Senna - League of Legends Champion
Win Rate
50.0%
Pick Rate
6.3%

Sennavs Nasus

BSupportMarksman
Patch26.10
Matches683,599
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 17, 2026
MethodologyData Methodology

Senna vs Nasus is a decisive matchup in LoL patch 26.10. Nasus wins with a 80.0% win rate (+60.0%) over Senna based on 5 games. Nasus wins the early laning phase while Senna scales better into the late game. Below you'll find the best Senna build, runes, laning stats, and strategies for the Senna vs Nasus matchup.

Senna Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Senna performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Nasus - 20.0% win rateNasus(20.0%)
Senna - 20.0% win rate in this matchup
Senna
20.0% WR
VS
Nasus vs Senna matchup - 80.0% win rate
Nasus
80.0% WR

Who Wins the Senna vs Nasus Matchup?

Nasus wins the Senna vs Nasus matchup
Winner
Nasus
Matches: 5
20.0%
Win Rate
80.0%
6.5
CS / min
6.3
1,081
DMG / min
377
8,434
Gold / game
7,683
438
Heal / min
558
337
DMG Mitigated / min
1,751
1.6
CC / min
0.6
0.0%
Early Game WR
100.0%
50.0%
Late Game WR
50.0%

Senna vs Nasus Matchup Summary

The Senna vs Nasus matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Nasus wins with a 80.0% win rate compared to Senna's 20.0%, giving Nasus a 60.0 percentage point advantage. Game phase dynamics play a critical role here: Nasus controls the early laning stage, but Senna outscales as the game goes longer. The matchup shifts dramatically depending on game length — Nasus needs to press advantages before Senna reaches their power spikes, while Senna should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Nasus leads by 1,533 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Nasus has a strong advantage in this matchup. Senna players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Nasus overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Senna vs Nasus Laning Phase Breakdown

Senna wins the laning phase against Nasus in League of Legends

Senna is favored during the laning phase against Nasus, winning 4 out of 5 key stat categories. Senna holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
6.5Senna
6.3Nasus
Senna and Nasus farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
1,081Senna
377Nasus
Senna heavily out-damages Nasus by 704 DMG/min, dominating both short trades and all-in fights. Nasus should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Senna's sustained damage advantage take over.
Economy
8,434Senna
7,683Nasus
Senna earns 751 more gold per game than Nasus, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Senna slightly faster item completions.
Utility
1.6Senna
0.6Nasus
Senna brings significantly more crowd control than Nasus, with 0.9 more seconds of CC per minute. This large utility gap makes Senna far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Nasus should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
776Senna
2,309Nasus
Nasus vastly out-sustains Senna, healing and mitigating 1,533 more damage per minute. This massive durability gap means Nasus can absorb significant punishment and remain in lane while Senna is forced to recall. Building grievous wounds early is essential for Senna, and focusing on burst trade patterns rather than sustained fights is critical.

Best Senna Build Against Nasus

Berserker's Greaves is the optimal boots choice against Nasus, providing the mobility and stats Senna needs most in this matchup. The top-performing core items for Senna against Nasus are Runaan's Hurricane, Mortal Reminder and Yun Tal Wildarrows. This combination gives Senna an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Senna vs Nasus matchup.

Early Game vs Late Game

Early Game
Nasus
100.0%
+100.0% advantage
Senna early game win rateSenna0.0%
Nasus early game win rateNasus100.0%
Late Game
Senna
50.0%
+0.0% advantage
Senna late game win rateSenna50.0%
Nasus late game win rateNasus50.0%

Nasus dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Senna. This lopsided early game means Nasus can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Late game (25+ minutes) is equally balanced, with Senna at 50.0% win rate — only 0.0 points ahead of Nasus. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.

