
Qiyanavs Karthus
Qiyana vs Karthus is a decisive matchup in LoL patch 26.9. Karthus wins with a 80.0% win rate (+60.0%) over Qiyana based on 5 games. Karthus wins the early laning phase while Qiyana scales better into the late game. Below you'll find the best Qiyana build, runes, laning stats, and strategies for the Qiyana vs Karthus matchup.
Qiyana Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Qiyana performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Qiyana vs Karthus Matchup?

Qiyana vs Karthus Matchup Summary
The Qiyana vs Karthus matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Karthus wins with a 80.0% win rate compared to Qiyana's 20.0%, giving Karthus a 60.0 percentage point advantage. Game phase dynamics play a critical role here: Karthus controls the early laning stage, but Qiyana outscales as the game goes longer. The matchup shifts dramatically depending on game length — Karthus needs to press advantages before Qiyana reaches their power spikes, while Qiyana should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Qiyana leads by 0.3s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Karthus has a strong advantage in this matchup. Qiyana players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Karthus overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Qiyana vs Karthus Laning Phase Breakdown
Karthus is favored during the laning phase against Qiyana, winning 3 out of 5 key stat categories. Karthus holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.
Best Qiyana Build Against Karthus
Slightly Magical Footwear is the optimal boots choice against Karthus, providing the mobility and stats Qiyana needs most in this matchup. The top-performing core items for Qiyana against Karthus are Voltaic Cyclosword, Axiom Arc and Edge of Night. This combination gives Qiyana an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Qiyana vs Karthus matchup.
Early Game vs Late Game
Karthus dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Qiyana. This lopsided early game means Karthus can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Qiyana is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Karthus. Extended games heavily favor Qiyana, whose kit and scaling make them a dominant force in team fights and objective control.
This matchup features a dramatic power shift: Karthus must aggressively press their early advantage and close out the game before Qiyana reaches their scaling breakpoints. If Qiyana survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.
Best Qiyana Runes Against Karthus
The Domination and Precision rune setup gives Qiyana the best tools to compete against Karthus in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Qiyana matchup data for League of Legends patch 26.9. The table below shows Qiyana's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Qiyana build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 53.33% | 45 | 6.3 | 799 | 11,747 | 56.0% | 50.0% | |
| 37.21% | 43 | 6.2 | 766 | 12,073 | 44.4% | 32.0% | |
| 48.78% | 41 | 6.1 | 877 | 11,856 | 62.5% | 40.0% | |
