Senna - League of Legends Champion
Win Rate
49.3%
Pick Rate
5.6%

Sennavs Seraphine

DSupportMarksman
Patch26.14
Matches491,560
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 23, 2026
MethodologyData Methodology

Senna vs Seraphine is a moderate matchup in LoL patch 26.14. Seraphine wins with a 51.5% win rate (+3.0%) over Senna based on 330 games. Senna wins the early laning phase while Seraphine scales better into the late game. Below you'll find the best Senna build, runes, laning stats, and strategies for the Senna vs Seraphine matchup.

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Senna Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Senna performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Senna - 48.5% win rate in this matchup
Senna
48.5% WR
VS
Seraphine vs Senna matchup - 51.5% win rate
Seraphine
51.5% WR

Who Wins the Senna vs Seraphine Matchup?

Seraphine wins the Senna vs Seraphine matchup
Winner
Seraphine
Matches: 330
48.5%
Win Rate
51.5%
2.0
CS / min
1.9
636
DMG / min
532
10,673
Gold / game
9,620
430
Heal / min
269
348
DMG Mitigated / min
385
1.2
CC / min
1.2
50.4%
Early Game WR
49.6%
47.3%
Late Game WR
52.7%

Senna vs Seraphine Matchup Summary

The Senna vs Seraphine matchup is a moderate matchup in League of Legends ranked play. Based on 330 recent matches analyzed, Seraphine wins with a 51.5% win rate compared to Senna's 48.5%, giving Seraphine a 3.0 percentage point advantage. Game phase dynamics play a critical role here: Senna controls the early laning stage, but Seraphine outscales as the game goes longer. The matchup shifts dramatically depending on game length — Senna needs to press advantages before Seraphine reaches their power spikes, while Seraphine should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in damage output, where Senna leads by 104 DMG/min — a difference that heavily influences the outcome of trades and skirmishes. While Seraphine is slightly favored, Senna can absolutely win this lane through smart trading patterns and wave management. Focus on playing around your cooldowns, conceding CS only when necessary, and capitalizing on Seraphine's mistakes. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Senna vs Seraphine Laning Phase Breakdown

Senna wins the laning phase against Seraphine in League of Legends

Senna is favored during the laning phase against Seraphine, winning 5 out of 5 key stat categories. Senna holds advantages in farming, damage, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
2.0Senna
1.9Seraphine
Senna and Seraphine farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
636Senna
532Seraphine
Senna heavily out-damages Seraphine by 104 DMG/min, dominating both short trades and all-in fights. Seraphine should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Senna's sustained damage advantage take over.
Economy
10,673Senna
9,620Seraphine
Senna generates a commanding 1,054 more gold per game than Seraphine. This substantial economic advantage means Senna consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Seraphine should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.2Senna
1.2Seraphine
Both Senna and Seraphine provide similar amounts of crowd control (0.0s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
778Senna
654Seraphine
Senna heals and mitigates 124 more damage per minute than Seraphine, providing moderate extra durability. This sustain edge allows Senna to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Seraphine.

Best Senna Build Against Seraphine

Boots of Swiftness is the optimal boots choice against Seraphine, providing the mobility and stats Senna needs most in this matchup. The top-performing core items for Senna against Seraphine are Echoes of Helia, Statikk Shiv and Black Cleaver. This combination gives Senna an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 3 games — well above average and making it the top item path against Seraphine. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Senna vs Seraphine matchup.

Early Game vs Late Game

Early Game
Senna
50.4%
+0.8% advantage
Senna early game win rateSenna50.4%
Seraphine early game win rateSeraphine49.6%
Late Game
Seraphine
52.7%
+5.4% advantage
Senna late game win rateSenna47.3%
Seraphine late game win rateSeraphine52.7%

The early game (first 15 minutes) is a toss-up between Senna and Seraphine, with Senna holding a razor-thin 50.4% win rate edge (+0.8%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Seraphine is far superior in the late game (25+ minutes), boasting a 52.7% win rate — 5.4 points above Senna. Extended games heavily favor Seraphine, whose kit and scaling make them a dominant force in team fights and objective control.

The power dynamics shift as the game progresses — Senna has the edge early, but Seraphine gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Senna Runes Against Seraphine

Sorcery rune tree - Senna primary runes vs SeraphineSorcery
Deathfire Touch - best Senna rune vs SeraphineManaflow Band - best Senna rune vs SeraphineCelerity - best Senna rune vs SeraphineGathering Storm - best Senna rune vs Seraphine
Inspiration rune tree - Senna secondary runes vs SeraphineInspiration
Magical Footwear - best Senna rune vs SeraphineJack Of All Trades - best Senna rune vs Seraphine
61.9% WR

The Sorcery and Inspiration rune setup gives Senna the best tools to compete against Seraphine in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Senna matchup data for League of Legends patch 26.14. The table below shows Senna's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Senna build, runes, laning stats, and early vs late game analysis for that specific matchup.