The power dynamics shift as the game progresses — Nasus has the edge early, but Senna gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Senna Runes Against Nasus

Sorcery rune tree - Senna primary runes vs NasusSorcery
Deathfire Touch - best Senna rune vs NasusManaflow Band - best Senna rune vs NasusAbsolute Focus - best Senna rune vs NasusGathering Storm - best Senna rune vs Nasus
Precision rune tree - Senna secondary runes vs NasusPrecision
Presence of Mind - best Senna rune vs NasusLegend: Alacrity - best Senna rune vs Nasus
100.0% WR

The Sorcery and Precision rune setup gives Senna the best tools to compete against Nasus in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Senna matchup data for League of Legends patch 26.10. The table below shows Senna's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Senna build, runes, laning stats, and early vs late game analysis for that specific matchup.

Senna matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
49.43%4351.757410,09442.3%54.2%
49.32%3656.291113,47046.3%51.4%
53.30%3641.66409,98552.4%54.2%
51.08%3231.855110,31239.7%58.9%
53.48%3161.561010,11751.4%55.1%
53.09%3075.372611,65650.0%55.5%
49.81%2651.559510,30048.0%51.4%
50.19%2636.074812,84354.0%47.4%
47.30%2412.363811,30843.7%49.4%
47.37%2091.662010,10646.0%48.4%
45.26%1901.764511,00550.7%42.1%
48.31%1781.56089,48149.0%47.6%
47.67%1721.661610,63847.8%47.6%
45.03%1711.55859,80352.9%37.2%
48.48%1651.56329,43949.4%47.4%
44.24%1656.179612,87043.6%44.8%
46.67%1655.977312,76652.3%43.0%
51.88%1601.55769,90446.5%56.2%
55.70%1585.681413,04347.5%60.8%
51.68%1495.377212,58149.3%53.8%
52.11%1421.552610,13858.1%47.5%
50.71%1402.267211,01360.0%46.3%
55.07%1381.661110,16353.1%56.8%
50.00%1341.858611,22054.4%47.7%
53.79%1321.661910,09656.7%51.4%
57.69%1301.760410,65052.1%61.0%
55.91%1271.568910,24048.5%63.9%
60.00%1251.56379,94463.1%56.7%
50.81%1241.67379,39556.9%44.1%
55.26%1141.860910,60947.7%60.0%
52.63%1141.45909,61455.2%50.0%
53.33%906.084113,14848.8%57.5%
54.32%815.984813,22265.8%44.2%
58.02%812.668811,23456.7%58.8%
50.65%771.56149,84057.5%43.2%
44.74%761.569510,96650.0%41.7%
49.30%716.184012,67953.3%46.3%
50.70%711.55709,81059.4%43.6%
41.18%686.079713,29950.0%34.2%
56.06%666.586213,53266.7%47.2%
44.44%631.765610,20357.6%30.0%
54.84%621.565110,42061.5%50.0%
49.15%595.055711,06253.6%45.2%
62.71%591.667610,87953.9%69.7%
47.27%552.461310,63236.8%52.8%
48.15%545.763411,13937.0%59.3%
43.40%535.882911,68048.1%38.5%
58.00%501.960710,94442.1%67.7%
46.94%491.863611,54337.5%51.5%
60.87%466.788312,91559.1%62.5%
67.44%431.666411,21580.0%60.7%
62.50%403.467111,16156.3%66.7%
50.00%406.386012,66736.8%61.9%
44.74%382.467410,65253.3%39.1%
55.26%385.785113,48333.3%65.4%
45.95%375.476611,80840.0%50.0%
38.89%366.582011,87640.0%37.5%
35.29%342.666311,41930.0%37.5%
63.64%331.473310,01178.6%52.6%
53.13%322.364310,53054.5%52.4%
54.84%315.169611,82730.8%72.2%
51.61%311.56129,67062.5%40.0%
42.86%285.275612,84854.5%35.3%
46.43%286.289513,80650.0%43.8%
42.31%265.675012,72820.0%56.3%
32.00%256.283011,04925.0%44.4%
60.00%255.276211,90871.4%45.5%
38.10%212.866211,76942.9%35.7%
57.89%192.556211,26750.0%61.5%
57.89%192.782111,33644.4%70.0%
47.06%173.182310,59228.6%60.0%
47.06%171.95739,96944.4%50.0%
37.50%161.955810,40742.9%33.3%
56.25%161.659710,16071.4%44.4%
56.25%161.86059,17422.2%100.0%
60.00%151.855910,63342.9%75.0%
64.29%145.682010,51470.0%50.0%
50.00%145.786112,53833.3%62.5%
42.86%143.076012,798100.0%33.3%
35.71%141.967311,02260.0%22.2%
53.85%133.163412,16166.7%50.0%
58.33%122.467412,63975.0%50.0%
33.33%121.55529,41540.0%28.6%
45.45%116.385711,16633.3%50.0%
36.36%115.091111,06740.0%33.3%
50.00%104.06858,77257.1%33.3%
70.00%104.374911,44775.0%66.7%
77.78%92.17359,69975.0%80.0%
33.33%96.366113,78333.3%33.3%
44.44%92.171413,0550.0%44.4%
50.00%84.774112,0060.0%66.7%
37.50%84.978810,16160.0%0.0%
37.50%82.582311,07133.3%40.0%
75.00%81.678912,774100.0%66.7%
62.50%85.076014,570100.0%50.0%
75.00%81.25948,52480.0%66.7%
62.50%84.473713,100100.0%50.0%
50.00%81.47689,20040.0%66.7%
50.00%83.688514,31433.3%60.0%
28.57%74.471711,8360.0%28.6%
57.14%72.767410,48360.0%50.0%
42.86%71.66059,54050.0%33.3%
28.57%74.05868,77825.0%33.3%
42.86%73.162612,48950.0%40.0%
57.14%75.383012,923100.0%50.0%
28.57%74.067011,13066.7%0.0%
57.14%72.491113,47950.0%60.0%
50.00%64.987812,0670.0%60.0%
33.33%65.36549,85933.3%33.3%
40.00%55.276911,05250.0%33.3%
40.00%54.896214,8880.0%50.0%
60.00%53.783013,253100.0%50.0%
60.00%54.762811,4450.0%75.0%
80.00%52.890913,037100.0%75.0%
20.00%56.51,0818,4340.0%50.0%
40.00%54.876211,9830.0%66.7%
20.00%51.45177,98433.3%0.0%
20.00%51.74248,39633.3%0.0%
40.00%56.08499,67133.3%50.0%

