
Syndra Runes
The top Syndra runes in LoL patch 25.23 are First Strike, Cash Back, Triple Tonic, Jack Of All Trades for Syndra's primary runes. Syndra's runes in his secondary tree best utilizes Legend: Haste and Coup de Grace. These Syndra rune choices provide the best Syndra rune build for ranked.


Transcendent
Syndra collects Splinters of Wrath from gaining levels and damaging enemies which upgrade her abilities.
Dark Sphere: Syndra can hold an additional charge
Force of Will: Bonus true damage.
Scatter the Weak: Increased width and slows all targets
Unleashed Power: Executes low health targets

Dark Sphere
Syndra conjures a Dark Sphere dealing magic damage. The sphere remains and can be manipulated by her other powers.
Cost:- 40/
- 45/
- 50/
- 55/
- 60
Cooldown:- 7
Range:- 800


Force of Will
Syndra picks up and throws a Dark Sphere or enemy minion dealing magic damage and slowing the Move Speed of enemies.
Cost:- 60/
- 70/
- 80/
- 90/
- 100
Cooldown:- 12/
- 11/
- 10/
- 9/
- 8
Range:- 925


Scatter the Weak
Syndra knocks enemies and Dark Spheres back dealing magic damage. Enemies hit by Dark Spheres become stunned.
Cost:- 50
Cooldown:- 15
Range:- 650


Unleashed Power
Syndra bombards an enemy Champion with all of her Dark Spheres.
Cost:- 100
Cooldown:- 120/
- 100/
- 80
Range:- 675
- Mage

Syndra performs best with First Strike as the keystone rune. The optimal primary runes for Syndra include First Strike, Cash Back, Triple Tonic. This rune setup achieves a 1.00% win rate across 1 Syndra games.
Primary Tree
InspirationThis alternative Syndra rune build uses Electrocute as the keystone. This setup provides a different playstyle for Syndra and achieves a 1.00% win rate. Consider this rune page when facing specific matchups or team compositions.
Primary Tree
DominationSyndra Runes - Frequently Asked Questions
What are the best Syndra runes?
The best Syndra runes in patch 25.23 are First Strike, Cash Back, Triple Tonic, and Jack Of All Trades for the primary tree, and Legend: Haste and Coup de Grace for the secondary tree. These runes provide optimal performance for Syndra.
What keystone should I use on Syndra?
First Strike is the best keystone rune for Syndra. This keystone synergizes well with Syndra's abilities and provides maximum value in most matchups.
What are Syndra's secondary runes?
Syndra's best secondary runes are Legend: Haste and Coup de Grace. These secondary runes complement Syndra's primary rune choices and enhance overall effectiveness.
Can I use different rune setups on Syndra?
Yes, Syndra can utilize different rune setups depending on matchup and playstyle. While First Strike is most popular, alternative keystones may work better in specific situations.



















































