Senna - League of Legends Champion
Win Rate
51.7%
Pick Rate
6.7%

Sennavs Seraphine

SSupportMarksman
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 7, 2026
MethodologyData Methodology

Senna vs Seraphine is a very close matchup in LoL patch 26.11. Seraphine wins with a 50.2% win rate (+0.4%) over Senna based on 478 games. Seraphine wins the early laning phase while Senna scales better into the late game. Below you'll find the best Senna build, runes, laning stats, and strategies for the Senna vs Seraphine matchup.

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Senna Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Senna performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Senna - 49.8% win rate in this matchup
Senna
49.8% WR
VS
Seraphine vs Senna matchup - 50.2% win rate
Seraphine
50.2% WR

Who Wins the Senna vs Seraphine Matchup?

Seraphine wins the Senna vs Seraphine matchup
Winner
Seraphine
Matches: 478
49.8%
Win Rate
50.2%
1.9
CS / min
1.8
600
DMG / min
526
10,125
Gold / game
9,255
462
Heal / min
285
340
DMG Mitigated / min
374
1.3
CC / min
1.2
48.4%
Early Game WR
51.6%
51.0%
Late Game WR
49.0%

Senna vs Seraphine Matchup Summary

The Senna vs Seraphine matchup is essentially a coin-flip matchup in League of Legends ranked play. Based on 478 recent matches analyzed, Seraphine wins with a 50.2% win rate compared to Senna's 49.8%, giving Seraphine a 0.4 percentage point advantage. Game phase dynamics play a critical role here: Seraphine controls the early laning stage, but Senna outscales as the game goes longer. The matchup shifts dramatically depending on game length — Seraphine needs to press advantages before Senna reaches their power spikes, while Senna should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Senna leads by 143 HP/min — a difference that heavily influences the outcome of trades and skirmishes. While Seraphine is slightly favored, Senna can absolutely win this lane through smart trading patterns and wave management. Focus on playing around your cooldowns, conceding CS only when necessary, and capitalizing on Seraphine's mistakes. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Senna vs Seraphine Laning Phase Breakdown

Senna wins the laning phase against Seraphine in League of Legends

Senna is favored during the laning phase against Seraphine, winning 5 out of 5 key stat categories. Senna holds advantages in farming, damage, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
1.9Senna
1.8Seraphine
Senna and Seraphine farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
600Senna
526Seraphine
Senna deals 74 more champion damage per minute than Seraphine. While noticeable in extended trades, this gap can be offset by Seraphine choosing favorable fight windows, such as engaging when Senna's key abilities are on cooldown or trading immediately after dodging a skillshot.
Economy
10,125Senna
9,255Seraphine
Senna generates a commanding 869 more gold per game than Seraphine. This substantial economic advantage means Senna consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Seraphine should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.3Senna
1.2Seraphine
Both Senna and Seraphine provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
802Senna
659Seraphine
Senna heals and mitigates 143 more damage per minute than Seraphine, providing moderate extra durability. This sustain edge allows Senna to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Seraphine.

Best Senna Build Against Seraphine

Boots of Swiftness is the optimal boots choice against Seraphine, providing the mobility and stats Senna needs most in this matchup. The top-performing core items for Senna against Seraphine are Statikk Shiv, Black Cleaver and Hexoptics C44. This combination gives Senna an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 75.0% win rate across 4 games — well above average and making it the top item path against Seraphine. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Senna vs Seraphine matchup.

Early Game vs Late Game

Early Game
Seraphine
51.6%
+3.2% advantage
Senna early game win rateSenna48.4%
Seraphine early game win rateSeraphine51.6%
Late Game
Senna
51.0%
+1.9% advantage
Senna late game win rateSenna51.0%
Seraphine late game win rateSeraphine49.0%

During the early laning phase (first 15 minutes), Seraphine has a meaningful 51.6% win rate, outperforming Senna by 3.2 percentage points. Seraphine players should look to press this advantage through aggressive trades, wave priority, and early jungle coordination.

Late game (25+ minutes) is equally balanced, with Senna at 51.0% win rate — only 1.9 points ahead of Seraphine. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.

