29.4 percentage point advantage means Lissandra is significantly favored in this lane matchup based on 17 games analyzed.

What is the best Qiyana build against Lissandra?

The best Qiyana build against Lissandra includes Profane Hydra, Hubris, Serylda's Grudge with Chainlaced Crushers. This build achieves a 33.3% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Qiyana runes against Lissandra?

The best Qiyana runes against Lissandra use the Domination primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Qiyana vs Lissandra matchup. See the full rune breakdown in the matchup comparison above.

Does Qiyana counter Lissandra?

No, Qiyana struggles against Lissandra with only a 35.3% win rate. Lissandra has the advantage in this matchup. Qiyana players should focus on safe farming and avoiding extended trades to minimize Lissandra's lead.

How do I play Qiyana against Lissandra?

When playing Qiyana against Lissandra, play cautiously and avoid Lissandra's power spikes. Focus on safe farming — you outscale Lissandra in the late game. Use the matchup-specific build and runes above to optimize your chances.