
- Win Rate
- 51.2%
- Pick Rate
- 2.8%
- Ban Rate
- 1.8%
Senna vs Nautilus
- Patch
- 26.21
- Games
- 5,610
- Lane
- All Lanes
- Tier
- All Tiers
- Last Updated
- Nov 3, 2026 UTC
- Author
- Dakota Chinnick
- Methodology
- Data Methodology
Senna vs Nautilus is a decisive matchup in LoL patch 26.21. Senna wins with a 52.9% win rate (+5.7%) over Nautilus based on 244 games. Senna holds the advantage in both the early and late game. Below you'll find the best Senna build, runes, laning stats, and strategies for the Senna vs Nautilus matchup.
Senna Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Senna performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.


Who wins Senna vs Nautilus?
Senna wins 52.1% of these games. With this many games the true rate is most likely between 45.8% and 58.5% (95% range).
- Expected
- 52.8% From both champions' overall Support win rates
- Matchup effect
- −0.6 pts Observed minus expected
- Sample
- 234 games Lane: Support
- vs patch 26.20
- +7.6 pts Within normal patch-to-patch noise
Lane: Support · Ranked Solo/Duo & Flex · North America server · All ranks · Patch 26.21 · Oct 27 – Nov 3
Key takeaways
- Current data slightly favors Senna, but the sample is too limited for a strong conclusion: Senna wins 52.1% of 234 games (95% range 45.8–58.5%).
- Both champions' overall Support win rates predict 52.8% for Senna; the result is within the margin of error of that, so this matchup mostly reflects the two champions' general strength.
- Senna usually wins the lane: 422 gold ahead of Nautilus at 15 minutes on average (230 games with a 15-minute snapshot).
- Senna players pick Health Potion + Health Potion much less often against Nautilus: 30.2% of their other Support games, 22.5% here.
How we calculate this
Games: ranked Solo/Duo and Flex games on the North America server from the patch shown. Remakes (games under 5 minutes) are excluded.
A game only counts when Senna and Nautilus played the same position on opposite teams, so roaming, lane swaps within a team or a champion merely being in the same game never count as this matchup.
The 95% range is a Wilson score interval. Confidence comes from how wide that range is: within ±3 points is very high, ±5 high, ±8 moderate, anything wider low. Below 20 games a matchup is not classified at all.
Expected win rate combines both champions’ win rates in this lane (same games and filters) with the log5 formula: E = A(1−B) / (A(1−B) + B(1−A)). Matchup effect = observed − expected.
"What changes" compares Senna's choices in this matchup with the same champion's other games in the same lane, and lists a change only when it is at least 3 points and statistically significant (two-proportion z-test, |z| ≥ 2, 20+ games).
Results are not split by rank: the sample per rank is too small for honest per-rank matchup numbers.
Senna vs Nautilus Laning Stats
At 15 minutes
Whole-game averages
Senna vs Nautilus Win Rate by Game Length
Senna's win rate against Nautilus by game length. The dot is the win rate, the bar its 95% range and the dashed line the champion's usual win rate at that length. Lengths with fewer than 25 games are left blank.
No game length stands out: Senna's results against Nautilus in short and long games are within the margin of error of each other.
Senna vs Nautilus Power Spikes
Who is ahead at each stage, measured from these games. A stage reads "Even" when the difference is inside the margin of error, and "Insufficient data" when there are too few games to tell.
- Lane (15 min)SennaSenna gold at 15: +422
- First itemNautilusSenna: 13.8 min · Nautilus: 13.3 min
- Games under 20 minInsufficient data
- 20–30 min gamesEvenSenna wins 53.1% of 96 games
- 30+ min gamesEvenSenna wins 50.4% of 123 games
What Senna Changes Against Nautilus
Choices Senna players make noticeably more or less often in this matchup than in their other Support games.

Health Potion + Health PotionStarting itemsUsually30.2%vs Nautilus22.5%−7.7 pts60.0% WR here
Fleet FootworkKeystoneUsually18.7%vs Nautilus12.8%−5.9 pts56.7% WR here
Health Scaling (defense)Stat shardUsually22.4%vs Nautilus16.7%−5.7 pts43.6% WR here
Best Senna Build vs Nautilus
Usual Senna build (Support)
77.8% win rate · 36 games
Against Nautilus
66.7% win rate · 36 games
Limited sample: 36 of 110 games finished this exact core, so treat it as an observation rather than a recommendation.
- Senna usually completes Black Cleaver first, at 13.8 min (median of 112 games).
- Nautilus usually completes Locket of the Iron Solari first, at 13.3 min (median of 157 games).
- Skill priority: Q > W > E — the same as usual.
Builds are ranked by the lower edge of their win rate range, not the raw win rate, so a build seen in a handful of wins never outranks a proven one.
Best Senna Runes vs Nautilus
Plan your Senna draft in Draft Lab
Draft Lab lays out both teams lane by lane with live matchup win rates, damage profiles and game-phase lean, and suggests picks and bans from current meta data.
- Full 5v5 draft board
- Lane matchup win rates
- Pick and ban suggestions

Senna matchup data for League of Legends patch 26.21. The table below shows Senna's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Senna build, runes, laning stats, and early vs late game analysis for that specific matchup.
Other Senna Matchups
Hardest for Senna
Easiest for Senna
Win rate and games for each matchup. Lists are ranked by the edge of the 95% range so small samples cannot top them; matchups with at least 50 games only.
Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.
Senna vs Nautilus FAQ - Patch 26.21
Who wins Senna vs Nautilus?
Current data slightly favors Senna, but the sample is too limited for a strong conclusion: Senna wins 52.1% of 234 games (95% range 45.8–58.5%).
What is Senna's win rate against Nautilus?
Senna wins 52.1% of 234 Support games against Nautilus on patch 26.21 (95% range 45.8–58.5%). Based on both champions' overall Support win rates, 52.8% would be expected.
Does Senna counter Nautilus?
Not clearly. Senna wins 52.1% of 234 games against Nautilus, and the 95% range (45.8–58.5%) includes 50%, so neither champion reliably counters the other on current data.
Who wins lane, Senna or Nautilus?
Senna usually wins the lane: 422 gold ahead of Nautilus at 15 minutes on average (230 games with a 15-minute snapshot).
Does Senna outscale Nautilus?
There are too few games of each length to tell yet.
When is Nautilus strongest against Senna?
Nautilus is measurably ahead in: First item.
What should Senna build against Nautilus?
The most successful Senna core against Nautilus is Rapid Firecannon, Statikk Shiv, Black Cleaver (66.7% over 36 games). The biggest change against Nautilus: Health Potion + Health Potion (30.2% usually, 22.5% here).
What runes should Senna use against Nautilus?
Deathfire Touch with Sorcery and Precision — 57.1% over 42 games against Nautilus. The biggest change against Nautilus: Fleet Footwork (18.7% usually, 12.8% here).