Senna matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
48.48%3302.063610,67350.4%47.3%
46.55%2322.053910,24144.3%47.9%
47.98%2235.473212,24452.4%45.3%
48.83%2135.876512,68743.0%52.2%
45.00%1801.75939,97351.4%40.9%
46.43%1681.75979,66644.0%48.4%
44.24%1651.761510,06246.4%42.7%
48.59%1421.962410,77050.0%47.8%
46.76%1395.676812,54042.9%48.9%
45.26%1371.765910,90942.5%46.7%
49.22%1285.171711,53152.7%46.6%
53.33%1201.862311,31556.1%51.9%
48.15%1085.777511,93344.7%50.8%
50.94%1061.65769,46246.0%55.4%
50.49%1032.571110,55352.4%49.2%
46.60%1032.466310,74837.5%52.4%
54.37%1031.663610,35565.0%47.6%
48.96%963.066311,12642.1%53.5%
59.34%915.781212,73352.5%64.7%
53.33%901.864710,53051.4%54.5%
46.59%886.071311,62056.8%36.4%
58.33%841.779211,09365.5%54.5%
50.60%831.65869,47556.8%43.6%
46.91%815.885112,52732.4%57.5%
42.86%772.062010,00448.4%39.1%
38.96%771.858910,38952.0%32.7%
52.05%735.672912,08848.3%54.5%
61.97%711.866310,24466.7%58.5%
48.53%681.865410,59566.7%36.6%
54.41%681.767010,73954.2%54.5%
59.70%675.986914,14261.1%59.2%
50.75%671.672410,48454.5%48.9%
52.31%655.680911,96256.5%50.0%
60.94%645.984912,09861.3%60.6%
38.10%631.670610,37734.8%40.0%
31.58%572.157710,19928.0%34.4%
49.12%575.882012,08845.2%53.9%
54.39%571.865610,08946.7%63.0%
60.00%551.65329,13366.7%52.0%
35.19%545.580311,80943.5%29.0%
52.94%511.66929,69665.2%42.9%
46.00%502.861911,60038.5%48.6%
40.82%491.871810,55540.9%40.7%
51.22%411.556810,17538.5%57.1%
48.72%394.773313,29645.5%50.0%
58.97%394.162811,11852.9%63.6%
58.97%391.77329,91363.2%55.0%
57.89%385.981613,62050.0%61.5%
60.61%336.183312,99250.0%70.6%
43.75%321.761710,18430.8%52.6%
48.39%312.165511,29255.6%45.5%
26.67%301.85958,58640.0%13.3%
62.96%275.889312,79558.3%66.7%
62.96%275.866612,06254.5%68.8%
61.54%261.55939,46261.5%61.5%
50.00%246.280514,30662.5%43.8%
45.83%241.862710,63240.0%50.0%
40.00%202.16359,59130.8%57.1%
60.00%205.885011,30958.3%62.5%
61.11%181.46999,36472.7%42.9%
55.56%183.079411,19777.8%33.3%
38.89%185.765311,75233.3%44.4%
61.11%183.472210,54650.0%66.7%
44.44%185.980012,25644.4%44.4%
52.94%171.468011,55666.7%45.5%
47.06%175.990113,68125.0%53.9%
47.06%171.960910,38812.5%77.8%
66.67%152.071510,82883.3%55.6%
57.14%146.285814,16833.3%63.6%
46.15%135.777512,41740.0%50.0%
58.33%122.792412,52640.0%71.4%
63.64%112.051411,50875.0%57.1%
63.64%112.266510,18340.0%83.3%
40.00%105.964210,25966.7%0.0%
40.00%103.065311,81720.0%60.0%
60.00%103.669011,690100.0%42.9%
50.00%101.556711,6330.0%55.6%
50.00%103.586411,19350.0%50.0%
70.00%105.66319,67260.0%80.0%
37.50%86.384712,44525.0%50.0%
12.50%81.85127,2120.0%25.0%
37.50%82.77529,8030.0%75.0%
42.86%72.872111,5540.0%60.0%
57.14%75.286212,97333.3%75.0%
71.43%73.875914,755100.0%66.7%
57.14%72.31,05110,41433.3%75.0%
42.86%74.87819,2240.0%75.0%
50.00%65.86827,09040.0%100.0%
50.00%62.860412,3790.0%50.0%
66.67%62.581613,453100.0%60.0%
20.00%54.067410,63933.3%0.0%
40.00%53.985110,72033.3%50.0%
20.00%54.874411,7310.0%25.0%
60.00%54.56578,05750.0%100.0%
80.00%55.576811,618100.0%75.0%
60.00%56.57249,87733.3%100.0%
60.00%55.571911,350100.0%50.0%
40.00%53.96659,64166.7%0.0%
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Senna vs Seraphine - Frequently Asked Questions

How does Senna do against Seraphine in League of Legends?

Seraphine wins the Senna vs Seraphine matchup with a 51.5% win rate compared to Senna's 48.5%, a 3.0 percentage point difference. This data is based on 330 recent ranked games in patch 26.14.

How does Senna do against Seraphine in the early game?

In the early game, Senna has the advantage against Seraphine with a 50.4% win rate versus 49.6%. Senna players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Senna do against Seraphine in the late game?

In the late game, Seraphine takes over the Senna vs Seraphine matchup with a 52.7% win rate compared to 47.3%. Seraphine scales better into team fights and objective contests after 25 minutes.

Who wins the Senna vs Seraphine matchup?

Seraphine wins the matchup against Senna with a 51.5% win rate in League of Legends patch 26.14. The 3.0 percentage point advantage means Seraphine is moderately favored in this lane matchup based on 330 games analyzed.

What is the best Senna build against Seraphine?

The best Senna build against Seraphine includes Echoes of Helia, Statikk Shiv, Black Cleaver with Boots of Swiftness. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Senna runes against Seraphine?

The best Senna runes against Seraphine use the Sorcery primary tree with Inspiration secondary. This rune setup achieves a 61.9% win rate in the Senna vs Seraphine matchup. See the full rune breakdown in the matchup comparison above.

Does Senna counter Seraphine?

No, Senna struggles against Seraphine with only a 48.5% win rate. Seraphine has the advantage in this matchup. Senna players should focus on safe farming and avoiding extended trades to minimize Seraphine's lead.

How do I play Senna against Seraphine?

When playing Senna against Seraphine, play cautiously and avoid Seraphine's power spikes. Look for jungle assistance and team-dependent plays since Seraphine has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.