- Win Rate
- 51.2%
- Pick Rate
- 2.8%
- Ban Rate
- 1.8%
Senna vs Milio
- Patch
- 26.21
- Games
- 5,610
- Lane
- All Lanes
- Tier
- All Tiers
- Last Updated
- Nov 3, 2026 UTC
- Author
- Dakota Chinnick
- Methodology
- Data Methodology
Senna vs Milio is a moderate matchup in LoL patch 26.21. Milio wins with a 52.4% win rate (+4.7%) over Senna based on 170 games. Milio holds the advantage in both the early and late game. Below you'll find the best Senna build, runes, laning stats, and strategies for the Senna vs Milio matchup.
Senna Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Senna performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who wins Senna vs Milio?
Senna wins 48.1% of these games. With this many games the true rate is most likely between 40.6% and 55.8% (95% range).
- Expected
- 49.6% From both champions' overall Support win rates
- Matchup effect
- −1.4 pts Observed minus expected
- Sample
- 162 games Lane: Support
- vs patch 26.20
- −4.1 pts Within normal patch-to-patch noise
Lane: Support · Ranked Solo/Duo & Flex · North America server · All ranks · Patch 26.21 · Oct 27 – Nov 3
Key takeaways
- Current data slightly favors Milio, but the sample is too limited for a strong conclusion: Senna wins 48.1% of 162 games (95% range 40.6–55.8%).
- Both champions' overall Support win rates predict 49.6% for Senna; the result is within the margin of error of that, so this matchup mostly reflects the two champions' general strength.
- Senna usually wins the lane: 646 gold ahead of Milio at 15 minutes on average (161 games with a 15-minute snapshot).
- Senna players pick Serpent's Fang far more often against Milio: 5.5% of their other Support games, 15.4% here.
How we calculate this
Games: ranked Solo/Duo and Flex games on the North America server from the patch shown. Remakes (games under 5 minutes) are excluded.
A game only counts when Senna and Milio played the same position on opposite teams, so roaming, lane swaps within a team or a champion merely being in the same game never count as this matchup.
The 95% range is a Wilson score interval. Confidence comes from how wide that range is: within ±3 points is very high, ±5 high, ±8 moderate, anything wider low. Below 20 games a matchup is not classified at all.
Expected win rate combines both champions’ win rates in this lane (same games and filters) with the log5 formula: E = A(1−B) / (A(1−B) + B(1−A)). Matchup effect = observed − expected.
"What changes" compares Senna's choices in this matchup with the same champion's other games in the same lane, and lists a change only when it is at least 3 points and statistically significant (two-proportion z-test, |z| ≥ 2, 20+ games).
Results are not split by rank: the sample per rank is too small for honest per-rank matchup numbers.
Senna vs Milio Laning Stats
At 15 minutes
Whole-game averages
Senna vs Milio Win Rate by Game Length
Senna's win rate against Milio by game length. The dot is the win rate, the bar its 95% range and the dashed line the champion's usual win rate at that length. Lengths with fewer than 25 games are left blank.
No game length stands out: Senna's results against Milio in short and long games are within the margin of error of each other.
Senna vs Milio Power Spikes
Who is ahead at each stage, measured from these games. A stage reads "Even" when the difference is inside the margin of error, and "Insufficient data" when there are too few games to tell.
- Lane (15 min)SennaSenna gold at 15: +646
- First itemEvenSenna: 13.5 min · Milio: 13.4 min
- Games under 20 minInsufficient data
- 20–30 min gamesEvenSenna wins 46.9% of 64 games
- 30+ min gamesEvenSenna wins 48.8% of 84 games
What Senna Changes Against Milio
Choices Senna players make noticeably more or less often in this matchup than in their other Support games.
Serpent's FangItemUsually5.5%vs Milio15.4%+10.0 pts52.0% WR here
Deathfire TouchKeystoneUsually69.2%vs Milio77.2%+8.0 pts48.8% WR here
Infinity EdgeItemUsually17.7%vs Milio10.5%−7.2 pts
Fleet FootworkKeystoneUsually18.7%vs Milio12.3%−6.3 pts45.0% WR here
Berserker's GreavesBootsUsually11.5%vs Milio6.2%−5.3 pts
Best Senna Build vs Milio
Usual Senna build (Support)
77.8% win rate · 36 games
Limited sample: 22 of 76 games finished this exact core, so treat it as an observation rather than a recommendation.
- Senna usually completes Black Cleaver first, at 13.5 min (median of 81 games).
- Milio usually completes Echoes of Helia first, at 13.4 min (median of 69 games).
- Skill priority: Q > W > E — the same as usual.
Builds are ranked by the lower edge of their win rate range, not the raw win rate, so a build seen in a handful of wins never outranks a proven one.
Best Senna Runes vs Milio
Usual Senna runes (Support)
Deathfire Touch
55.8% win rate · 491 games
Against Milio
Deathfire Touch
50.0% win rate · 30 games
Plan your Senna draft in Draft Lab
Draft Lab lays out both teams lane by lane with live matchup win rates, damage profiles and game-phase lean, and suggests picks and bans from current meta data.
- Full 5v5 draft board
- Lane matchup win rates
- Pick and ban suggestions
Senna matchup data for League of Legends patch 26.21. The table below shows Senna's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Senna build, runes, laning stats, and early vs late game analysis for that specific matchup.
Other Senna Matchups
Hardest for Senna
Easiest for Senna
Win rate and games for each matchup. Lists are ranked by the edge of the 95% range so small samples cannot top them; matchups with at least 50 games only.
Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.
Senna vs Milio FAQ - Patch 26.21
Who wins Senna vs Milio?
Current data slightly favors Milio, but the sample is too limited for a strong conclusion: Senna wins 48.1% of 162 games (95% range 40.6–55.8%).
What is Senna's win rate against Milio?
Senna wins 48.1% of 162 Support games against Milio on patch 26.21 (95% range 40.6–55.8%). Based on both champions' overall Support win rates, 49.6% would be expected.
Does Senna counter Milio?
Not clearly. Senna wins 48.1% of 162 games against Milio, and the 95% range (40.6–55.8%) includes 50%, so neither champion reliably counters the other on current data.
Who wins lane, Senna or Milio?
Senna usually wins the lane: 646 gold ahead of Milio at 15 minutes on average (161 games with a 15-minute snapshot).
Does Senna outscale Milio?
There are too few games of each length to tell yet.
When is Milio strongest against Senna?
On current data there is no stage of the game where Milio is ahead of Senna beyond the margin of error.
What should Senna build against Milio?
The most successful Senna core against Milio is Rapid Firecannon, Statikk Shiv, Black Cleaver (59.1% over 22 games). The biggest change against Milio: Serpent's Fang (5.5% usually, 15.4% here).
What runes should Senna use against Milio?
Deathfire Touch with Sorcery and Precision — 50.0% over 30 games against Milio. The biggest change against Milio: Deathfire Touch (69.2% usually, 77.2% here).