The power dynamics shift as the game progresses — Seraphine has the edge early, but Senna gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Senna Runes Against Seraphine

Sorcery rune tree - Senna primary runes vs SeraphineSorcery
Deathfire Touch - best Senna rune vs SeraphineManaflow Band - best Senna rune vs SeraphineCelerity - best Senna rune vs SeraphineGathering Storm - best Senna rune vs Seraphine
Inspiration rune tree - Senna secondary runes vs SeraphineInspiration
Magical Footwear - best Senna rune vs SeraphineJack Of All Trades - best Senna rune vs Seraphine
68.4% WR

The Sorcery primary with Inspiration secondary combination helps Senna maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Seraphine.


Senna matchup data for League of Legends patch 26.11. The table below shows Senna's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Senna build, runes, laning stats, and early vs late game analysis for that specific matchup.

Senna matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
49.79%4781.960010,12548.4%51.0%
52.43%3916.179712,53348.4%56.2%
46.98%3642.054810,60839.5%52.4%
48.42%3491.662910,54949.0%48.0%
48.37%3375.575412,57847.1%49.5%
57.41%3241.663110,72759.7%55.4%
56.72%3056.291713,61461.5%53.5%
47.47%2971.662710,06144.8%50.0%
43.99%2911.665510,02748.1%40.4%
48.42%2856.081512,84951.2%46.3%
54.78%2726.079212,82650.4%57.9%
51.22%2461.666910,98850.0%52.0%
50.21%2372.863011,28545.3%53.5%
59.31%2315.881312,72658.2%60.3%
54.78%2305.676612,74653.3%56.1%
47.74%1991.669610,23542.2%52.3%
44.92%1871.55659,75657.0%36.1%
54.29%1751.663010,66554.0%54.5%
47.13%1571.662510,80255.9%41.8%
47.30%1481.65929,98050.0%44.3%
50.34%1451.55679,57948.6%52.0%
56.64%1431.783210,66665.2%49.4%
60.84%1436.180113,09759.7%61.8%
52.11%1422.158810,86046.1%55.6%
57.55%1391.558910,21856.9%58.1%
59.42%1381.566510,31160.9%58.1%
43.70%1351.858010,86638.1%46.2%
54.40%1251.46479,76056.7%52.3%
59.35%1231.566610,24255.0%63.5%
55.37%1212.379511,32252.8%57.4%
53.33%1201.869710,47044.9%59.1%
38.98%1182.558210,15332.1%44.6%
57.39%1156.085912,79566.0%50.8%
56.25%1122.765611,46458.3%54.7%
49.53%1075.573211,86550.0%49.1%
56.60%1061.561410,59463.6%51.6%
50.48%1055.976412,78847.7%52.5%
47.96%981.564610,27358.8%36.2%
49.48%971.673710,10051.9%46.5%
52.63%955.982212,59348.9%56.0%
43.68%871.562810,13445.5%41.9%
60.92%875.882512,77061.0%60.9%
47.62%845.887913,30047.2%47.9%
50.00%766.176712,54553.9%46.0%
56.34%711.664310,67355.6%56.8%
53.62%696.186213,25554.8%52.6%
55.22%671.771310,55956.3%54.3%
41.27%631.658210,00632.4%51.7%
40.98%615.979512,54952.0%33.3%
56.14%576.276913,36750.0%60.0%
39.29%566.484312,19240.6%37.5%
53.70%541.571010,49847.6%57.6%
42.31%522.556210,81438.9%44.1%
36.17%474.569212,29931.6%39.3%
57.78%451.75939,92565.2%50.0%
68.18%441.773011,13881.3%60.7%
54.55%446.091013,57950.0%57.1%
50.00%445.676812,22952.6%48.0%
55.81%431.871310,57870.6%46.1%
48.65%375.469212,02433.3%59.1%
52.78%362.071510,73861.1%44.4%
37.14%352.15849,96329.4%44.4%
54.55%333.970812,05214.3%65.4%
48.28%296.195313,54861.5%37.5%
67.86%285.477412,98083.3%56.3%
37.04%271.85929,93950.0%23.1%
56.00%252.364211,17140.0%66.7%
52.17%236.286012,42638.5%70.0%
52.38%216.190314,07744.4%58.3%
61.90%211.95968,42871.4%42.9%
40.00%201.566410,93657.1%30.8%
52.63%192.166110,75344.4%60.0%
52.94%172.883712,69557.1%50.0%
23.53%176.288414,68320.0%25.0%
35.29%175.070612,60114.3%50.0%
43.75%162.365011,94133.3%50.0%
53.33%152.14989,50237.5%71.4%
57.14%142.877211,70271.4%42.9%
42.86%141.75598,86612.5%83.3%
42.86%145.986914,09975.0%30.0%
63.64%116.888712,05550.0%100.0%
45.45%113.772011,78820.0%66.7%
72.73%114.262112,093100.0%62.5%
50.00%103.084610,73050.0%50.0%
60.00%101.86159,07050.0%66.7%
50.00%103.794911,81460.0%40.0%
60.00%102.080412,39150.0%62.5%
50.00%101.76249,60125.0%66.7%
30.00%101.963411,3180.0%42.9%
40.00%105.774810,96740.0%40.0%
50.00%101.657110,36233.3%57.1%
70.00%103.066612,29650.0%83.3%
60.00%105.683813,4100.0%66.7%
66.67%95.956111,32766.7%66.7%
33.33%94.384213,14625.0%40.0%
100.00%92.877610,063100.0%100.0%
44.44%91.86659,94975.0%20.0%
25.00%84.56159,76033.3%20.0%
62.50%82.977911,74950.0%75.0%
25.00%83.55048,14150.0%0.0%
14.29%71.56258,8820.0%33.3%
42.86%74.864610,22233.3%50.0%
42.86%74.91,19511,30533.3%50.0%
28.57%73.958311,6790.0%50.0%
33.33%63.75588,16925.0%50.0%
33.33%61.867512,09650.0%25.0%
83.33%62.847011,681100.0%75.0%
33.33%63.862712,5550.0%40.0%
50.00%64.377213,79866.7%33.3%
33.33%61.956810,50450.0%25.0%
40.00%53.17859,31033.3%50.0%
80.00%51.48609,54666.7%100.0%
60.00%53.275111,74766.7%50.0%
20.00%54.85999,3190.0%50.0%
40.00%54.970312,9070.0%40.0%
40.00%52.18638,0880.0%66.7%
60.00%53.847512,861100.0%0.0%
20.00%55.61,02111,3140.0%50.0%
20.00%54.96469,34225.0%0.0%
80.00%55.389713,097100.0%66.7%
80.00%55.486011,002100.0%50.0%
80.00%53.05319,58866.7%100.0%
60.00%54.758111,34450.0%66.7%

