Senna - League of Legends Champion
Win Rate
49.7%
Pick Rate
4.6%

Sennavs Milio

CSupportMarksman
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 19, 2026
MethodologyData Methodology

Senna vs Milio is a decisive matchup in LoL patch 26.7. Senna wins with a 54.1% win rate (+8.2%) over Milio based on 85 games. Senna holds the advantage in both the early and late game. Below you'll find the best Senna build, runes, laning stats, and strategies for the Senna vs Milio matchup.

Senna Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Senna performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Milio - 54.1% win rateMilio(54.1%)
Senna - 54.1% win rate in this matchup
Senna
54.1% WR
VS
Milio vs Senna matchup - 45.9% win rate
Milio
45.9% WR

Who Wins the Senna vs Milio Matchup?

Senna wins the Senna vs Milio matchup
Winner
Senna
Matches: 85
54.1%
Win Rate
45.9%
1.5
CS / min
0.9
557
DMG / min
214
10,241
Gold / game
8,388
563
Heal / min
459
346
DMG Mitigated / min
340
1.2
CC / min
0.7
50.0%
Early Game WR
50.0%
57.8%
Late Game WR
42.2%

Senna vs Milio Matchup Summary

The Senna vs Milio matchup is a decisive matchup in League of Legends ranked play. Based on 85 recent matches analyzed, Senna wins with a 54.1% win rate compared to Milio's 45.9%, giving Senna a 8.2 percentage point advantage. Senna dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Milio players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in damage output, where Senna leads by 343 DMG/min — a difference that heavily influences the outcome of trades and skirmishes. Senna players can confidently pick into Milio and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Milio away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Senna vs Milio Laning Phase Breakdown

Senna wins the laning phase against Milio in League of Legends

Senna is favored during the laning phase against Milio, winning 5 out of 5 key stat categories. Senna holds advantages in farming, damage, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
1.5Senna
0.9Milio
Senna edges out Milio by 0.6 CS per minute — a moderate farming advantage that adds up to roughly 9 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Senna.
Damage
557Senna
214Milio
Senna heavily out-damages Milio by 343 DMG/min, dominating both short trades and all-in fights. Milio should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Senna's sustained damage advantage take over.
Economy
10,241Senna
8,388Milio
Senna generates a commanding 1,853 more gold per game than Milio. This substantial economic advantage means Senna consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Milio should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.2Senna
0.7Milio
Senna provides 0.5 seconds more crowd control per minute than Milio, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Senna coordinate with their jungler and control the pace of skirmishes.
Sustain
909Senna
800Milio
Senna heals and mitigates 109 more damage per minute than Milio, providing moderate extra durability. This sustain edge allows Senna to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Milio.

Best Senna Build Against Milio

Boots of Swiftness is the optimal boots choice against Milio, providing the mobility and stats Senna needs most in this matchup. The top-performing core items for Senna against Milio are Rapid Firecannon, Black Cleaver and Infinity Edge. This combination gives Senna an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 4 games — well above average and making it the top item path against Milio. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Senna vs Milio matchup.

Early Game vs Late Game

Early Game
Senna
50.0%
+0.0% advantage
Senna early game win rateSenna50.0%
Milio early game win rateMilio50.0%
Late Game
Senna
57.8%
+15.6% advantage
Senna late game win rateSenna57.8%
Milio late game win rateMilio42.2%

The early game (first 15 minutes) is a toss-up between Senna and Milio, with Senna holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Senna is far superior in the late game (25+ minutes), boasting a 57.8% win rate — 15.6 points above Milio. Extended games heavily favor Senna, whose kit and scaling make them a dominant force in team fights and objective control.

Senna holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Milio players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Senna Runes Against Milio

Precision rune tree - Senna primary runes vs MilioPrecision
Fleet Footwork - best Senna rune vs MilioPresence of Mind - best Senna rune vs MilioLegend: Alacrity - best Senna rune vs MilioCut Down - best Senna rune vs Milio
Resolve rune tree - Senna secondary runes vs MilioResolve
Bone Plating - best Senna rune vs MilioRevitalize - best Senna rune vs Milio
66.7% WR

Running Precision primary with Resolve secondary allows Senna to press their advantage against Milio, amplifying the strengths that make this a favorable matchup.


Senna matchup data for League of Legends patch 26.7. The table below shows Senna's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Senna build, runes, laning stats, and early vs late game analysis for that specific matchup.