| 45.00% | 40 | 6.1 | 852 | 12,620 | 52.9% | 39.1% | |
| 62.16% | 37 | 6.6 | 900 | 13,547 | 61.5% | 62.5% | |
| 48.57% | 35 | 6.6 | 881 | 11,459 | 45.5% | 53.9% | |
| 35.29% | 34 | 4.0 | 741 | 10,622 | 22.7% | 58.3% | |
| 50.00% | 32 | 6.0 | 755 | 11,376 | 42.9% | 55.6% | |
| 56.25% | 32 | 6.2 | 727 | 10,957 | 64.3% | 50.0% | |
| 51.85% | 27 | 6.3 | 913 | 12,523 | 64.3% | 38.5% | |
| 51.85% | 27 | 6.5 | 910 | 11,969 | 37.5% | 72.7% | |
| 50.00% | 26 | 5.9 | 715 | 10,004 | 40.0% | 63.6% | |
| 38.46% | 26 | 5.5 | 841 | 11,139 | 29.4% | 55.6% | |
| 45.83% | 24 | 4.6 | 865 | 11,996 | 42.9% | 50.0% | |
| 59.09% | 22 | 6.0 | 794 | 12,301 | 66.7% | 53.9% | |
| 45.45% | 22 | 6.4 | 897 | 12,607 | 33.3% | 53.9% | |
| 38.10% | 21 | 4.2 | 647 | 10,629 | 41.7% | 33.3% | |
| 52.38% | 21 | 6.2 | 840 | 12,488 | 42.9% | 57.1% | |
| 42.86% | 21 | 1.1 | 744 | 12,955 | 40.0% | 45.5% | |
| 31.58% | 19 | 5.9 | 717 | 10,708 | 33.3% | 28.6% | |
| 31.58% | 19 | 1.1 | 693 | 12,643 | 20.0% | 44.4% | |
| 33.33% | 18 | 6.0 | 857 | 12,013 | 30.0% | 37.5% | |
| 61.11% | 18 | 5.9 | 1,100 | 12,451 | 60.0% | 62.5% | |
| 58.82% | 17 | 5.8 | 924 | 12,153 | 63.6% | 50.0% | |
| 58.82% | 17 | 5.9 | 942 | 12,149 | 62.5% | 55.6% | |
| 56.25% | 16 | 6.8 | 925 | 9,842 | 72.7% | 20.0% | |
| 37.50% | 16 | 1.2 | 748 | 13,746 | 80.0% | 18.2% | |
| 62.50% | 16 | 6.1 | 924 | 12,725 | 66.7% | 60.0% | |
| 43.75% | 16 | 6.3 | 784 | 11,643 | 40.0% | 50.0% | |
| 25.00% | 16 | 6.0 | 679 | 11,362 | 33.3% | 20.0% | |
| 43.75% | 16 | 6.7 | 1,034 | 12,146 | 60.0% | 16.7% | |
| 50.00% | 14 | 6.2 | 943 | 12,505 | 44.4% | 60.0% | |
| 42.86% | 14 | 6.2 | 775 | 12,609 | 80.0% | 22.2% | |
| 57.14% | 14 | 1.4 | 805 | 14,325 | 33.3% | 75.0% | |
| 64.29% | 14 | 6.7 | 981 | 12,489 | 62.5% | 66.7% | |
| 30.77% | 13 | 4.8 | 743 | 11,517 | 28.6% | 33.3% | |
| 61.54% | 13 | 2.1 | 1,018 | 13,300 | 66.7% | 57.1% | |
| 38.46% | 13 | 6.0 | 812 | 12,679 | 33.3% | 42.9% | |
| 23.08% | 13 | 1.0 | 701 | 12,712 | 33.3% | 14.3% | |
| 53.85% | 13 | 5.8 | 777 | 11,480 | 57.1% | 50.0% | |
| 16.67% | 12 | 6.5 | 721 | 11,080 | 0.0% | 28.6% | |
| 25.00% | 12 | 6.0 | 741 | 10,931 | 0.0% | 37.5% | |
| 45.45% | 11 | 1.3 | 604 | 10,864 | 37.5% | 66.7% | |
| 70.00% | 10 | 1.3 | 949 | 17,314 | 100.0% | 66.7% | |
| 60.00% | 10 | 1.1 | 872 | 15,454 | 50.0% | 62.5% | |
| 50.00% | 10 | 6.0 | 1,075 | 14,773 | 66.7% | 42.9% | |
| 70.00% | 10 | 2.5 | 874 | 13,055 | 75.0% | 66.7% | |
| 33.33% | 9 | 2.4 | 744 | 12,428 | 60.0% | 0.0% | |
| 77.78% | 9 | 6.3 | 1,011 | 12,189 | 60.0% | 100.0% | |
| 66.67% | 9 | 5.9 | 951 | 12,117 | 75.0% | 60.0% | |
| 33.33% | 9 | 5.2 | 720 | 13,159 | 50.0% | 28.6% | |
| 22.22% | 9 | 0.9 | 803 | 14,401 | 0.0% | 33.3% | |
| 55.56% | 9 | 0.9 | 752 | 15,452 | 50.0% | 60.0% | |
| 44.44% | 9 | 2.8 | 986 | 11,077 | 25.0% | 60.0% | |
| 37.50% | 8 | 1.1 | 726 | 14,788 | 50.0% | 33.3% | |
| 75.00% | 8 | 6.5 | 1,310 | 15,063 | 60.0% | 100.0% | |
| 37.50% | 8 | 6.8 | 914 | 12,781 | 33.3% | 40.0% | |
| 25.00% | 8 | 5.3 | 704 | 12,058 | 0.0% | 50.0% | |
| 37.50% | 8 | 0.7 | 841 | 10,748 | 40.0% | 33.3% | |
