
Syndra Runes
Best Syndra runes for LoL Patch 26.1 - First Strike from the Inspiration tree with Sorcery secondary (66.7% WR, 0.7% pick rate). Syndra's optimal primary runes are First Strike, Magical Footwear, Triple Tonic, Cosmic Insight. Secondary tree: Manaflow Band, Transcendence.


Transcendent
Syndra collects Splinters of Wrath from gaining levels and damaging enemies which upgrade her abilities.
Dark Sphere: Syndra can hold an additional charge
Force of Will: Bonus true damage.
Scatter the Weak: Increased width and slows all targets
Unleashed Power: Executes low health targets

Dark Sphere
Syndra conjures a Dark Sphere dealing magic damage. The sphere remains and can be manipulated by her other powers.
Cost:- 40/
- 45/
- 50/
- 55/
- 60
Cooldown:- 7
Range:- 800


Force of Will
Syndra picks up and throws a Dark Sphere or enemy minion dealing magic damage and slowing the Move Speed of enemies.
Cost:- 60/
- 70/
- 80/
- 90/
- 100
Cooldown:- 12/
- 11/
- 10/
- 9/
- 8
Range:- 925


Scatter the Weak
Syndra knocks enemies and Dark Spheres back dealing magic damage. Enemies hit by Dark Spheres become stunned.
Cost:- 50
Cooldown:- 15
Range:- 650


Unleashed Power
Syndra bombards an enemy Champion with all of her Dark Spheres.
Cost:- 100
Cooldown:- 120/
- 100/
- 80
Range:- 675
- Mage
Syndra performs best with First Strike as the keystone rune from the Inspiration tree. Syndra's optimal primary runes are First Strike, Magical Footwear, Triple Tonic, Cosmic Insight. Syndra's secondary rune tree is Sorcery with Manaflow Band, Transcendence. This rune setup achieves a 66.67% win rate (+16.4% win rate difference) with a 0.7% pick rate across 30 Syndra games.
Primary Tree
Inspiration
First StrikeAttacks or abilities against an enemy champion within 0.25s of entering champion combat grant 10 gold and First Strike for 3 seconds, causing you to deal
Cooldown:
Magical FootwearYou get free Slightly Magical Footwear at 12 min, but you cannot buy boots before then. For each takedown you acquire the boots 45s sooner.
Slightly Magical Footwear grants you an additional
Triple TonicUpon reaching level 3, gain an Elixir of Avarice.
Upon reaching level 6, gain an Elixir of Force.
Upon reaching level 9, gain an Elixir of Skill.
Cosmic Insight+
+
Manaflow BandHitting an enemy champion with an ability permanently increases your maximum mana by 25, up to 250 mana.
After reaching 250 bonus mana, restore 1% of your missing mana every 5 seconds.
Cooldown: 15 seconds
TranscendenceGain bonuses upon reaching the following levels:
Level 5: +5
Level 8: +5
Level 11: On Champion takedown, reduce the remaining cooldown of basic abilities by 20%.
This alternative Syndra rune build uses First Strike as the keystone from the Inspiration tree. The primary runes are First Strike, Magical Footwear, Triple Tonic, Jack Of All Trades. Syndra's secondary rune tree is Sorcery with Manaflow Band, Transcendence. This setup achieves a 66.67% win rate (+16.4% win rate difference) with a 0.6% pick rate across 27 games.
Primary Tree
Inspiration
First StrikeAttacks or abilities against an enemy champion within 0.25s of entering champion combat grant 10 gold and First Strike for 3 seconds, causing you to deal
Cooldown:
Magical FootwearYou get free Slightly Magical Footwear at 12 min, but you cannot buy boots before then. For each takedown you acquire the boots 45s sooner.
Slightly Magical Footwear grants you an additional
Triple TonicUpon reaching level 3, gain an Elixir of Avarice.
Upon reaching level 6, gain an Elixir of Force.
Upon reaching level 9, gain an Elixir of Skill.
Jack Of All TradesFor each different stat gained from items, gain one Jack stack. Each stack grants you
Gain 10 or 25 bonus
Manaflow BandHitting an enemy champion with an ability permanently increases your maximum mana by 25, up to 250 mana.
After reaching 250 bonus mana, restore 1% of your missing mana every 5 seconds.
Cooldown: 15 seconds
TranscendenceGain bonuses upon reaching the following levels:
Level 5: +5
Level 8: +5
Level 11: On Champion takedown, reduce the remaining cooldown of basic abilities by 20%.
Syndra Runes - Frequently Asked Questions
What are the best Syndra runes in patch 26.1?
The best Syndra runes in patch 26.1 use the Inspiration tree with First Strike, Magical Footwear, Triple Tonic, and Cosmic Insight, and the Sorcery tree with Manaflow Band and Transcendence. This rune setup achieves a 66.7% win rate with a 0.7% pick rate.
What is the win rate for Syndra's best rune page?
Syndra's best rune page has a 66.7% win rate in patch 26.1, which is +16.4% compared to Syndra's average win rate. This rune setup has a 0.7% pick rate among Syndra players.
What keystone should I use on Syndra?
First Strike from the Inspiration tree is the best keystone rune for Syndra in patch 26.1. This keystone synergizes well with Syndra's kit and provides a 66.7% win rate.
What is Syndra's primary rune tree?
Syndra's primary rune tree is Inspiration. The optimal Inspiration runes for Syndra are First Strike, Magical Footwear, Triple Tonic, and Cosmic Insight, with First Strike being the keystone of choice.
What is Syndra's secondary rune tree?
Syndra's best secondary rune tree is Sorcery. The recommended Sorcery runes are Manaflow Band and Transcendence, which complement Syndra's Inspiration primary tree.
What are alternative rune setups for Syndra?
An alternative Syndra rune setup uses First Strike from the Inspiration tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.
How popular are Syndra's runes?
Syndra's top rune page has a 0.7% pick rate in patch 26.1. This indicates that 0.7% of Syndra players use the First Strike setup with Inspiration and Sorcery trees.





