Senna matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
47.56%2251.455810,21750.0%45.5%
51.38%1811.557710,53146.8%54.8%
50.89%1695.577513,46844.9%55.0%
53.85%1691.655010,89748.6%57.9%
48.43%1591.651810,03745.7%50.6%
46.48%1425.977213,18240.9%51.3%
53.96%1391.556610,21550.8%56.9%
46.46%1271.558510,35650.0%43.8%
59.68%1241.557610,15460.0%59.4%
58.47%1181.45839,95557.1%59.7%
49.57%1156.587813,88151.9%47.5%
50.88%1145.981612,83553.6%48.3%
49.12%1146.178212,78941.5%55.7%
48.62%1092.367910,70336.6%55.9%
52.34%1076.288313,40056.1%48.0%
43.40%1066.184713,35437.5%48.3%
44.44%991.452910,19151.2%39.7%
50.51%991.657710,15046.9%54.0%
42.55%941.452910,51535.1%47.4%
48.84%861.45719,95844.2%53.5%
54.12%851.555710,24150.0%57.8%
49.38%816.078412,43353.5%44.7%
57.69%781.44659,34560.9%53.1%
48.68%762.355811,16840.0%54.4%
52.05%731.46059,89852.5%51.5%
44.44%726.288013,61254.8%36.6%
56.94%722.758511,20638.7%70.7%
42.86%701.45219,61243.6%41.9%
59.70%671.45689,46151.4%68.8%
56.45%621.755910,86863.6%52.5%
50.00%626.178013,00832.1%64.7%
42.11%571.950310,77833.3%47.2%
56.36%552.153811,59855.6%56.8%
47.06%511.46859,61034.6%60.0%
54.90%511.366410,89141.7%66.7%
48.00%501.665310,52550.0%46.1%
45.83%485.679114,32253.3%42.4%
51.06%475.784912,93544.0%59.1%
53.33%456.175013,70643.8%58.6%
58.14%436.384512,97069.2%41.2%
39.02%411.559310,86537.5%40.0%
43.59%391.569712,29841.7%44.4%
48.72%391.56049,81963.6%29.4%
60.00%356.589014,81666.7%56.5%
40.00%351.464010,05850.0%31.6%
55.88%341.35429,23359.1%50.0%
51.61%316.187513,86036.8%75.0%
50.00%281.754410,52950.0%50.0%
60.71%286.490314,33153.9%66.7%
50.00%263.374512,44637.5%55.6%
41.67%246.184613,02233.3%50.0%
50.00%242.157311,24850.0%50.0%
45.45%221.462710,22355.6%38.5%
63.64%226.277813,82480.0%50.0%
42.86%215.574611,73750.0%33.3%
55.00%206.295213,00370.0%40.0%
50.00%206.988813,62854.5%44.4%
50.00%185.272912,60662.5%40.0%
66.67%181.259210,65971.4%63.6%
64.71%171.871211,27677.8%50.0%
26.67%151.85137,91340.0%0.0%
46.15%133.059410,69233.3%57.1%
38.46%136.282613,43142.9%33.3%
50.00%122.062411,59980.0%28.6%
58.33%125.754212,02366.7%33.3%
58.33%121.46798,55860.0%57.1%
36.36%111.44259,59016.7%60.0%
72.73%114.51,01110,58860.0%83.3%
45.45%111.84269,88240.0%50.0%
63.64%112.961811,07460.0%66.7%
40.00%106.083613,30460.0%20.0%
60.00%102.356210,70160.0%60.0%
50.00%103.678010,68960.0%40.0%
77.78%96.677114,58380.0%75.0%
66.67%92.276511,77650.0%71.4%
25.00%83.669611,5340.0%40.0%
75.00%81.353712,18466.7%80.0%
37.50%81.169011,5090.0%50.0%
14.29%73.665310,92850.0%0.0%
71.43%71.25269,68875.0%66.7%
50.00%64.866012,36766.7%33.3%
40.00%54.373311,81033.3%50.0%
0.00%52.95609,6090.0%0.0%
60.00%56.470814,61333.3%100.0%
60.00%52.975613,365100.0%50.0%
60.00%56.276314,10050.0%66.7%
40.00%51.745511,50350.0%33.3%
60.00%52.379614,391100.0%50.0%

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Senna vs Milio - Frequently Asked Questions

How does Senna do against Milio in League of Legends?

Senna wins the Senna vs Milio matchup with a 54.1% win rate compared to Milio's 45.9%, a 8.2 percentage point difference. This data is based on 85 recent ranked games in patch 26.7.

How does Senna do against Milio in the early game?

In the early game, Senna has the advantage against Milio with a 50.0% win rate versus 50.0%. Senna players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Senna do against Milio in the late game?

In the late game, Senna takes over the Senna vs Milio matchup with a 57.8% win rate compared to 42.2%. Senna scales better into team fights and objective contests after 25 minutes.

Who wins the Senna vs Milio matchup?

Senna wins the matchup against Milio with a 54.1% win rate in League of Legends patch 26.7. The 8.2 percentage point advantage means Senna is significantly favored in this lane matchup based on 85 games analyzed.

What is the best Senna build against Milio?

The best Senna build against Milio includes Rapid Firecannon, Black Cleaver, Infinity Edge with Boots of Swiftness. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Senna runes against Milio?

The best Senna runes against Milio use the Precision primary tree with Resolve secondary. This rune setup achieves a 66.7% win rate in the Senna vs Milio matchup. See the full rune breakdown in the matchup comparison above.

Does Senna counter Milio?

Yes, Senna has a favorable matchup against Milio with a 54.1% win rate. Senna strongly counters Milio in lane based on current patch 26.7 data.

How do I play Senna against Milio?

When playing Senna against Milio, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.