
- Win Rate
- 49.9%
- Pick Rate
- 3.6%
- Ban Rate
- 1.8%
Senna vs Seraphine
- Patch
- 26.22
- Games
- 2,252
- Lane
- All Lanes
- Tier
- All Tiers
- Last Updated
- Nov 6, 2026 UTC
- Author
- Dakota Chinnick
- Methodology
- Data Methodology
Senna vs Seraphine is a decisive matchup in LoL patch 26.22. Seraphine wins with a 53.0% win rate (+6.1%) over Senna based on 115 games. Senna wins the early laning phase while Seraphine scales better into the late game. Below you'll find the best Senna build, runes, laning stats, and strategies for the Senna vs Seraphine matchup.
Senna Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Senna performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.


Who wins Senna vs Seraphine?
Senna wins 47.7% of these games. With this many games the true rate is most likely between 38.7% and 57.0% (95% range).
- Expected
- 48.6% From both champions' overall Support win rates
- Matchup effect
- −0.9 pts Observed minus expected
- Sample
- 111 games Lane: Support
- vs patch 26.21
- −0.2 pts Within normal patch-to-patch noise
Lane: Support · Ranked Solo/Duo & Flex · North America server · All ranks · Patch 26.22 · Nov 4 – Nov 6
Key takeaways
- Current data slightly favors Seraphine, but the sample is too limited for a strong conclusion: Senna wins 47.7% of 111 games (95% range 38.7–57.0%).
- Both champions' overall Support win rates predict 48.6% for Senna; the result is within the margin of error of that, so this matchup mostly reflects the two champions' general strength.
- Senna usually wins the lane: 259 gold ahead of Seraphine at 15 minutes on average (109 games with a 15-minute snapshot).
- Senna players pick Hexoptics C44 far more often against Seraphine: 9.7% of their other Support games, 17.1% here.
How we calculate this
Games: ranked Solo/Duo and Flex games on the North America server from the patch shown. Remakes (games under 5 minutes) are excluded.
A game only counts when Senna and Seraphine played the same position on opposite teams, so roaming, lane swaps within a team or a champion merely being in the same game never count as this matchup.
The 95% range is a Wilson score interval. Confidence comes from how wide that range is: within ±3 points is very high, ±5 high, ±8 moderate, anything wider low. Below 20 games a matchup is not classified at all.
Expected win rate combines both champions’ win rates in this lane (same games and filters) with the log5 formula: E = A(1−B) / (A(1−B) + B(1−A)). Matchup effect = observed − expected.
"What changes" compares Senna's choices in this matchup with the same champion's other games in the same lane, and lists a change only when it is at least 3 points and statistically significant (two-proportion z-test, |z| ≥ 2, 20+ games).
Results are not split by rank: the sample per rank is too small for honest per-rank matchup numbers.
Senna vs Seraphine Laning Stats
At 15 minutes
Whole-game averages
Senna vs Seraphine Win Rate by Game Length
Senna's win rate against Seraphine by game length. The dot is the win rate, the bar its 95% range and the dashed line the champion's usual win rate at that length. Lengths with fewer than 25 games are left blank.
No game length stands out: Senna's results against Seraphine in short and long games are within the margin of error of each other.
Senna vs Seraphine Power Spikes
Who is ahead at each stage, measured from these games. A stage reads "Even" when the difference is inside the margin of error, and "Insufficient data" when there are too few games to tell.
- Lane (15 min)SennaSenna gold at 15: +259
- First itemSeraphineSenna: 13.6 min · Seraphine: 12.1 min
- Games under 20 minInsufficient data
- 20–30 min gamesEvenSenna wins 52.8% of 53 games
- 30+ min gamesEvenSenna wins 39.6% of 53 games
What Senna Changes Against Seraphine
Choices Senna players make noticeably more or less often in this matchup than in their other Support games.
Hexoptics C44ItemUsually9.7%vs Seraphine17.1%+7.4 pts
TriumphRuneUsually2.8%vs Seraphine7.2%+4.5 pts
Ability Haste (offense)Stat shardUsually1.9%vs Seraphine6.3%+4.4 pts
Usually1.5%vs Seraphine5.4%+3.9 pts
Best Senna Build vs Seraphine
Usual Senna build (Support)
59.6% win rate · 260 games
Against Seraphine
Not enough matchup-specific build data: only 14 of 50 Senna games against Seraphine carried a complete build, which is too few to recommend an item path from. Use Senna's standard build instead.
- Senna usually completes Black Cleaver first, at 13.6 min (median of 50 games).
- Seraphine usually completes Echoes of Helia first, at 12.1 min (median of 50 games).
- Skill priority: Q > W > E — the same as usual.
Builds are ranked by the lower edge of their win rate range, not the raw win rate, so a build seen in a handful of wins never outranks a proven one.
Best Senna Runes vs Seraphine
Plan your Senna draft in Draft Lab
Draft Lab lays out both teams lane by lane with live matchup win rates, damage profiles and game-phase lean, and suggests picks and bans from current meta data.
- Full 5v5 draft board
- Lane matchup win rates
- Pick and ban suggestions

Senna matchup data for League of Legends patch 26.22. The table below shows Senna's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Senna build, runes, laning stats, and early vs late game analysis for that specific matchup.
Other Senna Matchups
Hardest for Senna
Easiest for Senna
Win rate and games for each matchup. Lists are ranked by the edge of the 95% range so small samples cannot top them; matchups with at least 50 games only.
Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.
Senna vs Seraphine FAQ - Patch 26.22
Who wins Senna vs Seraphine?
Current data slightly favors Seraphine, but the sample is too limited for a strong conclusion: Senna wins 47.7% of 111 games (95% range 38.7–57.0%).
What is Senna's win rate against Seraphine?
Senna wins 47.7% of 111 Support games against Seraphine on patch 26.22 (95% range 38.7–57.0%). Based on both champions' overall Support win rates, 48.6% would be expected.
Does Senna counter Seraphine?
Not clearly. Senna wins 47.7% of 111 games against Seraphine, and the 95% range (38.7–57.0%) includes 50%, so neither champion reliably counters the other on current data.
Who wins lane, Senna or Seraphine?
Senna usually wins the lane: 259 gold ahead of Seraphine at 15 minutes on average (109 games with a 15-minute snapshot).
Does Senna outscale Seraphine?
There are too few games of each length to tell yet.
When is Seraphine strongest against Senna?
Seraphine is measurably ahead in: First item.
What should Senna build against Seraphine?
There are not enough games for a matchup-specific core, so use Senna's usual Support core: Rapid Firecannon, Statikk Shiv, Black Cleaver. The biggest change against Seraphine: Hexoptics C44 (9.7% usually, 17.1% here).
What runes should Senna use against Seraphine?
Deathfire Touch with Sorcery and Inspiration — 50.0% over 20 games against Seraphine. The biggest change against Seraphine: Triumph (2.8% usually, 7.2% here).