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Senna vs Seraphine - Frequently Asked Questions

How does Senna do against Seraphine in League of Legends?

Seraphine wins the Senna vs Seraphine matchup with a 50.2% win rate compared to Senna's 49.8%, a 0.4 percentage point difference. This data is based on 478 recent ranked games in patch 26.11.

How does Senna do against Seraphine in the early game?

In the early game, Seraphine has the advantage against Senna with a 51.6% win rate versus 48.4%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Senna do against Seraphine in the late game?

In the late game, Senna takes over the Senna vs Seraphine matchup with a 51.0% win rate compared to 49.0%. Senna scales better into team fights and objective contests after 25 minutes.

Who wins the Senna vs Seraphine matchup?

Seraphine wins the matchup against Senna with a 50.2% win rate in League of Legends patch 26.11. The 0.4 percentage point advantage means Seraphine is slightly favored in this lane matchup based on 478 games analyzed.

What is the best Senna build against Seraphine?

The best Senna build against Seraphine includes Statikk Shiv, Black Cleaver, Hexoptics C44 with Boots of Swiftness. This build achieves a 75.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Senna runes against Seraphine?

The best Senna runes against Seraphine use the Sorcery primary tree with Inspiration secondary. This rune setup achieves a 68.4% win rate in the Senna vs Seraphine matchup. See the full rune breakdown in the matchup comparison above.

Does Senna counter Seraphine?

No, Senna struggles against Seraphine with only a 49.8% win rate. Seraphine has the advantage in this matchup. Senna players should focus on safe farming and avoiding extended trades to minimize Seraphine's lead.

How do I play Senna against Seraphine?

When playing Senna against Seraphine, play cautiously and avoid Seraphine's power spikes. Focus on safe farming — you outscale Seraphine in the late game. Use the matchup-specific build and runes above to optimize your chances.