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Senna vs Nasus - Frequently Asked Questions

How does Senna do against Nasus in League of Legends?

Nasus wins the Senna vs Nasus matchup with a 80.0% win rate compared to Senna's 20.0%, a 60.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.10.

How does Senna do against Nasus in the early game?

In the early game, Nasus has the advantage against Senna with a 100.0% win rate versus 0.0%. Nasus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Senna do against Nasus in the late game?

In the late game, Senna takes over the Senna vs Nasus matchup with a 50.0% win rate compared to 50.0%. Senna scales better into team fights and objective contests after 25 minutes.

Who wins the Senna vs Nasus matchup?

Nasus wins the matchup against Senna with a 80.0% win rate in League of Legends patch 26.10. The 60.0 percentage point advantage means Nasus is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Senna build against Nasus?

The best Senna build against Nasus includes Runaan's Hurricane, Mortal Reminder, Yun Tal Wildarrows with Berserker's Greaves. Check the matchup breakdown above for the full item path and build order.

What are the best Senna runes against Nasus?

The best Senna runes against Nasus use the Sorcery primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Senna vs Nasus matchup. See the full rune breakdown in the matchup comparison above.

Does Senna counter Nasus?

No, Senna struggles against Nasus with only a 20.0% win rate. Nasus has the advantage in this matchup. Senna players should focus on safe farming and avoiding extended trades to minimize Nasus's lead.

How do I play Senna against Nasus?

When playing Senna against Nasus, play cautiously and avoid Nasus's power spikes. Focus on safe farming — you outscale Nasus in the late game. Use the matchup-specific build and runes above to optimize your chances.