| 71.43% | 7 | 2.5 | 669 | 13,882 | 80.0% | 50.0% | |
| 71.43% | 7 | 1.4 | 721 | 12,334 | 75.0% | 66.7% | |
| 71.43% | 7 | 3.0 | 794 | 12,565 | 0.0% | 100.0% | |
| 71.43% | 7 | 1.3 | 886 | 12,567 | 80.0% | 50.0% | |
| 28.57% | 7 | 1.1 | 728 | 13,512 | 50.0% | 20.0% | |
| 57.14% | 7 | 3.7 | 779 | 11,912 | 0.0% | 100.0% | |
| 33.33% | 6 | 6.3 | 1,059 | 12,990 | 0.0% | 50.0% | |
| 33.33% | 6 | 1.2 | 900 | 15,906 | 25.0% | 50.0% | |
| 50.00% | 6 | 0.7 | 603 | 12,258 | 66.7% | 33.3% | |
| 66.67% | 6 | 7.4 | 1,214 | 15,143 | 100.0% | 33.3% | |
| 50.00% | 6 | 5.7 | 1,068 | 14,061 | 50.0% | 50.0% | |
| 83.33% | 6 | 1.2 | 840 | 13,798 | 50.0% | 100.0% | |
| 20.00% | 5 | 1.2 | 706 | 14,982 | 0.0% | 20.0% | |
| 40.00% | 5 | 1.1 | 931 | 15,946 | 100.0% | 25.0% | |
| 0.00% | 5 | 2.9 | 665 | 9,745 | 0.0% | 0.0% | |
| 60.00% | 5 | 0.9 | 792 | 10,169 | 66.7% | 50.0% | |
| 20.00% | 5 | 3.9 | 660 | 10,305 | 50.0% | 0.0% | |
| 20.00% | 5 | 2.2 | 880 | 11,986 | 0.0% | 100.0% | |
| 20.00% | 5 | 0.8 | 996 | 9,951 | 0.0% | 50.0% | |
| 80.00% | 5 | 5.1 | 772 | 11,535 | 66.7% | 100.0% | |
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Qiyana vs Karthus - Frequently Asked Questions
How does Qiyana do against Karthus in League of Legends?
Karthus wins the Qiyana vs Karthus matchup with a 80.0% win rate compared to Qiyana's 20.0%, a 60.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.9.
How does Qiyana do against Karthus in the early game?
In the early game, Karthus has the advantage against Qiyana with a 100.0% win rate versus 0.0%. Karthus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Qiyana do against Karthus in the late game?
In the late game, Qiyana takes over the Qiyana vs Karthus matchup with a 100.0% win rate compared to 0.0%. Qiyana scales better into team fights and objective contests after 25 minutes.
Who wins the Qiyana vs Karthus matchup?
Karthus wins the matchup against Qiyana with a 80.0% win rate in League of Legends patch 26.9. The 60.0 percentage point advantage means Karthus is significantly favored in this lane matchup based on 5 games analyzed.
What is the best Qiyana build against Karthus?
The best Qiyana build against Karthus includes Voltaic Cyclosword, Axiom Arc, Edge of Night with Slightly Magical Footwear. Check the matchup breakdown above for the full item path and build order.
What are the best Qiyana runes against Karthus?
The best Qiyana runes against Karthus use the Domination primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Qiyana vs Karthus matchup. See the full rune breakdown in the matchup comparison above.
Does Qiyana counter Karthus?
No, Qiyana struggles against Karthus with only a 20.0% win rate. Karthus has the advantage in this matchup. Qiyana players should focus on safe farming and avoiding extended trades to minimize Karthus's lead.
How do I play Qiyana against Karthus?
When playing Qiyana against Karthus, play cautiously and avoid Karthus's power spikes. Focus on safe farming — you outscale Karthus in the late game. Use the matchup-specific build and runes above to optimize your chances.